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P40579

- YIV5_YEAST

UniProt

P40579 - YIV5_YEAST

Protein

Uncharacterized oxidoreductase YIR035C

Gene

YIR035C

Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed - Annotation score: 2 out of 5- Experimental evidence at protein leveli
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    • History
      Entry version 112 (01 Oct 2014)
      Sequence version 1 (01 Feb 1995)
      Previous versions | rss
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    Functioni

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Binding sitei137 – 1371SubstrateBy similarity
    Active sitei150 – 1501Proton acceptorPROSITE-ProRule annotation

    Regions

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Nucleotide bindingi6 – 3025NAD or NADPBy similarityAdd
    BLAST

    GO - Molecular functioni

    1. oxidoreductase activity Source: UniProtKB-KW

    Keywords - Molecular functioni

    Oxidoreductase

    Enzyme and pathway databases

    BioCyciYEAST:G3O-31449-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Uncharacterized oxidoreductase YIR035C (EC:1.-.-.-)
    Gene namesi
    Ordered Locus Names:YIR035C
    OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
    Taxonomic identifieri559292 [NCBI]
    Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
    ProteomesiUP000002311: Chromosome IX

    Organism-specific databases

    CYGDiYIR035c.
    SGDiS000001474. YIR035C.

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 254254Uncharacterized oxidoreductase YIR035CPRO_0000054870Add
    BLAST

    Proteomic databases

    MaxQBiP40579.
    PaxDbiP40579.
    PeptideAtlasiP40579.

    Expressioni

    Gene expression databases

    GenevestigatoriP40579.

    Interactioni

    Protein-protein interaction databases

    BioGridi35026. 15 interactions.
    DIPiDIP-4612N.
    IntActiP40579. 3 interactions.
    MINTiMINT-492719.
    STRINGi4932.YIR035C.

    Structurei

    Secondary structure

    1
    254
    Legend: HelixTurnBeta strand
    Show more details
    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Beta strandi4 – 74
    Helixi13 – 2513
    Beta strandi30 – 367
    Helixi38 – 4811
    Helixi49 – 513
    Beta strandi52 – 576
    Helixi62 – 7615
    Beta strandi81 – 855
    Turni93 – 964
    Helixi100 – 11011
    Helixi112 – 12817
    Beta strandi131 – 1355
    Helixi148 – 1558
    Helixi157 – 16711
    Beta strandi171 – 1777
    Turni195 – 1973
    Helixi200 – 21011
    Helixi219 – 23113
    Helixi235 – 2373
    Beta strandi241 – 2433
    Helixi247 – 2526

    3D structure databases

    Select the link destinations:
    PDBe
    RCSB PDB
    PDBj
    Links Updated
    EntryMethodResolution (Å)ChainPositionsPDBsum
    3KZVX-ray2.00A1-254[»]
    ProteinModelPortaliP40579.
    SMRiP40579. Positions 2-254.
    ModBaseiSearch...
    MobiDBiSearch...

    Miscellaneous databases

    EvolutionaryTraceiP40579.

    Family & Domainsi

    Sequence similaritiesi

    Phylogenomic databases

    eggNOGiCOG1028.
    GeneTreeiENSGT00440000033609.
    KOiK00540.
    OMAiQVQFIAG.
    OrthoDBiEOG72C59W.

    Family and domain databases

    Gene3Di3.40.50.720. 1 hit.
    InterProiIPR002198. DH_sc/Rdtase_SDR.
    IPR002347. Glc/ribitol_DH.
    IPR016040. NAD(P)-bd_dom.
    IPR020904. Sc_DH/Rdtase_CS.
    [Graphical view]
    PfamiPF00106. adh_short. 1 hit.
    [Graphical view]
    PRINTSiPR00081. GDHRDH.
    PR00080. SDRFAMILY.
    PROSITEiPS00061. ADH_SHORT. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    P40579-1 [UniParc]FASTAAdd to Basket

    « Hide

    MGKVILVTGV SRGIGKSIVD VLFSLDKDTV VYGVARSEAP LKKLKEKYGD    50
    RFFYVVGDIT EDSVLKQLVN AAVKGHGKID SLVANAGVLE PVQNVNEIDV 100
    NAWKKLYDIN FFSIVSLVGI ALPELKKTNG NVVFVSSDAC NMYFSSWGAY 150
    GSSKAALNHF AMTLANEERQ VKAIAVAPGI VDTDMQVNIR ENVGPSSMSA 200
    EQLKMFRGLK ENNQLLDSSV PATVYAKLAL HGIPDGVNGQ YLSYNDPALA 250
    DFMP 254
    Length:254
    Mass (Da):27,481
    Last modified:February 1, 1995 - v1
    Checksum:i916A5A460BE59F78
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    Z38061 Genomic DNA. Translation: CAA86195.1.
    AY692591 Genomic DNA. Translation: AAT92610.1.
    BK006942 Genomic DNA. Translation: DAA08582.1.
    PIRiS48497.
    RefSeqiNP_012301.3. NM_001179557.3.

    Genome annotation databases

    EnsemblFungiiYIR035C; YIR035C; YIR035C.
    GeneIDi854853.
    KEGGisce:YIR035C.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    Z38061 Genomic DNA. Translation: CAA86195.1 .
    AY692591 Genomic DNA. Translation: AAT92610.1 .
    BK006942 Genomic DNA. Translation: DAA08582.1 .
    PIRi S48497.
    RefSeqi NP_012301.3. NM_001179557.3.

    3D structure databases

    Select the link destinations:
    PDBe
    RCSB PDB
    PDBj
    Links Updated
    Entry Method Resolution (Å) Chain Positions PDBsum
    3KZV X-ray 2.00 A 1-254 [» ]
    ProteinModelPortali P40579.
    SMRi P40579. Positions 2-254.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    BioGridi 35026. 15 interactions.
    DIPi DIP-4612N.
    IntActi P40579. 3 interactions.
    MINTi MINT-492719.
    STRINGi 4932.YIR035C.

    Proteomic databases

    MaxQBi P40579.
    PaxDbi P40579.
    PeptideAtlasi P40579.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblFungii YIR035C ; YIR035C ; YIR035C .
    GeneIDi 854853.
    KEGGi sce:YIR035C.

    Organism-specific databases

    CYGDi YIR035c.
    SGDi S000001474. YIR035C.

    Phylogenomic databases

    eggNOGi COG1028.
    GeneTreei ENSGT00440000033609.
    KOi K00540.
    OMAi QVQFIAG.
    OrthoDBi EOG72C59W.

    Enzyme and pathway databases

    BioCyci YEAST:G3O-31449-MONOMER.

    Miscellaneous databases

    EvolutionaryTracei P40579.
    NextBioi 977758.
    PROi P40579.

    Gene expression databases

    Genevestigatori P40579.

    Family and domain databases

    Gene3Di 3.40.50.720. 1 hit.
    InterProi IPR002198. DH_sc/Rdtase_SDR.
    IPR002347. Glc/ribitol_DH.
    IPR016040. NAD(P)-bd_dom.
    IPR020904. Sc_DH/Rdtase_CS.
    [Graphical view ]
    Pfami PF00106. adh_short. 1 hit.
    [Graphical view ]
    PRINTSi PR00081. GDHRDH.
    PR00080. SDRFAMILY.
    PROSITEi PS00061. ADH_SHORT. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC 204508 / S288c.
    2. Cited for: GENOME REANNOTATION.
      Strain: ATCC 204508 / S288c.
    3. Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
      Strain: ATCC 204508 / S288c.
    4. Cited for: LEVEL OF PROTEIN EXPRESSION [LARGE SCALE ANALYSIS].

    Entry informationi

    Entry nameiYIV5_YEAST
    AccessioniPrimary (citable) accession number: P40579
    Secondary accession number(s): D6VVW6
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: February 1, 1995
    Last sequence update: February 1, 1995
    Last modified: October 1, 2014
    This is version 112 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programFungal Protein Annotation Program

    Miscellaneousi

    Miscellaneous

    Present with 2370 molecules/cell in log phase SD medium.1 Publication

    Keywords - Technical termi

    3D-structure, Complete proteome, Reference proteome

    Documents

    1. PDB cross-references
      Index of Protein Data Bank (PDB) cross-references
    2. SIMILARITY comments
      Index of protein domains and families
    3. Yeast
      Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD
    4. Yeast chromosome IX
      Yeast (Saccharomyces cerevisiae) chromosome IX: entries and gene names

    External Data

    Dasty 3