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Protein

Uncharacterized transporter YIL166C

Gene

YIL166C

Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

  1. transporter activity Source: SGD

GO - Biological processi

  1. transmembrane transport Source: InterPro
  2. transport Source: SGD
Complete GO annotation...

Keywords - Biological processi

Transport

Enzyme and pathway databases

BioCyciYEAST:G3O-31411-MONOMER.

Protein family/group databases

TCDBi2.A.1.14.38. the major facilitator superfamily (mfs).

Names & Taxonomyi

Protein namesi
Recommended name:
Uncharacterized transporter YIL166C
Gene namesi
Ordered Locus Names:YIL166C
OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Taxonomic identifieri559292 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
ProteomesiUP000002311: Chromosome IX

Organism-specific databases

CYGDiYIL166c.
SGDiS000001428. YIL166C.

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Topological domaini1 – 7878ExtracellularSequence AnalysisAdd
BLAST
Transmembranei79 – 9921HelicalSequence AnalysisAdd
BLAST
Topological domaini100 – 11920CytoplasmicSequence AnalysisAdd
BLAST
Transmembranei120 – 14021HelicalSequence AnalysisAdd
BLAST
Topological domaini141 – 1477ExtracellularSequence Analysis
Transmembranei148 – 16821HelicalSequence AnalysisAdd
BLAST
Topological domaini169 – 1768CytoplasmicSequence Analysis
Transmembranei177 – 19721HelicalSequence AnalysisAdd
BLAST
Topological domaini198 – 20811ExtracellularSequence AnalysisAdd
BLAST
Transmembranei209 – 22921HelicalSequence AnalysisAdd
BLAST
Topological domaini230 – 24112CytoplasmicSequence AnalysisAdd
BLAST
Transmembranei242 – 26221HelicalSequence AnalysisAdd
BLAST
Topological domaini263 – 32664ExtracellularSequence AnalysisAdd
BLAST
Transmembranei327 – 34721HelicalSequence AnalysisAdd
BLAST
Topological domaini348 – 35912CytoplasmicSequence AnalysisAdd
BLAST
Transmembranei360 – 38021HelicalSequence AnalysisAdd
BLAST
Topological domaini381 – 3877ExtracellularSequence Analysis
Transmembranei388 – 40821HelicalSequence AnalysisAdd
BLAST
Topological domaini409 – 4168CytoplasmicSequence Analysis
Transmembranei417 – 43721HelicalSequence AnalysisAdd
BLAST
Topological domaini438 – 48245ExtracellularSequence AnalysisAdd
BLAST
Transmembranei483 – 50321HelicalSequence AnalysisAdd
BLAST
Topological domaini504 – 54239CytoplasmicSequence AnalysisAdd
BLAST

GO - Cellular componenti

  1. integral component of membrane Source: UniProtKB-KW
  2. membrane Source: SGD
Complete GO annotation...

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 542542Uncharacterized transporter YIL166CPRO_0000121373Add
BLAST

Expressioni

Gene expression databases

GenevestigatoriP40445.

Interactioni

Protein-protein interaction databases

BioGridi34827. 10 interactions.
DIPiDIP-8099N.
STRINGi4932.YIL166C.

Structurei

3D structure databases

ProteinModelPortaliP40445.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiCOG0477.
GeneTreeiENSGT00730000113008.
HOGENOMiHOG000178876.
InParanoidiP40445.
OMAiNICMAVA.
OrthoDBiEOG73BVND.

Family and domain databases

InterProiIPR011701. MFS.
IPR020846. MFS_dom.
[Graphical view]
PfamiPF07690. MFS_1. 1 hit.
[Graphical view]
SUPFAMiSSF103473. SSF103473. 1 hit.
PROSITEiPS50850. MFS. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P40445-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MSVQKEEYDI VEKAQLSVSA ESLTSDSESI SHNPFDDFHK AERWRKVYES
60 70 80 90 100
SGYEGLSKFD PEFTWTKDEE KKLVRKMDLK IFLWVFIMFA FLDLIRKNIA
110 120 130 140 150
RAVSDNFIVD LKMNTNDYNL GQTVYLVIFL ASELPGNLLS KRFGPERVIP
160 170 180 190 200
VQIVLWSVIC ITQAGLKNRG QFIATRCLLG MVQGGFIPDN ILYLSYYYTG
210 220 230 240 250
AELTFRLSFF WCAIPLFQIL GSLLASGIIE MRGIHNLAGW QYLFIIEGFL
260 270 280 290 300
SLSVGVASFY LMRRGPTQTG ESAFHKGKSL FTEYEEKIMV NRILRDDPSK
310 320 330 340 350
GDMSNRQPVT FKEILYTLTE FDLWPLFIQG ITAFISLQTV GSYLSLILKS
360 370 380 390 400
LNYSTFLSNI LAIPGQALLL INLPLAALLS RKLKEKSLCV GIANVWVLPF
410 420 430 440 450
IVSLVALPTD TNPWIKYILL TGILGLPYTH SILAGWVSEI SNSVRSRTVG
460 470 480 490 500
TALYNMSAQV GAIIASNMYR NDDKPYYTRG NKILLGFTCF NICMAVATKF
510 520 530 540
YYISRNKYKD RKWNSMTKEE QINYLDTTKD KGMKRLDYRF IH
Length:542
Mass (Da):61,898
Last modified:February 1, 1995 - v1
Checksum:iF20F9A91333A9F6D
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Z46921 Genomic DNA. Translation: CAA87026.1.
AY723832 Genomic DNA. Translation: AAU09749.1.
BK006942 Genomic DNA. Translation: DAA08387.1.
PIRiS50361.
RefSeqiNP_012100.1. NM_001179514.1.

Genome annotation databases

EnsemblFungiiYIL166C; YIL166C; YIL166C.
GeneIDi854640.
KEGGisce:YIL166C.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Z46921 Genomic DNA. Translation: CAA87026.1.
AY723832 Genomic DNA. Translation: AAU09749.1.
BK006942 Genomic DNA. Translation: DAA08387.1.
PIRiS50361.
RefSeqiNP_012100.1. NM_001179514.1.

3D structure databases

ProteinModelPortaliP40445.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi34827. 10 interactions.
DIPiDIP-8099N.
STRINGi4932.YIL166C.

Protein family/group databases

TCDBi2.A.1.14.38. the major facilitator superfamily (mfs).

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblFungiiYIL166C; YIL166C; YIL166C.
GeneIDi854640.
KEGGisce:YIL166C.

Organism-specific databases

CYGDiYIL166c.
SGDiS000001428. YIL166C.

Phylogenomic databases

eggNOGiCOG0477.
GeneTreeiENSGT00730000113008.
HOGENOMiHOG000178876.
InParanoidiP40445.
OMAiNICMAVA.
OrthoDBiEOG73BVND.

Enzyme and pathway databases

BioCyciYEAST:G3O-31411-MONOMER.

Miscellaneous databases

NextBioi977172.

Gene expression databases

GenevestigatoriP40445.

Family and domain databases

InterProiIPR011701. MFS.
IPR020846. MFS_dom.
[Graphical view]
PfamiPF07690. MFS_1. 1 hit.
[Graphical view]
SUPFAMiSSF103473. SSF103473. 1 hit.
PROSITEiPS50850. MFS. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 204508 / S288c.
  2. Cited for: GENOME REANNOTATION.
    Strain: ATCC 204508 / S288c.
  3. Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
    Strain: ATCC 204508 / S288c.
  4. "A global topology map of the Saccharomyces cerevisiae membrane proteome."
    Kim H., Melen K., Oesterberg M., von Heijne G.
    Proc. Natl. Acad. Sci. U.S.A. 103:11142-11147(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: TOPOLOGY [LARGE SCALE ANALYSIS].
    Strain: ATCC 208353 / W303-1A.

Entry informationi

Entry nameiYIQ6_YEAST
AccessioniPrimary (citable) accession number: P40445
Secondary accession number(s): D6VVC1
Entry historyi
Integrated into UniProtKB/Swiss-Prot: February 1, 1995
Last sequence update: February 1, 1995
Last modified: January 7, 2015
This is version 101 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Yeast
    Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD
  3. Yeast chromosome IX
    Yeast (Saccharomyces cerevisiae) chromosome IX: entries and gene names

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.