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Protein

Heat shock protein SSC3, mitochondrial

Gene

ECM10

Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Protein inferred from homologyi

Functioni

Plays a role in facilitating the assembly of some protein complexes inside the mitochondria. It may initiate the events that lead to refolding of imported precursors in the matrix space.1 Publication

GO - Molecular functioni

GO - Biological processi

  • protein refolding Source: SGD
  • protein targeting to mitochondrion Source: SGD

Keywordsi

Molecular functionChaperone
LigandATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciYEAST:G3O-30152-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Heat shock protein SSC3, mitochondrial
Alternative name(s):
Extracellular mutant protein 10
Gene namesi
Name:ECM10
Synonyms:SSC3
Ordered Locus Names:YEL030W
OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Taxonomic identifieri559292 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
Proteomesi
  • UP000002311 Componenti: Chromosome V

Organism-specific databases

EuPathDBiFungiDB:YEL030W.
SGDiS000000756. ECM10.

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Mitochondrion, Mitochondrion nucleoid

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_0000013554? – 644Heat shock protein SSC3, mitochondrial
Transit peptidei1 – ?MitochondrionSequence analysis

Proteomic databases

MaxQBiP39987.
PRIDEiP39987.

PTM databases

iPTMnetiP39987.

Interactioni

GO - Molecular functioni

Protein-protein interaction databases

BioGridi36699. 102 interactors.
DIPiDIP-6541N.
IntActiP39987. 19 interactors.
MINTiMINT-687991.
STRINGi4932.YEL030W.

Structurei

3D structure databases

ProteinModelPortaliP39987.
SMRiP39987.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the heat shock protein 70 family.Curated

Keywords - Domaini

Transit peptide

Phylogenomic databases

GeneTreeiENSGT00890000139503.
HOGENOMiHOG000228135.
InParanoidiP39987.
OMAiENTIYAT.
OrthoDBiEOG092C1VPN.

Family and domain databases

Gene3Di1.20.1270.10. 1 hit.
2.60.34.10. 1 hit.
HAMAPiMF_00332. DnaK. 1 hit.
InterProiView protein in InterPro
IPR012725. Chaperone_DnaK.
IPR018181. Heat_shock_70_CS.
IPR029048. HSP70_C_sf.
IPR029047. HSP70_peptide-bd_sf.
IPR013126. Hsp_70_fam.
PfamiView protein in Pfam
PF00012. HSP70. 1 hit.
PRINTSiPR00301. HEATSHOCK70.
SUPFAMiSSF100920. SSF100920. 1 hit.
SSF100934. SSF100934. 1 hit.
TIGRFAMsiTIGR02350. prok_dnaK. 1 hit.
PROSITEiView protein in PROSITE
PS00297. HSP70_1. 1 hit.
PS00329. HSP70_2. 1 hit.
PS01036. HSP70_3. 1 hit.

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

P39987-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLPSWKAFKA HNILRILTRF QSTKIPDAVI GIDLGTTNSA VAIMEGKVPR
60 70 80 90 100
IIENAEGSRT TPSVVAFTKD GERLVGEPAK RQSVINSENT LFATKRLIGR
110 120 130 140 150
RFEDAEVQRD INQVPFKIVK HSNGDAWVEA RNRTYSPAQI GGFILNKMKE
160 170 180 190 200
TAEAYLAKSV KNAVVTVPAY FNDAQRQATK DAGQIIGLNV LRVVNEPTAA
210 220 230 240 250
ALAYGLDKSE PKVIAVFDLG GGTFDISILD IDNGIFEVKS TNGDTHLGGE
260 270 280 290 300
DFDIYLLQEI ISHFKKETGI DLSNDRMAVQ RIREAAEKAK IELSSTLSTE
310 320 330 340 350
INLPFITADA AGPKHIRMPF SRVQLENITA PLIDRTVDPV KKALKDARIT
360 370 380 390 400
ASDISDVLLV GGMSRMPKVA DTVKKLFGKD ASKAVNPDEA VALGAAIQAA
410 420 430 440 450
VLSGEVTDVL LLDVTPLSLG IETLGGVFTK LIPRNSTIPN KKSQIFSTAA
460 470 480 490 500
SGQTSVEVKV FQGERELVKD NKLIGNFTLA GIPPAPKGTP QIEVTFDIDA
510 520 530 540 550
NGIINVSAKD LASHKDSSIT VAGASGLSDT EIDRMVNEAE RYKNQDRARR
560 570 580 590 600
NAIETANKAD QLANDTENSI KEFEGKLDKT DSQRLKDQIS SLRELVSRSQ
610 620 630 640
AGDEVNDDDV GTKIDNLRTS SMKLFEQLYK NSDNPETKNG RENK
Length:644
Mass (Da):70,084
Last modified:February 1, 1995 - v1
Checksum:i6A248DE208F513CB
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U18530 Genomic DNA. Translation: AAB64507.1.
BK006939 Genomic DNA. Translation: DAA07623.1.
PIRiS50429.
RefSeqiNP_010884.1. NM_001178845.1.

Genome annotation databases

EnsemblFungiiYEL030W; YEL030W; YEL030W.
GeneIDi856682.
KEGGisce:YEL030W.

Similar proteinsi

Entry informationi

Entry nameiHSP7E_YEAST
AccessioniPrimary (citable) accession number: P39987
Secondary accession number(s): D3DLL9
Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 1, 1995
Last sequence update: February 1, 1995
Last modified: November 22, 2017
This is version 149 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Yeast
    Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD
  3. Yeast chromosome V
    Yeast (Saccharomyces cerevisiae) chromosome V: entries and gene names