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Protein

Enhancer of mRNA-decapping protein 2

Gene

EDC2

Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

mRNA-binding protein which stimulates mRNA decapping by DCP1 and DCP2.3 Publications

Miscellaneous

Present with 538 molecules/cell in log phase SD medium.1 Publication

GO - Molecular functioni

  • mRNA binding Source: SGD

GO - Biological processi

Keywordsi

Molecular functionRNA-binding
Biological processmRNA processing, Nonsense-mediated mRNA decay

Enzyme and pathway databases

BioCyciYEAST:G3O-30216-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Enhancer of mRNA-decapping protein 2
Gene namesi
Name:EDC2
Ordered Locus Names:YER035W
OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Taxonomic identifieri559292 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
Proteomesi
  • UP000002311 Componenti: Chromosome V

Organism-specific databases

EuPathDBiFungiDB:YER035W
SGDiS000000837 EDC2

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Cytoplasm, Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002026261 – 145Enhancer of mRNA-decapping protein 2Add BLAST145

Proteomic databases

PaxDbiP40023

Interactioni

Binary interactionsi

Show more details

Protein-protein interaction databases

BioGridi36770, 61 interactors
DIPiDIP-5234N
IntActiP40023, 16 interactors
MINTiP40023
STRINGi4932.YER035W

Structurei

3D structure databases

ProteinModelPortaliP40023
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the EDC family.Curated

Phylogenomic databases

InParanoidiP40023
KOiK18759
OrthoDBiEOG092C5L2L

Sequencei

Sequence statusi: Complete.

P40023-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGSETKHSAK VKIVTRESPP SAKEHMRPTK TQILVPPTQS LPNGKKPNFG
60 70 80 90 100
KSTKQRREPR ERTSKTGHED DKATMVTVNI DAFLHDKAPK KKSCKYKKKK
110 120 130 140
TRQYQDRAAA SIDSKPHVAG HTAFAGASFT TDIPHEAALP KPSFV
Length:145
Mass (Da):16,071
Last modified:February 1, 1995 - v1
Checksum:i4D8A461EFD78BFA9
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U18796 Genomic DNA Translation: AAB64570.1
AY558451 Genomic DNA Translation: AAS56777.1
BK006939 Genomic DNA Translation: DAA07688.1
PIRiS50538
RefSeqiNP_010952.3, NM_001178926.3

Genome annotation databases

EnsemblFungiiYER035W; YER035W; YER035W
GeneIDi856757
KEGGisce:YER035W

Similar proteinsi

Entry informationi

Entry nameiEDC2_YEAST
AccessioniPrimary (citable) accession number: P40023
Secondary accession number(s): D3DLT4
Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 1, 1995
Last sequence update: February 1, 1995
Last modified: March 28, 2018
This is version 121 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome
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Main funding by: National Institutes of Health