Skip Header

You are using a version of Internet Explorer that may not display all features of this website. Please upgrade to a modern browser.
Contribute Send feedback
Read comments (?) or add your own

P40534 (PRM2_YEAST) Reviewed, UniProtKB/Swiss-Prot

Last modified February 19, 2014. Version 89. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Pheromone-regulated membrane protein 3
Gene names
Name:PRM2
Ordered Locus Names:YIL037C
OrganismSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) [Reference proteome]
Taxonomic identifier559292 [NCBI]
Taxonomic lineageEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces

Protein attributes

Sequence length656 AA.
Sequence statusComplete.
Protein existenceEvidence at transcript level

General annotation (Comments)

Subcellular location

Membrane; Multi-pass membrane protein Potential.

Induction

By pheromone. Ref.3

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 656656Pheromone-regulated membrane protein 3
PRO_0000202994

Regions

Transmembrane16 – 3621Helical; Potential
Transmembrane320 – 34021Helical; Potential
Transmembrane422 – 44221Helical; Potential
Transmembrane634 – 65421Helical; Potential

Sequences

Sequence LengthMass (Da)Tools
P40534 [UniParc].

Last modified February 1, 1995. Version 1.
Checksum: 63787C6982065607

FASTA65675,021
        10         20         30         40         50         60 
MNNVHIIKPL SLPQRFFSCI FHPLLLIFFT SVILTIWGSF SVIDITMAKM SHAQVKRNDT 

        70         80         90        100        110        120 
VSTFASISTA TATATTTATT TATMTAVTTQ HAIYSANSYS LNKTFIDNTI DQYFESKLRS 

       130        140        150        160        170        180 
IESTVGTDMQ EKFKSYTDDI LDNKQKLIND QISLETELIK EVLEVNNTIF NELLTKSQLI 

       190        200        210        220        230        240 
NDTWNEISED AMTIDKDSIS QMASNLLLNY SMFDSIFGNY SRKLKSLQNF NGTITDFSTQ 

       250        260        270        280        290        300 
LDTSSTLSLN FLRNSTDWLQ LKRNFTANLQ NEISILSGGS TEVTSSTSII KRSLKTNSEE 

       310        320        330        340        350        360 
NSVLSAVKNH VFRKCKRMTI IFTVMYFAFV ILLMAIERIL FQLENQQVNL VMSQINGLTG 

       370        380        390        400        410        420 
QTNFTKYNKV LKSLITTLNL STLYPIPYQL TKLINQKIFK REPEKIDDKK VKKSKLFYCN 

       430        440        450        460        470        480 
WWIISNGAHL WLFGFLMLLI HWQIVTRLTN FEVPSLPTFH KRAGPSLYKR EVWTDGNITT 

       490        500        510        520        530        540 
TIEGFINDSV SLLCENFQME VNEKFITANL SLQTDPNLKV QSTDILNLWV NDTNTQFEKY 

       550        560        570        580        590        600 
LNESSQNWQG IDLQVEPLLG SDSINEFLGQ YFLPTYEVTN TNSSFALDIQ KYGIINRGIN 

       610        620        630        640        650 
ITNASVAALS SLSKRQIKDK EQKQTYFLHT VYKWGLLAVC LTILFHHMLI FIILKL 

« Hide

References

« Hide 'large scale' references
[1]"The nucleotide sequence of Saccharomyces cerevisiae chromosome IX."
Churcher C.M., Bowman S., Badcock K., Bankier A.T., Brown D., Chillingworth T., Connor R., Devlin K., Gentles S., Hamlin N., Harris D.E., Horsnell T., Hunt S., Jagels K., Jones M., Lye G., Moule S., Odell C. expand/collapse author list , Pearson D., Rajandream M.A., Rice P., Rowley N., Skelton J., Smith V., Walsh S.V., Whitehead S., Barrell B.G.
Nature 387:84-87(1997) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 204508 / S288c.
[2]Saccharomyces Genome Database
Submitted (DEC-2009) to the EMBL/GenBank/DDBJ databases
Cited for: GENOME REANNOTATION.
Strain: ATCC 204508 / S288c.
[3]"Prm1p, a pheromone-regulated multispanning membrane protein, facilitates plasma membrane fusion during yeast mating."
Heiman M.G., Walter P.
J. Cell Biol. 151:719-730(2000) [PubMed] [Europe PMC] [Abstract]
Cited for: NOMENCLATURE, INDUCTION.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
Z46861 Genomic DNA. Translation: CAA86914.1.
BK006942 Genomic DNA. Translation: DAA08511.1.
PIRS49941.
RefSeqNP_012227.3. NM_001179387.3.

3D structure databases

ProteinModelPortalP40534.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

BioGrid34953. 12 interactions.
DIPDIP-6544N.
MINTMINT-698729.
STRING4932.YIL037C.

Proteomic databases

PaxDbP40534.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblFungiYIL037C; YIL037C; YIL037C.
GeneID854774.
KEGGsce:YIL037C.

Organism-specific databases

CYGDYIL037c.
SGDS000001299. PRM2.

Phylogenomic databases

eggNOGNOG299052.
OMAHAIYSAN.
OrthoDBEOG7QK0RF.

Enzyme and pathway databases

BioCycYEAST:G3O-31309-MONOMER.

Gene expression databases

GenevestigatorP40534.

Family and domain databases

ProtoNetSearch...

Other

NextBio977544.

Entry information

Entry namePRM2_YEAST
AccessionPrimary (citable) accession number: P40534
Secondary accession number(s): D6VVP5
Entry history
Integrated into UniProtKB/Swiss-Prot: February 1, 1995
Last sequence update: February 1, 1995
Last modified: February 19, 2014
This is version 89 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Relevant documents

Yeast chromosome IX

Yeast (Saccharomyces cerevisiae) chromosome IX: entries and gene names

Yeast

Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD