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Protein

Heat shock protein SSC3, mitochondrial

Gene

ECM10

Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Plays a role in facilitating the assembly of some protein complexes inside the mitochondria. It may initiate the events that lead to refolding of imported precursors in the matrix space.1 Publication

GO - Molecular functioni

GO - Biological processi

  • protein refolding Source: SGD
  • protein targeting to mitochondrion Source: SGD

Keywordsi

Molecular functionChaperone
LigandATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciYEAST:G3O-30152-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Heat shock protein SSC3, mitochondrial
Alternative name(s):
Extracellular mutant protein 10
Gene namesi
Name:ECM10
Synonyms:SSC3
Ordered Locus Names:YEL030W
OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Taxonomic identifieri559292 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
Proteomesi
  • UP000002311 Componenti: Chromosome V

Organism-specific databases

EuPathDBiFungiDB:YEL030W
SGDiS000000756 ECM10

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Mitochondrion, Mitochondrion nucleoid

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_0000013554? – 644Heat shock protein SSC3, mitochondrial
Transit peptidei1 – ?MitochondrionSequence analysis

Proteomic databases

MaxQBiP39987
PaxDbiP39987
PRIDEiP39987

PTM databases

iPTMnetiP39987

Interactioni

GO - Molecular functioni

Protein-protein interaction databases

BioGridi36699, 103 interactors
DIPiDIP-6541N
IntActiP39987, 19 interactors
MINTiP39987
STRINGi4932.YEL030W

Structurei

3D structure databases

ProteinModelPortaliP39987
SMRiP39987
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the heat shock protein 70 family.Curated

Keywords - Domaini

Transit peptide

Phylogenomic databases

GeneTreeiENSGT00920000150184
HOGENOMiHOG000228135
InParanoidiP39987
OMAiENTIYAT
OrthoDBiEOG092C1VPN

Family and domain databases

Gene3Di1.20.1270.10, 1 hit
2.60.34.10, 1 hit
HAMAPiMF_00332 DnaK, 1 hit
InterProiView protein in InterPro
IPR012725 Chaperone_DnaK
IPR018181 Heat_shock_70_CS
IPR029048 HSP70_C_sf
IPR029047 HSP70_peptide-bd_sf
IPR013126 Hsp_70_fam
PANTHERiPTHR19375 PTHR19375, 1 hit
PfamiView protein in Pfam
PF00012 HSP70, 1 hit
PRINTSiPR00301 HEATSHOCK70
SUPFAMiSSF100920 SSF100920, 1 hit
SSF100934 SSF100934, 1 hit
TIGRFAMsiTIGR02350 prok_dnaK, 1 hit
PROSITEiView protein in PROSITE
PS00297 HSP70_1, 1 hit
PS00329 HSP70_2, 1 hit
PS01036 HSP70_3, 1 hit

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

P39987-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLPSWKAFKA HNILRILTRF QSTKIPDAVI GIDLGTTNSA VAIMEGKVPR
60 70 80 90 100
IIENAEGSRT TPSVVAFTKD GERLVGEPAK RQSVINSENT LFATKRLIGR
110 120 130 140 150
RFEDAEVQRD INQVPFKIVK HSNGDAWVEA RNRTYSPAQI GGFILNKMKE
160 170 180 190 200
TAEAYLAKSV KNAVVTVPAY FNDAQRQATK DAGQIIGLNV LRVVNEPTAA
210 220 230 240 250
ALAYGLDKSE PKVIAVFDLG GGTFDISILD IDNGIFEVKS TNGDTHLGGE
260 270 280 290 300
DFDIYLLQEI ISHFKKETGI DLSNDRMAVQ RIREAAEKAK IELSSTLSTE
310 320 330 340 350
INLPFITADA AGPKHIRMPF SRVQLENITA PLIDRTVDPV KKALKDARIT
360 370 380 390 400
ASDISDVLLV GGMSRMPKVA DTVKKLFGKD ASKAVNPDEA VALGAAIQAA
410 420 430 440 450
VLSGEVTDVL LLDVTPLSLG IETLGGVFTK LIPRNSTIPN KKSQIFSTAA
460 470 480 490 500
SGQTSVEVKV FQGERELVKD NKLIGNFTLA GIPPAPKGTP QIEVTFDIDA
510 520 530 540 550
NGIINVSAKD LASHKDSSIT VAGASGLSDT EIDRMVNEAE RYKNQDRARR
560 570 580 590 600
NAIETANKAD QLANDTENSI KEFEGKLDKT DSQRLKDQIS SLRELVSRSQ
610 620 630 640
AGDEVNDDDV GTKIDNLRTS SMKLFEQLYK NSDNPETKNG RENK
Length:644
Mass (Da):70,084
Last modified:February 1, 1995 - v1
Checksum:i6A248DE208F513CB
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U18530 Genomic DNA Translation: AAB64507.1
BK006939 Genomic DNA Translation: DAA07623.1
PIRiS50429
RefSeqiNP_010884.1, NM_001178845.1

Genome annotation databases

EnsemblFungiiYEL030W; YEL030W; YEL030W
GeneIDi856682
KEGGisce:YEL030W

Similar proteinsi

Entry informationi

Entry nameiHSP7E_YEAST
AccessioniPrimary (citable) accession number: P39987
Secondary accession number(s): D3DLL9
Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 1, 1995
Last sequence update: February 1, 1995
Last modified: June 20, 2018
This is version 154 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

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