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Protein

Protein BOI2

Gene

BOI2

Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Binds to the BEM1 protein. Involved in bud formation.

Miscellaneous

Present with 688 molecules/cell in log phase SD medium.1 Publication

GO - Molecular functioni

  • phospholipid binding Source: SGD

GO - Biological processi

  • budding cell apical bud growth Source: SGD
  • cell separation after cytokinesis Source: SGD
  • establishment of cell polarity Source: SGD
  • Rho protein signal transduction Source: SGD

Enzyme and pathway databases

BioCyciYEAST:G3O-30278-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Protein BOI2
Alternative name(s):
Protein BEB1
Gene namesi
Name:BOI2
Synonyms:BEB1
Ordered Locus Names:YER114C
OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Taxonomic identifieri559292 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
Proteomesi
  • UP000002311 Componenti: Chromosome V

Organism-specific databases

EuPathDBiFungiDB:YER114C
SGDiS000000916 BOI2

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Cytoplasm, Cytoskeleton

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000649701 – 1040Protein BOI2Add BLAST1040

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei18PhosphoserineCombined sources1
Modified residuei24PhosphoserineCombined sources1
Modified residuei28PhosphoserineCombined sources1
Modified residuei450PhosphoserineCombined sources1
Modified residuei519PhosphoserineCombined sources1
Modified residuei523PhosphoserineCombined sources1
Modified residuei546PhosphoserineCombined sources1
Modified residuei652PhosphoserineCombined sources1

Keywords - PTMi

Phosphoprotein

Proteomic databases

MaxQBiP39969
PaxDbiP39969
PRIDEiP39969

PTM databases

CarbonylDBiP39969
iPTMnetiP39969

Interactioni

Binary interactionsi

Show more details

Protein-protein interaction databases

BioGridi36859, 102 interactors
DIPiDIP-2227N
IntActiP39969, 34 interactors
MINTiP39969
STRINGi4932.YER114C

Structurei

3D structure databases

ProteinModelPortaliP39969
SMRiP39969
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini43 – 107SH3PROSITE-ProRule annotationAdd BLAST65
Domaini266 – 330SAMPROSITE-ProRule annotationAdd BLAST65
Domaini768 – 887PHPROSITE-ProRule annotationAdd BLAST120

Keywords - Domaini

SH3 domain

Phylogenomic databases

GeneTreeiENSGT00530000066577
HOGENOMiHOG000066063
InParanoidiP39969
OMAiMDQSSLF
OrthoDBiEOG092C356K

Family and domain databases

CDDicd11886 SH3_BOI, 1 hit
Gene3Di2.30.29.30, 1 hit
InterProiView protein in InterPro
IPR035551 Boi1/2_SH3
IPR011993 PH-like_dom_sf
IPR001849 PH_domain
IPR001660 SAM
IPR013761 SAM/pointed_sf
IPR036028 SH3-like_dom_sf
IPR001452 SH3_domain
PfamiView protein in Pfam
PF00169 PH, 1 hit
PF07647 SAM_2, 1 hit
PF00018 SH3_1, 1 hit
SMARTiView protein in SMART
SM00233 PH, 1 hit
SM00454 SAM, 1 hit
SM00326 SH3, 1 hit
SUPFAMiSSF47769 SSF47769, 1 hit
SSF50044 SSF50044, 1 hit
PROSITEiView protein in PROSITE
PS50003 PH_DOMAIN, 1 hit
PS50105 SAM_DOMAIN, 1 hit
PS50002 SH3, 1 hit

Sequencei

Sequence statusi: Complete.

P39969-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSNDREVPTL SQLNTTVSRD KDVSDTLSPD FDSKGSATGR DGGNFPMYIA
60 70 80 90 100
INEYFKRMED ELDMKPGDKI KVITDDEEYK DGWYFGRNLR TNEEGLYPVV
110 120 130 140 150
FTQKITVEKA PTLMRAKSTK RIYSPLTNED PLLSSTFISE NDSNSELPTP
160 170 180 190 200
QPIETAASIS RTANGKIERN LSLKNTMSDI DNALLEFKDD SIGPPDRFIN
210 220 230 240 250
SGRDEEHSIT HETILSATDG LDVVESNSKP TTSSSTGFLN GDLENQATLI
260 270 280 290 300
NGIDTTKLNP VEAEFWSPEE ITAYFIMEGY DVQSASRFQK HKISGKILLE
310 320 330 340 350
LELVHLKELD INSFGTRFEI FKEIEKIKEA IRTNGRSLNR ASKTNNANIY
360 370 380 390 400
NQLMPPANVD QRASYRGHVR KTSQSLEDLP SQQNFIPTPR NTRNSSASKH
410 420 430 440 450
RPKSLVFDSQ EANANIAPDV QIPQVVEEMA GNENLFVSPR RAPKPPSYPS
460 470 480 490 500
PAQPPKSPLL NNTRTSPSPA QLYSWQSPTL SFSGPKRTSY IDQYSSSDSN
510 520 530 540 550
FNSRSALPKN NQGGGKALSP IPSPTRNSVR NEDSEGKLTS SSKRNSVPYY
560 570 580 590 600
GYAPESSSDR KSSCSSHEEE QFQETMNTFE RPTSSIYADG STIASISNDK
610 620 630 640 650
LAHEKEGKKK PTRHSSSLSS KSKSDSRRNS SLKRSSSASR TSSFKKSSFM
660 670 680 690 700
LSPFRQQFTD NAARSSSPEE NPITSMPSEK NSSPIVDKKS SKKSRSKRRS
710 720 730 740 750
VSAKEAEIFT ETVKDDKNKR SASEAIKGET LKGKSLRQMT ARPVAKKKQT
760 770 780 790 800
SAFIEGLRSI SVKEAMKDAD FSGWMSKKGS GAMSTWKTRF FTLHGTRLSY
810 820 830 840 850
FSSTTDTRER GLIDITAHRV VPAKEDDKLV SLYAASTGKG RYCFKLLPPQ
860 870 880 890 900
PGSKKGLTFT QPRTHYFAVD NKEEMRGWMA ALIKTTIDID TSVPIISSYT
910 920 930 940 950
TPTVSLSKAQ EMLAEAREET KLREQQMLEN EEDEDQFLWD QQQLQQQQHD
960 970 980 990 1000
NNQGQADRTI SASTQRTSDE DNTISTPNLS SANNTTIGSN GFSSPFLLAS
1010 1020 1030 1040
GLLSPGVARN SSMRGTEKKG KFSTEEDYFG DNSKHKTDKI
Length:1,040
Mass (Da):115,688
Last modified:February 1, 1995 - v1
Checksum:i2DC635B1A34E7479
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti733G → A in BAA07427 (PubMed:8666671).Curated1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
D38310 Genomic DNA Translation: BAA07427.1
U18916 Genomic DNA Translation: AAC03212.1
BK006939 Genomic DNA Translation: DAA07774.1
PIRiS50617
RefSeqiNP_011039.1, NM_001179004.1

Genome annotation databases

EnsemblFungiiYER114C; YER114C; YER114C
GeneIDi856850
KEGGisce:YER114C

Similar proteinsi

Entry informationi

Entry nameiBOI2_YEAST
AccessioniPrimary (citable) accession number: P39969
Secondary accession number(s): D3DM20
Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 1, 1995
Last sequence update: February 1, 1995
Last modified: May 23, 2018
This is version 169 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Yeast
    Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD
  2. Yeast chromosome V
    Yeast (Saccharomyces cerevisiae) chromosome V: entries and gene names

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