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P40055 (UTP7_YEAST) Reviewed, UniProtKB/Swiss-Prot

Last modified June 11, 2014. Version 122. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (3) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
U3 small nucleolar RNA-associated protein 7

Short name=U3 snoRNA-associated protein 7
Alternative name(s):
U three protein 7
Gene names
Name:UTP7
Synonyms:KRE31
Ordered Locus Names:YER082C
OrganismSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) [Reference proteome]
Taxonomic identifier559292 [NCBI]
Taxonomic lineageEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces

Protein attributes

Sequence length554 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

General annotation (Comments)

Function

Involved in nucleolar processing of pre-18S ribosomal RNA. Ref.3

Subunit structure

Interacts with snoRNA U3. Interacts with MPP10. Component of the ribosomal small subunit (SSU) processome composed of at least 40 protein subunits and snoRNA U3. Ref.3

Subcellular location

Nucleusnucleolus Ref.3.

Miscellaneous

Present with 5800 molecules/cell in log phase SD medium.

Sequence similarities

Contains 4 WD repeats.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 554554U3 small nucleolar RNA-associated protein 7
PRO_0000051319

Regions

Repeat108 – 14942WD 1
Repeat230 – 26940WD 2
Repeat272 – 31140WD 3
Repeat314 – 35138WD 4

Sequences

Sequence LengthMass (Da)Tools
P40055 [UniParc].

Last modified February 1, 1995. Version 1.
Checksum: A254AD9AC1142AA5

FASTA55462,317
        10         20         30         40         50         60 
MGHKKNGHRR QIKERENQNK FERSTYTNNA KNNHTQTKDK KLRAGLKKID EQYKKAVSSA 

        70         80         90        100        110        120 
AATDYLLPES NGYLEPENEL EKTFKVQQSE IKSSVDVSTA NKALDLSLKE FGPYHIKYAK 

       130        140        150        160        170        180 
NGTHLLITGR KGHVASMDWR KGQLRAELFL NETCHSATYL QNEQYFAVAQ KKYTFIYDHE 

       190        200        210        220        230        240 
GTELHRLKQH IEARHLDFLP YHYLLVTAGE TGWLKYHDVS TGQLVSELRT KAGPTMAMAQ 

       250        260        270        280        290        300 
NPWNAVMHLG HSNGTVSLWS PSMPEPLVKL LSARGPVNSI AIDRSGYYMA TTGADRSMKI 

       310        320        330        340        350        360 
WDIRNFKQLH SVESLPTPGT NVSISDTGLL ALSRGPHVTL WKDALKLSGD SKPCFGSMGG 

       370        380        390        400        410        420 
NPHRNTPYMS HLFAGNKVEN LGFVPFEDLL GVGHQTGITN LIVPGAGEAN YDALELNPFE 

       430        440        450        460        470        480 
TKKQRQEQEV RTLLNKLPAD TITLDPNSIG SVDKRSSTIR LNAKDLAQTT MDANNKAKTN 

       490        500        510        520        530        540 
SDIPDVKPDV KGKNSGLRSF LRKKTQNVID ERKLRVQKQL DKEKNIRKRN HQIKQGLISE 

       550 
DHKDVIEEAL SRFG 

« Hide

References

« Hide 'large scale' references
[1]"The nucleotide sequence of Saccharomyces cerevisiae chromosome V."
Dietrich F.S., Mulligan J.T., Hennessy K.M., Yelton M.A., Allen E., Araujo R., Aviles E., Berno A., Brennan T., Carpenter J., Chen E., Cherry J.M., Chung E., Duncan M., Guzman E., Hartzell G., Hunicke-Smith S., Hyman R.W. expand/collapse author list , Kayser A., Komp C., Lashkari D., Lew H., Lin D., Mosedale D., Nakahara K., Namath A., Norgren R., Oefner P., Oh C., Petel F.X., Roberts D., Sehl P., Schramm S., Shogren T., Smith V., Taylor P., Wei Y., Botstein D., Davis R.W.
Nature 387:78-81(1997) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 204508 / S288c.
[2]"The reference genome sequence of Saccharomyces cerevisiae: Then and now."
Engel S.R., Dietrich F.S., Fisk D.G., Binkley G., Balakrishnan R., Costanzo M.C., Dwight S.S., Hitz B.C., Karra K., Nash R.S., Weng S., Wong E.D., Lloyd P., Skrzypek M.S., Miyasato S.R., Simison M., Cherry J.M.
G3 (Bethesda) 4:389-398(2014) [PubMed] [Europe PMC] [Abstract]
Cited for: GENOME REANNOTATION.
Strain: ATCC 204508 / S288c.
[3]"A large nucleolar U3 ribonucleoprotein required for 18S ribosomal RNA biogenesis."
Dragon F., Gallagher J.E.G., Compagnone-Post P.A., Mitchell B.M., Porwancher K.A., Wehner K.A., Wormsley S., Settlage R.E., Shabanowitz J., Osheim Y., Beyer A.L., Hunt D.F., Baserga S.J.
Nature 417:967-970(2002) [PubMed] [Europe PMC] [Abstract]
Cited for: FUNCTION, INTERACTION WITH MPP10 AND SNORNA U3, IDENTIFICATION IN SSU PROCESSOME BY MASS SPECTROMETRY, SUBCELLULAR LOCATION.
[4]"Global analysis of protein expression in yeast."
Ghaemmaghami S., Huh W.-K., Bower K., Howson R.W., Belle A., Dephoure N., O'Shea E.K., Weissman J.S.
Nature 425:737-741(2003) [PubMed] [Europe PMC] [Abstract]
Cited for: LEVEL OF PROTEIN EXPRESSION [LARGE SCALE ANALYSIS].
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
U18839 Genomic DNA. Translation: AAB64637.1.
BK006939 Genomic DNA. Translation: DAA07743.1.
PIRS50585.
RefSeqNP_011005.1. NM_001178973.1.

3D structure databases

ProteinModelPortalP40055.
SMRP40055. Positions 95-182, 203-368.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

BioGrid36827. 82 interactions.
DIPDIP-5398N.
IntActP40055. 48 interactions.
MINTMINT-513710.
STRING4932.YER082C.

Proteomic databases

MaxQBP40055.
PaxDbP40055.
PeptideAtlasP40055.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblFungiYER082C; YER082C; YER082C.
GeneID856815.
KEGGsce:YER082C.

Organism-specific databases

CYGDYER082c.
SGDS000000884. UTP7.

Phylogenomic databases

eggNOGNOG301990.
GeneTreeENSGT00390000007075.
HOGENOMHOG000165037.
KOK14768.
OMANVIDQRK.
OrthoDBEOG786HCW.

Enzyme and pathway databases

BioCycYEAST:G3O-30252-MONOMER.

Gene expression databases

GenevestigatorP40055.

Family and domain databases

Gene3D2.130.10.10. 1 hit.
InterProIPR012952. BING4_C_dom.
IPR015943. WD40/YVTN_repeat-like_dom.
IPR001680. WD40_repeat.
IPR019775. WD40_repeat_CS.
IPR017986. WD40_repeat_dom.
[Graphical view]
PfamPF08149. BING4CT. 1 hit.
PF00400. WD40. 1 hit.
[Graphical view]
SMARTSM01033. BING4CT. 1 hit.
SM00320. WD40. 3 hits.
[Graphical view]
SUPFAMSSF50978. SSF50978. 1 hit.
PROSITEPS00678. WD_REPEATS_1. 1 hit.
PS50082. WD_REPEATS_2. 1 hit.
PS50294. WD_REPEATS_REGION. 1 hit.
[Graphical view]
ProtoNetSearch...

Other

NextBio983088.
PROP40055.

Entry information

Entry nameUTP7_YEAST
AccessionPrimary (citable) accession number: P40055
Secondary accession number(s): D3DLY9
Entry history
Integrated into UniProtKB/Swiss-Prot: February 1, 1995
Last sequence update: February 1, 1995
Last modified: June 11, 2014
This is version 122 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Relevant documents

Yeast chromosome V

Yeast (Saccharomyces cerevisiae) chromosome V: entries and gene names

Yeast

Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD

SIMILARITY comments

Index of protein domains and families