Skip Header

You are using a version of Internet Explorer that may not display all features of this website. Please upgrade to a modern browser.
Contribute Send feedback
Read comments (?) or add your own

P40036 (GIP2_YEAST) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 102. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (3) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Interactions·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
GLC7-interacting protein 2
Gene names
Name:GIP2
Ordered Locus Names:YER054C
OrganismSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) [Reference proteome]
Taxonomic identifier559292 [NCBI]
Taxonomic lineageEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces

Protein attributes

Sequence length548 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

General annotation (Comments)

Subunit structure

Interacts with phosphatase 1 (GLC7). Ref.3

Miscellaneous

Present with 125 molecules/cell in log phase SD medium.

Sequence similarities

Contains 1 CBM21 (carbohydrate binding type-21) domain.

Binary interactions

With

Entry

#Exp.

IntAct

Notes

SHO1P400732EBI-7612,EBI-18140

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 548548GLC7-interacting protein 2
PRO_0000071521

Regions

Domain419 – 534116CBM21

Amino acid modifications

Modified residue511Phosphoserine Ref.7
Modified residue521Phosphothreonine Ref.7
Modified residue1551Phosphoserine Ref.7
Modified residue2211Phosphoserine Ref.5 Ref.7
Modified residue2381Phosphoserine Ref.6

Sequences

Sequence LengthMass (Da)Tools
P40036 [UniParc].

Last modified February 1, 1995. Version 1.
Checksum: B28EE5241989A9BF

FASTA54862,319
        10         20         30         40         50         60 
MYIKAEQKPQ QFERKNEKLD RNKNQQLPDL ETDFKGYRVN SDLYNKERDG STEETLNSLK 

        70         80         90        100        110        120 
FLHKPQRVTQ MRANRFPEEE VQRNTDLNKR IFSAGNDENV DNESGWSKIA AAKNHTSVES 

       130        140        150        160        170        180 
LNGSTRPPFK IELPPLSPKS TVPKSFQAEY PEAKSPGNDM NFEYDEEILI PFAPPVYKKS 

       190        200        210        220        230        240 
GELLKSSLKR RSKSLPTTPG IRSGNGVQAR DGSPMLIRSK SVHFDQAAPV KYFAEDESPI 

       250        260        270        280        290        300 
NVNKTEQHDN CLSFKHKPVN LMVDPEEETK MLSSGLETTS IDDDLTTVAP KGFAHPAKIS 

       310        320        330        340        350        360 
NPNNGKGTNN TKLRKSKRFQ NLLKNRTDMP PSKSNKKFVN GGGAHEISDR NSKNYHVVGL 

       370        380        390        400        410        420 
YSKNFPILSN KNPKSLKLNI FINLSQNKKV FLQELSLYIH RDNNYFSNSS SFYNIPNSHN 

       430        440        450        460        470        480 
GNDCNGVAKG YNAGCTRLIA GRILVKNIFY DKRVVVRYTW DSWRTTHEVE CVYISDGDGI 

       490        500        510        520        530        540 
LPGTNMDIFH FIIDDVSKVD PRGKLEFCIH YSTRNDYERE EYWDNNNGNN YKVDVVMDGF 


NDPFAAAA 

« Hide

References

« Hide 'large scale' references
[1]"The nucleotide sequence of Saccharomyces cerevisiae chromosome V."
Dietrich F.S., Mulligan J.T., Hennessy K.M., Yelton M.A., Allen E., Araujo R., Aviles E., Berno A., Brennan T., Carpenter J., Chen E., Cherry J.M., Chung E., Duncan M., Guzman E., Hartzell G., Hunicke-Smith S., Hyman R.W. expand/collapse author list , Kayser A., Komp C., Lashkari D., Lew H., Lin D., Mosedale D., Nakahara K., Namath A., Norgren R., Oefner P., Oh C., Petel F.X., Roberts D., Sehl P., Schramm S., Shogren T., Smith V., Taylor P., Wei Y., Botstein D., Davis R.W.
Nature 387:78-81(1997) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 204508 / S288c.
[2]Saccharomyces Genome Database
Submitted (DEC-2009) to the EMBL/GenBank/DDBJ databases
Cited for: GENOME REANNOTATION.
Strain: ATCC 204508 / S288c.
[3]Tu J., Song W., Carslon R.
Unpublished observations (MAR-1996)
Cited for: INTERACTION WITH GLC7.
[4]"Global analysis of protein expression in yeast."
Ghaemmaghami S., Huh W.-K., Bower K., Howson R.W., Belle A., Dephoure N., O'Shea E.K., Weissman J.S.
Nature 425:737-741(2003) [PubMed] [Europe PMC] [Abstract]
Cited for: LEVEL OF PROTEIN EXPRESSION [LARGE SCALE ANALYSIS].
[5]"Analysis of phosphorylation sites on proteins from Saccharomyces cerevisiae by electron transfer dissociation (ETD) mass spectrometry."
Chi A., Huttenhower C., Geer L.Y., Coon J.J., Syka J.E.P., Bai D.L., Shabanowitz J., Burke D.J., Troyanskaya O.G., Hunt D.F.
Proc. Natl. Acad. Sci. U.S.A. 104:2193-2198(2007) [PubMed] [Europe PMC] [Abstract]
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-221, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
[6]"A multidimensional chromatography technology for in-depth phosphoproteome analysis."
Albuquerque C.P., Smolka M.B., Payne S.H., Bafna V., Eng J., Zhou H.
Mol. Cell. Proteomics 7:1389-1396(2008) [PubMed] [Europe PMC] [Abstract]
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-238, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
[7]"Global analysis of Cdk1 substrate phosphorylation sites provides insights into evolution."
Holt L.J., Tuch B.B., Villen J., Johnson A.D., Gygi S.P., Morgan D.O.
Science 325:1682-1686(2009) [PubMed] [Europe PMC] [Abstract]
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-51; THR-52; SER-155 AND SER-221, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
[8]"N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB."
Van Damme P., Lasa M., Polevoda B., Gazquez C., Elosegui-Artola A., Kim D.S., De Juan-Pardo E., Demeyer K., Hole K., Larrea E., Timmerman E., Prieto J., Arnesen T., Sherman F., Gevaert K., Aldabe R.
Proc. Natl. Acad. Sci. U.S.A. 109:12449-12454(2012) [PubMed] [Europe PMC] [Abstract]
Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
U18813 Genomic DNA. Translation: AAB64590.1.
BK006939 Genomic DNA. Translation: DAA07711.1.
PIRS50557.
RefSeqNP_010974.1. NM_001178945.1.

3D structure databases

ProteinModelPortalP40036.
SMRP40036. Positions 381-545.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

BioGrid36794. 35 interactions.
DIPDIP-2376N.
IntActP40036. 10 interactions.
MINTMINT-600077.
STRING4932.YER054C.

Protein family/group databases

CAZyCBM21. Carbohydrate-Binding Module Family 21.

Proteomic databases

PaxDbP40036.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblFungiYER054C; YER054C; YER054C.
GeneID856781.
KEGGsce:YER054C.

Organism-specific databases

CYGDYER054c.
SGDS000000856. GIP2.

Phylogenomic databases

eggNOGNOG288354.
GeneTreeENSGT00530000067694.
HOGENOMHOG000112724.
OMARTTHEVE.
OrthoDBEOG7XWPXD.

Enzyme and pathway databases

BioCycYEAST:G3O-30232-MONOMER.

Gene expression databases

GenevestigatorP40036.

Family and domain databases

InterProIPR005036. CBM_21.
IPR016717. Pase-1_int.
[Graphical view]
PfamPF03370. CBM_21. 1 hit.
[Graphical view]
PIRSFPIRSF018234. PPase_interacting. 1 hit.
PROSITEPS51159. CBM21. 1 hit.
[Graphical view]
ProtoNetSearch...

Other

NextBio982991.

Entry information

Entry nameGIP2_YEAST
AccessionPrimary (citable) accession number: P40036
Secondary accession number(s): D3DLV7
Entry history
Integrated into UniProtKB/Swiss-Prot: February 1, 1995
Last sequence update: February 1, 1995
Last modified: April 16, 2014
This is version 102 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Relevant documents

Yeast chromosome V

Yeast (Saccharomyces cerevisiae) chromosome V: entries and gene names

Yeast

Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD

SIMILARITY comments

Index of protein domains and families