##gff-version 3
P40305	UniProtKB	Transit peptide	1	33	.	.	.	Note=Mitochondrion;Ontology_term=ECO:0000305;evidence=ECO:0000305|PubMed:18330707;Dbxref=PMID:18330707	
P40305	UniProtKB	Chain	34	122	.	.	.	ID=PRO_0000147372;Note=Interferon alpha-inducible protein 27%2C mitochondrial	
P40305	UniProtKB	Transmembrane	34	57	.	.	.	Note=Helical;Ontology_term=ECO:0000255;evidence=ECO:0000255	
P40305	UniProtKB	Transmembrane	71	91	.	.	.	Note=Helical;Ontology_term=ECO:0000255;evidence=ECO:0000255	
P40305	UniProtKB	Transmembrane	99	119	.	.	.	Note=Helical;Ontology_term=ECO:0000255;evidence=ECO:0000255	
P40305	UniProtKB	Region	76	122	.	.	.	Note=Mediates interaction with SKP2 and hepatitis C virus non-structural protein NS5A;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:27194766;Dbxref=PMID:27194766	
P40305	UniProtKB	Region	103	112	.	.	.	Note=Required for hepatitis C virus non-structural protein NS5A degradation;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:27194766;Dbxref=PMID:27194766	
P40305	UniProtKB	Cross-link	69	69	.	.	.	Note=Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin);Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:36426955;Dbxref=PMID:36426955	
P40305	UniProtKB	Alternative sequence	1	48	.	.	.	ID=VSP_059907;Note=In isoform 4. Missing	
P40305	UniProtKB	Alternative sequence	1	43	.	.	.	ID=VSP_059908;Note=In isoform 3. Missing	
P40305	UniProtKB	Alternative sequence	43	45	.	.	.	ID=VSP_059909;Note=In isoform 2. Missing	
P40305	UniProtKB	Natural variant	109	109	.	.	.	ID=VAR_028066;Note=S->F;Dbxref=dbSNP:rs2227974	
P40305	UniProtKB	Mutagenesis	56	56	.	.	.	Note=Increased pro-apoptotic activity%3B when associated with D-96. F->D;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:27673746;Dbxref=PMID:27673746	
P40305	UniProtKB	Mutagenesis	69	69	.	.	.	Note=Complete loss of TRIM21-mediated ubiquitination. K->R;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:36426955;Dbxref=PMID:36426955	
P40305	UniProtKB	Mutagenesis	96	96	.	.	.	Note=Increased pro-apoptotic activity%3B when associated with D-56. A->D;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:27673746;Dbxref=PMID:27673746	
P40305	UniProtKB	Sequence conflict	89	89	.	.	.	Note=A->G;Ontology_term=ECO:0000305;evidence=ECO:0000305