P39985 (DPO5_YEAST) Reviewed, UniProtKB/Swiss-Prot
Last modified
December 14, 2011.
Version 95.
History...
Names·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order
Names·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize orderNames and origin
| Protein names | Recommended name: DNA polymerase V Short name=POL V EC=2.7.7.7 | ||||
| Gene names |
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| Organism | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) | ||||
| Taxonomic identifier | 559292 [NCBI] | ||||
| Taxonomic lineage | Eukaryota › Fungi › Dikarya › Ascomycota › Saccharomycotina › Saccharomycetes › Saccharomycetales › Saccharomycetaceae › Saccharomyces |
Protein attributes
| Sequence length | 1022 AA. |
| Sequence status | Complete. |
| Protein existence | Evidence at protein level |
General annotation (Comments)
| Function | Presumed to play a role other than chromosomal DNA replication. |
| Catalytic activity | Deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1). |
| Subunit structure | Interacts with FRK1. Ref.7 |
| Miscellaneous | Present with 4490 molecules/cell in log phase SD medium. Ref.5 |
| Sequence similarities | Belongs to the DNA polymerase type-B family. |
Ontologies
| Keywords | |
|---|---|
| Molecular function | DNA-directed DNA polymerase Nucleotidyltransferase Transferase |
| PTM | Phosphoprotein |
| Technical term | Complete proteome Reference proteome |
| Gene Ontology (GO) | |
| Biological process | rRNA transcription Inferred from mutant phenotype Ref.1. Source: SGD |
| Cellular component | nucleolus Inferred from direct assay Ref.1. Source: SGD |
| Molecular function | DNA binding Inferred from electronic annotation. Source: InterPro DNA-directed DNA polymerase activityInferred from direct assay Ref.1. Source: SGD nucleotide bindingInferred from electronic annotation. Source: InterPro |
| Complete GO annotation... | |
Sequence annotation (Features)
Sequences
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References
| « Hide 'large scale' references | |
| [1] | "The fifth essential DNA polymerase phi in Saccharomyces cerevisiae is localized to the nucleolus and plays an important role in synthesis of rRNA." Shimizu K., Kawasaki Y., Hiraga S., Tawaramoto M., Nakashima N., Sugino A. Proc. Natl. Acad. Sci. U.S.A. 99:9133-9138(2002) [PubMed: 12093911] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA], VARIANT ASN-625. |
| [2] | "The nucleotide sequence of Saccharomyces cerevisiae chromosome V." Dietrich F.S., Mulligan J.T., Hennessy K.M., Yelton M.A., Allen E., Araujo R., Aviles E., Berno A., Brennan T., Carpenter J., Chen E., Cherry J.M., Chung E., Duncan M., Guzman E., Hartzell G., Hunicke-Smith S., Hyman R.W. Davis R.W.Nature 387:78-81(1997) [PubMed: 9169868] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 204511 / S288c / AB972. |
| [3] | Saccharomyces Genome Database Submitted (DEC-2009) to the EMBL/GenBank/DDBJ databases Cited for: GENOME REANNOTATION. Strain: ATCC 204508 / S288c. |
| [4] | "Yeast DNA polymerases and their role at the replication fork." Sugino A. Trends Biochem. Sci. 20:319-323(1995) [PubMed: 7667891] [Abstract] Cited for: IDENTIFICATION. |
| [5] | "Global analysis of protein expression in yeast." Ghaemmaghami S., Huh W.-K., Bower K., Howson R.W., Belle A., Dephoure N., O'Shea E.K., Weissman J.S. Nature 425:737-741(2003) [PubMed: 14562106] [Abstract] Cited for: LEVEL OF PROTEIN EXPRESSION [LARGE SCALE ANALYSIS]. |
| [6] | "A multidimensional chromatography technology for in-depth phosphoproteome analysis." Albuquerque C.P., Smolka M.B., Payne S.H., Bafna V., Eng J., Zhou H. Mol. Cell. Proteomics 7:1389-1396(2008) [PubMed: 18407956] [Abstract] Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT TYR-207, MASS SPECTROMETRY. |
| [7] | "A global protein kinase and phosphatase interaction network in yeast." Breitkreutz A., Choi H., Sharom J.R., Boucher L., Neduva V., Larsen B., Lin Z.Y., Breitkreutz B.J., Stark C., Liu G., Ahn J., Dewar-Darch D., Reguly T., Tang X., Almeida R., Qin Z.S., Pawson T., Gingras A.C., Nesvizhskii A.I., Tyers M. Science 328:1043-1046(2010) [PubMed: 20489023] [Abstract] Cited for: IDENTIFICATION BY MASS SPECTROMETRY, INTERACTION WITH FRK1. |
| + | Additional computationally mapped references. |
Cross-references
Sequence databases | |
|---|---|
| EMBL GenBank DDBJ | AB027253 Genomic DNA. Translation: BAA77722.1. U18795 Genomic DNA. Translation: AAB65032.1. BK006939 Genomic DNA. Translation: DAA07599.1. |
| PIR | S50534. |
| RefSeq | NP_010859.1. NM_001178870.1. |
3D structure databases | |
| ProteinModelPortal | P39985. |
| ModBase | Search... |
Protein-protein interaction databases | |
| DIP | DIP-6314N. |
| IntAct | P39985. 17 interactions. |
| MINT | MINT-650861. |
| STRING | P39985. |
Proteomic databases | |
| PeptideAtlas | P39985. |
Protocols and materials databases | |
| StructuralBiologyKnowledgebase | Search... |
Genome annotation databases | |
| EnsemblFungi | YEL055C; YEL055C; YEL055C. |
| GeneID | 856655. |
| KEGG | sce:YEL055C. |
| NMPDR | fig|4932.3.peg.1908. |
Organism-specific databases | |
| CYGD | YEL055c. |
| SGD | S000000781. POL5. |
Phylogenomic databases | |
| eggNOG | fuNOG07725. |
| GeneTree | EFGT00050000002593. |
| HOGENOM | HBG397536. |
| OMA | ERKYWGF. |
| OrthoDB | EOG4MPMZK. |
Gene expression databases | |
| ArrayExpress | P39985. |
| Genevestigator | P39985. |
| GermOnline | YEL055C. Saccharomyces cerevisiae. |
Family and domain databases | |
| InterPro | IPR016024. ARM-type_fold. IPR017964. DNA-dir_DNA_pol_B_CS. IPR007015. DNA_pol_V. [Graphical view] |
| KO | K02331. |
| PANTHER | PTHR13213. DNA_pol_V. 1 hit. |
| Pfam | PF04931. DNA_pol_phi. 1 hit. [Graphical view] |
| SUPFAM | SSF48371. ARM-type_fold. 1 hit. |
| PROSITE | PS00116. DNA_POLYMERASE_B. 1 hit. [Graphical view] |
| ProtoNet | Search... |
Other | |
| NextBio | 982640. |
Entry information
| Entry name | DPO5_YEAST | ||||||||
| Accession | Primary (citable) accession number: P39985 Secondary accession number(s): D3DLJ5, Q9Y737 | ||||||||
| Entry history |
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| Entry status | Reviewed (UniProtKB/Swiss-Prot) | ||||||||
| Annotation program | Fungal Protein Annotation Program | ||||||||
Relevant documents
| Yeast Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD |
| Yeast chromosome V Yeast (Saccharomyces cerevisiae) chromosome V: entries and gene names |
| SIMILARITY comments Index of protein domains and families |

Clusters with