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Chem.814493-4501ACETYLATION [LARGE SCALE ANALYSIS] AT ALA-2CLEAVAGE OF INITIATOR METHIONINE [LARGE SCALE ANALYSIS]IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]Lysine acetylation targets protein complexes and co-regulates major cellular functions.Choudhary C.Kumar C.Gnad F.Nielsen M.L.Rehman M.Walther T.C.Olsen J.V.Mann M.doi:10.1126/science.11753712009Science325834-840ACETYLATION [LARGE SCALE ANALYSIS] AT LYS-191IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]Initial characterization of the human central proteome.Burkard T.R.Planyavsky M.Kaupe I.Breitwieser F.P.Buerckstuemmer T.Bennett K.L.Superti-Furga G.Colinge J.doi:10.1186/1752-0509-5-172011BMC Syst. Biol.517IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]Heterotrimeric GAIT complex drives transcript-selective translation inhibition in murine macrophages.Arif A.Chatterjee P.Moodt R.A.Fox P.L.doi:10.1128/mcb.01168-122012Mol. Cell. 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U.S.A.10912449-12454ACETYLATION [LARGE SCALE ANALYSIS] AT ALA-2CLEAVAGE OF INITIATOR METHIONINE [LARGE SCALE ANALYSIS]IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]A new system for naming ribosomal proteins.Ban N.Beckmann R.Cate J.H.D.Dinman J.D.Dragon F.Ellis S.R.Lafontaine D.L.J.Lindahl L.Liljas A.Lipton J.M.McAlear M.A.Moore P.B.Noller H.F.Ortega J.Panse V.G.Ramakrishnan V.Spahn C.M.T.Steitz T.A.Tchorzewski M.Tollervey D.Warren A.J.Williamson J.R.Wilson D.Yonath A.Yusupov M.doi:10.1016/j.sbi.2014.01.0022014Curr. Opin. Struct. Biol.24165-169NOMENCLATUREBiochemical and cellular analysis of Ogden syndrome reveals downstream Nt-acetylation defects.Myklebust L.M.Van Damme P.Stoeve S.I.Doerfel M.J.Abboud A.Kalvik T.V.Grauffel C.Jonckheere V.Wu Y.Swensen J.Kaasa H.Liszczak G.Marmorstein R.Reuter N.Lyon G.J.Gevaert K.Arnesen T.doi:10.1093/hmg/ddu6112015Hum. Mol. 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Commun.113542STRUCTURE BY ELECTRON MICROSCOPY (3.09 ANGSTROMS)LO=1-2035.00CO=1-2033.50AO=1-2033.60LO=1-2033.60I=1-2033.902I=1-2034.502I=1-2033.902I=1-2033.09V=1-2033.13V=1-2033.23V=1-2033.13V=1-2033.10P=5-1993.90P=5-1993.40AO=5-1993.50P=5-1993.90AO=5-1993.10P=5-1993.70P=5-1992.90LO=3-2033.84P=1-2032.80LO=3-2033.20LO=1-2033.00LO=1-2033.50LO=1-2032.80LO=3-2033.00LO=1-2033.10LO=1-2032.90LO=1-2032.70LO=1-2033.00LO=1-2032.60LO=1-2033.10LO=1-2033.30LO=1-2032.72LO=1-2032.20I=1-2033.00LO/MO=1-2032.70LO=1-2032.50LO=1-2031.67I=1-2032.85L7=1-2032.76L7=1-2032.89L7=1-2032.88L7=1-2032.81L7=1-2032.82L7=1-2032.47L7=1-2032.50L7=1-2032.59L7=1-2032.67L7=1-2033.04L7=1-2032.91L7=1-2032.67L7=1-2032.53L7=1-2032.89L7=1-2032.62L7=1-2032.55L7=1-2032.75L7=1-2032.63L7=1-2032.55L7=1-2032.76L7=1-2032.58L7=1-2032.48L7=1-2032.65L7=1-2032.29LO=1-2032.64LO=3-2032.54LO=1-2032.94LO=1-2032.80LO=1-2031.67LO=1-2032.80V=1-2033.00V=1-2033.30V=1-2033.20V=1-2033.00V=1-2033.20V=1-2033.20V=1-2034.30V=1-2033.20V=1-2033.30V=1-2033.50V=1-2032.50T=1-2032.26T=1-2032.42T=1-2032.67T=1-203546GAIT complex60S cytosolic large ribosomal subunit60S cytosolic large ribosomal subunit, testis-specific variant60S cytosolic large ribosomal subunit, striated muscle variant109(S)-3-phenyllactic acidAnisomycinPuromycin1 site, 1 O-linked glycan (1 site)122 antibodies from 23 providershumanRPL13ALow tissue specificitygeneEukaryotaL13a-mediated translational silencing of Ceruloplasmin expressionPeptide chain elongationSRP-dependent cotranslational protein targeting to membraneViral mRNA TranslationSelenocysteine synthesisMajor pathway of rRNA processing in the nucleolus and cytosolFormation of a pool of free 40S subunitsGTP hydrolysis and joining of the 60S ribosomal subunitEukaryotic Translation TerminationRegulation of expression of SLITs and ROBOsResponse of EIF2AK4 (GCN2) to amino acid deficiencyNonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)583 hits in 1149 CRISPR screenshumanTbioProteinExpressed in left ovary and 95 other cell types or tissuesbaseline and differentialRibosomal_L13Ribosomal protein L13Ribosomal_uL13Ribosomal_uL13Ribosomal_uL13_CSRibosomal_uL13_euk/arcRibosomal_uL13_sfL13_A_E60S RIBOSOMAL PROTEIN L13ARIBOSOMAL PROTEIN L13Ribosomal_L13Ribosomal protein L13RIBOSOMAL_L13HSLarge ribosomal subunit protein uL1323 kDa highly basic protein60S ribosomal protein L13aRPL13AAssociated with ribosomes but is not required for canonical ribosome function and has extra-ribosomal functions (PubMed:14567916, PubMed:17218275, PubMed:23636399, PubMed:32669547). Component of the GAIT (gamma interferon-activated inhibitor of translation) complex which mediates interferon-gamma-induced transcript-selective translation inhibition in inflammation processes (PubMed:23071094). Upon interferon-gamma activation and subsequent phosphorylation dissociates from the ribosome and assembles into the GAIT complex which binds to stem loop-containing GAIT elements in the 3'-UTR of diverse inflammatory mRNAs (such as ceruplasmin) and suppresses their translation (PubMed:23071094). In the GAIT complex interacts with m7G cap-bound eIF4G at or near the eIF3-binding site and blocks the recruitment of the 43S ribosomal complex (PubMed:23071094). Involved in methylation of rRNA (PubMed:17921318).Component of the 60S ribosome (PubMed:14567916, PubMed:12962325, PubMed:23636399, PubMed:32669547). Component of the GAIT complex (PubMed:15479637). Interacts with EIF4G1 (PubMed:17218275).Phosphorylation at Ser-77 upon interferon-gamma treatment in monocytes involves a DAPK1-DAPK3 kinase cascade and is causing release from the ribosome, association with the GAIT complex and subsequent involvement in transcript-selective translation inhibition.Citrullinated by PADI4.Belongs to the universal ribosomal protein uL13 family.Removed1Large ribosomal subunit protein uL13234462203N-acetylalanineCitrulline59Phosphoserine; by ZIPK/DAPK377Citrulline140N6-acetyllysine191Loss of interferon-gamma induced phosphorylation.A2007-01-23223577e1f60ddc904f1a2dce137a8920e880f0MAEVQVLVLDGRGHLLGRLAAIVAKQVLLGRKVVVVRCEGINISGNFYRNKLKYLAFLRKRMNTNPSRGPYHFRAPSRIFWRTVRGMLPHKTKRGQAALDRLKVFDGIPPPYDKKKRMVVPAALKVVRLKPTRKFAYLGRLAHEVGWKYQAVTATLEEKRKEKAKIHYRKKKQLMRLRKQAEKNVEKKIDKYTEVLKTHGLLVtruetruetruetruetruetruetruetruetruetruetruetruetruetruetruetruetruetruetruetruetruetruetruetruetruetruetruetruetruetruetruetruetrue