P40053 (AIM9_YEAST) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Altered inheritance of mitochondria protein 9, mitochondrial

Alternative name(s):
Found in mitochondrial proteome protein 29

Gene names

Name:	AIM9
Synonyms:	FMP29
Ordered Locus Names:	YER080W

Organism

Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) [Reference proteome]

Taxonomic identifier

559292 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Fungi › Dikarya › Ascomycota › saccharomyceta › Saccharomycotina › Saccharomycetes › Saccharomycetales › Saccharomycetaceae › Saccharomyces › Saccharomyces cerevisiae

Protein attributes

Sequence length	627 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is further processed into a mature form.
Protein existence	Evidence at protein level

General annotation (Comments)

Subcellular location	Mitochondrion Ref.3 Ref.5.
Disruption phenotype	Increases frequency of mitochondrial genome loss. Ref.6
Miscellaneous	Present with 8200 molecules/cell in log phase SD medium.
Sequence similarities	Belongs to the AIM9 family.

Ontologies

Keywords
Cellular component	Mitochondrion
Domain	Transit peptide
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Cellular_component	mitochondrion Inferred from direct assay Ref.3PubMed 14576278Ref.5. Source: SGD
Molecular_function	transferase activity, transferring phosphorus-containing groups Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Binary interactions

With	Entry	#Exp.	IntAct	Notes
SSA2	P10592	1	EBI-22593,EBI-8603

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Transit peptide	1 – 43	43	Mitochondrion Potential
	Chain	44 – 627	584	Altered inheritance of mitochondria protein 9, mitochondrial		PRO_0000202637

Sequences

	Sequence		Length	Mass (Da)
	P40053 [UniParc]. Last modified February 1, 1995. Version 1. Checksum: 395479DDEC0F4F51	FASTA	627	72,414
	10 20 30 40 50 60 MIRYTVAGHS RRCVVGASKR VGAIKCITVA ATKRFISNKP NEVFTKLTND NDPKRDAFFK 70 80 90 100 110 120 YTWGSWLKND KQEKEKRFTK FSIEGLNRIL NDIYIQSNEM AKAPDGKILP PVFNKNLTVS 130 140 150 160 170 180 LVNNVVPKNI GKINPNEKVQ VTTLSSIHEG KHHRIYKVDT NLNKAFILRI PYPLENENTL 190 200 210 220 230 240 SYRIRSEVAT MDFADLKLGI KVPKIFCYGV NSLNPVRQPF VLQEFIEGEL LMKDWDPLIE 250 260 270 280 290 300 DGSSNQKKYD NVIKQVSDFQ SKLVSLKLNA FGSIYFNNDL KDGNEKEFVK EDIYDGETNP 310 320 330 340 350 360 DLQNRWKIGP SVERCLWRHK SHLDFHKQMK PFLGPWPKKS PMDIIKNTGL LEAENAKTRI 370 380 390 400 410 420 AMKEAGSSAE LMYPRTLKEQ ITTYENLAKI APDLFNVKTK AIPNMQELLS PRLFHPDLDP 430 440 450 460 470 480 MNIIVNKEAQ EAYLLDFEGA CTKPFILQNS PQFIAYDGPK IYDLKEDITD FDKLSEAEKV 490 500 510 520 530 540 QYQFMYKRTR NQHQWEKKLN DNNPKLITAV APPVKLLRSP YIAAVERKTE EEYLLIDESL 550 560 570 580 590 600 LQLKEVWDIF AQNELVNQKK FPLNYSKEDI ERHVEDLQKL HEKLISTPFA ATQGWIPQDM 610 620 FDQLLNSGSI VKQENGDYTV KQPEATK

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"The nucleotide sequence of Saccharomyces cerevisiae chromosome V." Dietrich F.S., Mulligan J.T., Hennessy K.M., Yelton M.A., Allen E., Araujo R., Aviles E., Berno A., Brennan T., Carpenter J., Chen E., Cherry J.M., Chung E., Duncan M., Guzman E., Hartzell G., Hunicke-Smith S., Hyman R.W. , Kayser A., Komp C., Lashkari D., Lew H., Lin D., Mosedale D., Nakahara K., Namath A., Norgren R., Oefner P., Oh C., Petel F.X., Roberts D., Sehl P., Schramm S., Shogren T., Smith V., Taylor P., Wei Y., Botstein D., Davis R.W. Nature 387:78-81(1997) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 204511 / S288c / AB972.
[2]	Saccharomyces Genome Database Submitted (DEC-2009) to the EMBL/GenBank/DDBJ databases Cited for: GENOME REANNOTATION. Strain: ATCC 204508 / S288c.
[3]	"Global analysis of protein localization in budding yeast." Huh W.-K., Falvo J.V., Gerke L.C., Carroll A.S., Howson R.W., Weissman J.S., O'Shea E.K. Nature 425:686-691(2003) [PubMed] [Europe PMC] [Abstract] Cited for: SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS].
[4]	"Global analysis of protein expression in yeast." Ghaemmaghami S., Huh W.-K., Bower K., Howson R.W., Belle A., Dephoure N., O'Shea E.K., Weissman J.S. Nature 425:737-741(2003) [PubMed] [Europe PMC] [Abstract] Cited for: LEVEL OF PROTEIN EXPRESSION [LARGE SCALE ANALYSIS].
[5]	"Toward the complete yeast mitochondrial proteome: multidimensional separation techniques for mitochondrial proteomics." Reinders J., Zahedi R.P., Pfanner N., Meisinger C., Sickmann A. J. Proteome Res. 5:1543-1554(2006) [PubMed] [Europe PMC] [Abstract] Cited for: SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS], MASS SPECTROMETRY.
[6]	"Computationally driven, quantitative experiments discover genes required for mitochondrial biogenesis." Hess D.C., Myers C.L., Huttenhower C., Hibbs M.A., Hayes A.P., Paw J., Clore J.J., Mendoza R.M., Luis B.S., Nislow C., Giaever G., Costanzo M., Troyanskaya O.G., Caudy A.A. PLoS Genet. 5:E1000407-E1000407(2009) [PubMed] [Europe PMC] [Abstract] Cited for: DISRUPTION PHENOTYPE.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	U18839 Genomic DNA. Translation: AAB64635.1. BK006939 Genomic DNA. Translation: DAA07741.1.
PIR	S50583.
RefSeq	NP_011003.1. NM_001178971.1.
3D structure databases
ProteinModelPortal	P40053.
ModBase	Search...
Protein-protein interaction databases
IntAct	P40053. 1 interaction.
STRING	4932.YER080W.
Proteomic databases
PaxDb	P40053.
PeptideAtlas	P40053.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblFungi	YER080W; YER080W; YER080W.
GeneID	856813.
KEGG	sce:YER080W.
Organism-specific databases
CYGD	YER080w.
SGD	S000000882. AIM9.
Phylogenomic databases
eggNOG	NOG42226.
HOGENOM	HOG000246542.
OMA	HEGKHHR.
OrthoDB	EOG42JS11.
Gene expression databases
Genevestigator	P40053.
GermOnline	YER080W. Saccharomyces cerevisiae.
Family and domain databases
InterPro	IPR002575. Aminoglycoside_PTrfase. IPR011009. Kinase-like_dom. [Graphical view]
Pfam	PF01636. APH. 1 hit. [Graphical view]
SUPFAM	SSF56112. Kinase_like. 1 hit.
ProtoNet	Search...
Other
NextBio	983082.

Entry information

Entry name

AIM9_YEAST

Accession

Primary (citable) accession number: P40053
Secondary accession number(s): D3DLY7

Entry history

Integrated into UniProtKB/Swiss-Prot:	February 1, 1995
Last sequence update:	February 1, 1995
Last modified:	April 3, 2013
This is version 80 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Fungal Protein Annotation Program