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Protein

Protein MMF1, mitochondrial

Gene

MMF1

Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Plays a role in the maintenance of mitochondrial DNA.

Miscellaneous

Present with 168000 molecules/cell in log phase SD medium.1 Publication

GO - Biological processi

  • isoleucine biosynthetic process Source: SGD
  • mitochondrial translation Source: SGD

Enzyme and pathway databases

BioCyciYEAST:G3O-31322-MONOMER
ReactomeiR-SCE-8849175 Threonine catabolism

Names & Taxonomyi

Protein namesi
Recommended name:
Protein MMF1, mitochondrial
Alternative name(s):
Isoleucine biosynthesis and maintenance of intact mitochondria 1
Maintenance of mitochondrial function 1
Gene namesi
Name:MMF1
Synonyms:IBM1
Ordered Locus Names:YIL051C
OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Taxonomic identifieri559292 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
Proteomesi
  • UP000002311 Componenti: Chromosome IX

Organism-specific databases

EuPathDBiFungiDB:YIL051C
SGDiS000001313 MMF1

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Mitochondrion

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transit peptidei1 – 17Mitochondrion2 PublicationsAdd BLAST17
ChainiPRO_000003620918 – 145Protein MMF1, mitochondrialAdd BLAST128

Proteomic databases

MaxQBiP40185
PaxDbiP40185
PRIDEiP40185
TopDownProteomicsiP40185

2D gel databases

SWISS-2DPAGEiP40185

PTM databases

iPTMnetiP40185

Interactioni

Protein-protein interaction databases

BioGridi34939, 92 interactors
DIPiDIP-4714N
IntActiP40185, 6 interactors
MINTiP40185
STRINGi4932.YIL051C

Structurei

Secondary structure

1145
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details
Feature keyPosition(s)DescriptionActionsGraphical viewLength
Beta strandi21 – 24Combined sources4
Beta strandi38 – 42Combined sources5
Beta strandi45 – 51Combined sources7
Helixi65 – 82Combined sources18
Helixi87 – 89Combined sources3
Beta strandi90 – 98Combined sources9
Helixi100 – 102Combined sources3
Helixi103 – 113Combined sources11
Beta strandi114 – 116Combined sources3
Beta strandi120 – 125Combined sources6
Helixi130 – 132Combined sources3
Beta strandi134 – 142Combined sources9

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
3QUWX-ray1.75A1-145[»]
ProteinModelPortaliP40185
SMRiP40185
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the RutC family.Curated

Keywords - Domaini

Transit peptide

Phylogenomic databases

GeneTreeiENSGT00420000029792
HOGENOMiHOG000267215
InParanoidiP40185
OMAiAQTHKTI
OrthoDBiEOG092C3IOJ

Family and domain databases

Gene3Di3.30.1330.40, 1 hit
InterProiView protein in InterPro
IPR006056 RidA
IPR019897 RidA_CS
IPR035959 RutC-like_sf
IPR006175 YjgF/YER057c/UK114
PANTHERiPTHR11803 PTHR11803, 1 hit
PfamiView protein in Pfam
PF01042 Ribonuc_L-PSP, 1 hit
SUPFAMiSSF55298 SSF55298, 1 hit
TIGRFAMsiTIGR00004 TIGR00004, 1 hit
PROSITEiView protein in PROSITE
PS01094 UPF0076, 1 hit

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

P40185-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MFLRNSVLRT APVLRRGITT LTPVSTKLAP PAAASYSQAM KANNFVYVSG
60 70 80 90 100
QIPYTPDNKP VQGSISEKAE QVFQNVKNIL AESNSSLDNI VKVNVFLADM
110 120 130 140
KNFAEFNSVY AKHFHTHKPA RSCVGVASLP LNVDLEMEVI AVEKN
Length:145
Mass (Da):15,908
Last modified:February 1, 1995 - v1
Checksum:iF2DC4E32C04CED45
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB050474 Genomic DNA Translation: BAB20814.1
Z38060 Genomic DNA Translation: CAA86171.1
AY558301 Genomic DNA Translation: AAS56627.1
BK006942 Genomic DNA Translation: DAA08496.1
PIRiS48428
RefSeqiNP_012213.3, NM_001179401.3

Genome annotation databases

EnsemblFungiiYIL051C; YIL051C; YIL051C
GeneIDi854760
KEGGisce:YIL051C

Similar proteinsi

Entry informationi

Entry nameiMMF1_YEAST
AccessioniPrimary (citable) accession number: P40185
Secondary accession number(s): D6VVN0
Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 1, 1995
Last sequence update: February 1, 1995
Last modified: June 20, 2018
This is version 167 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Direct protein sequencing, Reference proteome

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