P40628 (HMGH_IIV6) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
High mobility group protein homolog

Gene names

Name:	EF1
Ordered Locus Names:	401R

Organism

Invertebrate iridescent virus 6 (IIV-6) (Chilo iridescent virus) [Reference proteome]

Taxonomic identifier

176652 [NCBI]

Taxonomic lineage

Viruses › dsDNA viruses, no RNA stage › Iridoviridae › Iridovirus

Virus host

Acheta domesticus (House cricket) [TaxID: 6997]
Chilo suppressalis (striped riceborer) [TaxID: 168631]
Gryllus bimaculatus (Two-spotted cricket) [TaxID: 6999]
Gryllus campestris [TaxID: 58607]
Spodoptera frugiperda (Fall armyworm) [TaxID: 7108]

Protein attributes

Sequence length	242 AA.
Sequence status	Complete.
Protein existence	Predicted

General annotation (Comments)

Subcellular location	Host nucleus Potential.
Sequence similarities	Contains 2 HMG box DNA-binding domains.

Ontologies

Keywords
Cellular component	Host nucleus
Domain	Repeat
Ligand	DNA-binding
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Cellular_component	host cell nucleus Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular_function	DNA binding Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 242	242	High mobility group protein homolog		PRO_0000048594
Regions
	DNA binding	54 – 122	69	HMG box 1
	DNA binding	126 – 197	72	HMG box 2
Experimental info
	Sequence conflict	132	1	G → A in AAK82261. Ref.2
	Sequence conflict	142 – 143	2	KI → QGL in AAK82261. Ref.2
	Sequence conflict	215 – 242	28	SICSS…KEIKV → LVFVLAM in AAA17843. Ref.1

Sequences

	Sequence		Length	Mass (Da)
	P40628 [UniParc]. Last modified December 14, 2011. Version 2. Checksum: EE2343DA27F92282	FASTA	242	28,182
	10 20 30 40 50 60 MKSKKELMDA LNKLVITEIC SIFPDIQRVW EDQEFQKKFA STIGVKPKDV TNVPKRNKSS 70 80 90 100 110 120 YLFFCQEIRP SIVAEMPDIK PNQVMVHLGK KWSELPLEDR KKYDVMAVED RKRYLASKEA 130 140 150 160 170 180 NKKLNKPVKI SGYLQFCADE RKIKLKFPDL TTKDITAKLG GMWNDYKKNN PQYLKSKYGY 190 200 210 220 230 240 EIVEQHYDYE KNEIDKENII PSSHRRKMVP SIPVSICSSN VKAIQELIGT TKSSKKNKEI KV

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Identification of genes encoding zinc finger proteins, non-histone chromosomal HMG protein homologue, and a putative GTP phosphohydrolase in the genome of Chilo iridescent virus." Schnitzler P., Hug M., Handermann M., Janssen W., Koonin E.V., Delius H., Darai C. Nucleic Acids Res. 22:158-166(1994) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE.
[2]	"Analysis of the first complete DNA sequence of an invertebrate iridovirus: coding strategy of the genome of Chilo iridescent virus." Jakob N.J., Mueller K., Bahr U., Darai G. Virology 286:182-196(2001) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	L22300 Unassigned DNA. Translation: AAA17843.1. AF303741 Genomic DNA. Translation: AAK82261.1.
PIR	S71905.
RefSeq	NP_149864.1. NC_003038.1.
3D structure databases
HSSP	HSSP built from PDB template 1J5N based on UniProtKB P11632.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	1733017.
Phylogenomic databases
ProtClustDB	CLSP2511695.
Family and domain databases
Gene3D	1.10.30.10. 2 hits.
InterPro	IPR009071. HMG_box_dom. [Graphical view]
Pfam	PF00505. HMG_box. 1 hit. [Graphical view]
SMART	SM00398. HMG. 2 hits. [Graphical view]
SUPFAM	SSF47095. HMG-box. 1 hit.
PROSITE	PS50118. HMG_BOX_2. False negative. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

HMGH_IIV6

Accession

Primary (citable) accession number: P40628
Secondary accession number(s): Q91FC4

Entry history

Integrated into UniProtKB/Swiss-Prot:	February 1, 1995
Last sequence update:	December 14, 2011
Last modified:	May 1, 2013
This is version 63 of the entry and version 2 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Viral Protein Annotation Program