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P40502

- AIM19_YEAST

UniProt

P40502 - AIM19_YEAST

Protein

Altered inheritance of mitochondria protein 19, mitochondrial

Gene

AIM19

Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed - Annotation score: 3 out of 5- Experimental evidence at protein leveli
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    • History
      Entry version 90 (01 Oct 2014)
      Sequence version 1 (01 Feb 1995)
      Previous versions | rss
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    Functioni

    Enzyme and pathway databases

    BioCyciYEAST:G3O-31347-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Altered inheritance of mitochondria protein 19, mitochondrial
    Gene namesi
    Name:AIM19
    Ordered Locus Names:YIL087C
    OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
    Taxonomic identifieri559292 [NCBI]
    Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
    ProteomesiUP000002311: Chromosome IX

    Organism-specific databases

    CYGDiYIL087c.
    SGDiS000001349. AIM19.

    Subcellular locationi

    Mitochondrion membrane 3 Publications; Multi-pass membrane protein 3 Publications

    GO - Cellular componenti

    1. integral component of membrane Source: UniProtKB-KW
    2. mitochondrial membrane Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Membrane, Mitochondrion

    Pathology & Biotechi

    Disruption phenotypei

    Increases frequency of mitochondrial genome loss.1 Publication

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Initiator methioninei1 – 11Removed1 Publication
    Chaini2 – 157156Altered inheritance of mitochondria protein 19, mitochondrialPRO_0000202977Add
    BLAST

    Amino acid modifications

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Modified residuei2 – 21N-acetylserine1 Publication

    Keywords - PTMi

    Acetylation

    Proteomic databases

    MaxQBiP40502.
    PaxDbiP40502.

    Expressioni

    Gene expression databases

    GenevestigatoriP40502.

    Interactioni

    Protein-protein interaction databases

    BioGridi34906. 18 interactions.
    MINTiMINT-4489864.
    STRINGi4932.YIL087C.

    Structurei

    3D structure databases

    ProteinModelPortaliP40502.
    ModBaseiSearch...
    MobiDBiSearch...

    Transmembrane

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Transmembranei31 – 4818HelicalSequence AnalysisAdd
    BLAST
    Transmembranei80 – 9617HelicalSequence AnalysisAdd
    BLAST
    Transmembranei103 – 11917HelicalSequence AnalysisAdd
    BLAST
    Transmembranei131 – 14717HelicalSequence AnalysisAdd
    BLAST

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the AIM19 family.Curated

    Keywords - Domaini

    Transmembrane, Transmembrane helix

    Phylogenomic databases

    eggNOGiNOG84345.
    OMAiSANSWTI.
    OrthoDBiEOG7PZS9R.

    Family and domain databases

    InterProiIPR019419. AIM19.
    [Graphical view]
    PfamiPF10315. DUF2416. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Sequence processingi: The displayed sequence is further processed into a mature form.

    P40502-1 [UniParc]FASTAAdd to Basket

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    MSAKPATDDA KDELLSPFRR LYALTRTPYP ALANAALLAS TPVLSPSFKV    50
    PPTQSPALSI PMSRVFSKSS TARIGITTKT ALFFSTMQAI GAYMIYDNDL 100
    ENGAGFIATW SALYLIVGGK KSFSALRYGR TWPLVLSSVS LANAVLYGQR 150
    FLATGFQ 157
    Length:157
    Mass (Da):16,924
    Last modified:February 1, 1995 - v1
    Checksum:i32C547FA27327AFB
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    Z46728 Genomic DNA. Translation: CAA86707.1.
    AY558539 Genomic DNA. Translation: AAS56865.1.
    BK006942 Genomic DNA. Translation: DAA08466.1.
    PIRiS49793.
    RefSeqiNP_012179.3. NM_001179435.3.

    Genome annotation databases

    EnsemblFungiiYIL087C; YIL087C; YIL087C.
    GeneIDi854722.
    KEGGisce:YIL087C.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    Z46728 Genomic DNA. Translation: CAA86707.1 .
    AY558539 Genomic DNA. Translation: AAS56865.1 .
    BK006942 Genomic DNA. Translation: DAA08466.1 .
    PIRi S49793.
    RefSeqi NP_012179.3. NM_001179435.3.

    3D structure databases

    ProteinModelPortali P40502.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    BioGridi 34906. 18 interactions.
    MINTi MINT-4489864.
    STRINGi 4932.YIL087C.

    Proteomic databases

    MaxQBi P40502.
    PaxDbi P40502.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblFungii YIL087C ; YIL087C ; YIL087C .
    GeneIDi 854722.
    KEGGi sce:YIL087C.

    Organism-specific databases

    CYGDi YIL087c.
    SGDi S000001349. AIM19.

    Phylogenomic databases

    eggNOGi NOG84345.
    OMAi SANSWTI.
    OrthoDBi EOG7PZS9R.

    Enzyme and pathway databases

    BioCyci YEAST:G3O-31347-MONOMER.

    Miscellaneous databases

    NextBioi 977406.

    Gene expression databases

    Genevestigatori P40502.

    Family and domain databases

    InterProi IPR019419. AIM19.
    [Graphical view ]
    Pfami PF10315. DUF2416. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC 204508 / S288c.
    2. Cited for: GENOME REANNOTATION.
      Strain: ATCC 204508 / S288c.
    3. Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
      Strain: ATCC 204508 / S288c.
    4. Cited for: SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS].
    5. "Toward the complete yeast mitochondrial proteome: multidimensional separation techniques for mitochondrial proteomics."
      Reinders J., Zahedi R.P., Pfanner N., Meisinger C., Sickmann A.
      J. Proteome Res. 5:1543-1554(2006) [PubMed] [Europe PMC] [Abstract]
      Cited for: SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS].
    6. "Computationally driven, quantitative experiments discover genes required for mitochondrial biogenesis."
      Hess D.C., Myers C.L., Huttenhower C., Hibbs M.A., Hayes A.P., Paw J., Clore J.J., Mendoza R.M., Luis B.S., Nislow C., Giaever G., Costanzo M., Troyanskaya O.G., Caudy A.A.
      PLoS Genet. 5:E1000407-E1000407(2009) [PubMed] [Europe PMC] [Abstract]
      Cited for: DISRUPTION PHENOTYPE.
    7. Cited for: SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS].
      Strain: ATCC 76625 / YPH499.
    8. Cited for: ACETYLATION [LARGE SCALE ANALYSIS] AT SER-2, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS], CLEAVAGE OF INITIATOR METHIONINE [LARGE SCALE ANALYSIS].

    Entry informationi

    Entry nameiAIM19_YEAST
    AccessioniPrimary (citable) accession number: P40502
    Secondary accession number(s): D6VVK0
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: February 1, 1995
    Last sequence update: February 1, 1995
    Last modified: October 1, 2014
    This is version 90 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programFungal Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. SIMILARITY comments
      Index of protein domains and families
    2. Yeast
      Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD
    3. Yeast chromosome IX
      Yeast (Saccharomyces cerevisiae) chromosome IX: entries and gene names

    External Data

    Dasty 3