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P40060

- IES5_YEAST

UniProt

P40060 - IES5_YEAST

Protein

Ino eighty subunit 5

Gene

IES5

Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed - Annotation score: 3 out of 5- Experimental evidence at protein leveli
  1. Functioni

    GO - Molecular functioni

    1. protein binding Source: IntAct

    GO - Biological processi

    1. telomere maintenance via recombination Source: SGD

    Enzyme and pathway databases

    BioCyciYEAST:G3O-30259-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Ino eighty subunit 5
    Gene namesi
    Name:IES5
    Ordered Locus Names:YER092W
    OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
    Taxonomic identifieri559292 [NCBI]
    Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
    ProteomesiUP000002311: Chromosome V

    Organism-specific databases

    CYGDiYER092w.
    SGDiS000000894. IES5.

    Subcellular locationi

    Nucleus 1 Publication

    GO - Cellular componenti

    1. Ino80 complex Source: SGD

    Keywords - Cellular componenti

    Nucleus

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 125125Ino eighty subunit 5PRO_0000084157Add
    BLAST

    Amino acid modifications

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Modified residuei124 – 1241Phosphothreonine2 Publications

    Keywords - PTMi

    Phosphoprotein

    Proteomic databases

    MaxQBiP40060.
    PaxDbiP40060.

    Expressioni

    Gene expression databases

    GenevestigatoriP40060.

    Interactioni

    Subunit structurei

    Component of the chromatin-remodeling INO80 complex, at least composed of ARP4, ARP5, ARP8, RVB1, RVB2, TAF14, NHP10, IES1, IES3, IES4, IES6, ACT1, IES2, IES5 and INO80.1 Publication

    Binary interactionsi

    WithEntry#Exp.IntActNotes
    IES3Q123453EBI-22617,EBI-35758
    NHP10Q034355EBI-22617,EBI-12010

    Protein-protein interaction databases

    BioGridi36837. 170 interactions.
    DIPiDIP-1468N.
    IntActiP40060. 19 interactions.
    MINTiMINT-412117.
    STRINGi4932.YER092W.

    Structurei

    3D structure databases

    ProteinModelPortaliP40060.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Phylogenomic databases

    eggNOGiNOG82552.
    HOGENOMiHOG000000842.
    KOiK11679.
    OMAiTPLLYKD.
    OrthoDBiEOG7V1G43.

    Family and domain databases

    InterProiIPR020366. Ies5.
    [Graphical view]
    ProDomiPD079054. Ino_eighty_subunit_5. 1 hit.
    [Graphical view] [Entries sharing at least one domain]

    Sequencei

    Sequence statusi: Complete.

    P40060-1 [UniParc]FASTAAdd to Basket

    « Hide

    MPSKDPESVI DKEIRKISAR NDELIKQDGT LKREYTTLLR KVSSVITVLN    50
    SIDDADTGSA ETELPRLISQ ATVEKVPELK WYNDQISLIT EKLEDDEDIE 100
    VPEELMDAYT LYKETPLLYN DTHTP 125
    Length:125
    Mass (Da):14,312
    Last modified:February 1, 1995 - v1
    Checksum:i777B96A00E9FF6E2
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    U32508 Genomic DNA. Translation: AAB60299.1.
    U18839 Genomic DNA. Translation: AAB64647.1.
    BK006939 Genomic DNA. Translation: DAA07753.1.
    PIRiS50595.
    RefSeqiNP_011017.3. NM_001178983.3.

    Genome annotation databases

    EnsemblFungiiYER092W; YER092W; YER092W.
    GeneIDi856827.
    KEGGisce:YER092W.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    U32508 Genomic DNA. Translation: AAB60299.1 .
    U18839 Genomic DNA. Translation: AAB64647.1 .
    BK006939 Genomic DNA. Translation: DAA07753.1 .
    PIRi S50595.
    RefSeqi NP_011017.3. NM_001178983.3.

    3D structure databases

    ProteinModelPortali P40060.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    BioGridi 36837. 170 interactions.
    DIPi DIP-1468N.
    IntActi P40060. 19 interactions.
    MINTi MINT-412117.
    STRINGi 4932.YER092W.

    Proteomic databases

    MaxQBi P40060.
    PaxDbi P40060.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblFungii YER092W ; YER092W ; YER092W .
    GeneIDi 856827.
    KEGGi sce:YER092W.

    Organism-specific databases

    CYGDi YER092w.
    SGDi S000000894. IES5.

    Phylogenomic databases

    eggNOGi NOG82552.
    HOGENOMi HOG000000842.
    KOi K11679.
    OMAi TPLLYKD.
    OrthoDBi EOG7V1G43.

    Enzyme and pathway databases

    BioCyci YEAST:G3O-30259-MONOMER.

    Miscellaneous databases

    NextBioi 983118.

    Gene expression databases

    Genevestigatori P40060.

    Family and domain databases

    InterProi IPR020366. Ies5.
    [Graphical view ]
    ProDomi PD079054. Ino_eighty_subunit_5. 1 hit.
    [Graphical view ] [Entries sharing at least one domain ]
    ProtoNeti Search...

    Publicationsi

    1. Korch C., Mountain H.A., Wenzlau J.M.
      Submitted (OCT-1995) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
      Strain: ATCC 204508 / S288c.
    2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC 204508 / S288c.
    3. Cited for: GENOME REANNOTATION.
      Strain: ATCC 204508 / S288c.
    4. Cited for: SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS].
    5. Cited for: LEVEL OF PROTEIN EXPRESSION [LARGE SCALE ANALYSIS].
    6. "Involvement of actin-related proteins in ATP-dependent chromatin remodeling."
      Shen X., Ranallo R., Choi E., Wu C.
      Mol. Cell 12:147-155(2003) [PubMed] [Europe PMC] [Abstract]
      Cited for: IDENTIFICATION IN THE INO80 COMPLEX.
    7. "A multidimensional chromatography technology for in-depth phosphoproteome analysis."
      Albuquerque C.P., Smolka M.B., Payne S.H., Bafna V., Eng J., Zhou H.
      Mol. Cell. Proteomics 7:1389-1396(2008) [PubMed] [Europe PMC] [Abstract]
      Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT THR-124, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
    8. "Global analysis of Cdk1 substrate phosphorylation sites provides insights into evolution."
      Holt L.J., Tuch B.B., Villen J., Johnson A.D., Gygi S.P., Morgan D.O.
      Science 325:1682-1686(2009) [PubMed] [Europe PMC] [Abstract]
      Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT THR-124, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
    9. Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].

    Entry informationi

    Entry nameiIES5_YEAST
    AccessioniPrimary (citable) accession number: P40060
    Secondary accession number(s): D3DLZ9
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: February 1, 1995
    Last sequence update: February 1, 1995
    Last modified: October 1, 2014
    This is version 100 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programFungal Protein Annotation Program

    Miscellaneousi

    Miscellaneous

    Present with 2280 molecules/cell in log phase SD medium.1 Publication

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. Yeast
      Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD
    2. Yeast chromosome V
      Yeast (Saccharomyces cerevisiae) chromosome V: entries and gene names

    External Data

    Dasty 3