P40212 (RL13B_YEAST) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
60S ribosomal protein L13-B

Gene names

Name:	RPL13B
Synonyms:	RPL13
Ordered Locus Names:	YMR142C
ORF Names:	YM9375.11C

Organism

Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) [Reference proteome]

Taxonomic identifier

559292 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Fungi › Dikarya › Ascomycota › saccharomyceta › Saccharomycotina › Saccharomycetes › Saccharomycetales › Saccharomycetaceae › Saccharomyces › Saccharomyces cerevisiae

Protein attributes

Sequence length	199 AA.
Sequence status	Complete.
Protein existence	Evidence at protein level

General annotation (Comments)

Subunit structure	Component of the large ribosomal subunit. Mature ribosomes consist of a small (40S) and a large (60S) subunit. The 40S subunit contains 32 different proteins (encoded by 56 genes) and 1 molecule of RNA (18S). The 60S subunit contains 46 different proteins (encoded by 81 genes) and 3 molecules of RNA (25S, 5.8S and 5S). Ref.3
Subcellular location	Cytoplasm Ref.4.
Miscellaneous	Present with 54200 molecules/cell in log phase SD medium. There are 2 genes for L13 in yeast.
Sequence similarities	Belongs to the ribosomal protein L13e family.

Ontologies

Keywords
Cellular component	Cytoplasm
Molecular function	Ribonucleoprotein Ribosomal protein
PTM	Phosphoprotein
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	cytoplasmic translation Traceable author statement Ref.3. Source: SGD
Cellular_component	cytosolic large ribosomal subunit Traceable author statement Ref.3. Source: SGD
Molecular_function	structural constituent of ribosome Traceable author statement Ref.3. Source: SGD
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 199	199	60S ribosomal protein L13-B		PRO_0000192939
Amino acid modifications
	Modified residue	62	1	Phosphothreonine Ref.7
	Modified residue	140	1	Phosphoserine Ref.6

Sequences

	Sequence		Length	Mass (Da)
	P40212 [UniParc]. Last modified February 1, 1995. Version 1. Checksum: BEA3B423EE76EF23	FASTA	199	22,525
	10 20 30 40 50 60 MAISKNLPIL KNHFRKHWQE RVKVHFDQAG KKVSRRNARA ARAAKIAPRP LDLLRPVVRA 70 80 90 100 110 120 PTVKYNRKVR AGRGFTLAEV KAAGLTAAYA RTIGIAVDHR RQNRNQEIFD ANVQRLKEYQ 130 140 150 160 170 180 SKIIVFPRDG KAPEAEQVLS AAATFPIAQP ATDVEARAVQ DNGESAFRTL RLARSEKKFR 190 GIREKRAREK AEAEAEKKK

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"The nucleotide sequence of Saccharomyces cerevisiae chromosome XIII." Bowman S., Churcher C.M., Badcock K., Brown D., Chillingworth T., Connor R., Dedman K., Devlin K., Gentles S., Hamlin N., Hunt S., Jagels K., Lye G., Moule S., Odell C., Pearson D., Rajandream M.A., Rice P. , Skelton J., Walsh S.V., Whitehead S., Barrell B.G. Nature 387:90-93(1997) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 204511 / S288c / AB972.
[2]	Saccharomyces Genome Database Submitted (DEC-2009) to the EMBL/GenBank/DDBJ databases Cited for: GENOME REANNOTATION. Strain: ATCC 204508 / S288c.
[3]	"The list of cytoplasmic ribosomal proteins of Saccharomyces cerevisiae." Planta R.J., Mager W.H. Yeast 14:471-477(1998) [PubMed] [Europe PMC] [Abstract] Cited for: NOMENCLATURE, SUBUNIT.
[4]	"Global analysis of protein localization in budding yeast." Huh W.-K., Falvo J.V., Gerke L.C., Carroll A.S., Howson R.W., Weissman J.S., O'Shea E.K. Nature 425:686-691(2003) [PubMed] [Europe PMC] [Abstract] Cited for: SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS].
[5]	"Global analysis of protein expression in yeast." Ghaemmaghami S., Huh W.-K., Bower K., Howson R.W., Belle A., Dephoure N., O'Shea E.K., Weissman J.S. Nature 425:737-741(2003) [PubMed] [Europe PMC] [Abstract] Cited for: LEVEL OF PROTEIN EXPRESSION [LARGE SCALE ANALYSIS].
[6]	"Quantitative phosphoproteomics applied to the yeast pheromone signaling pathway." Gruhler A., Olsen J.V., Mohammed S., Mortensen P., Faergeman N.J., Mann M., Jensen O.N. Mol. Cell. Proteomics 4:310-327(2005) [PubMed] [Europe PMC] [Abstract] Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-140, MASS SPECTROMETRY. Strain: YAL6B.
[7]	"Analysis of phosphorylation sites on proteins from Saccharomyces cerevisiae by electron transfer dissociation (ETD) mass spectrometry." Chi A., Huttenhower C., Geer L.Y., Coon J.J., Syka J.E.P., Bai D.L., Shabanowitz J., Burke D.J., Troyanskaya O.G., Hunt D.F. Proc. Natl. Acad. Sci. U.S.A. 104:2193-2198(2007) [PubMed] [Europe PMC] [Abstract] Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT THR-62, MASS SPECTROMETRY.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	Z47071 Genomic DNA. Translation: CAA87356.1. BK006946 Genomic DNA. Translation: DAA10038.1.
PIR	S50398.
RefSeq	NP_013862.1. NM_001182644.1.
3D structure databases
ProteinModelPortal	P40212.
SMR	P40212. Positions 2-195.
ModBase	Search...
Protein-protein interaction databases
DIP	DIP-2591N.
IntAct	P40212. 57 interactions.
MINT	MINT-8285395.
STRING	4932.YMR142C.
Proteomic databases
PeptideAtlas	P40212.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblFungi	YMR142C; YMR142C; YMR142C.
GeneID	855173.
KEGG	sce:YMR142C.
Organism-specific databases
CYGD	YMR142c.
SGD	S000004750. RPL13B.
Phylogenomic databases
GeneTree	ENSGT00390000007818.
HOGENOM	HOG000170452.
KO	K02873.
OMA	LNPHFHK.
OrthoDB	EOG415KPR.
Enzyme and pathway databases
BioCyc	YEAST:G3O-32834-MONOMER.
Gene expression databases
Genevestigator	P40212.
GermOnline	YMR142C. Saccharomyces cerevisiae.
Family and domain databases
InterPro	IPR001380. Ribosomal_L13e. IPR018256. Ribosomal_L13e_CS. [Graphical view]
PANTHER	PTHR11722. PTHR11722. 1 hit.
Pfam	PF01294. Ribosomal_L13e. 1 hit. [Graphical view]
PROSITE	PS01104. RIBOSOMAL_L13E. 1 hit. [Graphical view]
ProtoNet	Search...
Other
NextBio	978614.

Entry information

Entry name

RL13B_YEAST

Accession

Primary (citable) accession number: P40212
Secondary accession number(s): D6VZW4

Entry history

Integrated into UniProtKB/Swiss-Prot:	February 1, 1995
Last sequence update:	February 1, 1995
Last modified:	May 29, 2013
This is version 95 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Fungal Protein Annotation Program