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Reviewed, UniProtKB/Swiss-Prot P40504 (KTR7_YEAST)

Last modified February 9, 2010. Version 78. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (3) | Third-party data | Customize display text xml rdf/xml gff fasta
Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Binary interactions · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents

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Names and origin

Protein namesRecommended name:
    Probable mannosyltransferase KTR7
    EC=2.4.1.131
Gene names
Name: KTR7
Ordered Locus Names: YIL085C
OrganismSaccharomyces cerevisiae (Baker's yeast) [Complete proteome]
Taxonomic identifier4932 [NCBI]
Taxonomic lineageEukaryota › Fungi › Dikarya › Ascomycota › Saccharomycotina › Saccharomycetes › Saccharomycetales › Saccharomycetaceae › Saccharomyces

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Protein attributes

Sequence length517 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level.

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General annotation (Comments)

Function

Possible glycosyltransferase.

Catalytic activity

Transfers an alpha-D-mannosyl residue from GDP-mannose into lipid-linked oligosaccharide, forming an alpha-(1->2)-D-mannosyl-D-mannose linkage.

Subcellular location

Membrane; Single-pass type II membrane protein Probable.

Miscellaneous

Present with 2890 molecules/cell in log phase SD medium. Ref.3

Sequence similarities

Belongs to the glycosyltransferase 15 family.

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Binary interactions

With

Entry

#Exp.

IntAct

Notes

ECM16Q042171EBI-10011,EBI-1820

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Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 517517Probable mannosyltransferase KTR7
PRO_0000208248

Regions

Topological domain1 – 2323Cytoplasmic Potential
Transmembrane24 – 4421Signal-anchor for type II membrane protein
Topological domain45 – 517473Lumenal Potential
Region45 – 8541Stem region By similarity
Region86 – 517432Catalytic By similarity

Sites

Active site3671Nucleophile Potential

Amino acid modifications

Glycosylation891N-linked (GlcNAc...) Potential
Glycosylation1441N-linked (GlcNAc...) Potential

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Sequences

Sequence LengthMass (Da)Tools
P40504-1 [UniParc].

Last modified February 1, 1995. Version 1.
Checksum: 3E02FA8AA5456DEF

FASTA51761,438
        10         20         30         40         50         60 
MAIRLNPKVR RFLLDKCRQK RYGFLFLGCI FAILYCMGTW PFFAKDIVHD PNNLPYSLQD 

        70         80         90        100        110        120 
YSTDKDEPFF RGCTDTKLYL QNPAYSKMNA SFVMLTRNEE IEDVLKTMRS IEGHFNKWFK 

       130        140        150        160        170        180 
YPYVFLNDDP FTDHFKDQIQ AATNATVEFG TVDEIMWEFP AKVRNSLQFK ASLEDQNDRG 

       190        200        210        220        230        240 
IMYGNMESYH KMCRFYSGIF YKHPLVSKYE WYWRIEPDVD FFCDISYDPF FEMAKHNKKY 

       250        260        270        280        290        300 
GFTVLITELY WTVPNLFRTT KSFIKKTAGL KENLGTLWKL FTFNYNILDT DDEEISRWVN 

       310        320        330        340        350        360 
FPWDAKPKLT EKLMVDFLLE NHGQVNNEED LEGIQYLVER ARSKVPMLED SLEGEDYNLC 

       370        380        390        400        410        420 
HFWSNFEIAR VDLFDNEIYN AYFKFLEESG GFWTERWGDA PIHSIGLGMT LDLEDVHYFR 

       430        440        450        460        470        480 
DIGYRHSSLQ HCPKNALQSQ ENLNTFDEGY NFGCGCRCVC PKKGEDIEDH STPCMDIFFE 

       490        500        510 
LLHGREYEKE FPGCYKPSIK DKDVIEEIRR ENFRVIE

« Hide

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References

« Hide 'large scale' references
[1]"The nucleotide sequence of Saccharomyces cerevisiae chromosome IX."
Churcher C.M., Bowman S., Badcock K., Bankier A.T., Brown D., Chillingworth T., Connor R., Devlin K., Gentles S., Hamlin N., Harris D.E., Horsnell T., Hunt S., Jagels K., Jones M., Lye G., Moule S., Odell C. expand/collapse author list , Pearson D., Rajandream M.A., Rice P., Rowley N., Skelton J., Smith V., Walsh S.V., Whitehead S., Barrell B.G.
Nature 387:84-87(1997) [PubMed: 9169870] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 204511 / S288c / AB972.
[2]"Completion of the Saccharomyces cerevisiae genome sequence allows identification of KTR5, KTR6 and KTR7 and definition of the nine-membered KRE2/MNT1 mannosyltransferase gene family in this organism."
Lussier M., Sdicu A.-M., Winnett E., Vo D.H., Sheraton J., Duesterhoeft A., Storms R.K., Bussey H.
Yeast 13:267-274(1997) [PubMed: 9090056] [Abstract]
Cited for: CHARACTERIZATION.
[3]"Global analysis of protein expression in yeast."
Ghaemmaghami S., Huh W.-K., Bower K., Howson R.W., Belle A., Dephoure N., O'Shea E.K., Weissman J.S.
Nature 425:737-741(2003) [PubMed: 14562106] [Abstract]
Cited for: LEVEL OF PROTEIN EXPRESSION [LARGE SCALE ANALYSIS].
+Additional computationally mapped references.

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Cross-references

Sequence databases

EMBL
GenBank
DDBJ		Z46728 Genomic DNA. Translation: CAA86709.1.
PIRS49795.
RefSeqNP_012181.1.

3D structure databases

SMRP40504. Positions 86-482.
ModBaseSearch...

Protein-protein interaction databases

DIPDIP-4677N.
IntActP40504. 5 interactions.
STRINGP40504.

Protein family/group databases

CAZyGT15. Glycosyltransferase Family 15.

Genome annotation databases

EnsemblYIL085C; YIL085C; YIL085C; Saccharomyces cerevisiae. [Genome view]
GeneID854724.
KEGGsce:YIL085C.
NMPDRfig|4932.3.peg.1708.

Organism-specific databases

CYGDYIL085c.
SGDS000001347. KTR7.

Phylogenomic databases

eggNOGfuNOG05672.
HOGENOMHBG396033.
OMACINEWAS.
OrthoDBEOG9V18H9.
PhylomeDBP40504.

Enzyme and pathway databases

BRENDA2.4.1.131. 250.

Gene expression databases

ArrayExpressP40504.
GenevestigatorP40504.
GermOnlineYIL085C. Saccharomyces cerevisiae.

Family and domain databases

InterProIPR002685. Glyco_trans_15.
[Graphical view]
PfamPF01793. Glyco_transf_15. 1 hit.
[Graphical view]
PIRSFPIRSF018153. Glyco_trans_15. 1 hit.
ProtoNetSearch...

Other Resources

NextBio977409.

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Entry information

Entry nameKTR7_YEAST
AccessionPrimary (citable) accession number: P40504
Entry history
Integrated into UniProtKB/Swiss-Prot: February 1, 1995
Last sequence update: February 1, 1995
Last modified: February 9, 2010
This is version 78 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation projectFPAP (Fungal Proteome Annotation Project)

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Relevant documents

SIMILARITY comments

Index of protein domains and families

Yeast

Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD

Yeast chromosome IX

Yeast (Saccharomyces cerevisiae) chromosome IX: entries and gene names

Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Binary interactions · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents