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Protein

Protein DSE1

Gene

DSE1

Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Involved in cell wall metabolism and required for the separation of the mother and daughter cells.1 Publication

Miscellaneous

Present with 3080 molecules/cell in log phase SD medium.1 Publication

GO - Biological processi

  • cell cycle Source: UniProtKB-KW
  • cell separation after cytokinesis Source: SGD
  • cell wall organization Source: UniProtKB-KW
  • invasive growth in response to glucose limitation Source: SGD
  • regulation of pheromone-dependent signal transduction involved in conjugation with cellular fusion Source: SGD

Keywordsi

Biological processCell cycle, Cell division, Cell wall biogenesis/degradation

Enzyme and pathway databases

BioCyciYEAST:G3O-30287-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Protein DSE1
Alternative name(s):
Daughter-specific expression protein 1
Gene namesi
Name:DSE1
Ordered Locus Names:YER124C
ORF Names:SYGP-ORF48
OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Taxonomic identifieri559292 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
Proteomesi
  • UP000002311 Componenti: Chromosome V

Organism-specific databases

EuPathDBiFungiDB:YER124C
SGDiS000000926 DSE1

Subcellular locationi

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002026471 – 573Protein DSE1Add BLAST573

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Cross-linki553Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin)Combined sources

Keywords - PTMi

Isopeptide bond, Ubl conjugation

Proteomic databases

MaxQBiP40077
PaxDbiP40077
PRIDEiP40077

PTM databases

iPTMnetiP40077

Expressioni

Developmental stagei

Expressed in daughter cells.1 Publication

Inductioni

Expressed periodically during cell division. Requires ACE2, CBK1, MOB2 and SWI5. Expression is also increased under microgravity conditions.4 Publications

Interactioni

Binary interactionsi

WithEntry#Exp.IntActNotes
BOI2P399693EBI-22676,EBI-3727

Protein-protein interaction databases

BioGridi36868, 90 interactors
DIPiDIP-2585N
IntActiP40077, 5 interactors
MINTiP40077
STRINGi4932.YER124C

Structurei

3D structure databases

ProteinModelPortaliP40077
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Repeati144 – 185WD 1Add BLAST42
Repeati315 – 351WD 2Add BLAST37
Repeati356 – 395WD 3Add BLAST40
Repeati397 – 448WD 4Add BLAST52

Sequence similaritiesi

Belongs to the WD repeat DSE1 family.Curated

Keywords - Domaini

Repeat, WD repeat

Phylogenomic databases

HOGENOMiHOG000112282
InParanoidiP40077
OMAiTLLFRQN
OrthoDBiEOG092C1LLR

Family and domain databases

InterProiView protein in InterPro
IPR001680 WD40_repeat
IPR036322 WD40_repeat_dom_sf
SMARTiView protein in SMART
SM00320 WD40, 2 hits
SUPFAMiSSF50978 SSF50978, 1 hit

Sequencei

Sequence statusi: Complete.

P40077-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MQDTKYYEPT NIFRQPAINI KKRSDKKRIL QSMMTLSTYK KTWQNNTSKM
60 70 80 90 100
NSPILRKASD NFNDYYTTKK LKSDYWKLYG VDESELSIPS DMSIVDNILL
110 120 130 140 150
VSTMNEKDNL KLFEISAEKK LKELQTITVP GKPITCICLL PMVDFPPQIF
160 170 180 190 200
PSSQINPNHN QLILTGHQDG IVNLIATSTY KGCAKIIKRF NHNKFLKSTV
210 220 230 240 250
STSIPILEIT PKTAPILKVS PWNKTGFVSL LNDSLFIYDL KSNLDCIKTP
260 270 280 290 300
IFLQSYPGIN SFAVNEFHDP FLLALVGSKF GPNGISLLDL RTNLYIPDIL
310 320 330 340 350
DNSISAGCGK DHLQRKNTSL DCVWISNHHV AQSLNDKIQI WDIQSCDGKP
360 370 380 390 400
VCELYAKKGY IESLKFNENT GALYSSDDQG FVICWDLQNL QNMKYGELVH
410 420 430 440 450
GFNSISLDSE SELLLTKQVF QCGNIIVSGM SDKNICLKSN DTKANGKGCG
460 470 480 490 500
FLFLDMANDG SLVTLDNFCE LGLHQICQVQ FNVDTGKIID GNGTGKSGIS
510 520 530 540 550
DSSMLSLSNE SDHSMTETSD DMFSNSGNWD CSSANTVSEG RLNDDQEDIV
560 570
FTKRMYSVND VHLSGSTIDT TVV
Length:573
Mass (Da):63,999
Last modified:February 1, 1995 - v1
Checksum:iD5FE871E7C76B260
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U18916 Genomic DNA Translation: AAC03222.1
BK006939 Genomic DNA Translation: DAA07784.1
PIRiS50627
RefSeqiNP_011050.3, NM_001179014.3

Genome annotation databases

EnsemblFungiiYER124C; YER124C; YER124C
GeneIDi856861
KEGGisce:YER124C

Similar proteinsi

Entry informationi

Entry nameiDSE1_YEAST
AccessioniPrimary (citable) accession number: P40077
Secondary accession number(s): D3DM30
Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 1, 1995
Last sequence update: February 1, 1995
Last modified: March 28, 2018
This is version 138 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Yeast
    Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD
  3. Yeast chromosome V
    Yeast (Saccharomyces cerevisiae) chromosome V: entries and gene names

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