P39991 (YEC5_YEAST) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Uncharacterized protein YEL025C

Gene names

Ordered Locus Names:

YEL025C

Organism

Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)

Taxonomic identifier

559292 [NCBI]

Taxonomic lineage

Eukaryota › Fungi › Dikarya › Ascomycota › Saccharomycotina › Saccharomycetes › Saccharomycetales › Saccharomycetaceae › Saccharomyces

Protein attributes

Sequence length	1188 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

General annotation (Comments)

Subcellular location

Membrane; Multi-pass membrane protein Potential.

Ontologies

Keywords
Cellular component	Membrane
Domain	Transmembrane Transmembrane helix
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Cellular component	cytoplasm Inferred from direct assay. Source: SGD integral to membrane Inferred from electronic annotation. Source: UniProtKB-KW nucleus Inferred from direct assay. Source: SGD
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 1188	1188	Uncharacterized protein YEL025C		PRO_0000202609
Regions
	Transmembrane	73 – 93	21	Helical; Potential
	Transmembrane	878 – 898	21	Helical; Potential
	Transmembrane	1089 – 1109	21	Helical; Potential

Sequences

	Sequence		Length	Mass (Da)
	P39991 [UniParc]. Last modified February 1, 1995. Version 1. Checksum: 82C3F04D1F78AD3D	FASTA	1,188	136,069
	10 20 30 40 50 60 MARQDETDCK KLDSNSAFLP LCITSYRSKD EAEKLVSCLH HEGSYFLCFS YGLYTGTSNE 70 80 90 100 110 120 LKAKVEFALD GPFVVNYATV PMFMSASFCH LLMFNDGSIK GFKCENNKFE IIYDSNVAPK 130 140 150 160 170 180 LDTISLLTSS WLNASFEGVL YTCNKNISYD SDLHTLCTTI YSFDFREGIV ERFYATDGEE 190 200 210 220 230 240 IISFDFISRE DLLDDATCTG KSHVYFLCLL KSCYSENLFL KEYNLAGKHG SRKFDLNEYR 250 260 270 280 290 300 QYNLLPICDN EFCYMKVVCG HTIVVLTTNY TQIINIKASG LTNGAFFNNK GLPNVENYQF 310 320 330 340 350 360 LKDSYDVIYE RSVILLTISD VYANKYTAKI HTRSLHRDHV LKELQWTKER VFKPPKHDLC 370 380 390 400 410 420 DVILQLPREK YIAVTRINGV NFISKDHRGS KLEKVKSGPA YTNKVYLASQ VIGNKGTDID 430 440 450 460 470 480 SLLLGGSFNS RRGFLEKKIL VYDKTLFKLV TSSKALVENV TDFWVTDLAL NGGDEFAYES 490 500 510 520 530 540 GGLIYKNGIF LMDEPYDYGL FVSRTGKVLK AGMDGSTGEF RQVDFLQSNH NSSTMFCYPV 550 560 570 580 590 600 QNSKLRISIL EAKSGFLRKK EEFFIHGLNS KESIVSCFSD GAEKYLFVIY LDGVFSVWNA 610 620 630 640 650 660 NQKKVATSHP DYSFIAYDQL IKISWLSKKH KHDSIYVIAS SYTGCVRVYK SESNFLRVDL 670 680 690 700 710 720 EIHSLYDQKL ELLDTIPSLP LVFLYNDKEI ILLNLQNMSY GCIQLGLVPR RMRIRPGKAL 730 740 750 760 770 780 FSLCVLDYDS RISIFEFGST FYREGFTKQM TSLKPQLENH IFYLPSIPVE LYTVPNNLNQ 790 800 810 820 830 840 AVVCLVDSNS RQYKLMLFNY ASMKAVSTFS FSDEKYLHAV VKPLWPEQNS IYLSQRPFYG 850 860 870 880 890 900 NKFVVCLGVG EKRTKFWLFE IRNNNITQLY ANYLEDCIFS VFIYYECNLV LFSGDSGIAA 910 920 930 940 950 960 YKINMLKEGA EILEAYSFPA LSSINHIGLP AYMSGDYLVQ FEILRDFLRT RFPIRTSIVY 970 980 990 1000 1010 1020 PSEYPECPYL GFKRLGSITQ VATKIIPKKL REPKNDCLAS DKNYLLGRLS DLSCATLKYS 1030 1040 1050 1060 1070 1080 NRSYVATIGI DNTLTIYEDS KLSVDKGGLA MPYLKIRLPN KIISLAAIPD GFQNLQICPN 1090 1100 1110 1120 1130 1140 FNSQRLEGVI PLFLLCGTEG QIYIISEFIG ELWMRTLHDY KKIKLECKRA FRRSEKSMRN 1150 1160 1170 1180 VTKQYSVSKE TGINESGFDE LARNSKRRHI DHSPYKTIDF FDPVKLKR

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"The nucleotide sequence of Saccharomyces cerevisiae chromosome V." Dietrich F.S., Mulligan J.T., Hennessy K.M., Yelton M.A., Allen E., Araujo R., Aviles E., Berno A., Brennan T., Carpenter J., Chen E., Cherry J.M., Chung E., Duncan M., Guzman E., Hartzell G., Hunicke-Smith S., Hyman R.W. , Kayser A., Komp C., Lashkari D., Lew H., Lin D., Mosedale D., Nakahara K., Namath A., Norgren R., Oefner P., Oh C., Petel F.X., Roberts D., Sehl P., Schramm S., Shogren T., Smith V., Taylor P., Wei Y., Botstein D., Davis R.W. Nature 387:78-81(1997) [PubMed: 9169868] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 204511 / S288c / AB972.
[2]	Saccharomyces Genome Database Submitted (DEC-2009) to the EMBL/GenBank/DDBJ databases Cited for: GENOME REANNOTATION. Strain: ATCC 204508 / S288c.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	U18530 Genomic DNA. Translation: AAB64502.1. BK006939 Genomic DNA. Translation: DAA07627.1.
PIR	S50434.
RefSeq	NP_010889.1. NM_001178840.1.
3D structure databases
ProteinModelPortal	P39991.
ModBase	Search...
Protein-protein interaction databases
MINT	MINT-2735254.
STRING	P39991.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblFungi	YEL025C; YEL025C; YEL025C.
GeneID	856688.
KEGG	sce:YEL025C.
NMPDR	fig|4932.3.peg.1943.
Organism-specific databases
CYGD	YEL025c.
SGD	S000000751. YEL025C.
Phylogenomic databases
OrthoDB	EOG437VQT.
Gene expression databases
ArrayExpress	P39991.
Genevestigator	P39991.
GermOnline	YEL025C. Saccharomyces cerevisiae.
Family and domain databases
InterPro	IPR015943. WD40/YVTN_repeat-like_dom. IPR011046. WD40_repeat-like_dom. [Graphical view]
Gene3D	G3DSA:2.130.10.10. WD40/YVTN_repeat-like. 1 hit.
SUPFAM	SSF50978. WD40_like. 1 hit.
ProtoNet	Search...
Other
NextBio	982727.

Entry information

Entry name

YEC5_YEAST

Accession

Primary (citable) accession number: P39991
Secondary accession number(s): D3DLM3

Entry history

Integrated into UniProtKB/Swiss-Prot:	February 1, 1995
Last sequence update:	February 1, 1995
Last modified:	December 14, 2011
This is version 64 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Fungal Protein Annotation Program