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Protein

U3 small nucleolar RNA-associated protein 7

Gene

UTP7

Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed-Annotation score: Annotation score: 5 out of 5-Experimental evidence at protein leveli

Functioni

Involved in nucleolar processing of pre-18S ribosomal RNA.1 Publication

Miscellaneous

Present with 5800 molecules/cell in log phase SD medium.1 Publication

GO - Biological processi

Keywordsi

Molecular functionRibonucleoprotein
Biological processRibosome biogenesis, rRNA processing

Enzyme and pathway databases

BioCyciYEAST:G3O-30252-MONOMER.
ReactomeiR-SCE-6790901. rRNA modification in the nucleus and cytosol.
R-SCE-6791226. Major pathway of rRNA processing in the nucleolus and cytosol.

Names & Taxonomyi

Protein namesi
Recommended name:
U3 small nucleolar RNA-associated protein 7
Short name:
U3 snoRNA-associated protein 7
Alternative name(s):
U three protein 7
Gene namesi
Name:UTP7
Synonyms:KRE31
Ordered Locus Names:YER082C
OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Taxonomic identifieri559292 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
Proteomesi
  • UP000002311 Componenti: Chromosome V

Organism-specific databases

EuPathDBiFungiDB:YER082C.
SGDiS000000884. UTP7.

Subcellular locationi

GO - Cellular componenti

  • nucleolus Source: SGD
  • nucleoplasm Source: Reactome
  • preribosome, small subunit precursor Source: GO_Central
  • small-subunit processome Source: SGD

Keywords - Cellular componenti

Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000513191 – 554U3 small nucleolar RNA-associated protein 7Add BLAST554

Proteomic databases

MaxQBiP40055.
PRIDEiP40055.

Interactioni

Subunit structurei

Interacts with snoRNA U3. Interacts with MPP10. Component of the ribosomal small subunit (SSU) processome composed of at least 40 protein subunits and snoRNA U3.1 Publication

Protein-protein interaction databases

BioGridi36827. 247 interactors.
DIPiDIP-5398N.
IntActiP40055. 48 interactors.
MINTiMINT-513710.
STRINGi4932.YER082C.

Structurei

3D structure databases

ProteinModelPortaliP40055.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Repeati108 – 149WD 1Add BLAST42
Repeati230 – 269WD 2Add BLAST40
Repeati272 – 311WD 3Add BLAST40
Repeati314 – 351WD 4Add BLAST38

Keywords - Domaini

Repeat, WD repeat

Phylogenomic databases

GeneTreeiENSGT00390000007075.
HOGENOMiHOG000165037.
InParanoidiP40055.
KOiK14768.
OMAiREGRYMV.
OrthoDBiEOG092C27NP.

Family and domain databases

Gene3Di2.130.10.10. 1 hit.
InterProiView protein in InterPro
IPR012952. BING4_C_dom.
IPR015943. WD40/YVTN_repeat-like_dom.
IPR001680. WD40_repeat.
IPR019775. WD40_repeat_CS.
IPR017986. WD40_repeat_dom.
PfamiView protein in Pfam
PF08149. BING4CT. 1 hit.
SMARTiView protein in SMART
SM01033. BING4CT. 1 hit.
SM00320. WD40. 3 hits.
SUPFAMiSSF50978. SSF50978. 1 hit.
PROSITEiView protein in PROSITE
PS00678. WD_REPEATS_1. 1 hit.
PS50082. WD_REPEATS_2. 1 hit.
PS50294. WD_REPEATS_REGION. 1 hit.

Sequencei

Sequence statusi: Complete.

P40055-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGHKKNGHRR QIKERENQNK FERSTYTNNA KNNHTQTKDK KLRAGLKKID
60 70 80 90 100
EQYKKAVSSA AATDYLLPES NGYLEPENEL EKTFKVQQSE IKSSVDVSTA
110 120 130 140 150
NKALDLSLKE FGPYHIKYAK NGTHLLITGR KGHVASMDWR KGQLRAELFL
160 170 180 190 200
NETCHSATYL QNEQYFAVAQ KKYTFIYDHE GTELHRLKQH IEARHLDFLP
210 220 230 240 250
YHYLLVTAGE TGWLKYHDVS TGQLVSELRT KAGPTMAMAQ NPWNAVMHLG
260 270 280 290 300
HSNGTVSLWS PSMPEPLVKL LSARGPVNSI AIDRSGYYMA TTGADRSMKI
310 320 330 340 350
WDIRNFKQLH SVESLPTPGT NVSISDTGLL ALSRGPHVTL WKDALKLSGD
360 370 380 390 400
SKPCFGSMGG NPHRNTPYMS HLFAGNKVEN LGFVPFEDLL GVGHQTGITN
410 420 430 440 450
LIVPGAGEAN YDALELNPFE TKKQRQEQEV RTLLNKLPAD TITLDPNSIG
460 470 480 490 500
SVDKRSSTIR LNAKDLAQTT MDANNKAKTN SDIPDVKPDV KGKNSGLRSF
510 520 530 540 550
LRKKTQNVID ERKLRVQKQL DKEKNIRKRN HQIKQGLISE DHKDVIEEAL

SRFG
Length:554
Mass (Da):62,317
Last modified:February 1, 1995 - v1
Checksum:iA254AD9AC1142AA5
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U18839 Genomic DNA. Translation: AAB64637.1.
BK006939 Genomic DNA. Translation: DAA07743.1.
PIRiS50585.
RefSeqiNP_011005.1. NM_001178973.1.

Genome annotation databases

EnsemblFungiiYER082C; YER082C; YER082C.
GeneIDi856815.
KEGGisce:YER082C.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.

Entry informationi

Entry nameiUTP7_YEAST
AccessioniPrimary (citable) accession number: P40055
Secondary accession number(s): D3DLY9
Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 1, 1995
Last sequence update: February 1, 1995
Last modified: July 5, 2017
This is version 147 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Yeast
    Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD
  2. Yeast chromosome V
    Yeast (Saccharomyces cerevisiae) chromosome V: entries and gene names