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Protein

U3 small nucleolar RNA-associated protein 7

Gene

UTP7

Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed-Annotation score: Annotation score: 4 out of 5-Experimental evidence at protein leveli

Functioni

Involved in nucleolar processing of pre-18S ribosomal RNA.1 Publication

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Ribonucleoprotein

Keywords - Biological processi

Ribosome biogenesis, rRNA processing

Enzyme and pathway databases

BioCyciYEAST:G3O-30252-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
U3 small nucleolar RNA-associated protein 7
Short name:
U3 snoRNA-associated protein 7
Alternative name(s):
U three protein 7
Gene namesi
Name:UTP7
Synonyms:KRE31
Ordered Locus Names:YER082C
OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Taxonomic identifieri559292 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
ProteomesiUP000002311 Componenti: Chromosome V

Organism-specific databases

CYGDiYER082c.
EuPathDBiFungiDB:YER082C.
SGDiS000000884. UTP7.

Subcellular locationi

GO - Cellular componenti

  • nucleolus Source: SGD
  • preribosome, small subunit precursor Source: GO_Central
  • small-subunit processome Source: SGD
Complete GO annotation...

Keywords - Cellular componenti

Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 554554U3 small nucleolar RNA-associated protein 7PRO_0000051319Add
BLAST

Proteomic databases

MaxQBiP40055.
PaxDbiP40055.
PeptideAtlasiP40055.

Expressioni

Gene expression databases

GenevestigatoriP40055.

Interactioni

Subunit structurei

Interacts with snoRNA U3. Interacts with MPP10. Component of the ribosomal small subunit (SSU) processome composed of at least 40 protein subunits and snoRNA U3.1 Publication

Protein-protein interaction databases

BioGridi36827. 83 interactions.
DIPiDIP-5398N.
IntActiP40055. 48 interactions.
MINTiMINT-513710.
STRINGi4932.YER082C.

Structurei

3D structure databases

ProteinModelPortaliP40055.
SMRiP40055. Positions 95-182, 203-368.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Repeati108 – 14942WD 1Add
BLAST
Repeati230 – 26940WD 2Add
BLAST
Repeati272 – 31140WD 3Add
BLAST
Repeati314 – 35138WD 4Add
BLAST

Sequence similaritiesi

Contains 4 WD repeats.PROSITE-ProRule annotation

Keywords - Domaini

Repeat, WD repeat

Phylogenomic databases

eggNOGiNOG301990.
GeneTreeiENSGT00390000007075.
HOGENOMiHOG000165037.
InParanoidiP40055.
KOiK14768.
OMAiELHCLNK.
OrthoDBiEOG786HCW.

Family and domain databases

Gene3Di2.130.10.10. 1 hit.
InterProiIPR012952. BING4_C_dom.
IPR015943. WD40/YVTN_repeat-like_dom.
IPR001680. WD40_repeat.
IPR019775. WD40_repeat_CS.
IPR017986. WD40_repeat_dom.
[Graphical view]
PfamiPF08149. BING4CT. 1 hit.
PF00400. WD40. 1 hit.
[Graphical view]
SMARTiSM01033. BING4CT. 1 hit.
SM00320. WD40. 3 hits.
[Graphical view]
SUPFAMiSSF50978. SSF50978. 1 hit.
PROSITEiPS00678. WD_REPEATS_1. 1 hit.
PS50082. WD_REPEATS_2. 1 hit.
PS50294. WD_REPEATS_REGION. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P40055-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGHKKNGHRR QIKERENQNK FERSTYTNNA KNNHTQTKDK KLRAGLKKID
60 70 80 90 100
EQYKKAVSSA AATDYLLPES NGYLEPENEL EKTFKVQQSE IKSSVDVSTA
110 120 130 140 150
NKALDLSLKE FGPYHIKYAK NGTHLLITGR KGHVASMDWR KGQLRAELFL
160 170 180 190 200
NETCHSATYL QNEQYFAVAQ KKYTFIYDHE GTELHRLKQH IEARHLDFLP
210 220 230 240 250
YHYLLVTAGE TGWLKYHDVS TGQLVSELRT KAGPTMAMAQ NPWNAVMHLG
260 270 280 290 300
HSNGTVSLWS PSMPEPLVKL LSARGPVNSI AIDRSGYYMA TTGADRSMKI
310 320 330 340 350
WDIRNFKQLH SVESLPTPGT NVSISDTGLL ALSRGPHVTL WKDALKLSGD
360 370 380 390 400
SKPCFGSMGG NPHRNTPYMS HLFAGNKVEN LGFVPFEDLL GVGHQTGITN
410 420 430 440 450
LIVPGAGEAN YDALELNPFE TKKQRQEQEV RTLLNKLPAD TITLDPNSIG
460 470 480 490 500
SVDKRSSTIR LNAKDLAQTT MDANNKAKTN SDIPDVKPDV KGKNSGLRSF
510 520 530 540 550
LRKKTQNVID ERKLRVQKQL DKEKNIRKRN HQIKQGLISE DHKDVIEEAL

SRFG
Length:554
Mass (Da):62,317
Last modified:February 1, 1995 - v1
Checksum:iA254AD9AC1142AA5
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U18839 Genomic DNA. Translation: AAB64637.1.
BK006939 Genomic DNA. Translation: DAA07743.1.
PIRiS50585.
RefSeqiNP_011005.1. NM_001178973.1.

Genome annotation databases

EnsemblFungiiYER082C; YER082C; YER082C.
GeneIDi856815.
KEGGisce:YER082C.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U18839 Genomic DNA. Translation: AAB64637.1.
BK006939 Genomic DNA. Translation: DAA07743.1.
PIRiS50585.
RefSeqiNP_011005.1. NM_001178973.1.

3D structure databases

ProteinModelPortaliP40055.
SMRiP40055. Positions 95-182, 203-368.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi36827. 83 interactions.
DIPiDIP-5398N.
IntActiP40055. 48 interactions.
MINTiMINT-513710.
STRINGi4932.YER082C.

Proteomic databases

MaxQBiP40055.
PaxDbiP40055.
PeptideAtlasiP40055.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblFungiiYER082C; YER082C; YER082C.
GeneIDi856815.
KEGGisce:YER082C.

Organism-specific databases

CYGDiYER082c.
EuPathDBiFungiDB:YER082C.
SGDiS000000884. UTP7.

Phylogenomic databases

eggNOGiNOG301990.
GeneTreeiENSGT00390000007075.
HOGENOMiHOG000165037.
InParanoidiP40055.
KOiK14768.
OMAiELHCLNK.
OrthoDBiEOG786HCW.

Enzyme and pathway databases

BioCyciYEAST:G3O-30252-MONOMER.

Miscellaneous databases

NextBioi983088.
PROiP40055.

Gene expression databases

GenevestigatoriP40055.

Family and domain databases

Gene3Di2.130.10.10. 1 hit.
InterProiIPR012952. BING4_C_dom.
IPR015943. WD40/YVTN_repeat-like_dom.
IPR001680. WD40_repeat.
IPR019775. WD40_repeat_CS.
IPR017986. WD40_repeat_dom.
[Graphical view]
PfamiPF08149. BING4CT. 1 hit.
PF00400. WD40. 1 hit.
[Graphical view]
SMARTiSM01033. BING4CT. 1 hit.
SM00320. WD40. 3 hits.
[Graphical view]
SUPFAMiSSF50978. SSF50978. 1 hit.
PROSITEiPS00678. WD_REPEATS_1. 1 hit.
PS50082. WD_REPEATS_2. 1 hit.
PS50294. WD_REPEATS_REGION. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 204508 / S288c.
  2. Cited for: GENOME REANNOTATION.
    Strain: ATCC 204508 / S288c.
  3. Cited for: FUNCTION, INTERACTION WITH MPP10 AND SNORNA U3, IDENTIFICATION IN SSU PROCESSOME BY MASS SPECTROMETRY, SUBCELLULAR LOCATION.
  4. Cited for: LEVEL OF PROTEIN EXPRESSION [LARGE SCALE ANALYSIS].

Entry informationi

Entry nameiUTP7_YEAST
AccessioniPrimary (citable) accession number: P40055
Secondary accession number(s): D3DLY9
Entry historyi
Integrated into UniProtKB/Swiss-Prot: February 1, 1995
Last sequence update: February 1, 1995
Last modified: May 27, 2015
This is version 128 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Miscellaneous

Present with 5800 molecules/cell in log phase SD medium.1 Publication

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Yeast
    Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD
  3. Yeast chromosome V
    Yeast (Saccharomyces cerevisiae) chromosome V: entries and gene names

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.