ID   HMGH_IIV6               Reviewed;         242 AA.
AC   P40628; Q91FC4;
DT   01-FEB-1995, integrated into UniProtKB/Swiss-Prot.
DT   14-DEC-2011, sequence version 2.
DT   27-MAR-2024, entry version 91.
DE   RecName: Full=High mobility group protein homolog;
GN   Name=EF1; OrderedLocusNames=401R;
OS   Invertebrate iridescent virus 6 (IIV-6) (Chilo iridescent virus).
OC   Viruses; Varidnaviria; Bamfordvirae; Nucleocytoviricota; Megaviricetes;
OC   Pimascovirales; Iridoviridae; Betairidovirinae; Iridovirus.
OX   NCBI_TaxID=176652;
OH   NCBI_TaxID=6997; Acheta domesticus (House cricket).
OH   NCBI_TaxID=168631; Chilo suppressalis (Asiatic rice borer moth).
OH   NCBI_TaxID=6999; Gryllus bimaculatus (Two-spotted cricket).
OH   NCBI_TaxID=58607; Gryllus campestris.
OH   NCBI_TaxID=7108; Spodoptera frugiperda (Fall armyworm).
RN   [1]
RP   NUCLEOTIDE SEQUENCE.
RX   PubMed=8121799; DOI=10.1093/nar/22.2.158;
RA   Schnitzler P., Hug M., Handermann M., Janssen W., Koonin E.V., Delius H.,
RA   Darai C.;
RT   "Identification of genes encoding zinc finger proteins, non-histone
RT   chromosomal HMG protein homologue, and a putative GTP phosphohydrolase in
RT   the genome of Chilo iridescent virus.";
RL   Nucleic Acids Res. 22:158-166(1994).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=11448171; DOI=10.1006/viro.2001.0963;
RA   Jakob N.J., Mueller K., Bahr U., Darai G.;
RT   "Analysis of the first complete DNA sequence of an invertebrate iridovirus:
RT   coding strategy of the genome of Chilo iridescent virus.";
RL   Virology 286:182-196(2001).
CC   -!- SUBCELLULAR LOCATION: Host nucleus {ECO:0000305}.
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DR   EMBL; L22300; AAA17843.1; -; Unassigned_DNA.
DR   EMBL; AF303741; AAK82261.1; -; Genomic_DNA.
DR   PIR; S71905; S71905.
DR   RefSeq; NP_149864.1; NC_003038.1.
DR   SMR; P40628; -.
DR   GeneID; 1733017; -.
DR   KEGG; vg:1733017; -.
DR   OrthoDB; 10798at10239; -.
DR   Proteomes; UP000001359; Genome.
DR   GO; GO:0042025; C:host cell nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   Gene3D; 1.10.30.10; High mobility group box domain; 2.
DR   InterPro; IPR009071; HMG_box_dom.
DR   InterPro; IPR036910; HMG_box_dom_sf.
DR   PANTHER; PTHR48112; HIGH MOBILITY GROUP PROTEIN DSP1; 1.
DR   PANTHER; PTHR48112:SF36; NON-HISTONE CHROMOSOMAL PROTEIN 6A-RELATED; 1.
DR   Pfam; PF00505; HMG_box; 1.
DR   SMART; SM00398; HMG; 2.
DR   SUPFAM; SSF47095; HMG-box; 2.
DR   PROSITE; PS50118; HMG_BOX_2; 2.
PE   4: Predicted;
KW   DNA-binding; Host nucleus; Reference proteome; Repeat.
FT   CHAIN           1..242
FT                   /note="High mobility group protein homolog"
FT                   /id="PRO_0000048594"
FT   DNA_BIND        54..122
FT                   /note="HMG box 1"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00267"
FT   DNA_BIND        126..197
FT                   /note="HMG box 2"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00267"
FT   CONFLICT        132
FT                   /note="G -> A (in Ref. 2; AAK82261)"
FT                   /evidence="ECO:0000305"
FT   CONFLICT        142..143
FT                   /note="KI -> QGL (in Ref. 2; AAK82261)"
FT                   /evidence="ECO:0000305"
FT   CONFLICT        215..242
FT                   /note="SICSSNVKAIQELIGTTKSSKKNKEIKV -> LVFVLAM (in Ref. 1;
FT                   AAA17843)"
FT                   /evidence="ECO:0000305"
SQ   SEQUENCE   242 AA;  28182 MW;  EE2343DA27F92282 CRC64;
     MKSKKELMDA LNKLVITEIC SIFPDIQRVW EDQEFQKKFA STIGVKPKDV TNVPKRNKSS
     YLFFCQEIRP SIVAEMPDIK PNQVMVHLGK KWSELPLEDR KKYDVMAVED RKRYLASKEA
     NKKLNKPVKI SGYLQFCADE RKIKLKFPDL TTKDITAKLG GMWNDYKKNN PQYLKSKYGY
     EIVEQHYDYE KNEIDKENII PSSHRRKMVP SIPVSICSSN VKAIQELIGT TKSSKKNKEI
     KV
//