SubmitCancel

Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

P40081

- MGDP1_YEAST

UniProt

P40081 - MGDP1_YEAST

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein
Putative magnesium-dependent phosphatase YER134C
Gene
YER134C
Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed - Annotation score: 4 out of 5 - Experimental evidence at protein leveli

Functioni

Magnesium-dependent phosphatase which may act as a tyrosine phosphatase By similarity.

Catalytic activityi

Protein tyrosine phosphate + H2O = protein tyrosine + phosphate.

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei11 – 111Nucleophile By similarity
Metal bindingi11 – 111Magnesium By similarity
Binding sitei12 – 121Phosphate; via amide nitrogen By similarity
Active sitei13 – 131Proton donor By similarity
Metal bindingi13 – 131Magnesium By similarity
Binding sitei13 – 131Phosphate; via amide nitrogen By similarity
Binding sitei74 – 741Phosphate By similarity
Binding sitei75 – 751Phosphate By similarity
Binding sitei75 – 751Substrate By similarity
Metal bindingi141 – 1411Magnesium By similarity

GO - Molecular functioni

  1. acid phosphatase activity Source: SGD
  2. metal ion binding Source: UniProtKB-KW
  3. protein tyrosine phosphatase activity, metal-dependent Source: SGD

GO - Biological processi

  1. dephosphorylation Source: GOC
  2. peptidyl-tyrosine dephosphorylation Source: GOC
Complete GO annotation...

Keywords - Molecular functioni

Hydrolase, Protein phosphatase

Keywords - Ligandi

Magnesium, Metal-binding

Enzyme and pathway databases

BioCyciYEAST:G3O-30296-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Putative magnesium-dependent phosphatase YER134C (EC:3.1.3.48)
Gene namesi
Ordered Locus Names:YER134C
OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Taxonomic identifieri559292 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
ProteomesiUP000002311: Chromosome V

Organism-specific databases

CYGDiYER134c.
SGDiS000000936. YER134C.

Subcellular locationi

Cytoplasm. Nucleus 1 Publication

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
  2. nucleus Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm, Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 178178Putative magnesium-dependent phosphatase YER134C
PRO_0000202650Add
BLAST

Proteomic databases

MaxQBiP40081.
PaxDbiP40081.
PeptideAtlasiP40081.

Expressioni

Gene expression databases

GenevestigatoriP40081.

Interactioni

Protein-protein interaction databases

BioGridi36880. 14 interactions.
IntActiP40081. 21 interactions.
MINTiMINT-4484417.
STRINGi4932.YER134C.

Structurei

3D structure databases

ProteinModelPortaliP40081.
SMRiP40081. Positions 1-163.

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiNOG314346.
GeneTreeiENSGT00390000004110.
HOGENOMiHOG000216653.
KOiK17619.
OMAiCWCDTHI.
OrthoDBiEOG718KQX.

Family and domain databases

Gene3Di3.40.50.1000. 1 hit.
InterProiIPR023214. HAD-like_dom.
IPR010033. HAD_SF_ppase_IIIC.
IPR024734. MDP_1_eu.
IPR010036. MDP_1_eu_arc.
[Graphical view]
PANTHERiPTHR17901. PTHR17901. 1 hit.
PfamiPF12689. Acid_PPase. 1 hit.
[Graphical view]
SUPFAMiSSF56784. SSF56784. 1 hit.
TIGRFAMsiTIGR01681. HAD-SF-IIIC. 1 hit.
TIGR01685. MDP-1. 1 hit.

Sequencei

Sequence statusi: Complete.

P40081-1 [UniParc]FASTAAdd to Basket

« Hide

MTGYPDVAAF DLDYTIWPCY CDTHLHGPFK PVKSSNGEVL TIICRDGYEL    50
TIYKDIPRIL GDLKDNGVKL MTASRTWAPE IAQEILKIFK VKYAGVVTPL 100
ANLFDEFQWG ERSKIGHLRD GLKDLYNTSD LKSKKICLFD DESRNKEVEK 150
YGVKFVYVRD PENGPSWKLY QDYLSGKV 178
Length:178
Mass (Da):20,441
Last modified:February 1, 1995 - v1
Checksum:iF3F765AC0076CBFC
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
U18916 Genomic DNA. Translation: AAC03232.1.
AY558562 Genomic DNA. Translation: AAS56888.1.
BK006939 Genomic DNA. Translation: DAA07794.1.
PIRiS50637.
RefSeqiNP_011060.1. NM_001179024.1.

Genome annotation databases

EnsemblFungiiYER134C; YER134C; YER134C.
GeneIDi856873.
KEGGisce:YER134C.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
U18916 Genomic DNA. Translation: AAC03232.1 .
AY558562 Genomic DNA. Translation: AAS56888.1 .
BK006939 Genomic DNA. Translation: DAA07794.1 .
PIRi S50637.
RefSeqi NP_011060.1. NM_001179024.1.

3D structure databases

ProteinModelPortali P40081.
SMRi P40081. Positions 1-163.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

BioGridi 36880. 14 interactions.
IntActi P40081. 21 interactions.
MINTi MINT-4484417.
STRINGi 4932.YER134C.

Proteomic databases

MaxQBi P40081.
PaxDbi P40081.
PeptideAtlasi P40081.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblFungii YER134C ; YER134C ; YER134C .
GeneIDi 856873.
KEGGi sce:YER134C.

Organism-specific databases

CYGDi YER134c.
SGDi S000000936. YER134C.

Phylogenomic databases

eggNOGi NOG314346.
GeneTreei ENSGT00390000004110.
HOGENOMi HOG000216653.
KOi K17619.
OMAi CWCDTHI.
OrthoDBi EOG718KQX.

Enzyme and pathway databases

BioCyci YEAST:G3O-30296-MONOMER.

Miscellaneous databases

NextBioi 983247.
PROi P40081.

Gene expression databases

Genevestigatori P40081.

Family and domain databases

Gene3Di 3.40.50.1000. 1 hit.
InterProi IPR023214. HAD-like_dom.
IPR010033. HAD_SF_ppase_IIIC.
IPR024734. MDP_1_eu.
IPR010036. MDP_1_eu_arc.
[Graphical view ]
PANTHERi PTHR17901. PTHR17901. 1 hit.
Pfami PF12689. Acid_PPase. 1 hit.
[Graphical view ]
SUPFAMi SSF56784. SSF56784. 1 hit.
TIGRFAMsi TIGR01681. HAD-SF-IIIC. 1 hit.
TIGR01685. MDP-1. 1 hit.
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 204508 / S288c.
  2. Cited for: GENOME REANNOTATION.
    Strain: ATCC 204508 / S288c.
  3. Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
    Strain: ATCC 204508 / S288c.
  4. Cited for: SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS].
  5. Cited for: LEVEL OF PROTEIN EXPRESSION [LARGE SCALE ANALYSIS].

Entry informationi

Entry nameiMGDP1_YEAST
AccessioniPrimary (citable) accession number: P40081
Secondary accession number(s): D3DM40
Entry historyi
Integrated into UniProtKB/Swiss-Prot: February 1, 1995
Last sequence update: February 1, 1995
Last modified: May 14, 2014
This is version 95 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Miscellaneous

Present with 6190 molecules/cell in log phase SD medium.

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Yeast
    Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD
  3. Yeast chromosome V
    Yeast (Saccharomyces cerevisiae) chromosome V: entries and gene names

External Data

Dasty 3

Similar proteinsi