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Protein

Uncharacterized oxidoreductase YIR035C

Gene

YIR035C

Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei137 – 1371SubstrateBy similarity
Active sitei150 – 1501Proton acceptorPROSITE-ProRule annotation

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi6 – 3025NAD or NADPBy similarityAdd
BLAST

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

Oxidoreductase

Enzyme and pathway databases

BioCyciYEAST:G3O-31449-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Uncharacterized oxidoreductase YIR035C (EC:1.-.-.-)
Gene namesi
Ordered Locus Names:YIR035C
OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Taxonomic identifieri559292 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
ProteomesiUP000002311 Componenti: Chromosome IX

Organism-specific databases

CYGDiYIR035c.
EuPathDBiFungiDB:YIR035C.
SGDiS000001474. YIR035C.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 254254Uncharacterized oxidoreductase YIR035CPRO_0000054870Add
BLAST

Proteomic databases

MaxQBiP40579.
PaxDbiP40579.
PeptideAtlasiP40579.

Interactioni

Protein-protein interaction databases

BioGridi35026. 16 interactions.
DIPiDIP-4612N.
IntActiP40579. 3 interactions.
MINTiMINT-492719.
STRINGi4932.YIR035C.

Structurei

Secondary structure

1
254
Legend: HelixTurnBeta strand
Show more details
Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Beta strandi4 – 74Combined sources
Helixi13 – 2513Combined sources
Beta strandi30 – 367Combined sources
Helixi38 – 4811Combined sources
Helixi49 – 513Combined sources
Beta strandi52 – 576Combined sources
Helixi62 – 7615Combined sources
Beta strandi81 – 855Combined sources
Turni93 – 964Combined sources
Helixi100 – 11011Combined sources
Helixi112 – 12817Combined sources
Beta strandi131 – 1355Combined sources
Helixi148 – 1558Combined sources
Helixi157 – 16711Combined sources
Beta strandi171 – 1777Combined sources
Turni195 – 1973Combined sources
Helixi200 – 21011Combined sources
Helixi219 – 23113Combined sources
Helixi235 – 2373Combined sources
Beta strandi241 – 2433Combined sources
Helixi247 – 2526Combined sources

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
3KZVX-ray2.00A1-254[»]
ProteinModelPortaliP40579.
SMRiP40579. Positions 2-254.
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiP40579.

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiCOG1028.
GeneTreeiENSGT00440000033609.
InParanoidiP40579.
KOiK00540.
OMAiAPEVACF.
OrthoDBiEOG72C59W.

Family and domain databases

Gene3Di3.40.50.720. 1 hit.
InterProiIPR002198. DH_sc/Rdtase_SDR.
IPR002347. Glc/ribitol_DH.
IPR016040. NAD(P)-bd_dom.
IPR020904. Sc_DH/Rdtase_CS.
[Graphical view]
PfamiPF00106. adh_short. 1 hit.
[Graphical view]
PRINTSiPR00081. GDHRDH.
PR00080. SDRFAMILY.
PROSITEiPS00061. ADH_SHORT. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P40579-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGKVILVTGV SRGIGKSIVD VLFSLDKDTV VYGVARSEAP LKKLKEKYGD
60 70 80 90 100
RFFYVVGDIT EDSVLKQLVN AAVKGHGKID SLVANAGVLE PVQNVNEIDV
110 120 130 140 150
NAWKKLYDIN FFSIVSLVGI ALPELKKTNG NVVFVSSDAC NMYFSSWGAY
160 170 180 190 200
GSSKAALNHF AMTLANEERQ VKAIAVAPGI VDTDMQVNIR ENVGPSSMSA
210 220 230 240 250
EQLKMFRGLK ENNQLLDSSV PATVYAKLAL HGIPDGVNGQ YLSYNDPALA

DFMP
Length:254
Mass (Da):27,481
Last modified:February 1, 1995 - v1
Checksum:i916A5A460BE59F78
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Z38061 Genomic DNA. Translation: CAA86195.1.
AY692591 Genomic DNA. Translation: AAT92610.1.
BK006942 Genomic DNA. Translation: DAA08582.1.
PIRiS48497.
RefSeqiNP_012301.3. NM_001179557.3.

Genome annotation databases

EnsemblFungiiYIR035C; YIR035C; YIR035C.
GeneIDi854853.
KEGGisce:YIR035C.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Z38061 Genomic DNA. Translation: CAA86195.1.
AY692591 Genomic DNA. Translation: AAT92610.1.
BK006942 Genomic DNA. Translation: DAA08582.1.
PIRiS48497.
RefSeqiNP_012301.3. NM_001179557.3.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
3KZVX-ray2.00A1-254[»]
ProteinModelPortaliP40579.
SMRiP40579. Positions 2-254.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi35026. 16 interactions.
DIPiDIP-4612N.
IntActiP40579. 3 interactions.
MINTiMINT-492719.
STRINGi4932.YIR035C.

Proteomic databases

MaxQBiP40579.
PaxDbiP40579.
PeptideAtlasiP40579.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblFungiiYIR035C; YIR035C; YIR035C.
GeneIDi854853.
KEGGisce:YIR035C.

Organism-specific databases

CYGDiYIR035c.
EuPathDBiFungiDB:YIR035C.
SGDiS000001474. YIR035C.

Phylogenomic databases

eggNOGiCOG1028.
GeneTreeiENSGT00440000033609.
InParanoidiP40579.
KOiK00540.
OMAiAPEVACF.
OrthoDBiEOG72C59W.

Enzyme and pathway databases

BioCyciYEAST:G3O-31449-MONOMER.

Miscellaneous databases

EvolutionaryTraceiP40579.
NextBioi977758.
PROiP40579.

Family and domain databases

Gene3Di3.40.50.720. 1 hit.
InterProiIPR002198. DH_sc/Rdtase_SDR.
IPR002347. Glc/ribitol_DH.
IPR016040. NAD(P)-bd_dom.
IPR020904. Sc_DH/Rdtase_CS.
[Graphical view]
PfamiPF00106. adh_short. 1 hit.
[Graphical view]
PRINTSiPR00081. GDHRDH.
PR00080. SDRFAMILY.
PROSITEiPS00061. ADH_SHORT. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 204508 / S288c.
  2. Cited for: GENOME REANNOTATION.
    Strain: ATCC 204508 / S288c.
  3. Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
    Strain: ATCC 204508 / S288c.
  4. Cited for: LEVEL OF PROTEIN EXPRESSION [LARGE SCALE ANALYSIS].

Entry informationi

Entry nameiYIV5_YEAST
AccessioniPrimary (citable) accession number: P40579
Secondary accession number(s): D6VVW6
Entry historyi
Integrated into UniProtKB/Swiss-Prot: February 1, 1995
Last sequence update: February 1, 1995
Last modified: June 24, 2015
This is version 117 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Miscellaneous

Present with 2370 molecules/cell in log phase SD medium.1 Publication

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome

Documents

  1. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  2. SIMILARITY comments
    Index of protein domains and families
  3. Yeast
    Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD
  4. Yeast chromosome IX
    Yeast (Saccharomyces cerevisiae) chromosome IX: entries and gene names

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.