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P40456

- ESL1_YEAST

UniProt

P40456 - ESL1_YEAST

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Protein

EST/SMG-like protein 1

Gene

ESL1

Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed - Annotation score: 2 out of 5- Experimental evidence at protein leveli

Functioni

May be involved in the regulation of gene expression responses of environment-sensing pathways.1 Publication

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-KW
Complete GO annotation...

Enzyme and pathway databases

BioCyciYEAST:G3O-31400-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
EST/SMG-like protein 11 Publication
Gene namesi
Name:ESL11 Publication
Ordered Locus Names:YIL151CImported
OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Taxonomic identifieri559292 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
ProteomesiUP000002311: Chromosome IX

Organism-specific databases

CYGDiYIL151c.
SGDiS000001413. ESL1.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 11181118EST/SMG-like protein 1PRO_0000202957Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei170 – 1701Phosphoserine1 Publication
Modified residuei190 – 1901Phosphoserine1 Publication

Keywords - PTMi

Phosphoprotein

Proteomic databases

MaxQBiP40456.
PaxDbiP40456.

Expressioni

Gene expression databases

GenevestigatoriP40456.

Interactioni

Protein-protein interaction databases

BioGridi34841. 25 interactions.
DIPiDIP-1904N.
IntActiP40456. 6 interactions.
MINTiMINT-388670.
STRINGi4932.YIL151C.

Structurei

3D structure databases

ProteinModelPortaliP40456.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini947 – 1087141PINcSequence AnalysisAdd
BLAST

Sequence similaritiesi

Contains 1 PINc domain.Sequence Analysis

Phylogenomic databases

eggNOGiNOG46869.
GeneTreeiENSGT00390000014294.
HOGENOMiHOG000142087.
InParanoidiP40456.
OrthoDBiEOG7RFTRM.

Family and domain databases

InterProiIPR002716. PIN_dom.
[Graphical view]
PfamiPF13638. PIN_4. 1 hit.
[Graphical view]
SMARTiSM00670. PINc. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P40456-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MVDLMVPAND DPSNETDYSR SNNNHTHIVS DMRPTSAAFL HQKRHSSSSH
60 70 80 90 100
NDTPESSFAK RRVPGIVDPV GKGFIDGITN SQISAQNTPS KTDDASRRPS
110 120 130 140 150
ISRKVMESTP QVKTSSIPTM DVPKSPYYVN RTMLARNMKV VSRDTYEDNA
160 170 180 190 200
NPQMRADEPL VASNGIYSNS QPQSQVTLSD IRRAPVVAAS PPPMIRQLPS
210 220 230 240 250
AQPNQTFIKK LQEIYKIIVV QETELQQRCL YLTTSQTTEL KSLWAIYRLN
260 270 280 290 300
TELIKNYINF IITALLTTQP INDLIMGQEI LDIYRIEKRL WVYGIITFLD
310 320 330 340 350
VLKNFSNFMD PEVCCQFIIY AFISVSNMLE DIPLKYSILW RQRLGDLSRM
360 370 380 390 400
AISLYPSGFI DWRLSAEYWY TESMKYIYGC GKLYYHIATV QQNSLEAFVN
410 420 430 440 450
LGKSVFCQDP FTPSQQTLQL LIENIYQSAF IDRSSGSANN NEIAHRNSQL
460 470 480 490 500
IDYLKHTEVM LLPSFLENMD LQHVVLMYFK DKFGKDFNGN DVFDTKDMFC
510 520 530 540 550
QNPESLRYYF RHAPAFAESQ LLQLIGFGNP KNPFALLFQL PKYLKLKKDK
560 570 580 590 600
REKKRSEATE TSSYTDPFDV QISSESYFQN IDALNSSFND IPTNLNIWLD
610 620 630 640 650
SLNHINMTSI QCSIHVLTKF LHAPLVVALP HFLTWLHFIV AILKKLEMVN
660 670 680 690 700
SKQVVAFWIH FLRRTMPWNS IVTLGNVLVC YMLDNLHPFL KKELEKFYSL
710 720 730 740 750
ELDDLIEYYN ENENLPEIWK CWGTLWFDAI KKCDVMEIPG VQDHLFFDSP
760 770 780 790 800
LDGIVFDEKD EVGEKFWMRS VRAVLLLKGI AKKFPDLGLK VSFQASVFCR
810 820 830 840 850
RNDIPPDYFL KNLTFKLDAY DEDNYNDNNE LDDLYDTIEI NEEIEAVNMD
860 870 880 890 900
PQATPNLSVV SGESIFEYTG YTRLAPDYHC FDKNGGFNSA FIYSQWSNVG
910 920 930 940 950
NGVTLDVSGE SIYDVANNNL SLHWEKIFFD KIAAASKGSD ENYNCTLYFV
960 970 980 990 1000
IDATSWLRHF AHIFKLAKNN TLKFAICLTT FQELRYLRGS KDDTVVEAAT
1010 1020 1030 1040 1050
RSVITIRQLY DEKKIIPMRF TGNIATHVEE NLEFEEQITW KTHVDEFVID
1060 1070 1080 1090 1100
AIAKLNQRFQ AERLTDENKN KGKEFAVLVT DDDNMNQKAK DRMIKTCNTK
1110
YLFSLGSKLG INSGLCTN
Length:1,118
Mass (Da):128,735
Last modified:February 1, 1995 - v1
Checksum:i4F80F3A5E95C6CC3
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Z38059 Genomic DNA. Translation: CAA86127.1.
BK006942 Genomic DNA. Translation: DAA08402.1.
PIRiS48383.
RefSeqiNP_012115.1. NM_001179499.1.

Genome annotation databases

EnsemblFungiiYIL151C; YIL151C; YIL151C.
GeneIDi854655.
KEGGisce:YIL151C.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Z38059 Genomic DNA. Translation: CAA86127.1 .
BK006942 Genomic DNA. Translation: DAA08402.1 .
PIRi S48383.
RefSeqi NP_012115.1. NM_001179499.1.

3D structure databases

ProteinModelPortali P40456.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

BioGridi 34841. 25 interactions.
DIPi DIP-1904N.
IntActi P40456. 6 interactions.
MINTi MINT-388670.
STRINGi 4932.YIL151C.

Proteomic databases

MaxQBi P40456.
PaxDbi P40456.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblFungii YIL151C ; YIL151C ; YIL151C .
GeneIDi 854655.
KEGGi sce:YIL151C.

Organism-specific databases

CYGDi YIL151c.
SGDi S000001413. ESL1.

Phylogenomic databases

eggNOGi NOG46869.
GeneTreei ENSGT00390000014294.
HOGENOMi HOG000142087.
InParanoidi P40456.
OrthoDBi EOG7RFTRM.

Enzyme and pathway databases

BioCyci YEAST:G3O-31400-MONOMER.

Miscellaneous databases

NextBioi 977214.

Gene expression databases

Genevestigatori P40456.

Family and domain databases

InterProi IPR002716. PIN_dom.
[Graphical view ]
Pfami PF13638. PIN_4. 1 hit.
[Graphical view ]
SMARTi SM00670. PINc. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 204508 / S288c.
  2. Cited for: GENOME REANNOTATION.
    Strain: ATCC 204508 / S288c.
  3. Cited for: LEVEL OF PROTEIN EXPRESSION [LARGE SCALE ANALYSIS].
  4. "A multidimensional chromatography technology for in-depth phosphoproteome analysis."
    Albuquerque C.P., Smolka M.B., Payne S.H., Bafna V., Eng J., Zhou H.
    Mol. Cell. Proteomics 7:1389-1396(2008) [PubMed] [Europe PMC] [Abstract]
    Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-170 AND SER-190, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
  5. "Global analysis of Cdk1 substrate phosphorylation sites provides insights into evolution."
    Holt L.J., Tuch B.B., Villen J., Johnson A.D., Gygi S.P., Morgan D.O.
    Science 325:1682-1686(2009) [PubMed] [Europe PMC] [Abstract]
    Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
  6. Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
  7. "Yeast hEST1A/B (SMG5/6)-like proteins contribute to environment-sensing adaptive gene expression responses."
    Lai X., Beilharz T., Au W.C., Hammet A., Preiss T., Basrai M.A., Heierhorst J.
    G3 (Bethesda) 3:1649-1659(2013) [PubMed] [Europe PMC] [Abstract]
    Cited for: FUNCTION.

Entry informationi

Entry nameiESL1_YEAST
AccessioniPrimary (citable) accession number: P40456
Secondary accession number(s): D6VVD6
Entry historyi
Integrated into UniProtKB/Swiss-Prot: February 1, 1995
Last sequence update: February 1, 1995
Last modified: November 26, 2014
This is version 95 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Miscellaneous

Present with 504 molecules/cell in log phase SD medium.1 Publication

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Yeast
    Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD
  3. Yeast chromosome IX
    Yeast (Saccharomyces cerevisiae) chromosome IX: entries and gene names

External Data

Dasty 3