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P40533

- TED1_YEAST

UniProt

P40533 - TED1_YEAST

Protein

Protein TED1

Gene

TED1

Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed - Annotation score: 3 out of 5- Experimental evidence at protein leveli
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    • History
      Entry version 96 (01 Oct 2014)
      Sequence version 1 (01 Feb 1995)
      Previous versions | rss
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    Functioni

    Acts together with EMP24 and ERV25 in cargo exit from the endoplasmic reticulum.1 Publication

    GO - Molecular functioni

    1. hydrolase activity Source: InterPro

    GO - Biological processi

    1. ER to Golgi vesicle-mediated transport Source: SGD

    Enzyme and pathway databases

    BioCyciYEAST:G3O-31311-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Protein TED1
    Alternative name(s):
    Trafficking of EMP24/ERV25-dependent cargo disrupted protein 1
    Gene namesi
    Name:TED1
    Ordered Locus Names:YIL039W
    OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
    Taxonomic identifieri559292 [NCBI]
    Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
    ProteomesiUP000002311: Chromosome IX

    Organism-specific databases

    CYGDiYIL039w.
    SGDiS000001301. TED1.

    Subcellular locationi

    GO - Cellular componenti

    1. endoplasmic reticulum membrane Source: UniProtKB-SubCell
    2. integral component of membrane Source: UniProtKB-KW

    Keywords - Cellular componenti

    Endoplasmic reticulum, Membrane

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 473473Protein TED1PRO_0000202993Add
    BLAST

    Amino acid modifications

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Glycosylationi38 – 381N-linked (GlcNAc...)Sequence Analysis
    Glycosylationi147 – 1471N-linked (GlcNAc...)Sequence Analysis
    Glycosylationi229 – 2291N-linked (GlcNAc...)Sequence Analysis
    Glycosylationi266 – 2661N-linked (GlcNAc...)Sequence Analysis
    Glycosylationi307 – 3071N-linked (GlcNAc...)Sequence Analysis

    Post-translational modificationi

    N-glycosylated.1 Publication

    Keywords - PTMi

    Glycoprotein

    Proteomic databases

    MaxQBiP40533.
    PaxDbiP40533.
    PeptideAtlasiP40533.

    Expressioni

    Gene expression databases

    GenevestigatoriP40533.

    Interactioni

    Protein-protein interaction databases

    BioGridi34951. 77 interactions.
    DIPiDIP-4575N.
    IntActiP40533. 2 interactions.
    MINTiMINT-503750.
    STRINGi4932.YIL039W.

    Structurei

    3D structure databases

    ProteinModelPortaliP40533.
    ModBaseiSearch...
    MobiDBiSearch...

    Topological domain

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Topological domaini1 – 88CytoplasmicSequence Analysis
    Topological domaini30 – 451422LumenalSequence AnalysisAdd
    BLAST
    Topological domaini473 – 4731CytoplasmicSequence Analysis

    Transmembrane

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Transmembranei9 – 2921HelicalSequence AnalysisAdd
    BLAST
    Transmembranei452 – 47221HelicalSequence AnalysisAdd
    BLAST

    Family & Domainsi

    Keywords - Domaini

    Transmembrane, Transmembrane helix

    Phylogenomic databases

    eggNOGiNOG302374.
    HOGENOMiHOG000093805.
    OMAiGDPQING.
    OrthoDBiEOG74TX7M.

    Family and domain databases

    Gene3Di3.60.21.10. 2 hits.
    InterProiIPR004843. Calcineurin-like_PHP_apaH.
    IPR029052. Metallo-depent_PP-like.
    [Graphical view]
    PfamiPF00149. Metallophos. 1 hit.
    [Graphical view]
    SUPFAMiSSF56300. SSF56300. 3 hits.

    Sequencei

    Sequence statusi: Complete.

    P40533-1 [UniParc]FASTAAdd to Basket

    « Hide

    MLRCAVKKFA YFATFLTIVA NIYIYTYPSF HPEQCSWNCS NKNAPLQKDL    50
    TFVDKVKNYF SDVREQWHGS HASAGNDEDI HILAFGDPQI KGIWPKTPYV 100
    SRLDTYGNDY YLGHIYDMMQ QRLKPQVVTV MGDLFSSQWI GDSEFHNRTK 150
    RYISRIFKRD PTSIENIKQQ NLDEKGQYKA NWPEWGDRFN EILDNVKENE 200
    ADNQELSFGF GYENIHSWNP DLEDFLIINI TGNHDVGYSG DATYQHMTRF 250
    HDLFGKDNYW IEYETNTTHP WRIVVLNDLL LEGPALQPEF VEATWIFLNQ 300
    LNERKFNGST VLLTHVPFYK REGLCVDGPD TRYYPDAHAP ESYKSGLLRS 350
    QNHLSESVSN QVLNMIFENG KPGIILTGHD HEGCETVYNK KSTSTWEATK 400
    NIESDVFVKE ITVKSMMGEF NGNTGLVTGH FNTDSMTWEW TFSLCPFAIQ 450
    HVWWFAKVSL LVTIFTWSSL LFV 473
    Length:473
    Mass (Da):54,928
    Last modified:February 1, 1995 - v1
    Checksum:i3D8AF321C9BAFDE8
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    Z46861 Genomic DNA. Translation: CAA86912.1.
    BK006942 Genomic DNA. Translation: DAA08509.1.
    PIRiS49939.
    RefSeqiNP_012225.1. NM_001179389.1.

    Genome annotation databases

    EnsemblFungiiYIL039W; YIL039W; YIL039W.
    GeneIDi854772.
    KEGGisce:YIL039W.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    Z46861 Genomic DNA. Translation: CAA86912.1 .
    BK006942 Genomic DNA. Translation: DAA08509.1 .
    PIRi S49939.
    RefSeqi NP_012225.1. NM_001179389.1.

    3D structure databases

    ProteinModelPortali P40533.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    BioGridi 34951. 77 interactions.
    DIPi DIP-4575N.
    IntActi P40533. 2 interactions.
    MINTi MINT-503750.
    STRINGi 4932.YIL039W.

    Proteomic databases

    MaxQBi P40533.
    PaxDbi P40533.
    PeptideAtlasi P40533.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblFungii YIL039W ; YIL039W ; YIL039W .
    GeneIDi 854772.
    KEGGi sce:YIL039W.

    Organism-specific databases

    CYGDi YIL039w.
    SGDi S000001301. TED1.

    Phylogenomic databases

    eggNOGi NOG302374.
    HOGENOMi HOG000093805.
    OMAi GDPQING.
    OrthoDBi EOG74TX7M.

    Enzyme and pathway databases

    BioCyci YEAST:G3O-31311-MONOMER.

    Miscellaneous databases

    NextBioi 977538.

    Gene expression databases

    Genevestigatori P40533.

    Family and domain databases

    Gene3Di 3.60.21.10. 2 hits.
    InterProi IPR004843. Calcineurin-like_PHP_apaH.
    IPR029052. Metallo-depent_PP-like.
    [Graphical view ]
    Pfami PF00149. Metallophos. 1 hit.
    [Graphical view ]
    SUPFAMi SSF56300. SSF56300. 3 hits.
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC 204508 / S288c.
    2. Cited for: GENOME REANNOTATION.
      Strain: ATCC 204508 / S288c.
    3. Cited for: SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS].
    4. Cited for: LEVEL OF PROTEIN EXPRESSION [LARGE SCALE ANALYSIS].
    5. "Identification of yeast proteins necessary for cell-surface function of a potassium channel."
      Haass F.A., Jonikas M., Walter P., Weissman J.S., Jan Y.-N., Jan L.Y., Schuldiner M.
      Proc. Natl. Acad. Sci. U.S.A. 104:18079-18084(2007) [PubMed] [Europe PMC] [Abstract]
      Cited for: FUNCTION, SUBCELLULAR LOCATION.
    6. "Global analysis of the glycoproteome in Saccharomyces cerevisiae reveals new roles for protein glycosylation in eukaryotes."
      Kung L.A., Tao S.-C., Qian J., Smith M.G., Snyder M., Zhu H.
      Mol. Syst. Biol. 5:308-308(2009) [PubMed] [Europe PMC] [Abstract]
      Cited for: GLYCOSYLATION [LARGE SCALE ANALYSIS].

    Entry informationi

    Entry nameiTED1_YEAST
    AccessioniPrimary (citable) accession number: P40533
    Secondary accession number(s): D6VVP3
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: February 1, 1995
    Last sequence update: February 1, 1995
    Last modified: October 1, 2014
    This is version 96 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programFungal Protein Annotation Program

    Miscellaneousi

    Miscellaneous

    Present with 1070 molecules/cell in log phase SD medium.1 Publication

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. Yeast
      Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD
    2. Yeast chromosome IX
      Yeast (Saccharomyces cerevisiae) chromosome IX: entries and gene names

    External Data

    Dasty 3