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P40289

- Y669_CUPNH

UniProt

P40289 - Y669_CUPNH

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Protein

Putative tyrosine-protein phosphatase H16_A0669

Gene

H16_A0669

Organism
Cupriavidus necator (strain ATCC 17699 / H16 / DSM 428 / Stanier 337) (Ralstonia eutropha)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Catalytic activityi

Protein tyrosine phosphate + H2O = protein tyrosine + phosphate.PROSITE-ProRule annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei169 – 1691Phosphocysteine intermediatePROSITE-ProRule annotation

GO - Molecular functioni

  1. protein tyrosine phosphatase activity Source: UniProtKB-EC
Complete GO annotation...

Keywords - Molecular functioni

Hydrolase, Protein phosphatase

Enzyme and pathway databases

BioCyciCNEC381666:GJUJ-668-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Putative tyrosine-protein phosphatase H16_A0669 (EC:3.1.3.48)
Gene namesi
Ordered Locus Names:H16_A0669
OrganismiCupriavidus necator (strain ATCC 17699 / H16 / DSM 428 / Stanier 337) (Ralstonia eutropha)
Taxonomic identifieri381666 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaBetaproteobacteriaBurkholderialesBurkholderiaceaeCupriavidus
ProteomesiUP000008210: Chromosome 1

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 1515Sequence AnalysisAdd
BLAST
Chaini16 – 273258Putative tyrosine-protein phosphatase H16_A0669PRO_0000066290Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi381666.H16_A0669.

Structurei

3D structure databases

ProteinModelPortaliP40289.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Keywords - Domaini

Signal

Phylogenomic databases

eggNOGiCOG2365.
HOGENOMiHOG000036053.
KOiK01104.
OMAiANTAGPQ.
OrthoDBiEOG6ZPSXQ.

Family and domain databases

Gene3Di3.90.190.10. 1 hit.
InterProiIPR029021. Prot-tyrosine_phosphatase-like.
IPR000387. Tyr/Dual-sp_Pase.
IPR026893. Tyr/Ser_Pase_IphP-type.
IPR016130. Tyr_Pase_AS.
IPR025163. Tyr_Phosphatase_C_dom.
[Graphical view]
PfamiPF13350. Y_phosphatase3. 1 hit.
PF13348. Y_phosphatase3C. 1 hit.
[Graphical view]
SUPFAMiSSF52799. SSF52799. 1 hit.
PROSITEiPS00383. TYR_PHOSPHATASE_1. 1 hit.
PS50056. TYR_PHOSPHATASE_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

P40289 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MIKWLQRAGC LSAHAVVPQA PAAASVQGRH DLAFDTISNA RDLGGLAGAG
60 70 80 90 100
GRRVRQGRLY RSGNPALASA ADLERLQTLG LDMVVDFRSP GEKSPEEAAF
110 120 130 140 150
GQRFHWVAAP VLEGSMAMDV LMPRLRASTP AQMDAFMLEV YGDFPVRYRE
160 170 180 190 200
AFAGFMRTAQ GGKTLLFHCT AGKDRTGFAA LLLLAALGVA QDDILANYLE
210 220 230 240 250
SNQRNAQFNQ TALARMAGLG VAPAVMTPLL EVRASYLDAS MRAIDAGWGS
260 270
VDNYLRDALE VDVAQLRGHY LAG
Length:273
Mass (Da):29,325
Last modified:January 23, 2007 - v2
Checksum:i111724C25FF66286
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AM260479 Genomic DNA. Translation: CAJ91817.1.
Z22737 Genomic DNA. No translation available.
RefSeqiYP_725185.1. NC_008313.1.

Genome annotation databases

EnsemblBacteriaiCAJ91817; CAJ91817; H16_A0669.
GeneIDi4247616.
KEGGireh:H16_A0669.
PATRICi35230739. VBIRalEut6770_1038.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AM260479 Genomic DNA. Translation: CAJ91817.1 .
Z22737 Genomic DNA. No translation available.
RefSeqi YP_725185.1. NC_008313.1.

3D structure databases

ProteinModelPortali P40289.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 381666.H16_A0669.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai CAJ91817 ; CAJ91817 ; H16_A0669 .
GeneIDi 4247616.
KEGGi reh:H16_A0669.
PATRICi 35230739. VBIRalEut6770_1038.

Phylogenomic databases

eggNOGi COG2365.
HOGENOMi HOG000036053.
KOi K01104.
OMAi ANTAGPQ.
OrthoDBi EOG6ZPSXQ.

Enzyme and pathway databases

BioCyci CNEC381666:GJUJ-668-MONOMER.

Family and domain databases

Gene3Di 3.90.190.10. 1 hit.
InterProi IPR029021. Prot-tyrosine_phosphatase-like.
IPR000387. Tyr/Dual-sp_Pase.
IPR026893. Tyr/Ser_Pase_IphP-type.
IPR016130. Tyr_Pase_AS.
IPR025163. Tyr_Phosphatase_C_dom.
[Graphical view ]
Pfami PF13350. Y_phosphatase3. 1 hit.
PF13348. Y_phosphatase3C. 1 hit.
[Graphical view ]
SUPFAMi SSF52799. SSF52799. 1 hit.
PROSITEi PS00383. TYR_PHOSPHATASE_1. 1 hit.
PS50056. TYR_PHOSPHATASE_2. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 17699 / H16 / DSM 428 / Stanier 337.
  2. "The Alcaligenes eutrophus ldh structural gene encodes a novel type of lactate dehydrogenase."
    Jendrossek D., Kratzin H.D., Steinbuechel A.
    FEMS Microbiol. Lett. 112:229-235(1993) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1-77.

Entry informationi

Entry nameiY669_CUPNH
AccessioniPrimary (citable) accession number: P40289
Secondary accession number(s): Q0KDV4
Entry historyi
Integrated into UniProtKB/Swiss-Prot: February 1, 1995
Last sequence update: January 23, 2007
Last modified: October 1, 2014
This is version 75 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3