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P40445 (YIQ6_YEAST) Reviewed, UniProtKB/Swiss-Prot

Last modified April 3, 2013. Version 89. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (3) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Uncharacterized transporter YIL166C
Gene names
Ordered Locus Names:YIL166C
OrganismSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) [Reference proteome]
Taxonomic identifier559292 [NCBI]
Taxonomic lineageEukaryota › Fungi › Dikarya › Ascomycota › Saccharomycotina › Saccharomycetes › Saccharomycetales › Saccharomycetaceae › Saccharomyces ›

Protein attributes

Sequence length542 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

General annotation (Comments)

Subcellular location

Membrane; Multi-pass membrane protein.

Sequence similarities

Belongs to the major facilitator superfamily. Allantoate permease family.

Ontologies

Keywords
   Biological processTransport
   Cellular componentMembrane
   DomainTransmembrane
Transmembrane helix
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Biological_processtransmembrane transport

Inferred from electronic annotation. Source: InterPro

   Cellular_componentintegral to membrane

Inferred from sequence model PubMed 12192589. Source: SGD

   Molecular_functiontransporter activity

Inferred from sequence or structural similarity PubMed 8543057PubMed 9348664. Source: SGD

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 542542Uncharacterized transporter YIL166C
PRO_0000121373

Regions

Topological domain1 – 7878Extracellular Potential
Transmembrane79 – 9921Helical; Potential
Topological domain100 – 11920Cytoplasmic Potential
Transmembrane120 – 14021Helical; Potential
Topological domain141 – 1477Extracellular Potential
Transmembrane148 – 16821Helical; Potential
Topological domain169 – 1768Cytoplasmic Potential
Transmembrane177 – 19721Helical; Potential
Topological domain198 – 20811Extracellular Potential
Transmembrane209 – 22921Helical; Potential
Topological domain230 – 24112Cytoplasmic Potential
Transmembrane242 – 26221Helical; Potential
Topological domain263 – 32664Extracellular Potential
Transmembrane327 – 34721Helical; Potential
Topological domain348 – 35912Cytoplasmic Potential
Transmembrane360 – 38021Helical; Potential
Topological domain381 – 3877Extracellular Potential
Transmembrane388 – 40821Helical; Potential
Topological domain409 – 4168Cytoplasmic Potential
Transmembrane417 – 43721Helical; Potential
Topological domain438 – 48245Extracellular Potential
Transmembrane483 – 50321Helical; Potential
Topological domain504 – 54239Cytoplasmic Potential

Sequences

Sequence LengthMass (Da)Tools
P40445 [UniParc].

Last modified February 1, 1995. Version 1.
Checksum: F20F9A91333A9F6D

FASTA54261,898
        10         20         30         40         50         60 
MSVQKEEYDI VEKAQLSVSA ESLTSDSESI SHNPFDDFHK AERWRKVYES SGYEGLSKFD 

        70         80         90        100        110        120 
PEFTWTKDEE KKLVRKMDLK IFLWVFIMFA FLDLIRKNIA RAVSDNFIVD LKMNTNDYNL 

       130        140        150        160        170        180 
GQTVYLVIFL ASELPGNLLS KRFGPERVIP VQIVLWSVIC ITQAGLKNRG QFIATRCLLG 

       190        200        210        220        230        240 
MVQGGFIPDN ILYLSYYYTG AELTFRLSFF WCAIPLFQIL GSLLASGIIE MRGIHNLAGW 

       250        260        270        280        290        300 
QYLFIIEGFL SLSVGVASFY LMRRGPTQTG ESAFHKGKSL FTEYEEKIMV NRILRDDPSK 

       310        320        330        340        350        360 
GDMSNRQPVT FKEILYTLTE FDLWPLFIQG ITAFISLQTV GSYLSLILKS LNYSTFLSNI 

       370        380        390        400        410        420 
LAIPGQALLL INLPLAALLS RKLKEKSLCV GIANVWVLPF IVSLVALPTD TNPWIKYILL 

       430        440        450        460        470        480 
TGILGLPYTH SILAGWVSEI SNSVRSRTVG TALYNMSAQV GAIIASNMYR NDDKPYYTRG 

       490        500        510        520        530        540 
NKILLGFTCF NICMAVATKF YYISRNKYKD RKWNSMTKEE QINYLDTTKD KGMKRLDYRF 


IH

« Hide

References

« Hide 'large scale' references
[1]"The nucleotide sequence of Saccharomyces cerevisiae chromosome IX."
Churcher C.M., Bowman S., Badcock K., Bankier A.T., Brown D., Chillingworth T., Connor R., Devlin K., Gentles S., Hamlin N., Harris D.E., Horsnell T., Hunt S., Jagels K., Jones M., Lye G., Moule S., Odell C. expand/collapse author list , Pearson D., Rajandream M.A., Rice P., Rowley N., Skelton J., Smith V., Walsh S.V., Whitehead S., Barrell B.G.
Nature 387:84-87(1997) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 204511 / S288c / AB972.
[2]Saccharomyces Genome Database
Submitted (DEC-2009) to the EMBL/GenBank/DDBJ databases
Cited for: GENOME REANNOTATION.
Strain: ATCC 204508 / S288c.
[3]"Approaching a complete repository of sequence-verified protein-encoding clones for Saccharomyces cerevisiae."
Hu Y., Rolfs A., Bhullar B., Murthy T.V.S., Zhu C., Berger M.F., Camargo A.A., Kelley F., McCarron S., Jepson D., Richardson A., Raphael J., Moreira D., Taycher E., Zuo D., Mohr S., Kane M.F., Williamson J. expand/collapse author list , Simpson A.J.G., Bulyk M.L., Harlow E., Marsischky G., Kolodner R.D., LaBaer J.
Genome Res. 17:536-543(2007) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
Strain: ATCC 204508 / S288c.
[4]"A global topology map of the Saccharomyces cerevisiae membrane proteome."
Kim H., Melen K., Oesterberg M., von Heijne G.
Proc. Natl. Acad. Sci. U.S.A. 103:11142-11147(2006) [PubMed] [Europe PMC] [Abstract]
Cited for: TOPOLOGY [LARGE SCALE ANALYSIS].
Strain: ATCC 208353 / W303-1A.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		Z46921 Genomic DNA. Translation: CAA87026.1.
AY723832 Genomic DNA. Translation: AAU09749.1.
BK006942 Genomic DNA. Translation: DAA08387.1.
PIRS50361.
RefSeqNP_012100.1. NM_001179514.1.

3D structure databases

ProteinModelPortalP40445.
ModBaseSearch...

Protein-protein interaction databases

DIPDIP-8099N.
STRING4932.YIL166C.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblFungiYIL166C; YIL166C; YIL166C.
GeneID854640.
KEGGsce:YIL166C.

Organism-specific databases

CYGDYIL166c.
SGDS000001428. YIL166C.

Phylogenomic databases

eggNOGCOG0477.
GeneTreeENSGT00620000088258.
HOGENOMHOG000178876.
OMAHAIIVAM.
OrthoDBEOG447K2M.

Gene expression databases

GenevestigatorP40445.
GermOnlineYIL166C. Saccharomyces cerevisiae.

Family and domain databases

InterProIPR011701. MFS.
IPR020846. MFS_dom.
IPR016196. MFS_dom_general_subst_transpt.
[Graphical view]
PfamPF07690. MFS_1. 1 hit.
[Graphical view]
SUPFAMSSF103473. MFS_gen_substrate_transporter. 1 hit.
PROSITEPS50850. MFS. 1 hit.
[Graphical view]
ProtoNetSearch...

Other

NextBio977172.

Entry information

Entry nameYIQ6_YEAST
AccessionPrimary (citable) accession number: P40445
Secondary accession number(s): D6VVC1
Entry history
Integrated into UniProtKB/Swiss-Prot: February 1, 1995
Last sequence update: February 1, 1995
Last modified: April 3, 2013
This is version 89 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Relevant documents

Yeast

Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD

Yeast chromosome IX

Yeast (Saccharomyces cerevisiae) chromosome IX: entries and gene names

SIMILARITY comments

Index of protein domains and families

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