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Protein

Protein FYV10

Gene

FYV10

Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Involved in the proteasome-dependent degradation of fructose-1,6-bisphosphatase and required for survival upon exposure to K1 killer toxin.2 Publications

Miscellaneous

Present with 784 molecules/cell in log phase SD medium.1 Publication

GO - Biological processi

  • negative regulation of apoptotic process Source: SGD
  • negative regulation of gluconeogenesis Source: SGD
  • proteasome-mediated ubiquitin-dependent protein catabolic process Source: SGD
  • protein ubiquitination Source: GOC

Enzyme and pathway databases

BioCyciYEAST:G3O-31356-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Protein FYV10
Alternative name(s):
Function required for yeast viability protein 10
Glucose-induced degradation protein 9
Gene namesi
Name:FYV10
Synonyms:GID9
Ordered Locus Names:YIL097W
OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Taxonomic identifieri559292 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
Proteomesi
  • UP000002311 Componenti: Chromosome IX

Organism-specific databases

EuPathDBiFungiDB:YIL097W
SGDiS000001359 FYV10

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Cytoplasm, Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002029701 – 516Protein FYV10Add BLAST516

Proteomic databases

MaxQBiP40492
PaxDbiP40492
PRIDEiP40492

Interactioni

Protein-protein interaction databases

BioGridi34894, 256 interactors
DIPiDIP-4148N
IntActiP40492, 6 interactors
MINTiP40492
STRINGi4932.YIL097W

Structurei

3D structure databases

ProteinModelPortaliP40492
SMRiP40492
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini187 – 245CTLHPROSITE-ProRule annotationAdd BLAST59

Sequence similaritiesi

Belongs to the FYV10 family.Curated

Phylogenomic databases

GeneTreeiENSGT00720000108841
HOGENOMiHOG000000964
InParanoidiP40492
KOiK18624
OMAiYAHHTKS
OrthoDBiEOG092C1P6J

Family and domain databases

InterProiView protein in InterPro
IPR024964 CTLH/CRA
IPR006595 CTLH_C
IPR027714 Fyv10/EMP
PANTHERiPTHR12170:SF2 PTHR12170:SF2, 1 hit
PfamiView protein in Pfam
PF10607 CLTH, 1 hit
SMARTiView protein in SMART
SM00668 CTLH, 1 hit
PROSITEiView protein in PROSITE
PS50897 CTLH, 1 hit

Sequencei

Sequence statusi: Complete.

P40492-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAEKSIFNEP DVDFHLKLNQ QLFHIPYELL SKRIKHTQAV INKETKSLHE
60 70 80 90 100
HTAALNQIFE HNDVEHDELA LAKITEMIRK VDHIERFLNT QIKSYCQILN
110 120 130 140 150
RIKKRLEFFH ELKDIKSQNS GTSHNGNNEG TRTKLIQWYQ SYTNILIGDY
160 170 180 190 200
LTRNNPIKYN SETKDHWNSG VVFLKQSQLD DLIDYDVLLE ANRISTSLLH
210 220 230 240 250
ERNLLPLISW INENKKTLTK KSSILEFQAR LQEYIELLKV DNYTDAIVCF
260 270 280 290 300
QRFLLPFVKS NFTDLKLASG LLIFIKYCND QKPTSSTSSG FDTEEIKSQS
310 320 330 340 350
LPMKKDRIFQ HFFHKSLPRI TSKPAVNTTD YDKSSLINLQ SGDFERYLNL
360 370 380 390 400
LDDQRWSVLN DLFLSDFYSM YGISQNDPLL IYLSLGISSL KTRDCLHPSD
410 420 430 440 450
DENGNQETET ATTAEKEVED LQLFTLHSLK RKNCPVCSET FKPITQALPF
460 470 480 490 500
AHHIQSQLFE NPILLPNGNV YDSKKLKKLA KTLKKQNLIS LNPGQIMDPV
510
DMKIFCESDS IKMYPT
Length:516
Mass (Da):59,894
Last modified:February 1, 1995 - v1
Checksum:i2EACCF8C6C314D56
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Z38125 Genomic DNA Translation: CAA86284.1
AY692905 Genomic DNA Translation: AAT92924.1
BK006942 Genomic DNA Translation: DAA08456.1
PIRiS48476
RefSeqiNP_012169.1, NM_001179445.1

Genome annotation databases

EnsemblFungiiYIL097W; YIL097W; YIL097W
GeneIDi854710
KEGGisce:YIL097W

Similar proteinsi

Entry informationi

Entry nameiFYV10_YEAST
AccessioniPrimary (citable) accession number: P40492
Secondary accession number(s): D6VVJ0
Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 1, 1995
Last sequence update: February 1, 1995
Last modified: May 23, 2018
This is version 129 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

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