Skip Header

You are using a version of Internet Explorer that may not display all features of this website. Please upgrade to a modern browser.
Contribute Send feedback
Read comments (?) or add your own

P40533 (TED1_YEAST) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 92. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Protein TED1
Alternative name(s):
Trafficking of EMP24/ERV25-dependent cargo disrupted protein 1
Gene names
Name:TED1
Ordered Locus Names:YIL039W
OrganismSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) [Reference proteome]
Taxonomic identifier559292 [NCBI]
Taxonomic lineageEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces

Protein attributes

Sequence length473 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

General annotation (Comments)

Function

Acts together with EMP24 and ERV25 in cargo exit from the endoplasmic reticulum. Ref.5

Subcellular location

Endoplasmic reticulum membrane; Multi-pass membrane protein Potential Ref.3 Ref.5.

Post-translational modification

N-glycosylated.

Miscellaneous

Present with 1070 molecules/cell in log phase SD medium.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 473473Protein TED1
PRO_0000202993

Regions

Topological domain1 – 88Cytoplasmic Potential
Transmembrane9 – 2921Helical; Potential
Topological domain30 – 451422Lumenal Potential
Transmembrane452 – 47221Helical; Potential
Topological domain4731Cytoplasmic Potential

Amino acid modifications

Glycosylation381N-linked (GlcNAc...) Potential
Glycosylation1471N-linked (GlcNAc...) Potential
Glycosylation2291N-linked (GlcNAc...) Potential
Glycosylation2661N-linked (GlcNAc...) Potential
Glycosylation3071N-linked (GlcNAc...) Potential

Sequences

Sequence LengthMass (Da)Tools
P40533 [UniParc].

Last modified February 1, 1995. Version 1.
Checksum: 3D8AF321C9BAFDE8

FASTA47354,928
        10         20         30         40         50         60 
MLRCAVKKFA YFATFLTIVA NIYIYTYPSF HPEQCSWNCS NKNAPLQKDL TFVDKVKNYF 

        70         80         90        100        110        120 
SDVREQWHGS HASAGNDEDI HILAFGDPQI KGIWPKTPYV SRLDTYGNDY YLGHIYDMMQ 

       130        140        150        160        170        180 
QRLKPQVVTV MGDLFSSQWI GDSEFHNRTK RYISRIFKRD PTSIENIKQQ NLDEKGQYKA 

       190        200        210        220        230        240 
NWPEWGDRFN EILDNVKENE ADNQELSFGF GYENIHSWNP DLEDFLIINI TGNHDVGYSG 

       250        260        270        280        290        300 
DATYQHMTRF HDLFGKDNYW IEYETNTTHP WRIVVLNDLL LEGPALQPEF VEATWIFLNQ 

       310        320        330        340        350        360 
LNERKFNGST VLLTHVPFYK REGLCVDGPD TRYYPDAHAP ESYKSGLLRS QNHLSESVSN 

       370        380        390        400        410        420 
QVLNMIFENG KPGIILTGHD HEGCETVYNK KSTSTWEATK NIESDVFVKE ITVKSMMGEF 

       430        440        450        460        470 
NGNTGLVTGH FNTDSMTWEW TFSLCPFAIQ HVWWFAKVSL LVTIFTWSSL LFV 

« Hide

References

« Hide 'large scale' references
[1]"The nucleotide sequence of Saccharomyces cerevisiae chromosome IX."
Churcher C.M., Bowman S., Badcock K., Bankier A.T., Brown D., Chillingworth T., Connor R., Devlin K., Gentles S., Hamlin N., Harris D.E., Horsnell T., Hunt S., Jagels K., Jones M., Lye G., Moule S., Odell C. expand/collapse author list , Pearson D., Rajandream M.A., Rice P., Rowley N., Skelton J., Smith V., Walsh S.V., Whitehead S., Barrell B.G.
Nature 387:84-87(1997) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 204508 / S288c.
[2]Saccharomyces Genome Database
Submitted (DEC-2009) to the EMBL/GenBank/DDBJ databases
Cited for: GENOME REANNOTATION.
Strain: ATCC 204508 / S288c.
[3]"Global analysis of protein localization in budding yeast."
Huh W.-K., Falvo J.V., Gerke L.C., Carroll A.S., Howson R.W., Weissman J.S., O'Shea E.K.
Nature 425:686-691(2003) [PubMed] [Europe PMC] [Abstract]
Cited for: SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS].
[4]"Global analysis of protein expression in yeast."
Ghaemmaghami S., Huh W.-K., Bower K., Howson R.W., Belle A., Dephoure N., O'Shea E.K., Weissman J.S.
Nature 425:737-741(2003) [PubMed] [Europe PMC] [Abstract]
Cited for: LEVEL OF PROTEIN EXPRESSION [LARGE SCALE ANALYSIS].
[5]"Identification of yeast proteins necessary for cell-surface function of a potassium channel."
Haass F.A., Jonikas M., Walter P., Weissman J.S., Jan Y.-N., Jan L.Y., Schuldiner M.
Proc. Natl. Acad. Sci. U.S.A. 104:18079-18084(2007) [PubMed] [Europe PMC] [Abstract]
Cited for: FUNCTION, SUBCELLULAR LOCATION.
[6]"Global analysis of the glycoproteome in Saccharomyces cerevisiae reveals new roles for protein glycosylation in eukaryotes."
Kung L.A., Tao S.-C., Qian J., Smith M.G., Snyder M., Zhu H.
Mol. Syst. Biol. 5:308-308(2009) [PubMed] [Europe PMC] [Abstract]
Cited for: GLYCOSYLATION [LARGE SCALE ANALYSIS].
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
Z46861 Genomic DNA. Translation: CAA86912.1.
BK006942 Genomic DNA. Translation: DAA08509.1.
PIRS49939.
RefSeqNP_012225.1. NM_001179389.1.

3D structure databases

ProteinModelPortalP40533.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

BioGrid34951. 76 interactions.
DIPDIP-4575N.
IntActP40533. 2 interactions.
MINTMINT-503750.
STRING4932.YIL039W.

Proteomic databases

PaxDbP40533.
PeptideAtlasP40533.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblFungiYIL039W; YIL039W; YIL039W.
GeneID854772.
KEGGsce:YIL039W.

Organism-specific databases

CYGDYIL039w.
SGDS000001301. TED1.

Phylogenomic databases

eggNOGNOG302374.
HOGENOMHOG000093805.
OMAGDPQING.
OrthoDBEOG74TX7M.

Enzyme and pathway databases

BioCycYEAST:G3O-31311-MONOMER.

Gene expression databases

GenevestigatorP40533.

Family and domain databases

InterProIPR004843. Calcineurin-like_PHP_apaH.
[Graphical view]
PfamPF00149. Metallophos. 1 hit.
[Graphical view]
ProtoNetSearch...

Other

NextBio977538.

Entry information

Entry nameTED1_YEAST
AccessionPrimary (citable) accession number: P40533
Secondary accession number(s): D6VVP3
Entry history
Integrated into UniProtKB/Swiss-Prot: February 1, 1995
Last sequence update: February 1, 1995
Last modified: April 16, 2014
This is version 92 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Relevant documents

Yeast chromosome IX

Yeast (Saccharomyces cerevisiae) chromosome IX: entries and gene names

Yeast

Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD