Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Putative tyrosine-protein phosphatase H16_A0669

Gene

H16_A0669

Organism
Cupriavidus necator (strain ATCC 17699 / H16 / DSM 428 / Stanier 337) (Ralstonia eutropha)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

Protein tyrosine phosphate + H2O = protein tyrosine + phosphate.PROSITE-ProRule annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei169 – 1691Phosphocysteine intermediatePROSITE-ProRule annotation

GO - Molecular functioni

  1. protein tyrosine phosphatase activity Source: UniProtKB-EC
Complete GO annotation...

Keywords - Molecular functioni

Hydrolase, Protein phosphatase

Enzyme and pathway databases

BioCyciCNEC381666:GJUJ-668-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Putative tyrosine-protein phosphatase H16_A0669 (EC:3.1.3.48)
Gene namesi
Ordered Locus Names:H16_A0669
OrganismiCupriavidus necator (strain ATCC 17699 / H16 / DSM 428 / Stanier 337) (Ralstonia eutropha)
Taxonomic identifieri381666 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaBetaproteobacteriaBurkholderialesBurkholderiaceaeCupriavidus
ProteomesiUP000008210 Componenti: Chromosome 1

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 1515Sequence AnalysisAdd
BLAST
Chaini16 – 273258Putative tyrosine-protein phosphatase H16_A0669PRO_0000066290Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi381666.H16_A0669.

Family & Domainsi

Sequence similaritiesi

Keywords - Domaini

Signal

Phylogenomic databases

eggNOGiCOG2365.
HOGENOMiHOG000036053.
KOiK01104.
OMAiLMQDTYR.
OrthoDBiEOG6ZPSXQ.

Family and domain databases

Gene3Di3.90.190.10. 1 hit.
InterProiIPR029021. Prot-tyrosine_phosphatase-like.
IPR000387. Tyr/Dual-sp_Pase.
IPR026893. Tyr/Ser_Pase_IphP-type.
IPR016130. Tyr_Pase_AS.
IPR025163. Tyr_Phosphatase_C_dom.
[Graphical view]
PfamiPF13350. Y_phosphatase3. 1 hit.
PF13348. Y_phosphatase3C. 1 hit.
[Graphical view]
SUPFAMiSSF52799. SSF52799. 1 hit.
PROSITEiPS00383. TYR_PHOSPHATASE_1. 1 hit.
PS50056. TYR_PHOSPHATASE_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

P40289-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MIKWLQRAGC LSAHAVVPQA PAAASVQGRH DLAFDTISNA RDLGGLAGAG
60 70 80 90 100
GRRVRQGRLY RSGNPALASA ADLERLQTLG LDMVVDFRSP GEKSPEEAAF
110 120 130 140 150
GQRFHWVAAP VLEGSMAMDV LMPRLRASTP AQMDAFMLEV YGDFPVRYRE
160 170 180 190 200
AFAGFMRTAQ GGKTLLFHCT AGKDRTGFAA LLLLAALGVA QDDILANYLE
210 220 230 240 250
SNQRNAQFNQ TALARMAGLG VAPAVMTPLL EVRASYLDAS MRAIDAGWGS
260 270
VDNYLRDALE VDVAQLRGHY LAG
Length:273
Mass (Da):29,325
Last modified:January 23, 2007 - v2
Checksum:i111724C25FF66286
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AM260479 Genomic DNA. Translation: CAJ91817.1.
Z22737 Genomic DNA. No translation available.
RefSeqiYP_725185.1. NC_008313.1.

Genome annotation databases

EnsemblBacteriaiCAJ91817; CAJ91817; H16_A0669.
KEGGireh:H16_A0669.
PATRICi35230739. VBIRalEut6770_1038.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AM260479 Genomic DNA. Translation: CAJ91817.1.
Z22737 Genomic DNA. No translation available.
RefSeqiYP_725185.1. NC_008313.1.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi381666.H16_A0669.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiCAJ91817; CAJ91817; H16_A0669.
KEGGireh:H16_A0669.
PATRICi35230739. VBIRalEut6770_1038.

Phylogenomic databases

eggNOGiCOG2365.
HOGENOMiHOG000036053.
KOiK01104.
OMAiLMQDTYR.
OrthoDBiEOG6ZPSXQ.

Enzyme and pathway databases

BioCyciCNEC381666:GJUJ-668-MONOMER.

Family and domain databases

Gene3Di3.90.190.10. 1 hit.
InterProiIPR029021. Prot-tyrosine_phosphatase-like.
IPR000387. Tyr/Dual-sp_Pase.
IPR026893. Tyr/Ser_Pase_IphP-type.
IPR016130. Tyr_Pase_AS.
IPR025163. Tyr_Phosphatase_C_dom.
[Graphical view]
PfamiPF13350. Y_phosphatase3. 1 hit.
PF13348. Y_phosphatase3C. 1 hit.
[Graphical view]
SUPFAMiSSF52799. SSF52799. 1 hit.
PROSITEiPS00383. TYR_PHOSPHATASE_1. 1 hit.
PS50056. TYR_PHOSPHATASE_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 17699 / H16 / DSM 428 / Stanier 337.
  2. "The Alcaligenes eutrophus ldh structural gene encodes a novel type of lactate dehydrogenase."
    Jendrossek D., Kratzin H.D., Steinbuechel A.
    FEMS Microbiol. Lett. 112:229-235(1993) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1-77.

Entry informationi

Entry nameiY669_CUPNH
AccessioniPrimary (citable) accession number: P40289
Secondary accession number(s): Q0KDV4
Entry historyi
Integrated into UniProtKB/Swiss-Prot: February 1, 1995
Last sequence update: January 23, 2007
Last modified: April 1, 2015
This is version 77 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.