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P40041

- VHR2_YEAST

UniProt

P40041 - VHR2_YEAST

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Protein
Transcription factor VHR2
Gene
VHR2, YER064C
Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed - Annotation score: 3 out of 5 - Experimental evidence at protein leveli

Functioni

Transcription factor that regulates ERG9, but seems to have a more global function in transcription.2 Publications

GO - Molecular functioni

  1. DNA binding Source: UniProtKB-KW

GO - Biological processi

  1. regulation of transcription, DNA-templated Source: SGD
  2. transcription, DNA-templated Source: UniProtKB-KW
Complete GO annotation...

Keywords - Biological processi

Transcription, Transcription regulation

Keywords - Ligandi

DNA-binding

Enzyme and pathway databases

BioCyciYEAST:G3O-30239-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Transcription factor VHR2
Alternative name(s):
VHT1 regulator 2
Gene namesi
Name:VHR2
Ordered Locus Names:YER064C
OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Taxonomic identifieri559292 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
ProteomesiUP000002311: Chromosome V

Organism-specific databases

CYGDiYER064c.
SGDiS000000866. VHR2.

Subcellular locationi

Nucleus 1 Publication

GO - Cellular componenti

  1. nucleus Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 505505Transcription factor VHR2
PRO_0000202632Add
BLAST

Proteomic databases

MaxQBiP40041.
PaxDbiP40041.

Expressioni

Gene expression databases

GenevestigatoriP40041.

Interactioni

Protein-protein interaction databases

BioGridi36806. 24 interactions.
DIPiDIP-4619N.
IntActiP40041. 4 interactions.
MINTiMINT-513670.
STRINGi4932.YER064C.

Structurei

3D structure databases

ProteinModelPortaliP40041.

Family & Domainsi

Sequence similaritiesi

Belongs to the VHR1 family.

Phylogenomic databases

eggNOGiNOG43836.
GeneTreeiENSGT00530000068544.
OrthoDBiEOG7JX3DC.

Family and domain databases

InterProiIPR007147. TF_Vhr.
[Graphical view]
PfamiPF04001. Vhr1. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P40041-1 [UniParc]FASTAAdd to Basket

« Hide

MIDDTENSKI HLEGSHKTGK YTGYGTTHKI RAQLNFNDEK KWKKFSSRRL    50
ELIDSFGLSQ HKASEQDDNI RQIATILRSE FEYPDTFSAE FEKLVTAAVQ 100
SVRRNRKRSK KKLLDSKKKI ARGKVQKIPL SPPSSSNMGS CSASNASSSD 150
EEASVKEEPA EHALPSLNTI TSQKLLPYPN GRTLPPVPTQ VRSLLKKNAS 200
LLRDPSAPYA HGGDEKLQKF DIEDQPLESE QEYDFIAKSI IVEIVNNAIP 250
LPEQIQRDKF IRPNLTKKKG CQSKVVISNN LRKLILSKIH NSRTCLEMSK 300
DERNLDSFAN LETLGKNSLM ASISLVVENS FSHLPSSTKQ YLTERLSSIE 350
FLTILSQRLF MPATRQLFAD LSQEKIQVRV LNLILGSLVK DYGFDASLAP 400
INEIIYHMTL HQYPLVCSNK QSNPMRPHST SEVLSAHSST KDASTPGKEE 450
PRVTRSSTSA DSTIITLPSI EVPNTYDDDR LKMLSAISLQ IENSTFSKPF 500
STISK 505
Length:505
Mass (Da):56,638
Last modified:February 1, 1995 - v1
Checksum:iDF7C3CB5506AC763
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
U18813 Genomic DNA. Translation: AAB64600.1.
BK006939 Genomic DNA. Translation: DAA07723.1.
PIRiS50567.
RefSeqiNP_010986.1. NM_001178955.1.

Genome annotation databases

EnsemblFungiiYER064C; YER064C; YER064C.
GeneIDi856793.
KEGGisce:YER064C.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
U18813 Genomic DNA. Translation: AAB64600.1 .
BK006939 Genomic DNA. Translation: DAA07723.1 .
PIRi S50567.
RefSeqi NP_010986.1. NM_001178955.1.

3D structure databases

ProteinModelPortali P40041.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

BioGridi 36806. 24 interactions.
DIPi DIP-4619N.
IntActi P40041. 4 interactions.
MINTi MINT-513670.
STRINGi 4932.YER064C.

Proteomic databases

MaxQBi P40041.
PaxDbi P40041.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblFungii YER064C ; YER064C ; YER064C .
GeneIDi 856793.
KEGGi sce:YER064C.

Organism-specific databases

CYGDi YER064c.
SGDi S000000866. VHR2.

Phylogenomic databases

eggNOGi NOG43836.
GeneTreei ENSGT00530000068544.
OrthoDBi EOG7JX3DC.

Enzyme and pathway databases

BioCyci YEAST:G3O-30239-MONOMER.

Miscellaneous databases

NextBioi 983027.

Gene expression databases

Genevestigatori P40041.

Family and domain databases

InterProi IPR007147. TF_Vhr.
[Graphical view ]
Pfami PF04001. Vhr1. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 204508 / S288c.
  2. Cited for: GENOME REANNOTATION.
    Strain: ATCC 204508 / S288c.
  3. "Positive and negative regulation of squalene synthase (ERG9), an ergosterol biosynthetic gene, in Saccharomyces cerevisiae."
    Kennedy M.A., Bard M.
    Biochim. Biophys. Acta 1517:177-189(2001) [PubMed] [Europe PMC] [Abstract]
    Cited for: FUNCTION.
  4. Cited for: SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS].
  5. Cited for: LEVEL OF PROTEIN EXPRESSION [LARGE SCALE ANALYSIS].
  6. "Curated collection of yeast transcription factor DNA binding specificity data reveals novel structural and gene regulatory insights."
    Gordan R., Murphy K.F., McCord R.P., Zhu C., Vedenko A., Bulyk M.L.
    Genome Biol. 12:RESEARCH0125.1-RESEARCH0125.18(2011) [PubMed] [Europe PMC] [Abstract]
    Cited for: DNA-BINDING, POSSIBLE FUNCTION.

Entry informationi

Entry nameiVHR2_YEAST
AccessioniPrimary (citable) accession number: P40041
Secondary accession number(s): D3DLW9
Entry historyi
Integrated into UniProtKB/Swiss-Prot: February 1, 1995
Last sequence update: February 1, 1995
Last modified: September 3, 2014
This is version 89 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Miscellaneous

Present with 1730 molecules/cell in log phase SD medium.

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Yeast
    Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD
  3. Yeast chromosome V
    Yeast (Saccharomyces cerevisiae) chromosome V: entries and gene names

External Data

Dasty 3

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