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Protein

DnaJ-like protein 1

Gene

DJP1

Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Required for peroxisomal protein import which maintains the function of peroxisomes.2 Publications

Miscellaneous

Present with 8970 molecules/cell in log phase SD medium.1 Publication

GO - Molecular functioni

  • chaperone binding Source: SGD

GO - Biological processi

  • protein import into mitochondrial outer membrane Source: SGD
  • protein import into peroxisome matrix Source: SGD

Keywordsi

Molecular functionChaperone

Enzyme and pathway databases

BioCyciYEAST:G3O-31425-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
DnaJ-like protein 1
Alternative name(s):
Peroxisome assembly protein 22
Gene namesi
Name:DJP1
Synonyms:ICS1, PAS22
Ordered Locus Names:YIR004W
ORF Names:YIB4W
OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Taxonomic identifieri559292 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
Proteomesi
  • UP000002311 Componenti: Chromosome IX

Organism-specific databases

EuPathDBiFungiDB:YIR004W
SGDiS000001443 DJP1

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000711411 – 432DnaJ-like protein 1Add BLAST432

Proteomic databases

MaxQBiP40564
PaxDbiP40564
PRIDEiP40564

2D gel databases

UCD-2DPAGEiP40564

PTM databases

iPTMnetiP40564

Interactioni

Subunit structurei

Interacts with SLN1.1 Publication

Binary interactionsi

WithEntry#Exp.IntActNotes
SSA2P105922EBI-25380,EBI-8603

GO - Molecular functioni

  • chaperone binding Source: SGD

Protein-protein interaction databases

BioGridi34995, 52 interactors
DIPiDIP-5923N
IntActiP40564, 185 interactors
STRINGi4932.YIR004W

Structurei

3D structure databases

ProteinModelPortaliP40564
SMRiP40564
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini4 – 73JPROSITE-ProRule annotationAdd BLAST70

Sequence similaritiesi

Belongs to the DnaJ family.Curated

Phylogenomic databases

GeneTreeiENSGT00550000074688
HOGENOMiHOG000186929
InParanoidiP40564
OMAiDWTDEKK
OrthoDBiEOG092C4Z2R

Family and domain databases

CDDicd06257 DnaJ, 1 hit
Gene3Di1.10.287.110, 1 hit
InterProiView protein in InterPro
IPR001623 DnaJ_domain
IPR018253 DnaJ_domain_CS
IPR026894 DnaJ_X
IPR036869 J_dom_sf
PfamiView protein in Pfam
PF00226 DnaJ, 1 hit
PF14308 DnaJ-X, 1 hit
PRINTSiPR00625 JDOMAIN
SMARTiView protein in SMART
SM00271 DnaJ, 1 hit
SUPFAMiSSF46565 SSF46565, 1 hit
PROSITEiView protein in PROSITE
PS00636 DNAJ_1, 1 hit
PS50076 DNAJ_2, 1 hit

Sequencei

Sequence statusi: Complete.

P40564-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MVVDTEYYDL LGVSTTASSI EIKKAYRKKS IQEHPDKNPN DPTATERFQA
60 70 80 90 100
ISEAYQVLGD DDLRAKYDKY GRKEAIPQGG FEDAAEQFSV IFGGDAFASY
110 120 130 140 150
IGELMLLKNL QKTEELNAED EAEKEKENVE TMEESPADGK TNGTTNAVDA
160 170 180 190 200
ALGNTNEKDD KNKARTTSGN LTVHDGNKKN EQVGAEAKKK KTKLEQFEEE
210 220 230 240 250
QEVEKQKRVD QLSKTLIERL SILTESVYDD ACKDSFKKKF EEEANLLKME
260 270 280 290 300
SFGLDILHTI GDVYYEKAEI FLASQNLFGM GGIFHSMKAK GGVFMDTLRT
310 320 330 340 350
VSAAIDAQNT MKELEKMKEA STNNEPLFDK DGNEQIKPTT EELAQQEQLL
360 370 380 390 400
MGKVLSAAWH GSKYEITSTL RGVCKKVLED DSVSKKTLIR RAEAMKLLGE
410 420 430
VFKKTFRTKV EQEEAQIFEE LVAEATKKKR HT
Length:432
Mass (Da):48,575
Last modified:February 1, 1995 - v1
Checksum:i8127D6886BC78B96
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti325E → G in AAS56212 (PubMed:17322287).Curated1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X79743 Genomic DNA No translation available.
Z38062 Genomic DNA Translation: CAA86206.1
AY557886 Genomic DNA Translation: AAS56212.1
BK006942 Genomic DNA Translation: DAA08550.1
PIRiS48438
RefSeqiNP_012269.1, NM_001179526.1

Genome annotation databases

EnsemblFungiiYIR004W; YIR004W; YIR004W
GeneIDi854820
KEGGisce:YIR004W

Similar proteinsi

Entry informationi

Entry nameiDJP1_YEAST
AccessioniPrimary (citable) accession number: P40564
Secondary accession number(s): D6VVT4, Q6Q5N6
Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 1, 1995
Last sequence update: February 1, 1995
Last modified: March 28, 2018
This is version 137 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome
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Main funding by: National Institutes of Health