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P40625

- HMG_TETPY

UniProt

P40625 - HMG_TETPY

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Protein

High mobility group protein

Gene
HMG
Organism
Tetrahymena pyriformis
Status
Reviewed - Annotation score: 3 out of 5 - Experimental evidence at protein leveli

Functioni

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
DNA bindingi11 – 7969HMG boxAdd
BLAST

GO - Molecular functioni

  1. DNA binding Source: UniProtKB-KW
Complete GO annotation...

Keywords - Ligandi

DNA-binding

Names & Taxonomyi

Protein namesi
Recommended name:
High mobility group protein
Alternative name(s):
Non-histone chromosomal protein
Gene namesi
Name:HMG
OrganismiTetrahymena pyriformis
Taxonomic identifieri5908 [NCBI]
Taxonomic lineageiEukaryotaAlveolataCiliophoraIntramacronucleataOligohymenophoreaHymenostomatidaTetrahymeninaTetrahymenidaeTetrahymena

Subcellular locationi

GO - Cellular componenti

  1. chromosome Source: UniProtKB-SubCell
  2. nucleus Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Chromosome, Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 9999High mobility group proteinPRO_0000048560Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei16 – 161Phosphoserine1 Publication
Modified residuei42 – 421Phosphothreonine Inferred
Modified residuei43 – 431Phosphoserine Inferred

Post-translational modificationi

Phosphorylated at two positions (Ser-16 and Thr-42 or Ser-43), each 6-7%.1 Publication

Keywords - PTMi

Phosphoprotein

Structurei

3D structure databases

ProteinModelPortaliP40625.

Family & Domainsi

Sequence similaritiesi

Family and domain databases

Gene3Di1.10.30.10. 1 hit.
InterProiIPR009071. HMG_box_dom.
[Graphical view]
PfamiPF00505. HMG_box. 1 hit.
[Graphical view]
SMARTiSM00398. HMG. 1 hit.
[Graphical view]
SUPFAMiSSF47095. SSF47095. 1 hit.
PROSITEiPS50118. HMG_BOX_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P40625-1 [UniParc]FASTAAdd to Basket

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GKVKDDKPAP PKRPLSAFFL FKQHNYDQVK KENPNAKITE LTSMIAEKWK   50
HVTEKEKKKY EGLQQEAKAK YEKDMQAYEK KYGKPEKVKK IKKSKKGSK 99
Length:99
Mass (Da):11,627
Last modified:February 1, 1995 - v1
Checksum:i93BFB012A2D3D7FF
GO

Sequence databases

PIRiJU0038.

Cross-referencesi

Sequence databases

PIRi JU0038.

3D structure databases

ProteinModelPortali P40625.
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Family and domain databases

Gene3Di 1.10.30.10. 1 hit.
InterProi IPR009071. HMG_box_dom.
[Graphical view ]
Pfami PF00505. HMG_box. 1 hit.
[Graphical view ]
SMARTi SM00398. HMG. 1 hit.
[Graphical view ]
SUPFAMi SSF47095. SSF47095. 1 hit.
PROSITEi PS50118. HMG_BOX_2. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Tetrahymena HMG nonhistone chromosomal protein. Isolation and amino acid sequence lacking the N- and C-terminal domains of vertebrate HMG 1."
    Hayashi T., Hayashi H., Iwai K.
    J. Biochem. 105:577-581(1989) [PubMed] [Europe PMC] [Abstract]
    Cited for: PROTEIN SEQUENCE, PHOSPHORYLATION AT SER-16; THR-42 AND SER-43.
    Strain: GL.

Entry informationi

Entry nameiHMG_TETPY
AccessioniPrimary (citable) accession number: P40625
Entry historyi
Integrated into UniProtKB/Swiss-Prot: February 1, 1995
Last sequence update: February 1, 1995
Last modified: October 16, 2013
This is version 65 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)

Miscellaneousi

Keywords - Technical termi

Direct protein sequencing

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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