Reviewed,
UniProtKB/Swiss-Prot P39985 (DPO5_YEAST)
Last modified
December 15, 2009.
Version 78.
History...
Clusters with 100%,
90%,
50% identity |
Documents (3) |
Third-party data |
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Names and origin
| Protein names | Recommended name: DNA polymerase V Short name=POL V EC=2.7.7.7 | ||||
| Gene names |
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| Organism | Saccharomyces cerevisiae (Baker's yeast) [Complete proteome] | ||||
| Taxonomic identifier | 4932 [NCBI] | ||||
| Taxonomic lineage | Eukaryota › Fungi › Dikarya › Ascomycota › Saccharomycotina › Saccharomycetes › Saccharomycetales › Saccharomycetaceae › Saccharomyces |
Protein attributes
| Sequence length | 1022 AA. |
| Sequence status | Complete. |
| Sequence processing | The displayed sequence is not processed. |
| Protein existence | Evidence at protein level. |
General annotation (Comments)
| Function | Presumed to play a role other than chromosomal DNA replication. |
| Catalytic activity | Deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1). |
| Miscellaneous | Present with 4490 molecules/cell in log phase SD medium. Ref.4 |
| Sequence similarities | Belongs to the DNA polymerase type-B family. |
Ontologies
| Keywords | |
|---|---|
| Molecular function | DNA-directed DNA polymerase Nucleotidyltransferase Transferase |
| PTM | Phosphoprotein |
| Technical term | Complete proteome |
| Gene Ontology (GO) | |
| Biological process | rRNA transcription Ref.1 Inferred from mutant phenotype. Source: SGD |
| Cellular component | nucleolus Ref.1 Inferred from direct assay. Source: SGD |
| Molecular function | DNA binding Inferred from electronic annotation. Source: InterPro DNA-directed DNA polymerase activity Ref.1Inferred from direct assay. Source: SGD nucleotide bindingInferred from electronic annotation. Source: InterPro |
| Complete GO annotation... | |
Sequence annotation (Features)
Sequences
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References
| « Hide 'large scale' references | |
| [1] | "The fifth essential DNA polymerase phi in Saccharomyces cerevisiae is localized to the nucleolus and plays an important role in synthesis of rRNA." Shimizu K., Kawasaki Y., Hiraga S., Tawaramoto M., Nakashima N., Sugino A. Proc. Natl. Acad. Sci. U.S.A. 99:9133-9138(2002) [PubMed: 12093911] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA], VARIANT ASN-625. |
| [2] | "The nucleotide sequence of Saccharomyces cerevisiae chromosome V." Dietrich F.S., Mulligan J.T., Hennessy K.M., Yelton M.A., Allen E., Araujo R., Aviles E., Berno A., Brennan T., Carpenter J., Chen E., Cherry J.M., Chung E., Duncan M., Guzman E., Hartzell G., Hunicke-Smith S., Hyman R.W. Davis R.W.Nature 387:78-81(1997) [PubMed: 9169868] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 204511 / S288c / AB972. |
| [3] | "Yeast DNA polymerases and their role at the replication fork." Sugino A. Trends Biochem. Sci. 20:319-323(1995) [PubMed: 7667891] [Abstract] Cited for: IDENTIFICATION. |
| [4] | "Global analysis of protein expression in yeast." Ghaemmaghami S., Huh W.-K., Bower K., Howson R.W., Belle A., Dephoure N., O'Shea E.K., Weissman J.S. Nature 425:737-741(2003) [PubMed: 14562106] [Abstract] Cited for: LEVEL OF PROTEIN EXPRESSION [LARGE SCALE ANALYSIS]. |
| [5] | "A multidimensional chromatography technology for in-depth phosphoproteome analysis." Albuquerque C.P., Smolka M.B., Payne S.H., Bafna V., Eng J., Zhou H. Mol. Cell. Proteomics 7:1389-1396(2008) [PubMed: 18407956] [Abstract] Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT TYR-207, MASS SPECTROMETRY. |
| + | Additional computationally mapped references. |
Cross-references
Sequence databases | |
|---|---|
| AB027253 Genomic DNA. Translation: BAA77722.1. U18795 Genomic DNA. Translation: AAB65032.1. | |
| PIR | S50534. |
| RefSeq | NP_010859.1. |
3D structure databases | |
| ModBase | Search... |
Protein-protein interaction databases | |
| DIP | DIP-6314N. |
| IntAct | P39985. 14 interactions. |
| STRING | P39985. |
Proteomic databases | |
| PeptideAtlas | P39985. |
| PRIDE | P39985. |
Genome annotation databases | |
| Ensembl | YEL055C; YEL055C; YEL055C; Saccharomyces cerevisiae. [Genome view] |
| GeneID | 856655. |
| KEGG | sce:YEL055C. |
| NMPDR | fig|4932.3.peg.1908. |
Organism-specific databases | |
| CYGD | YEL055c. |
| SGD | S000000781. POL5. |
Phylogenomic databases | |
| HOGENOM | HBG397536. |
| OMA | SERKYLG. |
| OrthoDB | EOG96MD2D. |
Enzyme and pathway databases | |
| BRENDA | 2.7.7.7. 250. |
Gene expression databases | |
| ArrayExpress | P39985. |
| Genevestigator | P39985. |
| GermOnline | YEL055C. Saccharomyces cerevisiae. |
Family and domain databases | |
| InterPro | IPR017964. DNA-dir_DNA_pol_B_CS. IPR007015. DNA_pol_V. [Graphical view] |
| PANTHER | PTHR13213. DNA_pol_V. 1 hit. |
| Pfam | PF04931. DNA_pol_phi. 1 hit. [Graphical view] |
| PROSITE | PS00116. DNA_POLYMERASE_B. 1 hit. [Graphical view] |
| ProtoNet | Search... |
Other Resources | |
| NextBio | 982640. |
Entry information
| Entry name | DPO5_YEAST | ||||||||
| Accession | Primary (citable) accession number: P39985 Secondary accession number(s): Q9Y737 | ||||||||
| Entry history |
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| Entry status | Reviewed (UniProtKB/Swiss-Prot) | ||||||||
| Annotation project | FPAP (Fungal Proteome Annotation Project) | ||||||||
Relevant documents
| SIMILARITY comments Index of protein domains and families |
| Yeast Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD |
| Yeast chromosome V Yeast (Saccharomyces cerevisiae) chromosome V: entries and gene names |

Clusters with


