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P40441

- HXT12_YEAST

UniProt

P40441 - HXT12_YEAST

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Protein
Putative hexose transporter 12
Gene
HXT12, YIL170W, YI9402.06B
Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed - Annotation score: 2 out of 5 - Protein uncertaini

Functioni

Probable glucose transporter.

GO - Molecular functioni

  1. substrate-specific transmembrane transporter activity Source: InterPro

GO - Biological processi

  1. carbohydrate transport Source: UniProtKB-KW
Complete GO annotation...

Keywords - Biological processi

Sugar transport, Transport

Names & Taxonomyi

Protein namesi
Recommended name:
Putative hexose transporter 12
Gene namesi
Name:HXT12
Ordered Locus Names:YIL170W
ORF Names:YI9402.06B
OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Taxonomic identifieri559292 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
ProteomesiUP000002311: Chromosome IX

Organism-specific databases

CYGDiYIL170w.
SGDiS000001432. HXT12.

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Topological domaini1 – 22Cytoplasmic Reviewed prediction
Transmembranei3 – 2321Helical; Name=1; Reviewed prediction
Add
BLAST
Topological domaini24 – 296Extracellular Reviewed prediction
Transmembranei30 – 5021Helical; Name=2; Reviewed prediction
Add
BLAST
Topological domaini51 – 6010Cytoplasmic Reviewed prediction
Transmembranei61 – 8121Helical; Name=3; Reviewed prediction
Add
BLAST
Topological domaini82 – 876Extracellular Reviewed prediction
Transmembranei88 – 10821Helical; Name=4; Reviewed prediction
Add
BLAST
Topological domaini109 – 12214Cytoplasmic Reviewed prediction
Add
BLAST
Transmembranei123 – 14321Helical; Name=5; Reviewed prediction
Add
BLAST
Topological domaini144 – 247104Extracellular Reviewed prediction
Add
BLAST
Transmembranei248 – 26821Helical; Name=6; Reviewed prediction
Add
BLAST
Topological domaini269 – 2746Cytoplasmic Reviewed prediction
Transmembranei275 – 29521Helical; Name=7; Reviewed prediction
Add
BLAST
Topological domaini296 – 31924Extracellular Reviewed prediction
Add
BLAST
Transmembranei320 – 34021Helical; Name=8; Reviewed prediction
Add
BLAST
Topological domaini341 – 35313Cytoplasmic Reviewed prediction
Add
BLAST
Transmembranei354 – 37421Helical; Name=9; Reviewed prediction
Add
BLAST
Topological domaini375 – 3795Extracellular Reviewed prediction
Transmembranei380 – 40021Helical; Name=10; Reviewed prediction
Add
BLAST
Topological domaini401 – 45757Cytoplasmic Reviewed prediction
Add
BLAST

GO - Cellular componenti

  1. integral component of membrane Source: UniProtKB-KW
Complete GO annotation...

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 457457Putative hexose transporter 12
PRO_0000050408Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Glycosylationi194 – 1941N-linked (GlcNAc...) Reviewed prediction

Keywords - PTMi

Glycoprotein

Expressioni

Gene expression databases

GenevestigatoriP40441.

Interactioni

Protein-protein interaction databases

DIPiDIP-7421N.
IntActiP40441. 2 interactions.
MINTiMINT-1361084.
STRINGi4932.YOL156W.

Structurei

3D structure databases

ProteinModelPortaliP40441.
SMRiP40441. Positions 1-416.

Family & Domainsi

Sequence similaritiesi

Keywords - Domaini

Repeat, Transmembrane, Transmembrane helix

Phylogenomic databases

OrthoDBiEOG73JM4H.

Family and domain databases

InterProiIPR020846. MFS_dom.
IPR016196. MFS_dom_general_subst_transpt.
IPR005828. Sub_transporter.
IPR003663. Sugar/inositol_transpt.
IPR005829. Sugar_transporter_CS.
[Graphical view]
PfamiPF00083. Sugar_tr. 1 hit.
[Graphical view]
PRINTSiPR00171. SUGRTRNSPORT.
SUPFAMiSSF103473. SSF103473. 1 hit.
TIGRFAMsiTIGR00879. SP. 1 hit.
PROSITEiPS50850. MFS. 1 hit.
PS00216. SUGAR_TRANSPORT_1. 1 hit.
PS00217. SUGAR_TRANSPORT_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P40441-1 [UniParc]FASTAAdd to Basket

« Hide

MGLIVSIFNI GCAIGGIVLS KVGDIYGRRI GLITVTAIYV VGILIQITSI    50
NKWYQYFIGR IISGIGVGGI AVLSPMLISE VAPKHIRGTL VQLYQLMGTM 100
GIFLGYCTNY GTKNYHNATQ WRVGLGLCFA WATFMVSGMM FVPESPRYLI 150
EVGKDEEAKH SLSKSNKVSV DDPALLAEYD TIKAGIEIEK LAGNASWSEL 200
LSTKTKVFQR VLMGVIIQSL QQLTGDNYFF YYGTTIFKSV GLKDSFQTSI 250
IIGVVNFFSS FIAVYTIERF GRRTCLLWGA ASMLCCFAVF ASVGVTKLWP 300
QGSSHQDITS QGAGNCMIVF TMFFIFSFAT TWAGGCFVIV SETFPLRAKS 350
RGMAIATAAN WMWGFLISFF TPFITGAINF YYGYVFLGCL VFAYFYVFFF 400
VPETKGLTLE EVNTMWLEGV PAWKSASWVP PERRTADYDA DAIDHDNRPI 450
YKRFFSS 457
Length:457
Mass (Da):50,830
Last modified:February 1, 1995 - v1
Checksum:iFBEE8186BAC88B88
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
Z46881 Genomic DNA. Translation: CAA87022.1.
BK006942 Genomic DNA. No translation available.
PIRiS50357.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
Z46881 Genomic DNA. Translation: CAA87022.1 .
BK006942 Genomic DNA. No translation available.
PIRi S50357.

3D structure databases

ProteinModelPortali P40441.
SMRi P40441. Positions 1-416.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

DIPi DIP-7421N.
IntActi P40441. 2 interactions.
MINTi MINT-1361084.
STRINGi 4932.YOL156W.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Organism-specific databases

CYGDi YIL170w.
SGDi S000001432. HXT12.

Phylogenomic databases

OrthoDBi EOG73JM4H.

Gene expression databases

Genevestigatori P40441.

Family and domain databases

InterProi IPR020846. MFS_dom.
IPR016196. MFS_dom_general_subst_transpt.
IPR005828. Sub_transporter.
IPR003663. Sugar/inositol_transpt.
IPR005829. Sugar_transporter_CS.
[Graphical view ]
Pfami PF00083. Sugar_tr. 1 hit.
[Graphical view ]
PRINTSi PR00171. SUGRTRNSPORT.
SUPFAMi SSF103473. SSF103473. 1 hit.
TIGRFAMsi TIGR00879. SP. 1 hit.
PROSITEi PS50850. MFS. 1 hit.
PS00216. SUGAR_TRANSPORT_1. 1 hit.
PS00217. SUGAR_TRANSPORT_2. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 204508 / S288c.
  2. Cited for: GENOME REANNOTATION.
    Strain: ATCC 204508 / S288c.

Entry informationi

Entry nameiHXT12_YEAST
AccessioniPrimary (citable) accession number: P40441
Entry historyi
Integrated into UniProtKB/Swiss-Prot: February 1, 1995
Last sequence update: February 1, 1995
Last modified: May 14, 2014
This is version 102 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Caution

Could be the product of a pseudogene. YIL171W and YIL170W represent the N- and C-terminal of a putative transporter.

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Yeast
    Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD
  3. Yeast chromosome IX
    Yeast (Saccharomyces cerevisiae) chromosome IX: entries and gene names

External Data

Dasty 3

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