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P40055

- UTP7_YEAST

UniProt

P40055 - UTP7_YEAST

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Protein

U3 small nucleolar RNA-associated protein 7

Gene
UTP7, KRE31, YER082C
Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed - Annotation score: 4 out of 5 - Experimental evidence at protein leveli

Functioni

Involved in nucleolar processing of pre-18S ribosomal RNA.1 Publication

GO - Biological processi

  1. endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) Source: SGD
  2. endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) Source: SGD
  3. endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA) Source: SGD
  4. maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) Source: SGD
Complete GO annotation...

Keywords - Molecular functioni

Ribonucleoprotein

Keywords - Biological processi

Ribosome biogenesis, rRNA processing

Enzyme and pathway databases

BioCyciYEAST:G3O-30252-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
U3 small nucleolar RNA-associated protein 7
Short name:
U3 snoRNA-associated protein 7
Alternative name(s):
U three protein 7
Gene namesi
Name:UTP7
Synonyms:KRE31
Ordered Locus Names:YER082C
OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Taxonomic identifieri559292 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
ProteomesiUP000002311: Chromosome V

Organism-specific databases

CYGDiYER082c.
SGDiS000000884. UTP7.

Subcellular locationi

Nucleusnucleolus 1 Publication

GO - Cellular componenti

  1. nucleolus Source: SGD
  2. small-subunit processome Source: SGD
Complete GO annotation...

Keywords - Cellular componenti

Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 554554U3 small nucleolar RNA-associated protein 7PRO_0000051319Add
BLAST

Proteomic databases

MaxQBiP40055.
PaxDbiP40055.
PeptideAtlasiP40055.

Expressioni

Gene expression databases

GenevestigatoriP40055.

Interactioni

Subunit structurei

Interacts with snoRNA U3. Interacts with MPP10. Component of the ribosomal small subunit (SSU) processome composed of at least 40 protein subunits and snoRNA U3.1 Publication

Protein-protein interaction databases

BioGridi36827. 82 interactions.
DIPiDIP-5398N.
IntActiP40055. 48 interactions.
MINTiMINT-513710.
STRINGi4932.YER082C.

Structurei

3D structure databases

ProteinModelPortaliP40055.
SMRiP40055. Positions 95-182, 203-368.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Repeati108 – 14942WD 1Add
BLAST
Repeati230 – 26940WD 2Add
BLAST
Repeati272 – 31140WD 3Add
BLAST
Repeati314 – 35138WD 4Add
BLAST

Sequence similaritiesi

Contains 4 WD repeats.

Keywords - Domaini

Repeat, WD repeat

Phylogenomic databases

eggNOGiNOG301990.
GeneTreeiENSGT00390000007075.
HOGENOMiHOG000165037.
KOiK14768.
OMAiNVIDQRK.
OrthoDBiEOG786HCW.

Family and domain databases

Gene3Di2.130.10.10. 1 hit.
InterProiIPR012952. BING4_C_dom.
IPR015943. WD40/YVTN_repeat-like_dom.
IPR001680. WD40_repeat.
IPR019775. WD40_repeat_CS.
IPR017986. WD40_repeat_dom.
[Graphical view]
PfamiPF08149. BING4CT. 1 hit.
PF00400. WD40. 1 hit.
[Graphical view]
SMARTiSM01033. BING4CT. 1 hit.
SM00320. WD40. 3 hits.
[Graphical view]
SUPFAMiSSF50978. SSF50978. 1 hit.
PROSITEiPS00678. WD_REPEATS_1. 1 hit.
PS50082. WD_REPEATS_2. 1 hit.
PS50294. WD_REPEATS_REGION. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P40055-1 [UniParc]FASTAAdd to Basket

« Hide

MGHKKNGHRR QIKERENQNK FERSTYTNNA KNNHTQTKDK KLRAGLKKID    50
EQYKKAVSSA AATDYLLPES NGYLEPENEL EKTFKVQQSE IKSSVDVSTA 100
NKALDLSLKE FGPYHIKYAK NGTHLLITGR KGHVASMDWR KGQLRAELFL 150
NETCHSATYL QNEQYFAVAQ KKYTFIYDHE GTELHRLKQH IEARHLDFLP 200
YHYLLVTAGE TGWLKYHDVS TGQLVSELRT KAGPTMAMAQ NPWNAVMHLG 250
HSNGTVSLWS PSMPEPLVKL LSARGPVNSI AIDRSGYYMA TTGADRSMKI 300
WDIRNFKQLH SVESLPTPGT NVSISDTGLL ALSRGPHVTL WKDALKLSGD 350
SKPCFGSMGG NPHRNTPYMS HLFAGNKVEN LGFVPFEDLL GVGHQTGITN 400
LIVPGAGEAN YDALELNPFE TKKQRQEQEV RTLLNKLPAD TITLDPNSIG 450
SVDKRSSTIR LNAKDLAQTT MDANNKAKTN SDIPDVKPDV KGKNSGLRSF 500
LRKKTQNVID ERKLRVQKQL DKEKNIRKRN HQIKQGLISE DHKDVIEEAL 550
SRFG 554
Length:554
Mass (Da):62,317
Last modified:February 1, 1995 - v1
Checksum:iA254AD9AC1142AA5
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
U18839 Genomic DNA. Translation: AAB64637.1.
BK006939 Genomic DNA. Translation: DAA07743.1.
PIRiS50585.
RefSeqiNP_011005.1. NM_001178973.1.

Genome annotation databases

EnsemblFungiiYER082C; YER082C; YER082C.
GeneIDi856815.
KEGGisce:YER082C.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
U18839 Genomic DNA. Translation: AAB64637.1 .
BK006939 Genomic DNA. Translation: DAA07743.1 .
PIRi S50585.
RefSeqi NP_011005.1. NM_001178973.1.

3D structure databases

ProteinModelPortali P40055.
SMRi P40055. Positions 95-182, 203-368.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

BioGridi 36827. 82 interactions.
DIPi DIP-5398N.
IntActi P40055. 48 interactions.
MINTi MINT-513710.
STRINGi 4932.YER082C.

Proteomic databases

MaxQBi P40055.
PaxDbi P40055.
PeptideAtlasi P40055.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblFungii YER082C ; YER082C ; YER082C .
GeneIDi 856815.
KEGGi sce:YER082C.

Organism-specific databases

CYGDi YER082c.
SGDi S000000884. UTP7.

Phylogenomic databases

eggNOGi NOG301990.
GeneTreei ENSGT00390000007075.
HOGENOMi HOG000165037.
KOi K14768.
OMAi NVIDQRK.
OrthoDBi EOG786HCW.

Enzyme and pathway databases

BioCyci YEAST:G3O-30252-MONOMER.

Miscellaneous databases

NextBioi 983088.
PROi P40055.

Gene expression databases

Genevestigatori P40055.

Family and domain databases

Gene3Di 2.130.10.10. 1 hit.
InterProi IPR012952. BING4_C_dom.
IPR015943. WD40/YVTN_repeat-like_dom.
IPR001680. WD40_repeat.
IPR019775. WD40_repeat_CS.
IPR017986. WD40_repeat_dom.
[Graphical view ]
Pfami PF08149. BING4CT. 1 hit.
PF00400. WD40. 1 hit.
[Graphical view ]
SMARTi SM01033. BING4CT. 1 hit.
SM00320. WD40. 3 hits.
[Graphical view ]
SUPFAMi SSF50978. SSF50978. 1 hit.
PROSITEi PS00678. WD_REPEATS_1. 1 hit.
PS50082. WD_REPEATS_2. 1 hit.
PS50294. WD_REPEATS_REGION. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 204508 / S288c.
  2. Cited for: GENOME REANNOTATION.
    Strain: ATCC 204508 / S288c.
  3. Cited for: FUNCTION, INTERACTION WITH MPP10 AND SNORNA U3, IDENTIFICATION IN SSU PROCESSOME BY MASS SPECTROMETRY, SUBCELLULAR LOCATION.
  4. Cited for: LEVEL OF PROTEIN EXPRESSION [LARGE SCALE ANALYSIS].

Entry informationi

Entry nameiUTP7_YEAST
AccessioniPrimary (citable) accession number: P40055
Secondary accession number(s): D3DLY9
Entry historyi
Integrated into UniProtKB/Swiss-Prot: February 1, 1995
Last sequence update: February 1, 1995
Last modified: June 11, 2014
This is version 122 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Miscellaneous

Present with 5800 molecules/cell in log phase SD medium.

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Yeast
    Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD
  3. Yeast chromosome V
    Yeast (Saccharomyces cerevisiae) chromosome V: entries and gene names

External Data

Dasty 3