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Protein

Proline-rich protein HUA1

Gene

HUA1

Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

May be involved in assembly and disassembly of the actin cytoskeleton.1 Publication

Enzyme and pathway databases

BioCyciYEAST:G3O-30935-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Proline-rich protein HUA1
Gene namesi
Name:HUA1
Ordered Locus Names:YGR268C
OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Taxonomic identifieri559292 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
Proteomesi
  • UP000002311 Componenti: Chromosome VII

Organism-specific databases

EuPathDBiFungiDB:YGR268C
SGDiS000003500 HUA1

Subcellular locationi

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Initiator methionineiRemovedCombined sources
ChainiPRO_00002028652 – 198Proline-rich protein HUA1Add BLAST197

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei2N-acetylserineCombined sources1
Cross-linki3Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin)1 Publication
Cross-linki18Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin)1 Publication

Keywords - PTMi

Acetylation, Isopeptide bond, Ubl conjugation

Proteomic databases

MaxQBiP40325
PaxDbiP40325
PRIDEiP40325

PTM databases

iPTMnetiP40325

Interactioni

Binary interactionsi

Show more details

Protein-protein interaction databases

BioGridi33518, 62 interactors
DIPiDIP-1987N
IntActiP40325, 25 interactors
MINTiP40325
STRINGi4932.YGR268C

Structurei

3D structure databases

ProteinModelPortaliP40325
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Compositional biasi27 – 92Pro-richAdd BLAST66

Sequence similaritiesi

Belongs to the HUA1 family.Curated

Phylogenomic databases

HOGENOMiHOG000000943
InParanoidiP40325
OMAiKNGKSCQ
OrthoDBiEOG092C5RRV

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

P40325-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSKDTHDDEL PSYEDVIKEE ERLQSQPPRP PRPAANLAQG HQSRPHQRPS
60 70 80 90 100
TMPATSSSQT YAHSHSYTPT SSQPRPPPRP QQNPSLPWTY PPRFYCSKCG
110 120 130 140 150
NTGYKLKNGR SCKSCWRRFA PQNNVVSAPT YYTNYTMPVY TNAWQGNRPL
160 170 180 190
YVQPGDPRLG GVLCGECRGS GRTRFLLDED ICPLCHGVGR IITQPQRY
Length:198
Mass (Da):22,435
Last modified:October 1, 1996 - v2
Checksum:i78029FD484168793
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Y07893 Genomic DNA Translation: CAA69199.1
Z73053 Genomic DNA Translation: CAA97298.1
AY558512 Genomic DNA Translation: AAS56838.1
X81072 Genomic DNA Translation: CAA56961.1
BK006941 Genomic DNA Translation: DAA08357.1
PIRiS64601
RefSeqiNP_011784.3, NM_001181397.3

Genome annotation databases

EnsemblFungiiYGR268C; YGR268C; YGR268C
GeneIDi853185
KEGGisce:YGR268C

Similar proteinsi

Entry informationi

Entry nameiHUA1_YEAST
AccessioniPrimary (citable) accession number: P40325
Secondary accession number(s): D6VV46
Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 1, 1995
Last sequence update: October 1, 1996
Last modified: April 25, 2018
This is version 125 of the entry and version 2 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome
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Main funding by: National Institutes of Health