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Protein

Protein MGA2

Gene

MGA2

Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed-Annotation score: Annotation score: 4 out of 5-Experimental evidence at protein leveli

Functioni

Miscellaneous

Present with 300 molecules/cell in log phase SD medium.1 Publication

GO - Biological processi

  • cellular response to cold Source: SGD
  • chromatin silencing at silent mating-type cassette Source: SGD
  • mRNA stabilization Source: SGD
  • positive regulation of transcription from RNA polymerase II promoter Source: SGD
  • positive regulation of transcription from RNA polymerase II promoter in response to cobalt ion Source: SGD
  • positive regulation of transcription from RNA polymerase II promoter in response to hypoxia Source: SGD
  • positive regulation of unsaturated fatty acid biosynthetic process by positive regulation of transcription from RNA polymerase II promoter Source: SGD

Enzyme and pathway databases

BioCyciYEAST:G3O-31448-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Protein MGA2
Gene namesi
Name:MGA2
Ordered Locus Names:YIR033W
OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Taxonomic identifieri559292 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
Proteomesi
  • UP000002311 Componenti: Chromosome IX

Organism-specific databases

EuPathDBiFungiDB:YIR033W.
SGDiS000001472. MGA2.

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei1037 – 1054HelicalSequence analysisAdd BLAST18

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000670741 – 1113Protein MGA2Add BLAST1113

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei255PhosphoserineCombined sources1
Modified residuei467PhosphoserineCombined sources1

Keywords - PTMi

Phosphoprotein

Proteomic databases

MaxQBiP40578.
PRIDEiP40578.

PTM databases

iPTMnetiP40578.

Interactioni

Protein-protein interaction databases

BioGridi35024. 508 interactors.
DIPiDIP-6689N.
IntActiP40578. 21 interactors.
MINTiMINT-655593.
STRINGi4932.YIR033W.

Structurei

3D structure databases

ProteinModelPortaliP40578.
SMRiP40578.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini530 – 610IPT/TIGAdd BLAST81
Repeati719 – 748ANK 1Add BLAST30
Repeati752 – 781ANK 2Add BLAST30

Keywords - Domaini

ANK repeat, Repeat, Transmembrane, Transmembrane helix

Phylogenomic databases

GeneTreeiENSGT00530000067551.
HOGENOMiHOG000113576.
InParanoidiP40578.
KOiK06867.
OMAiQGPINGG.
OrthoDBiEOG092C06NJ.

Family and domain databases

CDDicd00204. ANK. 1 hit.
Gene3Di1.25.40.20. 1 hit.
2.60.40.10. 1 hit.
InterProiView protein in InterPro
IPR002110. Ankyrin_rpt.
IPR020683. Ankyrin_rpt-contain_dom.
IPR036770. Ankyrin_rpt-contain_sf.
IPR013783. Ig-like_fold.
IPR014756. Ig_E-set.
IPR002909. IPT.
PfamiView protein in Pfam
PF12796. Ank_2. 1 hit.
PF01833. TIG. 1 hit.
SMARTiView protein in SMART
SM00248. ANK. 2 hits.
SM00429. IPT. 1 hit.
SUPFAMiSSF48403. SSF48403. 1 hit.
SSF81296. SSF81296. 1 hit.
PROSITEiView protein in PROSITE
PS50297. ANK_REP_REGION. 1 hit.
PS50088. ANK_REPEAT. 2 hits.

Sequencei

Sequence statusi: Complete.

P40578-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MQQNSEFLTE TPGSDPHISQ LHANSVMESQ LLDDFLLNGS PMYQDDSMAH
60 70 80 90 100
INIDEGANFQ NFIKTDEGDS PNLLSFEGIG NNTHVNQNVS TPLEEEMESN
110 120 130 140 150
RALKEEEEDE HENKVFNEKN IGNPAHDEIV FGRKETIQSV YINPLDYLKV
160 170 180 190 200
NAAQLPLDVE VSGLPQVSRV ENQLKLKVKI TSETPLNQSM LYLPSDSISR
210 220 230 240 250
EKFYLKKNIE DFSEDFKKNL LYINAFVLCA VSNRTTNVCT KCVKREQRRA
260 270 280 290 300
ARRKSGIADN LLWCNNINRR LVVFNNKQVF PIMKTFDNVK EFELTTRLVC
310 320 330 340 350
YCRHHKANNG FVILFTITDW QNRLLGKFTT TPIMITDRKP ANMDTTKFNN
360 370 380 390 400
TTTSSRRQLT EEESTTEYYS TDNNQLSKDE NMPFQYTYQH NPYDNDSQMN
410 420 430 440 450
NIPLKDKNVP FPYSISQQTD LLQNNNLSLN LSLPNQHIPS PTSMSEEGSE
460 470 480 490 500
SFNYHHRDND NPVRTISLTN IEQQSQLNQR KRARNNLEND IGKPLFKHSF
510 520 530 540 550
SNSISATNTM NPALHSMQDF SMKNNNNNLP SINRVIPSQG PINGGIEVTL
560 570 580 590 600
LGCNFKDGLS VKFGSNLALS TQCWSETTIV TYLPPAAYAG QVFVSITDTN
610 620 630 640 650
NENNNDDLPQ EIEINDNKKA IFTYVDDTDR QLIELALQIV GLKMNGKLED
660 670 680 690 700
ARNIAKRIVG NDSPDSGTNG NSCSKSTGPS PNQHSMNLNT SVLYSDEVLI
710 720 730 740 750
QKVIKSLNIN SNISICDSLG RTLLHLACLK NYSSLVYTLI KKGARVNDID
760 770 780 790 800
SFGLTPLHFA CISGDPKIIK MLLNCKVNYS LRSHNGLTAR EVFIANHIHS
810 820 830 840 850
KEIDKKQDNR DNHKFVHNDT YISEVLSLFE EFQNGTKFTD SVETDSNYSI
860 870 880 890 900
SRKYSQSSFN SSLLDNESLN ENLFESQSMI NPTSMEIQHP TLQLFENSSY
910 920 930 940 950
SEYDQSDFEE DGDEDLFVTD EVEKPGVACR EEQSELLDIG SSANEPEEDN
960 970 980 990 1000
GSTSLWNRVL HRINDDLPKY EDLFPLSWGK DDKLKTTNQD SIVEQSASNI
1010 1020 1030 1040 1050
ENSENSEEED YEEEEEFLKK QFNRFFQNKQ NFRNDKMLIF FWIPLTLLLL
1060 1070 1080 1090 1100
TWFIMYKFGN QDSSINHISE LISEYLRIAL AKFLLGNERM KTAFRSKLSN
1110
LQTTRMLNDL IVS
Length:1,113
Mass (Da):127,055
Last modified:February 1, 1995 - v1
Checksum:iEC8A6D46C01CF917
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Z38061 Genomic DNA. Translation: CAA86193.1.
BK006942 Genomic DNA. Translation: DAA08580.1.
PIRiS48495.
RefSeqiNP_012299.1. NM_001179555.1.

Genome annotation databases

EnsemblFungiiYIR033W; YIR033W; YIR033W.
GeneIDi854851.
KEGGisce:YIR033W.

Similar proteinsi

Entry informationi

Entry nameiMGA2_YEAST
AccessioniPrimary (citable) accession number: P40578
Secondary accession number(s): D6VVW4
Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 1, 1995
Last sequence update: February 1, 1995
Last modified: November 22, 2017
This is version 143 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Yeast
    Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD
  2. Yeast chromosome IX
    Yeast (Saccharomyces cerevisiae) chromosome IX: entries and gene names