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P40579

- YIV5_YEAST

UniProt

P40579 - YIV5_YEAST

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Protein

Uncharacterized oxidoreductase YIR035C

Gene

YIR035C

Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed - Annotation score: 2 out of 5- Experimental evidence at protein leveli

Functioni

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei137 – 1371SubstrateBy similarity
Active sitei150 – 1501Proton acceptorPROSITE-ProRule annotation

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi6 – 3025NAD or NADPBy similarityAdd
BLAST

GO - Molecular functioni

  1. oxidoreductase activity Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

Oxidoreductase

Enzyme and pathway databases

BioCyciYEAST:G3O-31449-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Uncharacterized oxidoreductase YIR035C (EC:1.-.-.-)
Gene namesi
Ordered Locus Names:YIR035C
OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Taxonomic identifieri559292 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
ProteomesiUP000002311: Chromosome IX

Organism-specific databases

CYGDiYIR035c.
SGDiS000001474. YIR035C.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 254254Uncharacterized oxidoreductase YIR035CPRO_0000054870Add
BLAST

Proteomic databases

MaxQBiP40579.
PaxDbiP40579.
PeptideAtlasiP40579.

Expressioni

Gene expression databases

GenevestigatoriP40579.

Interactioni

Protein-protein interaction databases

BioGridi35026. 16 interactions.
DIPiDIP-4612N.
IntActiP40579. 3 interactions.
MINTiMINT-492719.
STRINGi4932.YIR035C.

Structurei

Secondary structure

1
254
Legend: HelixTurnBeta strand
Show more details
Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Beta strandi4 – 74
Helixi13 – 2513
Beta strandi30 – 367
Helixi38 – 4811
Helixi49 – 513
Beta strandi52 – 576
Helixi62 – 7615
Beta strandi81 – 855
Turni93 – 964
Helixi100 – 11011
Helixi112 – 12817
Beta strandi131 – 1355
Helixi148 – 1558
Helixi157 – 16711
Beta strandi171 – 1777
Turni195 – 1973
Helixi200 – 21011
Helixi219 – 23113
Helixi235 – 2373
Beta strandi241 – 2433
Helixi247 – 2526

3D structure databases

Select the link destinations:
PDBe
RCSB PDB
PDBj
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
3KZVX-ray2.00A1-254[»]
ProteinModelPortaliP40579.
SMRiP40579. Positions 2-254.
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiP40579.

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiCOG1028.
GeneTreeiENSGT00440000033609.
InParanoidiP40579.
KOiK00540.
OMAiQVQFIAG.
OrthoDBiEOG72C59W.

Family and domain databases

Gene3Di3.40.50.720. 1 hit.
InterProiIPR002198. DH_sc/Rdtase_SDR.
IPR002347. Glc/ribitol_DH.
IPR016040. NAD(P)-bd_dom.
IPR020904. Sc_DH/Rdtase_CS.
[Graphical view]
PfamiPF00106. adh_short. 1 hit.
[Graphical view]
PRINTSiPR00081. GDHRDH.
PR00080. SDRFAMILY.
PROSITEiPS00061. ADH_SHORT. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P40579-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MGKVILVTGV SRGIGKSIVD VLFSLDKDTV VYGVARSEAP LKKLKEKYGD
60 70 80 90 100
RFFYVVGDIT EDSVLKQLVN AAVKGHGKID SLVANAGVLE PVQNVNEIDV
110 120 130 140 150
NAWKKLYDIN FFSIVSLVGI ALPELKKTNG NVVFVSSDAC NMYFSSWGAY
160 170 180 190 200
GSSKAALNHF AMTLANEERQ VKAIAVAPGI VDTDMQVNIR ENVGPSSMSA
210 220 230 240 250
EQLKMFRGLK ENNQLLDSSV PATVYAKLAL HGIPDGVNGQ YLSYNDPALA

DFMP
Length:254
Mass (Da):27,481
Last modified:February 1, 1995 - v1
Checksum:i916A5A460BE59F78
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
Z38061 Genomic DNA. Translation: CAA86195.1.
AY692591 Genomic DNA. Translation: AAT92610.1.
BK006942 Genomic DNA. Translation: DAA08582.1.
PIRiS48497.
RefSeqiNP_012301.3. NM_001179557.3.

Genome annotation databases

EnsemblFungiiYIR035C; YIR035C; YIR035C.
GeneIDi854853.
KEGGisce:YIR035C.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
Z38061 Genomic DNA. Translation: CAA86195.1 .
AY692591 Genomic DNA. Translation: AAT92610.1 .
BK006942 Genomic DNA. Translation: DAA08582.1 .
PIRi S48497.
RefSeqi NP_012301.3. NM_001179557.3.

3D structure databases

Select the link destinations:
PDBe
RCSB PDB
PDBj
Links Updated
Entry Method Resolution (Å) Chain Positions PDBsum
3KZV X-ray 2.00 A 1-254 [» ]
ProteinModelPortali P40579.
SMRi P40579. Positions 2-254.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

BioGridi 35026. 16 interactions.
DIPi DIP-4612N.
IntActi P40579. 3 interactions.
MINTi MINT-492719.
STRINGi 4932.YIR035C.

Proteomic databases

MaxQBi P40579.
PaxDbi P40579.
PeptideAtlasi P40579.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblFungii YIR035C ; YIR035C ; YIR035C .
GeneIDi 854853.
KEGGi sce:YIR035C.

Organism-specific databases

CYGDi YIR035c.
SGDi S000001474. YIR035C.

Phylogenomic databases

eggNOGi COG1028.
GeneTreei ENSGT00440000033609.
InParanoidi P40579.
KOi K00540.
OMAi QVQFIAG.
OrthoDBi EOG72C59W.

Enzyme and pathway databases

BioCyci YEAST:G3O-31449-MONOMER.

Miscellaneous databases

EvolutionaryTracei P40579.
NextBioi 977758.
PROi P40579.

Gene expression databases

Genevestigatori P40579.

Family and domain databases

Gene3Di 3.40.50.720. 1 hit.
InterProi IPR002198. DH_sc/Rdtase_SDR.
IPR002347. Glc/ribitol_DH.
IPR016040. NAD(P)-bd_dom.
IPR020904. Sc_DH/Rdtase_CS.
[Graphical view ]
Pfami PF00106. adh_short. 1 hit.
[Graphical view ]
PRINTSi PR00081. GDHRDH.
PR00080. SDRFAMILY.
PROSITEi PS00061. ADH_SHORT. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 204508 / S288c.
  2. Cited for: GENOME REANNOTATION.
    Strain: ATCC 204508 / S288c.
  3. Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
    Strain: ATCC 204508 / S288c.
  4. Cited for: LEVEL OF PROTEIN EXPRESSION [LARGE SCALE ANALYSIS].

Entry informationi

Entry nameiYIV5_YEAST
AccessioniPrimary (citable) accession number: P40579
Secondary accession number(s): D6VVW6
Entry historyi
Integrated into UniProtKB/Swiss-Prot: February 1, 1995
Last sequence update: February 1, 1995
Last modified: October 29, 2014
This is version 113 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Miscellaneous

Present with 2370 molecules/cell in log phase SD medium.1 Publication

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome

Documents

  1. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  2. SIMILARITY comments
    Index of protein domains and families
  3. Yeast
    Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD
  4. Yeast chromosome IX
    Yeast (Saccharomyces cerevisiae) chromosome IX: entries and gene names

External Data

Dasty 3