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P40625

- HMG_TETPY

UniProt

P40625 - HMG_TETPY

Protein

High mobility group protein

Gene

HMG

Organism
Tetrahymena pyriformis
Status
Reviewed - Annotation score: 3 out of 5- Experimental evidence at protein leveli
  1. Functioni

    Regions

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    DNA bindingi11 – 7969HMG boxPROSITE-ProRule annotationAdd
    BLAST

    GO - Molecular functioni

    1. DNA binding Source: UniProtKB-KW

    Keywords - Ligandi

    DNA-binding

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    High mobility group protein
    Alternative name(s):
    Non-histone chromosomal protein
    Gene namesi
    Name:HMG
    OrganismiTetrahymena pyriformis
    Taxonomic identifieri5908 [NCBI]
    Taxonomic lineageiEukaryotaAlveolataCiliophoraIntramacronucleataOligohymenophoreaHymenostomatidaTetrahymeninaTetrahymenidaeTetrahymena

    Subcellular locationi

    GO - Cellular componenti

    1. chromosome Source: UniProtKB-SubCell
    2. nucleus Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Chromosome, Nucleus

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 9999High mobility group proteinPRO_0000048560Add
    BLAST

    Amino acid modifications

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Modified residuei16 – 161Phosphoserine1 Publication
    Modified residuei42 – 421Phosphothreonine1 Publication
    Modified residuei43 – 431Phosphoserine1 Publication

    Post-translational modificationi

    Phosphorylated at two positions (Ser-16 and Thr-42 or Ser-43), each 6-7%.1 Publication

    Keywords - PTMi

    Phosphoprotein

    Structurei

    3D structure databases

    ProteinModelPortaliP40625.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Contains 1 HMG box DNA-binding domain.PROSITE-ProRule annotation

    Family and domain databases

    Gene3Di1.10.30.10. 1 hit.
    InterProiIPR009071. HMG_box_dom.
    [Graphical view]
    PfamiPF00505. HMG_box. 1 hit.
    [Graphical view]
    SMARTiSM00398. HMG. 1 hit.
    [Graphical view]
    SUPFAMiSSF47095. SSF47095. 1 hit.
    PROSITEiPS50118. HMG_BOX_2. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    P40625-1 [UniParc]FASTAAdd to Basket

    « Hide

    GKVKDDKPAP PKRPLSAFFL FKQHNYDQVK KENPNAKITE LTSMIAEKWK   50
    HVTEKEKKKY EGLQQEAKAK YEKDMQAYEK KYGKPEKVKK IKKSKKGSK 99
    Length:99
    Mass (Da):11,627
    Last modified:February 1, 1995 - v1
    Checksum:i93BFB012A2D3D7FF
    GO

    Sequence databases

    PIRiJU0038.

    Cross-referencesi

    Sequence databases

    PIRi JU0038.

    3D structure databases

    ProteinModelPortali P40625.
    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Family and domain databases

    Gene3Di 1.10.30.10. 1 hit.
    InterProi IPR009071. HMG_box_dom.
    [Graphical view ]
    Pfami PF00505. HMG_box. 1 hit.
    [Graphical view ]
    SMARTi SM00398. HMG. 1 hit.
    [Graphical view ]
    SUPFAMi SSF47095. SSF47095. 1 hit.
    PROSITEi PS50118. HMG_BOX_2. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Tetrahymena HMG nonhistone chromosomal protein. Isolation and amino acid sequence lacking the N- and C-terminal domains of vertebrate HMG 1."
      Hayashi T., Hayashi H., Iwai K.
      J. Biochem. 105:577-581(1989) [PubMed] [Europe PMC] [Abstract]
      Cited for: PROTEIN SEQUENCE, PHOSPHORYLATION AT SER-16; THR-42 AND SER-43.
      Strain: GL.

    Entry informationi

    Entry nameiHMG_TETPY
    AccessioniPrimary (citable) accession number: P40625
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: February 1, 1995
    Last sequence update: February 1, 1995
    Last modified: October 1, 2014
    This is version 66 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)

    Miscellaneousi

    Keywords - Technical termi

    Direct protein sequencing

    Documents

    1. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3