Protein SAP1

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functionⁱ

Miscellaneous

Regions

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functionⁱ

• ATPase activity Source: SGD <p>Inferred from Sequence or Structural Similarity<br />Used for any analysis based on sequence alignment, structure comparison, or evaluation of sequence features such as composition.</p> <p>More information in the <a href="http://geneontology.org/page/guide-go-evidence-codes#iss">GO evidence code guide</a></p> Inferred from sequence or structural similarityⁱ
  • 8654588
• ATP binding Source: UniProtKB-KW
• microtubule-severing ATPase activity Source: GO_Central

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Biological processⁱ

• cytoplasmic microtubule organization Source: GO_Central

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsⁱ

Enzyme and pathway databases

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyⁱ

Organism-specific databases

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationⁱ

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Cellular componentⁱ

• nucleus Source: GO_Central

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingⁱ

Molecule processing

Amino acid modifications

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - PTMⁱ

Proteomic databases

PTM databases

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactionⁱ

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction_section">‘Interaction’</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function_section">‘Function’</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structureⁱ

<p>This subsection of the ‘Interaction’ section provides information about binary protein-protein interactions. The data presented in this section are a quality-filtered subset of binary interactions automatically derived from the <a href="http://www.ebi.ac.uk/intact/">IntAct database</a>. It is updated on a monthly basis. Each binary interaction is displayed on a separate line.<p><a href='/help/binary_interactions' target='_top'>More...</a></p>Binary interactionsⁱ

Protein-protein interaction databases

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structureⁱ

3D structure databases

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsⁱ

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesⁱ

Phylogenomic databases

Family and domain databases

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including length and molecular weight.<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequenceⁱ

<p>This subsection of the ‘Sequence’ section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusⁱ: Complete.

        10         20         30         40         50
MDSQRSHHIL TRLTKIRRRP QQPLTDFTEL YSRIANETIY YLNLEEKKRY 
        60         70         80         90        100
KEALQGWKAL TTDVLFKQTL IEHNYPNTQS YTKDEVSLQN GIRELYHKSV 
       110        120        130        140        150
MHLKRVKKLV REEPAPRNDM PSSKTYTNHS SSFTRSTEPP PVFQMVPGRM 
       160        170        180        190        200
MKTLRNRNAC GYKTAYSNPS LSSYGNSTSI KRGEDAENIR VNFVPSKPLS 
       210        220        230        240        250
NNASRQHKNP IEHNDPPLKK ETELYSDKYI SEPILIDLTN DEDDHDVGIL 
       260        270        280        290        300
KGHNVFDEEE SDGFEFDVSD YYDNFSEVDV EEEEEEKEER RRIKTLEAIQ 
       310        320        330        340        350
QQMSDLSVTS STSSNKSVSS SENVPGSCIQ SLPTTAPALP SLPPPPLLNV 
       360        370        380        390        400
DRASSTGALK PHSLETSTTM DSSKIRNPQI SKLMKNNHVP YLKGTKSTPT 
       410        420        430        440        450
LITKSTPTFI TRSKSNTKPI IKSNASSPTS SLTVPNSVIQ KPKTAAMAAK 
       460        470        480        490        500
RVLNSKKVAS NPALNTTKKS HPILKSKTAK VPNSSSKKTS SHPSRPVSNS 
       510        520        530        540        550
KPYSHGASQN KKPSKNQTTS MSKTNRKIPA QKKIGSPKIE DVGTEDATEH 
       560        570        580        590        600
ATSLNEQREE PEIDKKVLRE ILEDEIIDSL QGVDRQAAKQ IFAEIVVHGD 
       610        620        630        640        650
EVHWDDIAGL ESAKYSLKEA VVYPFLRPDL FRGLREPVRG MLLFGPPGTG 
       660        670        680        690        700
KTMLARAVAT ESHSTFFSIS ASSLTSKYLG ESEKLVRALF AIAKKLSPSI 
       710        720        730        740        750
IFVDEIDSIM GSRNNENENE SSRRIKNEFL VQWSSLSSAA AGSNKSNTNN 
       760        770        780        790        800
SDTNGDEDDT RVLVLAATNL PWSIDEAARR RFVRRQYIPL PEDQTRHVQF 
       810        820        830        840        850
KKLLSHQKHT LTESDFDELV KITEGYSGSD ITSLAKDAAM GPLRDLGDKL 
       860        870        880        890 
LETEREMIRP IGLVDFKNSL VYIKPSVSQD GLVKYEKWAS QFGSSGS 

Sequence databases

Genome annotation databases

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesⁱ

Sequence databases

3D structure databases

Protein-protein interaction databases

PTM databases

Proteomic databases

Protocols and materials databases

Genome annotation databases

Organism-specific databases

Phylogenomic databases

Enzyme and pathway databases

Miscellaneous databases

Family and domain databases

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationⁱ

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousⁱ

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Technical termⁱ

Documents

1. SIMILARITY comments
   Index of protein domains and families
2. Yeast
   Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD
3. Yeast chromosome V
   Yeast (Saccharomyces cerevisiae) chromosome V: entries and gene names

<p>This section provides links to the UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>). UniRef consists of clusters for UniProtKB sequences (including isoforms) and selected UniParc sequences, in order to obtain complete coverage of the sequence space at resolutions of 100%, 90% and 50% identity.<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsⁱ