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Protein

Putative hexose transporter 12

Gene

HXT12

Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed-Annotation score: -Protein uncertaini

Functioni

Probable glucose transporter.

Caution

Could be the product of a pseudogene unlikely to encode a functional protein. YIL171W and YIL170W represent the N- and C-terminal of a putative transporter. Because of that it is not part of the S.cerevisiae S288c complete/reference proteome set.1 Publication

GO - Molecular functioni

Keywordsi

Biological processSugar transport, Transport

Names & Taxonomyi

Protein namesi
Recommended name:
Putative hexose transporter 12
Gene namesi
Name:HXT12
Ordered Locus Names:YIL170W
ORF Names:YI9402.06B
OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Taxonomic identifieri559292 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces

Organism-specific databases

SGDiS000001432 HXT12

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Topological domaini1 – 2CytoplasmicSequence analysis2
Transmembranei3 – 23Helical; Name=1Sequence analysisAdd BLAST21
Topological domaini24 – 29ExtracellularSequence analysis6
Transmembranei30 – 50Helical; Name=2Sequence analysisAdd BLAST21
Topological domaini51 – 60CytoplasmicSequence analysis10
Transmembranei61 – 81Helical; Name=3Sequence analysisAdd BLAST21
Topological domaini82 – 87ExtracellularSequence analysis6
Transmembranei88 – 108Helical; Name=4Sequence analysisAdd BLAST21
Topological domaini109 – 122CytoplasmicSequence analysisAdd BLAST14
Transmembranei123 – 143Helical; Name=5Sequence analysisAdd BLAST21
Topological domaini144 – 247ExtracellularSequence analysisAdd BLAST104
Transmembranei248 – 268Helical; Name=6Sequence analysisAdd BLAST21
Topological domaini269 – 274CytoplasmicSequence analysis6
Transmembranei275 – 295Helical; Name=7Sequence analysisAdd BLAST21
Topological domaini296 – 319ExtracellularSequence analysisAdd BLAST24
Transmembranei320 – 340Helical; Name=8Sequence analysisAdd BLAST21
Topological domaini341 – 353CytoplasmicSequence analysisAdd BLAST13
Transmembranei354 – 374Helical; Name=9Sequence analysisAdd BLAST21
Topological domaini375 – 379ExtracellularSequence analysis5
Transmembranei380 – 400Helical; Name=10Sequence analysisAdd BLAST21
Topological domaini401 – 457CytoplasmicSequence analysisAdd BLAST57

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000504081 – 457Putative hexose transporter 12Add BLAST457

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Glycosylationi194N-linked (GlcNAc...) asparagineSequence analysis1

Keywords - PTMi

Glycoprotein

Proteomic databases

PRIDEiP40441

Interactioni

Protein-protein interaction databases

DIPiDIP-7421N
IntActiP40441, 2 interactors
MINTiP40441

Structurei

3D structure databases

ProteinModelPortaliP40441
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Keywords - Domaini

Repeat, Transmembrane, Transmembrane helix

Phylogenomic databases

InParanoidiP40441
OrthoDBiEOG092C1Q5W

Family and domain databases

CDDicd06174 MFS, 1 hit
InterProiView protein in InterPro
IPR020846 MFS_dom
IPR005828 MFS_sugar_transport-like
IPR036259 MFS_trans_sf
IPR003663 Sugar/inositol_transpt
IPR005829 Sugar_transporter_CS
PfamiView protein in Pfam
PF00083 Sugar_tr, 1 hit
PRINTSiPR00171 SUGRTRNSPORT
SUPFAMiSSF103473 SSF103473, 1 hit
TIGRFAMsiTIGR00879 SP, 1 hit
PROSITEiView protein in PROSITE
PS50850 MFS, 1 hit
PS00216 SUGAR_TRANSPORT_1, 1 hit
PS00217 SUGAR_TRANSPORT_2, 1 hit

Sequencei

Sequence statusi: Complete.

P40441-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGLIVSIFNI GCAIGGIVLS KVGDIYGRRI GLITVTAIYV VGILIQITSI
60 70 80 90 100
NKWYQYFIGR IISGIGVGGI AVLSPMLISE VAPKHIRGTL VQLYQLMGTM
110 120 130 140 150
GIFLGYCTNY GTKNYHNATQ WRVGLGLCFA WATFMVSGMM FVPESPRYLI
160 170 180 190 200
EVGKDEEAKH SLSKSNKVSV DDPALLAEYD TIKAGIEIEK LAGNASWSEL
210 220 230 240 250
LSTKTKVFQR VLMGVIIQSL QQLTGDNYFF YYGTTIFKSV GLKDSFQTSI
260 270 280 290 300
IIGVVNFFSS FIAVYTIERF GRRTCLLWGA ASMLCCFAVF ASVGVTKLWP
310 320 330 340 350
QGSSHQDITS QGAGNCMIVF TMFFIFSFAT TWAGGCFVIV SETFPLRAKS
360 370 380 390 400
RGMAIATAAN WMWGFLISFF TPFITGAINF YYGYVFLGCL VFAYFYVFFF
410 420 430 440 450
VPETKGLTLE EVNTMWLEGV PAWKSASWVP PERRTADYDA DAIDHDNRPI

YKRFFSS
Length:457
Mass (Da):50,830
Last modified:February 1, 1995 - v1
Checksum:iFBEE8186BAC88B88
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Z46881 Genomic DNA Translation: CAA87022.1
PIRiS50357

Similar proteinsi

Entry informationi

Entry nameiHXT12_YEAST
AccessioniPrimary (citable) accession number: P40441
Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 1, 1995
Last sequence update: February 1, 1995
Last modified: April 25, 2018
This is version 124 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

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