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Protein

Glucans biosynthesis protein D

Gene

mdoD

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Probably involved in the control of the structural glucose backbone of osmoregulated periplasmic glucans (OPGs).

Pathwayi: osmoregulated periplasmic glucan (OPG) biosynthesis

This protein is involved in the pathway osmoregulated periplasmic glucan (OPG) biosynthesis, which is part of Glycan metabolism.
View all proteins of this organism that are known to be involved in the pathway osmoregulated periplasmic glucan (OPG) biosynthesis and in Glycan metabolism.

GO - Molecular functioni

GO - Biological processi

Enzyme and pathway databases

BioCyciEcoCyc:EG12859-MONOMER
UniPathwayiUPA00637

Names & Taxonomyi

Protein namesi
Recommended name:
Glucans biosynthesis protein D
Gene namesi
Name:mdoD
Synonyms:opgD, ydcG, yzzZ
Ordered Locus Names:b1424, JW1420
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000318 Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG12859 mdoD

Subcellular locationi

GO - Cellular componenti

  • outer membrane-bounded periplasmic space Source: EcoCyc

Keywords - Cellular componenti

Periplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 32Tat-type signal1 PublicationAdd BLAST32
ChainiPRO_000002020633 – 551Glucans biosynthesis protein DAdd BLAST519

Post-translational modificationi

Exported by the Tat system. The position of the signal peptide cleavage has been experimentally proven. Can also be exported by the Sec system.

Proteomic databases

EPDiP40120
PaxDbiP40120
PRIDEiP40120

Expressioni

Developmental stagei

Expressed essentially during the stationary growth phase when OPG synthesis has stopped.

Interactioni

Protein-protein interaction databases

BioGridi4261154, 12 interactors
IntActiP40120, 6 interactors
STRINGi316385.ECDH10B_1552

Structurei

3D structure databases

ProteinModelPortaliP40120
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the OpgD/OpgG family.Curated

Keywords - Domaini

Signal

Phylogenomic databases

eggNOGiENOG4105DJ9 Bacteria
COG3131 LUCA
HOGENOMiHOG000288262
InParanoidiP40120
OMAiDVQFFHV
PhylomeDBiP40120

Family and domain databases

Gene3Di2.60.40.10, 1 hit
2.70.98.10, 1 hit
HAMAPiMF_01068 MdoD_OpgD, 1 hit
InterProiView protein in InterPro
IPR011013 Gal_mutarotase_sf_dom
IPR014718 GH-type_carb-bd
IPR023724 Glucan_biosyn_MdoD
IPR014438 Glucan_biosyn_MdoG/MdoD
IPR007444 Glucan_biosyn_MdoG_C
IPR013783 Ig-like_fold
IPR014756 Ig_E-set
IPR006311 TAT_signal
IPR019546 TAT_signal_bac_arc
PANTHERiPTHR30504 PTHR30504, 1 hit
PfamiView protein in Pfam
PF04349 MdoG, 1 hit
PIRSFiPIRSF006281 MdoG, 1 hit
SUPFAMiSSF74650 SSF74650, 1 hit
SSF81296 SSF81296, 1 hit
TIGRFAMsiTIGR01409 TAT_signal_seq, 1 hit
PROSITEiView protein in PROSITE
PS51318 TAT, 1 hit

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

P40120-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MDRRRFIKGS MAMAAVCGTS GIASLFSQAA FAADSDIADG QTQRFDFSIL
60 70 80 90 100
QSMAHDLAQT AWRGAPRPLP DTLATMTPQA YNSIQYDAEK SLWHNVENRQ
110 120 130 140 150
LDAQFFHMGM GFRRRVRMFS VDPATHLARE IHFRPELFKY NDAGVDTKQL
160 170 180 190 200
EGQSDLGFAG FRVFKAPELA RRDVVSFLGA SYFRAVDDTY QYGLSARGLA
210 220 230 240 250
IDTYTDSKEE FPDFTAFWFD TVKPGATTFT VYALLDSASI TGAYKFTIHC
260 270 280 290 300
EKSQVIMDVE NHLYARKDIK QLGIAPMTSM FSCGTNERRM CDTIHPQIHD
310 320 330 340 350
SDRLSMWRGN GEWICRPLNN PQKLQFNAYT DNNPKGFGLL QLDRDFSHYQ
360 370 380 390 400
DIMGWYNKRP SLWVEPRNKW GKGTIGLMEI PTTGETLDNI VCFWQPEKAV
410 420 430 440 450
KAGDEFAFQY RLYWSAQPPV HCPLARVMAT RTGMGGFSEG WAPGEHYPEK
460 470 480 490 500
WARRFAVDFV GGDLKAAAPK GIEPVITLSS GEAKQIEILY IEPIDGYRIQ
510 520 530 540 550
FDWYPTSDST DPVDMRMYLR CQGDAISETW LYQYFPPAPD KRQYVDDRVM

S
Length:551
Mass (Da):62,758
Last modified:July 3, 2003 - v3
Checksum:i4FC3BE21F70D4C46
GO

Sequence cautioni

The sequence BAA15046 differs from that shown. Reason: Erroneous initiation.Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U00096 Genomic DNA Translation: AAC74506.3
AP009048 Genomic DNA Translation: BAA15046.1 Different initiation.
X15860 Genomic DNA No translation available.
PIRiC64894
RefSeqiNP_415941.5, NC_000913.3
WP_000375961.1, NZ_LN832404.1

Genome annotation databases

EnsemblBacteriaiAAC74506; AAC74506; b1424
BAA15046; BAA15046; BAA15046
GeneIDi945994
KEGGiecj:JW1420
eco:b1424
PATRICifig|511145.12.peg.1487

Similar proteinsi

Entry informationi

Entry nameiOPGD_ECOLI
AccessioniPrimary (citable) accession number: P40120
Secondary accession number(s): P46134, P76098, P77631
Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 1, 1995
Last sequence update: July 3, 2003
Last modified: March 28, 2018
This is version 131 of the entry and version 3 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Direct protein sequencing, Reference proteome

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