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P40306

- PSB10_HUMAN

UniProt

P40306 - PSB10_HUMAN

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Protein
Proteasome subunit beta type-10
Gene
PSMB10, LMP10, MECL1
Organism
Homo sapiens (Human)
Status
Reviewed - Annotation score: 5 out of 5 - Experimental evidence at protein leveli

Functioni

The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity. This subunit is involved in antigen processing to generate class I binding peptides.

Catalytic activityi

Cleavage of peptide bonds with very broad specificity.

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sitei39 – 402Cleavage; by autocatalysis By similarity
Active sitei40 – 401Nucleophile By similarity

GO - Molecular functioni

  1. threonine-type endopeptidase activity Source: UniProtKB-KW

GO - Biological processi

  1. DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest Source: Reactome
  2. G1/S transition of mitotic cell cycle Source: Reactome
  3. RNA metabolic process Source: Reactome
  4. T cell proliferation Source: Ensembl
  5. anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process Source: Reactome
  6. antigen processing and presentation of exogenous peptide antigen via MHC class I Source: Reactome
  7. antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent Source: Reactome
  8. antigen processing and presentation of peptide antigen via MHC class I Source: Reactome
  9. apoptotic process Source: Reactome
  10. cell morphogenesis Source: Ensembl
  11. cellular nitrogen compound metabolic process Source: Reactome
  12. gene expression Source: Reactome
  13. humoral immune response Source: ProtInc
  14. mRNA metabolic process Source: Reactome
  15. mitotic cell cycle Source: Reactome
  16. negative regulation of apoptotic process Source: Reactome
  17. negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle Source: Reactome
  18. positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle Source: Reactome
  19. protein polyubiquitination Source: Reactome
  20. regulation of apoptotic process Source: Reactome
  21. regulation of cellular amino acid metabolic process Source: Reactome
  22. regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle Source: Reactome
  23. small molecule metabolic process Source: Reactome
  24. viral process Source: Reactome
Complete GO annotation...

Keywords - Molecular functioni

Hydrolase, Protease, Threonine protease

Keywords - Biological processi

Host-virus interaction

Enzyme and pathway databases

ReactomeiREACT_111056. Cross-presentation of soluble exogenous antigens (endosomes).
REACT_111178. ER-Phagosome pathway.
REACT_1156. Orc1 removal from chromatin.
REACT_118656. Activation of NF-kappaB in B cells.
REACT_1221. CDK-mediated phosphorylation and removal of Cdc6.
REACT_13464. Regulation of activated PAK-2p34 by proteasome mediated degradation.
REACT_13565. Regulation of ornithine decarboxylase (ODC).
REACT_150471. Separation of Sister Chromatids.
REACT_1614. Ubiquitin Mediated Degradation of Phosphorylated Cdc25A.
REACT_172638. Asymmetric localization of PCP proteins.
REACT_1949. CDT1 association with the CDC6:ORC:origin complex.
REACT_200766. degradation of AXIN.
REACT_200841. degradation of DVL.
REACT_20549. Autodegradation of the E3 ubiquitin ligase COP1.
REACT_25325. AUF1 (hnRNP D0) destabilizes mRNA.
REACT_4. Ubiquitin-dependent degradation of Cyclin D1.
REACT_6761. APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1.
REACT_6785. Autodegradation of Cdh1 by Cdh1:APC/C.
REACT_6821. SCF-beta-TrCP mediated degradation of Emi1.
REACT_6871. APC/C:Cdc20 mediated degradation of Securin.
REACT_75842. Antigen processing: Ubiquitination & Proteasome degradation.
REACT_9003. SCF(Skp2)-mediated degradation of p27/p21.
REACT_9031. Vpu mediated degradation of CD4.
REACT_9453. Vif-mediated degradation of APOBEC3G.

Protein family/group databases

MEROPSiT01.014.

Names & Taxonomyi

Protein namesi
Recommended name:
Proteasome subunit beta type-10 (EC:3.4.25.1)
Alternative name(s):
Low molecular mass protein 10
Macropain subunit MECl-1
Multicatalytic endopeptidase complex subunit MECl-1
Proteasome MECl-1
Proteasome subunit beta-2i
Gene namesi
Name:PSMB10
Synonyms:LMP10, MECL1
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
ProteomesiUP000005640: Chromosome 16

Organism-specific databases

HGNCiHGNC:9538. PSMB10.

Subcellular locationi

Cytoplasm By similarity. Nucleus By similarity

GO - Cellular componenti

  1. cytosol Source: Reactome
  2. nucleoplasm Source: Reactome
  3. proteasome complex Source: ProtInc
  4. proteasome core complex Source: UniProtKB
  5. spermatoproteasome complex Source: UniProtKB
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm, Nucleus, Proteasome

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA33883.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Propeptidei1 – 3939Removed in mature form By similarity
PRO_0000026651Add
BLAST
Chaini40 – 273234Proteasome subunit beta type-10
PRO_0000026652Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei1 – 11N-acetylmethionine1 Publication

Post-translational modificationi

Autocleaved. The resulting N-terminal Thr residue of the mature subunit is responsible for the nucleophile proteolytic activity By similarity.

Keywords - PTMi

Acetylation, Zymogen

Proteomic databases

MaxQBiP40306.
PaxDbiP40306.
PeptideAtlasiP40306.
PRIDEiP40306.

2D gel databases

OGPiP40306.
SWISS-2DPAGEP40306.

PTM databases

PhosphoSiteiP40306.

Expressioni

Developmental stagei

Highly expressed in immature dendritic cells (at protein level).1 Publication

Inductioni

Up-regulated by IFNG/IFN-gamma (at protein level). Up-regulated by IRF1. Up-regulated by TNF (at protein level). Up-regulated by tetrodotoxin (TTX) in glial cells. Up-regulated in Crohn's bowel disease (CD). Up-regulated by CD40L via the NFKB1 pathway in cancer cells.7 Publications

Gene expression databases

BgeeiP40306.
CleanExiHS_PSMB10.
GenevestigatoriP40306.

Organism-specific databases

HPAiHPA030225.

Interactioni

Subunit structurei

The 26S proteasome consists of a 20S proteasome core and two 19S regulatory subunits. The 20S proteasome core is composed of 28 subunits that are arranged in four stacked rings, resulting in a barrel-shaped structure. The two end rings are each formed by seven alpha subunits, and the two central rings are each formed by seven beta subunits. The catalytic chamber with the active sites is on the inside of the barrel. Component of the immunoproteasome, where it displaces the equivalent houskeeping subunit PSMB7. Component of the spermatoproteasome, a form of the proteasome specifically found in testis. Interacts with HIV-1 TAT protein.1 Publication

Protein-protein interaction databases

BioGridi111672. 17 interactions.
IntActiP40306. 7 interactions.
STRINGi9606.ENSP00000351314.

Structurei

3D structure databases

ProteinModelPortaliP40306.
SMRiP40306. Positions 40-258.

Family & Domainsi

Sequence similaritiesi

Belongs to the peptidase T1B family.

Phylogenomic databases

eggNOGiCOG0638.
HOGENOMiHOG000182856.
HOVERGENiHBG093416.
InParanoidiP40306.
KOiK02733.
OMAiQYRFAPG.
OrthoDBiEOG7CRTQJ.
PhylomeDBiP40306.
TreeFamiTF106222.

Family and domain databases

Gene3Di3.60.20.10. 1 hit.
InterProiIPR029055. Ntn_hydrolases_N.
IPR000243. Pept_T1A_subB.
IPR024689. Proteasome_bsu_C.
IPR016050. Proteasome_bsu_CS.
IPR001353. Proteasome_sua/b.
IPR023333. Proteasome_suB-type.
[Graphical view]
PfamiPF12465. Pr_beta_C. 1 hit.
PF00227. Proteasome. 1 hit.
[Graphical view]
PRINTSiPR00141. PROTEASOME.
SUPFAMiSSF56235. SSF56235. 1 hit.
PROSITEiPS00854. PROTEASOME_BETA_1. 1 hit.
PS51476. PROTEASOME_BETA_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

P40306-1 [UniParc]FASTAAdd to Basket

« Hide

MLKPALEPRG GFSFENCQRN ASLERVLPGL KVPHARKTGT TIAGLVFQDG    50
VILGADTRAT NDSVVADKSC EKIHFIAPKI YCCGAGVAAD AEMTTRMVAS 100
KMELHALSTG REPRVATVTR ILRQTLFRYQ GHVGASLIVG GVDLTGPQLY 150
GVHPHGSYSR LPFTALGSGQ DAALAVLEDR FQPNMTLEAA QGLLVEAVTA 200
GILGDLGSGG NVDACVITKT GAKLLRTLSS PTEPVKRSGR YHFVPGTTAV 250
LTQTVKPLTL ELVEETVQAM EVE 273
Length:273
Mass (Da):28,936
Last modified:February 1, 1995 - v1
Checksum:iD6728E50513A45B9
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
X71874 Genomic DNA. Translation: CAA50709.1.
Y13640 mRNA. Translation: CAA73982.1.
BT019723 mRNA. Translation: AAV38528.1.
BT019724 mRNA. Translation: AAV38529.1.
AK312208 mRNA. Translation: BAG35141.1.
CH471092 Genomic DNA. Translation: EAW83187.1.
BC017198 mRNA. Translation: AAH17198.1.
BC052369 mRNA. Translation: AAH52369.1.
CCDSiCCDS10853.1.
PIRiI38135.
RefSeqiNP_002792.1. NM_002801.3.
UniGeneiHs.9661.

Genome annotation databases

EnsembliENST00000358514; ENSP00000351314; ENSG00000205220.
GeneIDi5699.
KEGGihsa:5699.
UCSCiuc002eux.2. human.

Polymorphism databases

DMDMi730376.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
X71874 Genomic DNA. Translation: CAA50709.1 .
Y13640 mRNA. Translation: CAA73982.1 .
BT019723 mRNA. Translation: AAV38528.1 .
BT019724 mRNA. Translation: AAV38529.1 .
AK312208 mRNA. Translation: BAG35141.1 .
CH471092 Genomic DNA. Translation: EAW83187.1 .
BC017198 mRNA. Translation: AAH17198.1 .
BC052369 mRNA. Translation: AAH52369.1 .
CCDSi CCDS10853.1.
PIRi I38135.
RefSeqi NP_002792.1. NM_002801.3.
UniGenei Hs.9661.

3D structure databases

ProteinModelPortali P40306.
SMRi P40306. Positions 40-258.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

BioGridi 111672. 17 interactions.
IntActi P40306. 7 interactions.
STRINGi 9606.ENSP00000351314.

Chemistry

ChEMBLi CHEMBL2364701.

Protein family/group databases

MEROPSi T01.014.

PTM databases

PhosphoSitei P40306.

Polymorphism databases

DMDMi 730376.

2D gel databases

OGPi P40306.
SWISS-2DPAGE P40306.

Proteomic databases

MaxQBi P40306.
PaxDbi P40306.
PeptideAtlasi P40306.
PRIDEi P40306.

Protocols and materials databases

DNASUi 5699.
Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENST00000358514 ; ENSP00000351314 ; ENSG00000205220 .
GeneIDi 5699.
KEGGi hsa:5699.
UCSCi uc002eux.2. human.

Organism-specific databases

CTDi 5699.
GeneCardsi GC16M067968.
HGNCi HGNC:9538. PSMB10.
HPAi HPA030225.
MIMi 176847. gene.
neXtProti NX_P40306.
PharmGKBi PA33883.
GenAtlasi Search...

Phylogenomic databases

eggNOGi COG0638.
HOGENOMi HOG000182856.
HOVERGENi HBG093416.
InParanoidi P40306.
KOi K02733.
OMAi QYRFAPG.
OrthoDBi EOG7CRTQJ.
PhylomeDBi P40306.
TreeFami TF106222.

Enzyme and pathway databases

Reactomei REACT_111056. Cross-presentation of soluble exogenous antigens (endosomes).
REACT_111178. ER-Phagosome pathway.
REACT_1156. Orc1 removal from chromatin.
REACT_118656. Activation of NF-kappaB in B cells.
REACT_1221. CDK-mediated phosphorylation and removal of Cdc6.
REACT_13464. Regulation of activated PAK-2p34 by proteasome mediated degradation.
REACT_13565. Regulation of ornithine decarboxylase (ODC).
REACT_150471. Separation of Sister Chromatids.
REACT_1614. Ubiquitin Mediated Degradation of Phosphorylated Cdc25A.
REACT_172638. Asymmetric localization of PCP proteins.
REACT_1949. CDT1 association with the CDC6:ORC:origin complex.
REACT_200766. degradation of AXIN.
REACT_200841. degradation of DVL.
REACT_20549. Autodegradation of the E3 ubiquitin ligase COP1.
REACT_25325. AUF1 (hnRNP D0) destabilizes mRNA.
REACT_4. Ubiquitin-dependent degradation of Cyclin D1.
REACT_6761. APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1.
REACT_6785. Autodegradation of Cdh1 by Cdh1:APC/C.
REACT_6821. SCF-beta-TrCP mediated degradation of Emi1.
REACT_6871. APC/C:Cdc20 mediated degradation of Securin.
REACT_75842. Antigen processing: Ubiquitination & Proteasome degradation.
REACT_9003. SCF(Skp2)-mediated degradation of p27/p21.
REACT_9031. Vpu mediated degradation of CD4.
REACT_9453. Vif-mediated degradation of APOBEC3G.

Miscellaneous databases

ChiTaRSi PSMB10. human.
GeneWikii PSMB10.
GenomeRNAii 5699.
NextBioi 22142.
PROi P40306.
SOURCEi Search...

Gene expression databases

Bgeei P40306.
CleanExi HS_PSMB10.
Genevestigatori P40306.

Family and domain databases

Gene3Di 3.60.20.10. 1 hit.
InterProi IPR029055. Ntn_hydrolases_N.
IPR000243. Pept_T1A_subB.
IPR024689. Proteasome_bsu_C.
IPR016050. Proteasome_bsu_CS.
IPR001353. Proteasome_sua/b.
IPR023333. Proteasome_suB-type.
[Graphical view ]
Pfami PF12465. Pr_beta_C. 1 hit.
PF00227. Proteasome. 1 hit.
[Graphical view ]
PRINTSi PR00141. PROTEASOME.
SUPFAMi SSF56235. SSF56235. 1 hit.
PROSITEi PS00854. PROTEASOME_BETA_1. 1 hit.
PS51476. PROTEASOME_BETA_2. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "A tight cluster of five unrelated human genes on chromosome 16q22.1."
    Larsen F., Solheim J., Kristensen T., Kolstoe A.-B., Prydz H.
    Hum. Mol. Genet. 2:1589-1595(1993) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
  2. "Constitutive and interferon-gamma-induced expression of the human proteasome subunit multicatalytic endopeptidase complex-like 1."
    Foss G.S., Larsen F., Solheim J., Prydz H.
    Biochim. Biophys. Acta 1402:17-28(1998) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [MRNA].
  3. "Cloning of human full-length CDSs in BD Creator(TM) system donor vector."
    Kalnine N., Chen X., Rolfs A., Halleck A., Hines L., Eisenstein S., Koundinya M., Raphael J., Moreira D., Kelley T., LaBaer J., Lin Y., Phelan M., Farmer A.
    Submitted (OCT-2004) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
  4. "Complete sequencing and characterization of 21,243 full-length human cDNAs."
    Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H., Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S.
    , Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K., Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A., Sudo H., Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M., Takahashi M., Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y., Abe K., Kamihara K., Katsuta N., Sato K., Tanikawa M., Yamazaki M., Ninomiya K., Ishibashi T., Yamashita H., Murakawa K., Fujimori K., Tanai H., Kimata M., Watanabe M., Hiraoka S., Chiba Y., Ishida S., Ono Y., Takiguchi S., Watanabe S., Yosida M., Hotuta T., Kusano J., Kanehori K., Takahashi-Fujii A., Hara H., Tanase T.-O., Nomura Y., Togiya S., Komai F., Hara R., Takeuchi K., Arita M., Imose N., Musashino K., Yuuki H., Oshima A., Sasaki N., Aotsuka S., Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S., Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O., Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H., Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B., Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y., Fujimori Y., Komiyama M., Tashiro H., Tanigami A., Fujiwara T., Ono T., Yamada K., Fujii Y., Ozaki K., Hirao M., Ohmori Y., Kawabata A., Hikiji T., Kobatake N., Inagaki H., Ikema Y., Okamoto S., Okitani R., Kawakami T., Noguchi S., Itoh T., Shigeta K., Senba T., Matsumura K., Nakajima Y., Mizuno T., Morinaga M., Sasaki M., Togashi T., Oyama M., Hata H., Watanabe M., Komatsu T., Mizushima-Sugano J., Satoh T., Shirai Y., Takahashi Y., Nakagawa K., Okumura K., Nagase T., Nomura N., Kikuchi H., Masuho Y., Yamashita R., Nakai K., Yada T., Nakamura Y., Ohara O., Isogai T., Sugano S.
    Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Tissue: Small intestine.
  5. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
  6. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Tissue: B-cell and Lymph.
  7. "Newly identified pair of proteasomal subunits regulated reciprocally by interferon gamma."
    Hisamatsu H., Shimbara N., Saito Y., Kristensen P., Hendil K.B., Fujiwara T., Takahashi E., Tanahashi N., Tamura T., Ichihara A., Tanaka K.
    J. Exp. Med. 183:1807-1816(1996) [PubMed] [Europe PMC] [Abstract]
    Cited for: INDUCTION BY IFNG.
  8. "Interferon regulatory factor 1 mediates the interferon-gamma induction of the human immunoproteasome subunit multicatalytic endopeptidase complex-like 1."
    Foss G.S., Prydz H.
    J. Biol. Chem. 274:35196-35202(1999) [PubMed] [Europe PMC] [Abstract]
    Cited for: INDUCTION BY IFNG AND IRF1.
  9. "Tumor necrosis factor-alpha induces coordinated changes in major histocompatibility class I presentation pathway, resulting in increased stability of class I complexes at the cell surface."
    Hallermalm K., Seki K., Wei C., Castelli C., Rivoltini L., Kiessling R., Levitskaya J.
    Blood 98:1108-1115(2001) [PubMed] [Europe PMC] [Abstract]
    Cited for: INDUCTION BY TNF AND IFNG.
  10. "Bipartite regulation of different components of the MHC class I antigen-processing machinery during dendritic cell maturation."
    Li J., Schuler-Thurner B., Schuler G., Huber C., Seliger B.
    Int. Immunol. 13:1515-1523(2001) [PubMed] [Europe PMC] [Abstract]
    Cited for: DEVELOPMENTAL STAGE.
  11. "Human immunodeficiency virus-1 Tat protein interacts with distinct proteasomal alpha and beta subunits."
    Apcher G.S., Heink S., Zantopf D., Kloetzel P.-M., Schmid H.-P., Mayer R.J., Krueger E.
    FEBS Lett. 553:200-204(2003) [PubMed] [Europe PMC] [Abstract]
    Cited for: INTERACTION WITH HIV-1 TAT.
  12. "Potential effects of tetrodotoxin exposure to human glial cells postulated using microarray approach."
    Raghavendra Prasad H.S., Qi Z., Srinivasan K.N., Gopalakrishnakone P.
    Toxicon 44:597-608(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: INDUCTION BY TETRODOTOXIN.
  13. "IRF-1 mediates upregulation of LMP7 by IFN-gamma and concerted expression of immunosubunits of the proteasome."
    Namiki S., Nakamura T., Oshima S., Yamazaki M., Sekine Y., Tsuchiya K., Okamoto R., Kanai T., Watanabe M.
    FEBS Lett. 579:2781-2787(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: INDUCTION BY IFNG AND IRF1.
  14. "Genome-wide gene expression differences in Crohn's disease and ulcerative colitis from endoscopic pinch biopsies: insights into distinctive pathogenesis."
    Wu F., Dassopoulos T., Cope L., Maitra A., Brant S.R., Harris M.L., Bayless T.M., Parmigiani G., Chakravarti S.
    Inflamm. Bowel Dis. 13:807-821(2007) [PubMed] [Europe PMC] [Abstract]
    Cited for: INDUCTION.
  15. "CD40 induces antigen transporter and immunoproteasome gene expression in carcinomas via the coordinated action of NF-kappaB and of NF-kappaB-mediated de novo synthesis of IRF-1."
    Moschonas A., Kouraki M., Knox P.G., Thymiakou E., Kardassis D., Eliopoulos A.G.
    Mol. Cell. Biol. 28:6208-6222(2008) [PubMed] [Europe PMC] [Abstract]
    Cited for: INDUCTION BY CD40L.
  16. Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
  17. Cited for: ACETYLATION [LARGE SCALE ANALYSIS] AT MET-1, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].

Entry informationi

Entry nameiPSB10_HUMAN
AccessioniPrimary (citable) accession number: P40306
Secondary accession number(s): B2R5J4, Q5U098
Entry historyi
Integrated into UniProtKB/Swiss-Prot: February 1, 1995
Last sequence update: February 1, 1995
Last modified: September 3, 2014
This is version 148 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 16
    Human chromosome 16: entries, gene names and cross-references to MIM
  2. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
  3. Peptidase families
    Classification of peptidase families and list of entries
  4. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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