SAP1

Functionⁱ

Miscellaneous

Present with 300 molecules/cell in log phase SD medium.1 Publication

Regions

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Nucleotide bindingⁱ	645 – 652	ATPSequence analysis		8

GO - Molecular functionⁱ

ATPase activity
Source: SGD
Inferred from sequence or structural similarityⁱ
- 8654588
ATP binding Source: UniProtKB-KW

Complete GO annotation...

Keywordsⁱ

Ligand	ATP-binding, Nucleotide-binding

Ligand

ATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCycⁱ	YEAST:G3O-30226-MONOMER.

BioCycⁱ

YEAST:G3O-30226-MONOMER.

Names & Taxonomyⁱ

Protein namesⁱ	Recommended name: Protein SAP1 Alternative name(s): SIN1-associated protein
Gene namesⁱ	Name:SAP1 Ordered Locus Names:YER047C
Organismⁱ	Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Taxonomic identifierⁱ	559292 [NCBI]
Taxonomic lineageⁱ	cellular organisms › Eukaryota › Opisthokonta › Fungi › Dikarya › Ascomycota › saccharomyceta › Saccharomycotina › Saccharomycetes › Saccharomycetales › Saccharomycetaceae › Saccharomyces › Saccharomyces cerevisiae
Proteomesⁱ	UP000002311 Componentⁱ: Chromosome V

Organism-specific databases

EuPathDBⁱ	FungiDB:YER047C.
Saccharomyces Genome Database More...SGDⁱ	S000000849. SAP1.

Subcellular locationⁱ

GO - Cellular componentⁱ

nucleus Source: GO_Central

Complete GO annotation...

PTM / Processingⁱ

Molecule processing

Feature key	Position(s)	DescriptionActions	Graphical view	Length
ChainⁱPRO_0000084761	1 – 897	Protein SAP1Add BLAST		897

Amino acid modifications

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Modified residueⁱ	536	PhosphoserineCombined sources		1

Keywords - PTMⁱ

Phosphoprotein

Proteomic databases

MaxQB - The MaxQuant DataBase More...MaxQBⁱ	P39955.
PRIDEⁱ	P39955.
TopDownProteomicsⁱ	P39955.

PTM databases

iPTMnetⁱ	P39955.

iPTMnetⁱ

P39955.

Interactionⁱ

Subunit structureⁱ

Interacts with SPT2/SIN1.

Binary interactionsⁱ

With	Entry	#Exp.	IntAct
HOF1	Q05080	4	EBI-16463,EBI-5412
MYO3	P36006	3	EBI-16463,EBI-11670
MYO5	Q04439	4	EBI-16463,EBI-11687

Show more details

Protein-protein interaction databases

BioGridⁱ	36784. 83 interactors.
Database of interacting proteins More...DIPⁱ	DIP-1550N.
IntActⁱ	P39955. 16 interactors.
Molecular INTeraction database More...MINTⁱ	MINT-407680.
STRINGⁱ	4932.YER047C.

Structureⁱ

3D structure databases

ProteinModelPortalⁱ	P39955.
SMRⁱ	P39955.
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Family & Domainsⁱ

Sequence similaritiesⁱ

Belongs to the AAA ATPase family.Curated

Phylogenomic databases

Ensembl GeneTree More...GeneTreeⁱ	ENSGT00570000078874.
HOGENOMⁱ	HOG000216613.
InParanoidⁱ	P39955.
OMAⁱ	ANETIYY.
Database of Orthologous Groups More...OrthoDBⁱ	EOG092C2QJ3.

Family and domain databases

InterProⁱ	View protein in InterPro IPR003593. AAA+_ATPase. IPR003959. ATPase_AAA_core. IPR003960. ATPase_AAA_CS. IPR027417. P-loop_NTPase. IPR015415. Vps4_C.
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF00004. AAA. 1 hit. PF09336. Vps4_C. 1 hit.
SMARTⁱ	View protein in SMART SM00382. AAA. 1 hit.
SUPFAMⁱ	SSF52540. SSF52540. 1 hit.
PROSITEⁱ	View protein in PROSITE PS00674. AAA. 1 hit.

Sequenceⁱ

Sequence statusⁱ: Complete.

P39955-1 [UniParc]FASTA Add to basket

« Hide

        10         20         30         40         50
MDSQRSHHIL TRLTKIRRRP QQPLTDFTEL YSRIANETIY YLNLEEKKRY 
        60         70         80         90        100
KEALQGWKAL TTDVLFKQTL IEHNYPNTQS YTKDEVSLQN GIRELYHKSV 
       110        120        130        140        150
MHLKRVKKLV REEPAPRNDM PSSKTYTNHS SSFTRSTEPP PVFQMVPGRM 
       160        170        180        190        200
MKTLRNRNAC GYKTAYSNPS LSSYGNSTSI KRGEDAENIR VNFVPSKPLS 
       210        220        230        240        250
NNASRQHKNP IEHNDPPLKK ETELYSDKYI SEPILIDLTN DEDDHDVGIL 
       260        270        280        290        300
KGHNVFDEEE SDGFEFDVSD YYDNFSEVDV EEEEEEKEER RRIKTLEAIQ 
       310        320        330        340        350
QQMSDLSVTS STSSNKSVSS SENVPGSCIQ SLPTTAPALP SLPPPPLLNV 
       360        370        380        390        400
DRASSTGALK PHSLETSTTM DSSKIRNPQI SKLMKNNHVP YLKGTKSTPT 
       410        420        430        440        450
LITKSTPTFI TRSKSNTKPI IKSNASSPTS SLTVPNSVIQ KPKTAAMAAK 
       460        470        480        490        500
RVLNSKKVAS NPALNTTKKS HPILKSKTAK VPNSSSKKTS SHPSRPVSNS 
       510        520        530        540        550
KPYSHGASQN KKPSKNQTTS MSKTNRKIPA QKKIGSPKIE DVGTEDATEH 
       560        570        580        590        600
ATSLNEQREE PEIDKKVLRE ILEDEIIDSL QGVDRQAAKQ IFAEIVVHGD 
       610        620        630        640        650
EVHWDDIAGL ESAKYSLKEA VVYPFLRPDL FRGLREPVRG MLLFGPPGTG 
       660        670        680        690        700
KTMLARAVAT ESHSTFFSIS ASSLTSKYLG ESEKLVRALF AIAKKLSPSI 
       710        720        730        740        750
IFVDEIDSIM GSRNNENENE SSRRIKNEFL VQWSSLSSAA AGSNKSNTNN 
       760        770        780        790        800
SDTNGDEDDT RVLVLAATNL PWSIDEAARR RFVRRQYIPL PEDQTRHVQF 
       810        820        830        840        850
KKLLSHQKHT LTESDFDELV KITEGYSGSD ITSLAKDAAM GPLRDLGDKL 
       860        870        880        890 
LETEREMIRP IGLVDFKNSL VYIKPSVSQD GLVKYEKWAS QFGSSGS

Length:897

Mass (Da):100,332

Last modified:February 1, 1995 - v1

Checksum:ⁱE9780B269700144C

GO

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	U18796 Genomic DNA. Translation: AAB64582.1. BK006939 Genomic DNA. Translation: DAA07702.1.
PIRⁱ	S50550.
NCBI Reference Sequences More...RefSeqⁱ	NP_010966.1. NM_001178938.1.

Genome annotation databases

EnsemblFungiⁱ	YER047C; YER047C; YER047C.
GeneIDⁱ	856771.
KEGGⁱ	sce:YER047C.

Similar proteinsⁱ

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:

100%	UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%	UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%	UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.

Cross-referencesⁱ

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	U18796 Genomic DNA. Translation: AAB64582.1. BK006939 Genomic DNA. Translation: DAA07702.1.
PIRⁱ	S50550.
NCBI Reference Sequences More...RefSeqⁱ	NP_010966.1. NM_001178938.1.

3D structure databases

ProteinModelPortalⁱ	P39955.
SMRⁱ	P39955.
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Protein-protein interaction databases

BioGridⁱ	36784. 83 interactors.
Database of interacting proteins More...DIPⁱ	DIP-1550N.
IntActⁱ	P39955. 16 interactors.
Molecular INTeraction database More...MINTⁱ	MINT-407680.
STRINGⁱ	4932.YER047C.

PTM databases

iPTMnetⁱ	P39955.

iPTMnetⁱ

P39955.

Proteomic databases

MaxQB - The MaxQuant DataBase More...MaxQBⁱ	P39955.
PRIDEⁱ	P39955.
TopDownProteomicsⁱ	P39955.

Protocols and materials databases

Structural Biology Knowledgebase	Search...

Structural Biology Knowledgebase

Search...

Genome annotation databases

EnsemblFungiⁱ	YER047C; YER047C; YER047C.
GeneIDⁱ	856771.
KEGGⁱ	sce:YER047C.

Organism-specific databases

EuPathDBⁱ	FungiDB:YER047C.
Saccharomyces Genome Database More...SGDⁱ	S000000849. SAP1.

Phylogenomic databases

Ensembl GeneTree More...GeneTreeⁱ	ENSGT00570000078874.
HOGENOMⁱ	HOG000216613.
InParanoidⁱ	P39955.
OMAⁱ	ANETIYY.
Database of Orthologous Groups More...OrthoDBⁱ	EOG092C2QJ3.

Enzyme and pathway databases

BioCycⁱ	YEAST:G3O-30226-MONOMER.

BioCycⁱ

YEAST:G3O-30226-MONOMER.

Miscellaneous databases

Protein Ontology More...PROⁱ	PR:P39955.

PROⁱ

PR:P39955.

Family and domain databases

InterProⁱ	View protein in InterPro IPR003593. AAA+_ATPase. IPR003959. ATPase_AAA_core. IPR003960. ATPase_AAA_CS. IPR027417. P-loop_NTPase. IPR015415. Vps4_C.
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF00004. AAA. 1 hit. PF09336. Vps4_C. 1 hit.
SMARTⁱ	View protein in SMART SM00382. AAA. 1 hit.
SUPFAMⁱ	SSF52540. SSF52540. 1 hit.
PROSITEⁱ	View protein in PROSITE PS00674. AAA. 1 hit.
ProtoNetⁱ	Search...

Entry informationⁱ

Entry nameⁱ	SAP1_YEAST
Accessionⁱ	P39955Primary (citable) accession number: P39955 Secondary accession number(s): D3DLU8
Entry historyⁱ	Integrated into UniProtKB/Swiss-Prot:	February 1, 1995
	Last sequence update:	February 1, 1995
	Last modified:	July 5, 2017
	This is version 129 of the entry and version 1 of the sequence. See complete history.
Entry statusⁱ	Reviewed (UniProtKB/Swiss-Prot)
Annotation program	Fungal Protein Annotation Program

Miscellaneousⁱ

Keywords - Technical termⁱ

Complete proteome, Reference proteome

Documents

SIMILARITY comments
Index of protein domains and families
Yeast
Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD
Yeast chromosome V
Yeast (Saccharomyces cerevisiae) chromosome V: entries and gene names

UniProtKB

UniParc

Help

UniRef

Proteomes

Annotation systems

Supporting data

UniProtKB - P39955 (SAP1_YEAST)

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Protein SAP1

Select a section on the left to see content.

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Miscellaneous

Regions

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

Enzyme and pathway databases

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

Organism-specific databases

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Cellular componenti

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Amino acid modifications

Proteomic databases

PTM databases

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Phylogenomic databases

Family and domain databases

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including length and molecular weight.<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

Sequence databases

Genome annotation databases

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

3D structure databases

Protein-protein interaction databases

PTM databases

Proteomic databases

Protocols and materials databases

Genome annotation databases

Organism-specific databases

Phylogenomic databases

Enzyme and pathway databases

Miscellaneous databases

Family and domain databases

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Documents

Functionⁱ

GO - Molecular functionⁱ

Names & Taxonomyⁱ

Subcellular locationⁱ

GO - Cellular componentⁱ

PTM / Processingⁱ

Interactionⁱ

Structureⁱ

Family & Domainsⁱ

Sequence similaritiesⁱ

Sequenceⁱ

Cross-referencesⁱ

Entry informationⁱ

Miscellaneousⁱ