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P40108

- ALDH_DAVTA

UniProt

P40108 - ALDH_DAVTA

Protein

Aldehyde dehydrogenase

Gene

CLAH10

Organism
Davidiella tassiana (Mycosphaerella tassiana) (Cladosporium herbarum)
Status
Reviewed - Annotation score: 2 out of 5- Experimental evidence at protein leveli
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    • History
      Entry version 76 (01 Oct 2014)
      Sequence version 2 (13 Jun 2006)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    An aldehyde + NAD+ + H2O = a carboxylate + NADH.

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Active sitei263 – 2631By similarity
    Active sitei296 – 2961By similarity

    GO - Molecular functioni

    1. aldehyde dehydrogenase (NAD) activity Source: UniProtKB-EC

    Keywords - Molecular functioni

    Oxidoreductase

    Keywords - Ligandi

    NAD

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Aldehyde dehydrogenase (EC:1.2.1.3)
    Short name:
    ALDDH
    Short name:
    ALDH
    Alternative name(s):
    Allergen Cla h 3
    Allergen Cla h III
    Allergen: Cla h 10
    Gene namesi
    Name:CLAH10
    Synonyms:CLAH3
    OrganismiDavidiella tassiana (Mycosphaerella tassiana) (Cladosporium herbarum)
    Taxonomic identifieri29918 [NCBI]
    Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaPezizomycotinaDothideomycetesDothideomycetidaeCapnodialesCladosporiaceaeCladosporium

    Subcellular locationi

    Cytoplasm Curated

    GO - Cellular componenti

    1. cytoplasm Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Cytoplasm

    Pathology & Biotechi

    Allergenic propertiesi

    Causes an allergic reaction in human.1 Publication

    Keywords - Diseasei

    Allergen

    Protein family/group databases

    Allergomei218. Cla h 10.
    3201. Cla h 10.0101.

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 496496Aldehyde dehydrogenasePRO_0000056437Add
    BLAST

    Proteomic databases

    PRIDEiP40108.

    Structurei

    3D structure databases

    ProteinModelPortaliP40108.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the aldehyde dehydrogenase family.Curated

    Family and domain databases

    Gene3Di3.40.309.10. 1 hit.
    3.40.605.10. 1 hit.
    InterProiIPR016161. Ald_DH/histidinol_DH.
    IPR016163. Ald_DH_C.
    IPR016160. Ald_DH_CS_CYS.
    IPR029510. Ald_DH_CS_GLU.
    IPR016162. Ald_DH_N.
    IPR015590. Aldehyde_DH_dom.
    IPR015657. Aminobutyraldehyde_DH.
    [Graphical view]
    PANTHERiPTHR11699:SF46. PTHR11699:SF46. 1 hit.
    PfamiPF00171. Aldedh. 1 hit.
    [Graphical view]
    SUPFAMiSSF53720. SSF53720. 1 hit.
    PROSITEiPS00070. ALDEHYDE_DEHYDR_CYS. 1 hit.
    PS00687. ALDEHYDE_DEHYDR_GLU. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    P40108-1 [UniParc]FASTAAdd to Basket

    « Hide

    MTSVQLETPH SGKYEQPTGL FINNEFVKGQ EGKTFDVINP SDESVITQVH    50
    EATEKDVDIA VAAARKAFEG SWRQETPENR GKLLNNLANL FEKNIDLLAA 100
    VESLDNGKAI SMAKGDISMC VGCLRYYGGW ADKITGKVID TTPDTFNYVK 150
    KEPIGVCGQI IPWNFPLLMW AWKIGPAIAC GNTVVLKTAE QTPLGGLVAA 200
    SLVKEAGFPP GVINVISGFG KVAGAALSSH MDVDKVAFTG STVVGRTILK 250
    AAASSNLKKV TLELGGKSPN IVFEDADIDN AISWVNFGIF FNHGQCCCAG 300
    SRVYVQESIY DKFVQKFKER AQKNVVGDPF AADTFQGPQV SKVQFDRIME 350
    YIQAGKDAGA TVETGGKRKG DKGYFIEPTI FSNVTEDMKI VKEEIFGPVC 400
    SIAKFKTKED AIKLGNASTY GLAAAVHTKN LNTAIEVSNA LKAGTVWVNT 450
    YNTLHHQMPF GGYKESGIGR ELGEDALANY TQTKTVSIRL GDALFG 496
    Length:496
    Mass (Da):53,554
    Last modified:June 13, 2006 - v2
    Checksum:iD938B5D0D9B26999
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    X78228 mRNA. Translation: CAA55072.2.
    PIRiS43114.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    X78228 mRNA. Translation: CAA55072.2 .
    PIRi S43114.

    3D structure databases

    ProteinModelPortali P40108.
    ModBasei Search...
    MobiDBi Search...

    Protein family/group databases

    Allergomei 218. Cla h 10.
    3201. Cla h 10.0101.

    Proteomic databases

    PRIDEi P40108.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Family and domain databases

    Gene3Di 3.40.309.10. 1 hit.
    3.40.605.10. 1 hit.
    InterProi IPR016161. Ald_DH/histidinol_DH.
    IPR016163. Ald_DH_C.
    IPR016160. Ald_DH_CS_CYS.
    IPR029510. Ald_DH_CS_GLU.
    IPR016162. Ald_DH_N.
    IPR015590. Aldehyde_DH_dom.
    IPR015657. Aminobutyraldehyde_DH.
    [Graphical view ]
    PANTHERi PTHR11699:SF46. PTHR11699:SF46. 1 hit.
    Pfami PF00171. Aldedh. 1 hit.
    [Graphical view ]
    SUPFAMi SSF53720. SSF53720. 1 hit.
    PROSITEi PS00070. ALDEHYDE_DEHYDR_CYS. 1 hit.
    PS00687. ALDEHYDE_DEHYDR_GLU. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Molecular cloning of major and minor allergens of Alternaria alternata and Cladosporium herbarum."
      Achatz G., Oberkofler H., Lechenauer E., Simon-Nobbe B., Unger A., Kandler D., Ebner C., Prillinger H., Kraft D., Breitenbach M.
      Mol. Immunol. 32:213-227(1995) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [MRNA], ALLERGEN.
      Strain: 280202-Berlin.
    2. Simon-Nobbe B.
      Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases
      Cited for: SEQUENCE REVISION TO 66; 74; 95; 110; 114-121; 158-165 AND 367.

    Entry informationi

    Entry nameiALDH_DAVTA
    AccessioniPrimary (citable) accession number: P40108
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: February 1, 1995
    Last sequence update: June 13, 2006
    Last modified: October 1, 2014
    This is version 76 of the entry and version 2 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programFungal Protein Annotation Program

    Miscellaneousi

    Documents

    1. Allergens
      Nomenclature of allergens and list of entries
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3