Skip Header

You are using a version of Internet Explorer that may not display all features of this website. Please upgrade to a modern browser.
Contribute Send feedback
Read comments (?) or add your own

P40579 (YIV5_YEAST) Reviewed, UniProtKB/Swiss-Prot

Last modified February 19, 2014. Version 110. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (4) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Uncharacterized oxidoreductase YIR035C

EC=1.-.-.-
Gene names
Ordered Locus Names:YIR035C
OrganismSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) [Reference proteome]
Taxonomic identifier559292 [NCBI]
Taxonomic lineageEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces

Protein attributes

Sequence length254 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

General annotation (Comments)

Miscellaneous

Present with 2370 molecules/cell in log phase SD medium.

Sequence similarities

Belongs to the short-chain dehydrogenases/reductases (SDR) family.

Ontologies

Keywords
   Molecular functionOxidoreductase
   Technical term3D-structure
Complete proteome
Reference proteome
Gene Ontology (GO)
   Molecular_functionoxidoreductase activity

Inferred from electronic annotation. Source: UniProtKB-KW

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 254254Uncharacterized oxidoreductase YIR035C
PRO_0000054870

Regions

Nucleotide binding6 – 3025NAD or NADP By similarity

Sites

Active site1501Proton acceptor By similarity
Binding site1371Substrate By similarity

Secondary structure

......................................... 254
Helix Strand Turn

Details...

Sequences

Sequence LengthMass (Da)Tools
P40579 [UniParc].

Last modified February 1, 1995. Version 1.
Checksum: 916A5A460BE59F78

FASTA25427,481
        10         20         30         40         50         60 
MGKVILVTGV SRGIGKSIVD VLFSLDKDTV VYGVARSEAP LKKLKEKYGD RFFYVVGDIT 

        70         80         90        100        110        120 
EDSVLKQLVN AAVKGHGKID SLVANAGVLE PVQNVNEIDV NAWKKLYDIN FFSIVSLVGI 

       130        140        150        160        170        180 
ALPELKKTNG NVVFVSSDAC NMYFSSWGAY GSSKAALNHF AMTLANEERQ VKAIAVAPGI 

       190        200        210        220        230        240 
VDTDMQVNIR ENVGPSSMSA EQLKMFRGLK ENNQLLDSSV PATVYAKLAL HGIPDGVNGQ 

       250 
YLSYNDPALA DFMP 

« Hide

References

« Hide 'large scale' references
[1]"The nucleotide sequence of Saccharomyces cerevisiae chromosome IX."
Churcher C.M., Bowman S., Badcock K., Bankier A.T., Brown D., Chillingworth T., Connor R., Devlin K., Gentles S., Hamlin N., Harris D.E., Horsnell T., Hunt S., Jagels K., Jones M., Lye G., Moule S., Odell C. expand/collapse author list , Pearson D., Rajandream M.A., Rice P., Rowley N., Skelton J., Smith V., Walsh S.V., Whitehead S., Barrell B.G.
Nature 387:84-87(1997) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 204508 / S288c.
[2]Saccharomyces Genome Database
Submitted (DEC-2009) to the EMBL/GenBank/DDBJ databases
Cited for: GENOME REANNOTATION.
Strain: ATCC 204508 / S288c.
[3]"Approaching a complete repository of sequence-verified protein-encoding clones for Saccharomyces cerevisiae."
Hu Y., Rolfs A., Bhullar B., Murthy T.V.S., Zhu C., Berger M.F., Camargo A.A., Kelley F., McCarron S., Jepson D., Richardson A., Raphael J., Moreira D., Taycher E., Zuo D., Mohr S., Kane M.F., Williamson J. expand/collapse author list , Simpson A.J.G., Bulyk M.L., Harlow E., Marsischky G., Kolodner R.D., LaBaer J.
Genome Res. 17:536-543(2007) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
Strain: ATCC 204508 / S288c.
[4]"Global analysis of protein expression in yeast."
Ghaemmaghami S., Huh W.-K., Bower K., Howson R.W., Belle A., Dephoure N., O'Shea E.K., Weissman J.S.
Nature 425:737-741(2003) [PubMed] [Europe PMC] [Abstract]
Cited for: LEVEL OF PROTEIN EXPRESSION [LARGE SCALE ANALYSIS].
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
Z38061 Genomic DNA. Translation: CAA86195.1.
AY692591 Genomic DNA. Translation: AAT92610.1.
BK006942 Genomic DNA. Translation: DAA08582.1.
PIRS48497.
RefSeqNP_012301.3. NM_001179557.3.

3D structure databases

PDBe
RCSB PDB
PDBj
EntryMethodResolution (Å)ChainPositionsPDBsum
3KZVX-ray2.00A1-254[»]
ProteinModelPortalP40579.
SMRP40579. Positions 2-254.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

BioGrid35026. 15 interactions.
DIPDIP-4612N.
IntActP40579. 3 interactions.
MINTMINT-492719.
STRING4932.YIR035C.

Proteomic databases

PaxDbP40579.
PeptideAtlasP40579.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblFungiYIR035C; YIR035C; YIR035C.
GeneID854853.
KEGGsce:YIR035C.

Organism-specific databases

CYGDYIR035c.
SGDS000001474. YIR035C.

Phylogenomic databases

eggNOGCOG1028.
GeneTreeENSGT00440000033609.
KOK00540.
OMAQVQFIAG.
OrthoDBEOG72C59W.

Enzyme and pathway databases

BioCycYEAST:G3O-31449-MONOMER.

Gene expression databases

GenevestigatorP40579.

Family and domain databases

Gene3D3.40.50.720. 1 hit.
InterProIPR002198. DH_sc/Rdtase_SDR.
IPR002347. Glc/ribitol_DH.
IPR016040. NAD(P)-bd_dom.
IPR020904. Sc_DH/Rdtase_CS.
[Graphical view]
PfamPF00106. adh_short. 1 hit.
[Graphical view]
PRINTSPR00081. GDHRDH.
PR00080. SDRFAMILY.
PROSITEPS00061. ADH_SHORT. 1 hit.
[Graphical view]
ProtoNetSearch...

Other

EvolutionaryTraceP40579.
NextBio977758.
PROP40579.

Entry information

Entry nameYIV5_YEAST
AccessionPrimary (citable) accession number: P40579
Secondary accession number(s): D6VVW6
Entry history
Integrated into UniProtKB/Swiss-Prot: February 1, 1995
Last sequence update: February 1, 1995
Last modified: February 19, 2014
This is version 110 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Relevant documents

Yeast chromosome IX

Yeast (Saccharomyces cerevisiae) chromosome IX: entries and gene names

Yeast

Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD

SIMILARITY comments

Index of protein domains and families

PDB cross-references

Index of Protein Data Bank (PDB) cross-references