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Protein

Protein MMF1, mitochondrial

Gene

MMF1

Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed-Annotation score: Annotation score: 4 out of 5-Experimental evidence at protein leveli

Functioni

Plays a role in the maintenance of mitochondrial DNA.

GO - Biological processi

  • isoleucine biosynthetic process Source: SGD
  • mitochondrial translation Source: SGD
Complete GO annotation...

Enzyme and pathway databases

BioCyciYEAST:G3O-31322-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Protein MMF1, mitochondrial
Alternative name(s):
Isoleucine biosynthesis and maintenance of intact mitochondria 1
Maintenance of mitochondrial function 1
Gene namesi
Name:MMF1
Synonyms:IBM1
Ordered Locus Names:YIL051C
OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Taxonomic identifieri559292 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
Proteomesi
  • UP000002311 Componenti: Chromosome IX

Organism-specific databases

EuPathDBiFungiDB:YIL051C.
SGDiS000001313. MMF1.

Subcellular locationi

GO - Cellular componenti

  • mitochondrial matrix Source: SGD
Complete GO annotation...

Keywords - Cellular componenti

Mitochondrion

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transit peptidei1 – 17Mitochondrion2 PublicationsAdd BLAST17
ChainiPRO_000003620918 – 145Protein MMF1, mitochondrialAdd BLAST128

Proteomic databases

MaxQBiP40185.
PRIDEiP40185.
TopDownProteomicsiP40185.

2D gel databases

SWISS-2DPAGEP40185.

PTM databases

iPTMnetiP40185.

Interactioni

Protein-protein interaction databases

BioGridi34939. 85 interactors.
DIPiDIP-4714N.
IntActiP40185. 6 interactors.
MINTiMINT-487056.

Structurei

Secondary structure

1145
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details
Feature keyPosition(s)DescriptionActionsGraphical viewLength
Beta strandi21 – 24Combined sources4
Beta strandi38 – 42Combined sources5
Beta strandi45 – 51Combined sources7
Helixi65 – 82Combined sources18
Helixi87 – 89Combined sources3
Beta strandi90 – 98Combined sources9
Helixi100 – 102Combined sources3
Helixi103 – 113Combined sources11
Beta strandi114 – 116Combined sources3
Beta strandi120 – 125Combined sources6
Helixi130 – 132Combined sources3
Beta strandi134 – 142Combined sources9

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
3QUWX-ray1.75A1-145[»]
ProteinModelPortaliP40185.
SMRiP40185.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the RutC family.Curated

Keywords - Domaini

Transit peptide

Phylogenomic databases

GeneTreeiENSGT00420000029792.
HOGENOMiHOG000267215.
InParanoidiP40185.
OMAiEEYAKWF.
OrthoDBiEOG092C3IOJ.

Family and domain databases

Gene3Di3.30.1330.40. 1 hit.
InterProiIPR013813. Endoribo_LPSP/chorism_mut-like.
IPR006056. RidA.
IPR019897. RidA_CS.
IPR006175. YjgF/YER057c/UK114.
[Graphical view]
PANTHERiPTHR11803. PTHR11803. 1 hit.
PfamiPF01042. Ribonuc_L-PSP. 1 hit.
[Graphical view]
SUPFAMiSSF55298. SSF55298. 1 hit.
TIGRFAMsiTIGR00004. TIGR00004. 1 hit.
PROSITEiPS01094. UPF0076. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

P40185-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MFLRNSVLRT APVLRRGITT LTPVSTKLAP PAAASYSQAM KANNFVYVSG
60 70 80 90 100
QIPYTPDNKP VQGSISEKAE QVFQNVKNIL AESNSSLDNI VKVNVFLADM
110 120 130 140
KNFAEFNSVY AKHFHTHKPA RSCVGVASLP LNVDLEMEVI AVEKN
Length:145
Mass (Da):15,908
Last modified:February 1, 1995 - v1
Checksum:iF2DC4E32C04CED45
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB050474 Genomic DNA. Translation: BAB20814.1.
Z38060 Genomic DNA. Translation: CAA86171.1.
AY558301 Genomic DNA. Translation: AAS56627.1.
BK006942 Genomic DNA. Translation: DAA08496.1.
PIRiS48428.
RefSeqiNP_012213.3. NM_001179401.3.

Genome annotation databases

EnsemblFungiiYIL051C; YIL051C; YIL051C.
GeneIDi854760.
KEGGisce:YIL051C.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB050474 Genomic DNA. Translation: BAB20814.1.
Z38060 Genomic DNA. Translation: CAA86171.1.
AY558301 Genomic DNA. Translation: AAS56627.1.
BK006942 Genomic DNA. Translation: DAA08496.1.
PIRiS48428.
RefSeqiNP_012213.3. NM_001179401.3.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
3QUWX-ray1.75A1-145[»]
ProteinModelPortaliP40185.
SMRiP40185.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi34939. 85 interactors.
DIPiDIP-4714N.
IntActiP40185. 6 interactors.
MINTiMINT-487056.

PTM databases

iPTMnetiP40185.

2D gel databases

SWISS-2DPAGEP40185.

Proteomic databases

MaxQBiP40185.
PRIDEiP40185.
TopDownProteomicsiP40185.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblFungiiYIL051C; YIL051C; YIL051C.
GeneIDi854760.
KEGGisce:YIL051C.

Organism-specific databases

EuPathDBiFungiDB:YIL051C.
SGDiS000001313. MMF1.

Phylogenomic databases

GeneTreeiENSGT00420000029792.
HOGENOMiHOG000267215.
InParanoidiP40185.
OMAiEEYAKWF.
OrthoDBiEOG092C3IOJ.

Enzyme and pathway databases

BioCyciYEAST:G3O-31322-MONOMER.

Miscellaneous databases

PROiP40185.

Family and domain databases

Gene3Di3.30.1330.40. 1 hit.
InterProiIPR013813. Endoribo_LPSP/chorism_mut-like.
IPR006056. RidA.
IPR019897. RidA_CS.
IPR006175. YjgF/YER057c/UK114.
[Graphical view]
PANTHERiPTHR11803. PTHR11803. 1 hit.
PfamiPF01042. Ribonuc_L-PSP. 1 hit.
[Graphical view]
SUPFAMiSSF55298. SSF55298. 1 hit.
TIGRFAMsiTIGR00004. TIGR00004. 1 hit.
PROSITEiPS01094. UPF0076. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiMMF1_YEAST
AccessioniPrimary (citable) accession number: P40185
Secondary accession number(s): D6VVN0
Entry historyi
Integrated into UniProtKB/Swiss-Prot: February 1, 1995
Last sequence update: February 1, 1995
Last modified: November 2, 2016
This is version 155 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Miscellaneous

Present with 168000 molecules/cell in log phase SD medium.1 Publication

Keywords - Technical termi

3D-structure, Complete proteome, Direct protein sequencing, Reference proteome

Documents

  1. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  2. SIMILARITY comments
    Index of protein domains and families
  3. Yeast
    Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD
  4. Yeast chromosome IX
    Yeast (Saccharomyces cerevisiae) chromosome IX: entries and gene names

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.