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Protein

Pheromone-regulated membrane protein 3

Gene

PRM2

Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Biological processi

  • karyogamy involved in conjugation with cellular fusion Source: SGD
Complete GO annotation...

Enzyme and pathway databases

BioCyciYEAST:G3O-31309-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Pheromone-regulated membrane protein 3
Gene namesi
Name:PRM2
Ordered Locus Names:YIL037C
OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Taxonomic identifieri559292 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
ProteomesiUP000002311 Componenti: Chromosome IX

Organism-specific databases

CYGDiYIL037c.
EuPathDBiFungiDB:YIL037C.
SGDiS000001299. PRM2.

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei16 – 3621HelicalSequence AnalysisAdd
BLAST
Transmembranei320 – 34021HelicalSequence AnalysisAdd
BLAST
Transmembranei422 – 44221HelicalSequence AnalysisAdd
BLAST
Transmembranei634 – 65421HelicalSequence AnalysisAdd
BLAST

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 656656Pheromone-regulated membrane protein 3PRO_0000202994Add
BLAST

Proteomic databases

PaxDbiP40534.

Expressioni

Inductioni

By pheromone.1 Publication

Interactioni

Protein-protein interaction databases

BioGridi34953. 12 interactions.
DIPiDIP-6544N.
MINTiMINT-698729.

Structurei

3D structure databases

ProteinModelPortaliP40534.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiNOG299052.
InParanoidiP40534.
OrthoDBiEOG7QK0RF.

Sequencei

Sequence statusi: Complete.

P40534-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNNVHIIKPL SLPQRFFSCI FHPLLLIFFT SVILTIWGSF SVIDITMAKM
60 70 80 90 100
SHAQVKRNDT VSTFASISTA TATATTTATT TATMTAVTTQ HAIYSANSYS
110 120 130 140 150
LNKTFIDNTI DQYFESKLRS IESTVGTDMQ EKFKSYTDDI LDNKQKLIND
160 170 180 190 200
QISLETELIK EVLEVNNTIF NELLTKSQLI NDTWNEISED AMTIDKDSIS
210 220 230 240 250
QMASNLLLNY SMFDSIFGNY SRKLKSLQNF NGTITDFSTQ LDTSSTLSLN
260 270 280 290 300
FLRNSTDWLQ LKRNFTANLQ NEISILSGGS TEVTSSTSII KRSLKTNSEE
310 320 330 340 350
NSVLSAVKNH VFRKCKRMTI IFTVMYFAFV ILLMAIERIL FQLENQQVNL
360 370 380 390 400
VMSQINGLTG QTNFTKYNKV LKSLITTLNL STLYPIPYQL TKLINQKIFK
410 420 430 440 450
REPEKIDDKK VKKSKLFYCN WWIISNGAHL WLFGFLMLLI HWQIVTRLTN
460 470 480 490 500
FEVPSLPTFH KRAGPSLYKR EVWTDGNITT TIEGFINDSV SLLCENFQME
510 520 530 540 550
VNEKFITANL SLQTDPNLKV QSTDILNLWV NDTNTQFEKY LNESSQNWQG
560 570 580 590 600
IDLQVEPLLG SDSINEFLGQ YFLPTYEVTN TNSSFALDIQ KYGIINRGIN
610 620 630 640 650
ITNASVAALS SLSKRQIKDK EQKQTYFLHT VYKWGLLAVC LTILFHHMLI

FIILKL
Length:656
Mass (Da):75,021
Last modified:February 1, 1995 - v1
Checksum:i63787C6982065607
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Z46861 Genomic DNA. Translation: CAA86914.1.
BK006942 Genomic DNA. Translation: DAA08511.1.
PIRiS49941.
RefSeqiNP_012227.3. NM_001179387.3.

Genome annotation databases

EnsemblFungiiYIL037C; YIL037C; YIL037C.
GeneIDi854774.
KEGGisce:YIL037C.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Z46861 Genomic DNA. Translation: CAA86914.1.
BK006942 Genomic DNA. Translation: DAA08511.1.
PIRiS49941.
RefSeqiNP_012227.3. NM_001179387.3.

3D structure databases

ProteinModelPortaliP40534.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi34953. 12 interactions.
DIPiDIP-6544N.
MINTiMINT-698729.

Proteomic databases

PaxDbiP40534.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblFungiiYIL037C; YIL037C; YIL037C.
GeneIDi854774.
KEGGisce:YIL037C.

Organism-specific databases

CYGDiYIL037c.
EuPathDBiFungiDB:YIL037C.
SGDiS000001299. PRM2.

Phylogenomic databases

eggNOGiNOG299052.
InParanoidiP40534.
OrthoDBiEOG7QK0RF.

Enzyme and pathway databases

BioCyciYEAST:G3O-31309-MONOMER.

Miscellaneous databases

NextBioi977544.
PROiP40534.

Family and domain databases

ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 204508 / S288c.
  2. Cited for: GENOME REANNOTATION.
    Strain: ATCC 204508 / S288c.
  3. "Prm1p, a pheromone-regulated multispanning membrane protein, facilitates plasma membrane fusion during yeast mating."
    Heiman M.G., Walter P.
    J. Cell Biol. 151:719-730(2000) [PubMed] [Europe PMC] [Abstract]
    Cited for: NOMENCLATURE, INDUCTION.

Entry informationi

Entry nameiPRM2_YEAST
AccessioniPrimary (citable) accession number: P40534
Secondary accession number(s): D6VVP5
Entry historyi
Integrated into UniProtKB/Swiss-Prot: February 1, 1995
Last sequence update: February 1, 1995
Last modified: July 22, 2015
This is version 96 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Yeast
    Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD
  2. Yeast chromosome IX
    Yeast (Saccharomyces cerevisiae) chromosome IX: entries and gene names

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.