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P40491 (FMC1_YEAST) Reviewed, UniProtKB/Swiss-Prot

Last modified June 11, 2014. Version 103. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (3) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
ATP synthase assembly factor FMC1, mitochondrial
Alternative name(s):
Formation of mitochondrial complexes protein 1
Gene names
Name:FMC1
Ordered Locus Names:YIL098C
OrganismSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) [Reference proteome]
Taxonomic identifier559292 [NCBI]
Taxonomic lineageEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces

Protein attributes

Sequence length155 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is further processed into a mature form.
Protein existenceEvidence at protein level

General annotation (Comments)

Function

Needed for the assembly of the mitochondrial F1-F0 complex at high temperature. Ref.4

Subcellular location

Mitochondrion Ref.4 Ref.5 Ref.6.

Miscellaneous

Present with 589 molecules/cell in log phase SD medium.

Sequence similarities

Belongs to the FMC1 family.

Ontologies

Keywords
   Biological processStress response
   Cellular componentMitochondrion
   DomainTransit peptide
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Biological_processmitochondrial proton-transporting ATP synthase complex assembly

Inferred from mutant phenotype Ref.4. Source: SGD

response to stress

Inferred from electronic annotation. Source: UniProtKB-KW

   Cellular_componentmitochondrial matrix

Inferred from direct assay Ref.4. Source: SGD

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Transit peptide1 – ?Mitochondrion Potential
Chain? – 155ATP synthase assembly factor FMC1, mitochondrialPRO_0000202969

Sequences

Sequence LengthMass (Da)Tools
P40491 [UniParc].

Last modified February 1, 1995. Version 1.
Checksum: EAE988BFACA1F330

FASTA15518,364
        10         20         30         40         50         60 
MDRPRTLRTY RGLIRAILKY ERPSKIVNWG NLRKAMITKL EYAKKQNQRD SHENINRQLE 

        70         80         90        100        110        120 
KWKKLDPVSD RSLNLFIADS KSLRSILQND IKWEKKVAQG QNVDEIFEHA LDIIKFLDNQ 

       130        140        150 
REYEELVDRY NPGNKLTQDE KVKRTANVVG LDVPT 

« Hide

References

« Hide 'large scale' references
[1]"The nucleotide sequence of Saccharomyces cerevisiae chromosome IX."
Churcher C.M., Bowman S., Badcock K., Bankier A.T., Brown D., Chillingworth T., Connor R., Devlin K., Gentles S., Hamlin N., Harris D.E., Horsnell T., Hunt S., Jagels K., Jones M., Lye G., Moule S., Odell C. expand/collapse author list , Pearson D., Rajandream M.A., Rice P., Rowley N., Skelton J., Smith V., Walsh S.V., Whitehead S., Barrell B.G.
Nature 387:84-87(1997) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 204508 / S288c.
[2]"The reference genome sequence of Saccharomyces cerevisiae: Then and now."
Engel S.R., Dietrich F.S., Fisk D.G., Binkley G., Balakrishnan R., Costanzo M.C., Dwight S.S., Hitz B.C., Karra K., Nash R.S., Weng S., Wong E.D., Lloyd P., Skrzypek M.S., Miyasato S.R., Simison M., Cherry J.M.
G3 (Bethesda) 4:389-398(2014) [PubMed] [Europe PMC] [Abstract]
Cited for: GENOME REANNOTATION.
Strain: ATCC 204508 / S288c.
[3]"Approaching a complete repository of sequence-verified protein-encoding clones for Saccharomyces cerevisiae."
Hu Y., Rolfs A., Bhullar B., Murthy T.V.S., Zhu C., Berger M.F., Camargo A.A., Kelley F., McCarron S., Jepson D., Richardson A., Raphael J., Moreira D., Taycher E., Zuo D., Mohr S., Kane M.F., Williamson J. expand/collapse author list , Simpson A.J.G., Bulyk M.L., Harlow E., Marsischky G., Kolodner R.D., LaBaer J.
Genome Res. 17:536-543(2007) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
Strain: ATCC 204508 / S288c.
[4]"Identification of a nuclear gene (FMC1) required for the assembly/stability of yeast mitochondrial F(1)-ATPase in heat stress conditions."
Lefebvre-Legendre L., Vaillier J., Benabdelhak H., Velours J., Slonimski P.P., di Rago J.-P.
J. Biol. Chem. 276:6789-6796(2001) [PubMed] [Europe PMC] [Abstract]
Cited for: FUNCTION, SUBCELLULAR LOCATION.
[5]"Global analysis of protein localization in budding yeast."
Huh W.-K., Falvo J.V., Gerke L.C., Carroll A.S., Howson R.W., Weissman J.S., O'Shea E.K.
Nature 425:686-691(2003) [PubMed] [Europe PMC] [Abstract]
Cited for: SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS].
[6]"The proteome of Saccharomyces cerevisiae mitochondria."
Sickmann A., Reinders J., Wagner Y., Joppich C., Zahedi R.P., Meyer H.E., Schoenfisch B., Perschil I., Chacinska A., Guiard B., Rehling P., Pfanner N., Meisinger C.
Proc. Natl. Acad. Sci. U.S.A. 100:13207-13212(2003) [PubMed] [Europe PMC] [Abstract]
Cited for: SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS].
Strain: ATCC 76625 / YPH499.
[7]"Global analysis of protein expression in yeast."
Ghaemmaghami S., Huh W.-K., Bower K., Howson R.W., Belle A., Dephoure N., O'Shea E.K., Weissman J.S.
Nature 425:737-741(2003) [PubMed] [Europe PMC] [Abstract]
Cited for: LEVEL OF PROTEIN EXPRESSION [LARGE SCALE ANALYSIS].
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
Z38125 Genomic DNA. Translation: CAA86283.1.
AY558072 Genomic DNA. Translation: AAS56398.1.
BK006942 Genomic DNA. Translation: DAA08455.1.
PIRS48475.
RefSeqNP_012168.3. NM_001179446.3.

3D structure databases

ProteinModelPortalP40491.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

BioGrid34893. 98 interactions.
DIPDIP-5652N.
IntActP40491. 1 interaction.
MINTMINT-502860.
STRING4932.YIL098C.

Proteomic databases

MaxQBP40491.
PaxDbP40491.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblFungiYIL098C; YIL098C; YIL098C.
GeneID854709.
KEGGsce:YIL098C.

Organism-specific databases

CYGDYIL098c.
SGDS000001360. FMC1.

Phylogenomic databases

eggNOGNOG80151.
HOGENOMHOG000000963.
KOK18191.
OMADSHENIN.
OrthoDBEOG7HTHWD.

Enzyme and pathway databases

BioCycYEAST:G3O-31357-MONOMER.

Gene expression databases

GenevestigatorP40491.

Family and domain databases

ProtoNetSearch...

Other

NextBio977369.

Entry information

Entry nameFMC1_YEAST
AccessionPrimary (citable) accession number: P40491
Secondary accession number(s): D6VVI9
Entry history
Integrated into UniProtKB/Swiss-Prot: February 1, 1995
Last sequence update: February 1, 1995
Last modified: June 11, 2014
This is version 103 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Relevant documents

Yeast chromosome IX

Yeast (Saccharomyces cerevisiae) chromosome IX: entries and gene names

Yeast

Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD

SIMILARITY comments

Index of protein domains and families