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Protein

Regulator of Ty1 transposition protein 105

Gene

RTT105

Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

Involved in regulation of Ty1 transposition. Inhibits Ty1 transposition at a post-transcriptional and pre-integrational stage of the Ty1 retrotransposition cycle.1 Publication

GO - Biological processi

  1. negative regulation of transposition, RNA-mediated Source: SGD
  2. transposition Source: UniProtKB-KW
Complete GO annotation...

Keywords - Biological processi

Transposition

Enzyme and pathway databases

BioCyciYEAST:G3O-30269-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Regulator of Ty1 transposition protein 105
Gene namesi
Name:RTT105
Ordered Locus Names:YER104W
OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Taxonomic identifieri559292 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
ProteomesiUP000002311: Chromosome V

Organism-specific databases

CYGDiYER104w.
SGDiS000000906. RTT105.

Subcellular locationi

Cytoplasm 1 Publication. Nucleus 1 Publication

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
  2. nucleus Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm, Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 208208Regulator of Ty1 transposition protein 105PRO_0000202644Add
BLAST

Proteomic databases

PaxDbiP40063.

Expressioni

Gene expression databases

GenevestigatoriP40063.

Interactioni

Protein-protein interaction databases

BioGridi36850. 26 interactions.
DIPiDIP-2766N.
IntActiP40063. 3 interactions.
MINTiMINT-486951.
STRINGi4932.YER104W.

Structurei

3D structure databases

ProteinModelPortaliP40063.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

eggNOGiNOG136304.
InParanoidiP40063.
OrthoDBiEOG7JHMJB.

Sequencei

Sequence statusi: Complete.

P40063-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MYSNHNLNSD DCCFDWNEEK AAELQRTGVS FDRSLTPQSL RTSTRRLSEE
60 70 80 90 100
NKQQSGTMHI DTSPSVVSDI ISSRRDRSQD FFGPHSSSPI APSERQRADQ
110 120 130 140 150
RSRLESMRLT RRRDKMTKVR GGLEKMEEMI MQGEHLREMQ RLKQEAQKNA
160 170 180 190 200
LPSDMAEYME WQNNEDLEDD ELLAFIEKQE TYKNELEHFL NNANKNVYEN

NSYPNSHT
Length:208
Mass (Da):24,413
Last modified:February 1, 1995 - v1
Checksum:iFE14F6F48E8232E7
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U18839 Genomic DNA. Translation: AAB64659.1.
AY692872 Genomic DNA. Translation: AAT92891.1.
BK006939 Genomic DNA. Translation: DAA07765.1.
PIRiS50607.
RefSeqiNP_011030.3. NM_001178995.3.

Genome annotation databases

EnsemblFungiiYER104W; YER104W; YER104W.
GeneIDi856841.
KEGGisce:YER104W.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U18839 Genomic DNA. Translation: AAB64659.1.
AY692872 Genomic DNA. Translation: AAT92891.1.
BK006939 Genomic DNA. Translation: DAA07765.1.
PIRiS50607.
RefSeqiNP_011030.3. NM_001178995.3.

3D structure databases

ProteinModelPortaliP40063.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi36850. 26 interactions.
DIPiDIP-2766N.
IntActiP40063. 3 interactions.
MINTiMINT-486951.
STRINGi4932.YER104W.

Proteomic databases

PaxDbiP40063.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblFungiiYER104W; YER104W; YER104W.
GeneIDi856841.
KEGGisce:YER104W.

Organism-specific databases

CYGDiYER104w.
SGDiS000000906. RTT105.

Phylogenomic databases

eggNOGiNOG136304.
InParanoidiP40063.
OrthoDBiEOG7JHMJB.

Enzyme and pathway databases

BioCyciYEAST:G3O-30269-MONOMER.

Miscellaneous databases

NextBioi983156.

Gene expression databases

GenevestigatoriP40063.

Family and domain databases

ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 204508 / S288c.
  2. Cited for: GENOME REANNOTATION.
    Strain: ATCC 204508 / S288c.
  3. Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
    Strain: ATCC 204508 / S288c.
  4. "Multiple regulators of Ty1 transposition in Saccharomyces cerevisiae have conserved roles in genome maintenance."
    Scholes D.T., Banerjee M., Bowen B., Curcio M.J.
    Genetics 159:1449-1465(2001) [PubMed] [Europe PMC] [Abstract]
    Cited for: FUNCTION.
  5. Cited for: SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS].
  6. Cited for: LEVEL OF PROTEIN EXPRESSION [LARGE SCALE ANALYSIS].
  7. "A multidimensional chromatography technology for in-depth phosphoproteome analysis."
    Albuquerque C.P., Smolka M.B., Payne S.H., Bafna V., Eng J., Zhou H.
    Mol. Cell. Proteomics 7:1389-1396(2008) [PubMed] [Europe PMC] [Abstract]
    Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
  8. "Global analysis of Cdk1 substrate phosphorylation sites provides insights into evolution."
    Holt L.J., Tuch B.B., Villen J., Johnson A.D., Gygi S.P., Morgan D.O.
    Science 325:1682-1686(2009) [PubMed] [Europe PMC] [Abstract]
    Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].

Entry informationi

Entry nameiRT105_YEAST
AccessioniPrimary (citable) accession number: P40063
Secondary accession number(s): D3DM11
Entry historyi
Integrated into UniProtKB/Swiss-Prot: February 1, 1995
Last sequence update: February 1, 1995
Last modified: January 7, 2015
This is version 92 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Miscellaneous

Present with 259 molecules/cell in log phase SD medium.1 Publication

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Yeast
    Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD
  2. Yeast chromosome V
    Yeast (Saccharomyces cerevisiae) chromosome V: entries and gene names

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.