##gff-version 3
P40645	UniProtKB	Chain	1	827	.	.	.	ID=PRO_0000048730;Note=Transcription factor SOX-6	
P40645	UniProtKB	DNA binding	620	688	.	.	.	Note=HMG box;Ontology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU00267	
P40645	UniProtKB	Region	1	51	.	.	.	Note=Disordered;Ontology_term=ECO:0000256;evidence=ECO:0000256|SAM:MobiDB-lite	
P40645	UniProtKB	Region	334	361	.	.	.	Note=Disordered;Ontology_term=ECO:0000256;evidence=ECO:0000256|SAM:MobiDB-lite	
P40645	UniProtKB	Region	379	470	.	.	.	Note=Disordered;Ontology_term=ECO:0000256;evidence=ECO:0000256|SAM:MobiDB-lite	
P40645	UniProtKB	Region	752	772	.	.	.	Note=Disordered;Ontology_term=ECO:0000256;evidence=ECO:0000256|SAM:MobiDB-lite	
P40645	UniProtKB	Region	786	827	.	.	.	Note=Disordered;Ontology_term=ECO:0000256;evidence=ECO:0000256|SAM:MobiDB-lite	
P40645	UniProtKB	Coiled coil	184	262	.	.	.	Ontology_term=ECO:0000255;evidence=ECO:0000255	
P40645	UniProtKB	Compositional bias	21	37	.	.	.	Note=Basic and acidic residues;Ontology_term=ECO:0000256;evidence=ECO:0000256|SAM:MobiDB-lite	
P40645	UniProtKB	Compositional bias	344	361	.	.	.	Note=Basic and acidic residues;Ontology_term=ECO:0000256;evidence=ECO:0000256|SAM:MobiDB-lite	
P40645	UniProtKB	Compositional bias	797	812	.	.	.	Note=Acidic residues;Ontology_term=ECO:0000256;evidence=ECO:0000256|SAM:MobiDB-lite	
P40645	UniProtKB	Modified residue	119	119	.	.	.	Note=Phosphothreonine;Ontology_term=ECO:0007744;evidence=ECO:0007744|PubMed:21183079;Dbxref=PMID:21183079	
P40645	UniProtKB	Modified residue	399	399	.	.	.	Note=Phosphoserine;Ontology_term=ECO:0007744;evidence=ECO:0007744|PubMed:21183079;Dbxref=PMID:21183079	
P40645	UniProtKB	Modified residue	401	401	.	.	.	Note=Phosphothreonine;Ontology_term=ECO:0007744;evidence=ECO:0007744|PubMed:21183079;Dbxref=PMID:21183079	
P40645	UniProtKB	Modified residue	439	439	.	.	.	Note=Phosphoserine;Ontology_term=ECO:0007744;evidence=ECO:0007744|PubMed:21183079;Dbxref=PMID:21183079	
P40645	UniProtKB	Modified residue	442	442	.	.	.	Note=Phosphoserine;Ontology_term=ECO:0007744;evidence=ECO:0007744|PubMed:21183079;Dbxref=PMID:21183079	
P40645	UniProtKB	Cross-link	404	404	.	.	.	Note=Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO);Ontology_term=ECO:0000250;evidence=ECO:0000250	
P40645	UniProtKB	Cross-link	417	417	.	.	.	Note=Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO);Ontology_term=ECO:0000250;evidence=ECO:0000250	
P40645	UniProtKB	Alternative sequence	327	367	.	.	.	ID=VSP_002198;Note=In isoform 2. Missing;Ontology_term=ECO:0000303;evidence=ECO:0000303|PubMed:7791783;Dbxref=PMID:7791783	
P40645	UniProtKB	Mutagenesis	161	161	.	.	.	Note=Decreased localization to the nucleus. No effect on homodimerization. No effect on transcription cis-regulatory region binding. No effect on DNA-binding transcription factor activity. W->C;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:32442410;Dbxref=PMID:32442410	
P40645	UniProtKB	Mutagenesis	624	624	.	.	.	Note=Decreased localization to the nucleus. No effect on homodimerization. Decreased transcription cis-regulatory region binding. Loss of DNA-binding transcription factor activity. Acts as a dominant negative. M->T;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:32442410;Dbxref=PMID:32442410	
P40645	UniProtKB	Mutagenesis	658	658	.	.	.	Note=Loss of localization to the nucleus. Loss of transcription cis-regulatory region binding. Loss of DNA-binding transcription factor activity. Acts as a dominant negative. W->R;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:32442410;Dbxref=PMID:32442410	
P40645	UniProtKB	Mutagenesis	765	765	.	.	.	Note=Increased localization to the nucleus. Decreased transcription cis-regulatory region binding. No effect on DNA-binding transcription factor activity. S->L;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:32442410;Dbxref=PMID:32442410	
P40645	UniProtKB	Sequence conflict	312	313	.	.	.	Note=MA->SS;Ontology_term=ECO:0000305;evidence=ECO:0000305	
P40645	UniProtKB	Sequence conflict	632	632	.	.	.	Note=K->R;Ontology_term=ECO:0000305;evidence=ECO:0000305