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P40502

- AIM19_YEAST

UniProt

P40502 - AIM19_YEAST

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Protein

Altered inheritance of mitochondria protein 19, mitochondrial

Gene
AIM19, YIL087C
Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed - Annotation score: 3 out of 5 - Experimental evidence at protein leveli

Functioni

Enzyme and pathway databases

BioCyciYEAST:G3O-31347-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Altered inheritance of mitochondria protein 19, mitochondrial
Gene namesi
Name:AIM19
Ordered Locus Names:YIL087C
OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Taxonomic identifieri559292 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
ProteomesiUP000002311: Chromosome IX

Organism-specific databases

CYGDiYIL087c.
SGDiS000001349. AIM19.

Subcellular locationi

Mitochondrion membrane; Multi-pass membrane protein 3 Publications

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei31 – 4818Helical; Reviewed predictionAdd
BLAST
Transmembranei80 – 9617Helical; Reviewed predictionAdd
BLAST
Transmembranei103 – 11917Helical; Reviewed predictionAdd
BLAST
Transmembranei131 – 14717Helical; Reviewed predictionAdd
BLAST

GO - Cellular componenti

  1. integral component of membrane Source: UniProtKB-KW
  2. mitochondrial membrane Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Membrane, Mitochondrion

Pathology & Biotechi

Disruption phenotypei

Increases frequency of mitochondrial genome loss.1 Publication

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Initiator methioninei1 – 11Removed1 Publication
Chaini2 – 157156Altered inheritance of mitochondria protein 19, mitochondrialPRO_0000202977Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei2 – 21N-acetylserine1 Publication

Keywords - PTMi

Acetylation

Proteomic databases

MaxQBiP40502.
PaxDbiP40502.

Expressioni

Gene expression databases

GenevestigatoriP40502.

Interactioni

Protein-protein interaction databases

BioGridi34906. 18 interactions.
MINTiMINT-4489864.
STRINGi4932.YIL087C.

Structurei

3D structure databases

ProteinModelPortaliP40502.

Family & Domainsi

Sequence similaritiesi

Belongs to the AIM19 family.

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiNOG84345.
OMAiSANSWTI.
OrthoDBiEOG7PZS9R.

Family and domain databases

InterProiIPR019419. AIM19.
[Graphical view]
PfamiPF10315. DUF2416. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

P40502-1 [UniParc]FASTAAdd to Basket

« Hide

MSAKPATDDA KDELLSPFRR LYALTRTPYP ALANAALLAS TPVLSPSFKV    50
PPTQSPALSI PMSRVFSKSS TARIGITTKT ALFFSTMQAI GAYMIYDNDL 100
ENGAGFIATW SALYLIVGGK KSFSALRYGR TWPLVLSSVS LANAVLYGQR 150
FLATGFQ 157
Length:157
Mass (Da):16,924
Last modified:February 1, 1995 - v1
Checksum:i32C547FA27327AFB
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
Z46728 Genomic DNA. Translation: CAA86707.1.
AY558539 Genomic DNA. Translation: AAS56865.1.
BK006942 Genomic DNA. Translation: DAA08466.1.
PIRiS49793.
RefSeqiNP_012179.3. NM_001179435.3.

Genome annotation databases

EnsemblFungiiYIL087C; YIL087C; YIL087C.
GeneIDi854722.
KEGGisce:YIL087C.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
Z46728 Genomic DNA. Translation: CAA86707.1 .
AY558539 Genomic DNA. Translation: AAS56865.1 .
BK006942 Genomic DNA. Translation: DAA08466.1 .
PIRi S49793.
RefSeqi NP_012179.3. NM_001179435.3.

3D structure databases

ProteinModelPortali P40502.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

BioGridi 34906. 18 interactions.
MINTi MINT-4489864.
STRINGi 4932.YIL087C.

Proteomic databases

MaxQBi P40502.
PaxDbi P40502.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblFungii YIL087C ; YIL087C ; YIL087C .
GeneIDi 854722.
KEGGi sce:YIL087C.

Organism-specific databases

CYGDi YIL087c.
SGDi S000001349. AIM19.

Phylogenomic databases

eggNOGi NOG84345.
OMAi SANSWTI.
OrthoDBi EOG7PZS9R.

Enzyme and pathway databases

BioCyci YEAST:G3O-31347-MONOMER.

Miscellaneous databases

NextBioi 977406.

Gene expression databases

Genevestigatori P40502.

Family and domain databases

InterProi IPR019419. AIM19.
[Graphical view ]
Pfami PF10315. DUF2416. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 204508 / S288c.
  2. Cited for: GENOME REANNOTATION.
    Strain: ATCC 204508 / S288c.
  3. Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
    Strain: ATCC 204508 / S288c.
  4. Cited for: SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS].
  5. "Toward the complete yeast mitochondrial proteome: multidimensional separation techniques for mitochondrial proteomics."
    Reinders J., Zahedi R.P., Pfanner N., Meisinger C., Sickmann A.
    J. Proteome Res. 5:1543-1554(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS].
  6. "Computationally driven, quantitative experiments discover genes required for mitochondrial biogenesis."
    Hess D.C., Myers C.L., Huttenhower C., Hibbs M.A., Hayes A.P., Paw J., Clore J.J., Mendoza R.M., Luis B.S., Nislow C., Giaever G., Costanzo M., Troyanskaya O.G., Caudy A.A.
    PLoS Genet. 5:E1000407-E1000407(2009) [PubMed] [Europe PMC] [Abstract]
    Cited for: DISRUPTION PHENOTYPE.
  7. Cited for: SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS].
    Strain: ATCC 76625 / YPH499.
  8. Cited for: ACETYLATION [LARGE SCALE ANALYSIS] AT SER-2, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS], CLEAVAGE OF INITIATOR METHIONINE [LARGE SCALE ANALYSIS].

Entry informationi

Entry nameiAIM19_YEAST
AccessioniPrimary (citable) accession number: P40502
Secondary accession number(s): D6VVK0
Entry historyi
Integrated into UniProtKB/Swiss-Prot: February 1, 1995
Last sequence update: February 1, 1995
Last modified: May 14, 2014
This is version 89 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Yeast
    Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD
  3. Yeast chromosome IX
    Yeast (Saccharomyces cerevisiae) chromosome IX: entries and gene names

External Data

Dasty 3

Similar proteinsi