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Protein

37S ribosomal protein RSM18, mitochondrial

Gene

RSM18

Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Component of the mitochondrial ribosome (mitoribosome), a dedicated translation machinery responsible for the synthesis of mitochondrial genome-encoded proteins, including at least some of the essential transmembrane subunits of the mitochondrial respiratory chain. The mitoribosomes are attached to the mitochondrial inner membrane and translation products are cotranslationally integrated into the membrane.2 Publications

Miscellaneous

Present with 1210 molecules/cell in log phase SD medium.1 Publication

GO - Molecular functioni

  • structural constituent of ribosome Source: SGD

GO - Biological processi

Keywordsi

Molecular functionRibonucleoprotein, Ribosomal protein

Enzyme and pathway databases

BioCyciYEAST:G3O-30229-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
37S ribosomal protein RSM18, mitochondrial
Alternative name(s):
Mitochondrial small ribosomal subunit protein bS18m1 Publication
Gene namesi
Name:RSM18
Ordered Locus Names:YER050C
OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Taxonomic identifieri559292 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
Proteomesi
  • UP000002311 Componenti: Chromosome V

Organism-specific databases

EuPathDBiFungiDB:YER050C
SGDiS000000852 RSM18

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Mitochondrion

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_0000111318? – 13837S ribosomal protein RSM18, mitochondrial
Transit peptidei1 – ?MitochondrionSequence analysis

Proteomic databases

MaxQBiP40033
PaxDbiP40033
PRIDEiP40033

Interactioni

Subunit structurei

Component of the mitochondrial small ribosomal subunit (mt-SSU). Mature yeast 74S mitochondrial ribosomes consist of a small (37S) and a large (54S) subunit. The 37S small subunit contains a 15S ribosomal RNA (15S mt-rRNA) and 34 different proteins. The 54S large subunit contains a 21S rRNA (21S mt-rRNA) and 46 different proteins.2 Publications

Binary interactionsi

Show more details

Protein-protein interaction databases

BioGridi36789, 44 interactors
IntActiP40033, 37 interactors
MINTiP40033
STRINGi4932.YER050C

Structurei

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
5MRCelectron microscopy3.25RR40-138[»]
5MREelectron microscopy3.75RR40-138[»]
5MRFelectron microscopy4.97RR40-138[»]
ProteinModelPortaliP40033
SMRiP40033
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Keywords - Domaini

Transit peptide

Phylogenomic databases

HOGENOMiHOG000248555
InParanoidiP40033
KOiK02963
OrthoDBiEOG092C52B2

Family and domain databases

Gene3Di4.10.640.10, 1 hit
InterProiView protein in InterPro
IPR001648 Ribosomal_S18
IPR036870 Ribosomal_S18_sf
PfamiView protein in Pfam
PF01084 Ribosomal_S18, 1 hit
PRINTSiPR00974 RIBOSOMALS18
ProDomiView protein in ProDom or Entries sharing at least one domain
PD002239 Ribosomal_S18, 1 hit
SUPFAMiSSF46911 SSF46911, 1 hit

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

P40033-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MQPIIKGAVS STFKRALYNF GIKEKKSVNI EMGRTQQTKK IDQSLSKKLP
60 70 80 90 100
KGTIYDPFDF SMGRIHLDRK YQANKNSNRN DIMKSGANPL EFYARPRILS
110 120 130
RYVTSTGRIQ HRDITGLSAK NQRRLSKAIR RCQAIGLM
Length:138
Mass (Da):15,835
Last modified:June 16, 2009 - v2
Checksum:iF97AB3C8DEC3EF42
GO

Sequence cautioni

The sequence AAB64585 differs from that shown. Reason: Erroneous initiation.Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U18796 Genomic DNA Translation: AAB64585.1 Different initiation.
BK006939 Genomic DNA Translation: DAA07706.1
PIRiS50553
RefSeqiNP_010970.4, NM_001178941.3

Genome annotation databases

EnsemblFungiiYER050C; YER050C; YER050C
GeneIDi856776
KEGGisce:YER050C

Similar proteinsi

Entry informationi

Entry nameiRSM18_YEAST
AccessioniPrimary (citable) accession number: P40033
Secondary accession number(s): D3DLV2
Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 1, 1995
Last sequence update: June 16, 2009
Last modified: March 28, 2018
This is version 130 of the entry and version 2 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome
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Main funding by: National Institutes of Health