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P39955 (SAP1_YEAST) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 101. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (3) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Interactions·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Protein SAP1
Alternative name(s):
SIN1-associated protein
Gene names
Name:SAP1
Ordered Locus Names:YER047C
OrganismSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) [Reference proteome]
Taxonomic identifier559292 [NCBI]
Taxonomic lineageEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces

Protein attributes

Sequence length897 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

General annotation (Comments)

Subunit structure

Interacts with SPT2/SIN1.

Miscellaneous

Present with 300 molecules/cell in log phase SD medium.

Sequence similarities

Belongs to the AAA ATPase family.

Binary interactions

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 897897Protein SAP1
PRO_0000084761

Regions

Nucleotide binding645 – 6528ATP Potential

Amino acid modifications

Modified residue5361Phosphoserine Ref.7

Sequences

Sequence LengthMass (Da)Tools
P39955 [UniParc].

Last modified February 1, 1995. Version 1.
Checksum: E9780B269700144C

FASTA897100,332
        10         20         30         40         50         60 
MDSQRSHHIL TRLTKIRRRP QQPLTDFTEL YSRIANETIY YLNLEEKKRY KEALQGWKAL 

        70         80         90        100        110        120 
TTDVLFKQTL IEHNYPNTQS YTKDEVSLQN GIRELYHKSV MHLKRVKKLV REEPAPRNDM 

       130        140        150        160        170        180 
PSSKTYTNHS SSFTRSTEPP PVFQMVPGRM MKTLRNRNAC GYKTAYSNPS LSSYGNSTSI 

       190        200        210        220        230        240 
KRGEDAENIR VNFVPSKPLS NNASRQHKNP IEHNDPPLKK ETELYSDKYI SEPILIDLTN 

       250        260        270        280        290        300 
DEDDHDVGIL KGHNVFDEEE SDGFEFDVSD YYDNFSEVDV EEEEEEKEER RRIKTLEAIQ 

       310        320        330        340        350        360 
QQMSDLSVTS STSSNKSVSS SENVPGSCIQ SLPTTAPALP SLPPPPLLNV DRASSTGALK 

       370        380        390        400        410        420 
PHSLETSTTM DSSKIRNPQI SKLMKNNHVP YLKGTKSTPT LITKSTPTFI TRSKSNTKPI 

       430        440        450        460        470        480 
IKSNASSPTS SLTVPNSVIQ KPKTAAMAAK RVLNSKKVAS NPALNTTKKS HPILKSKTAK 

       490        500        510        520        530        540 
VPNSSSKKTS SHPSRPVSNS KPYSHGASQN KKPSKNQTTS MSKTNRKIPA QKKIGSPKIE 

       550        560        570        580        590        600 
DVGTEDATEH ATSLNEQREE PEIDKKVLRE ILEDEIIDSL QGVDRQAAKQ IFAEIVVHGD 

       610        620        630        640        650        660 
EVHWDDIAGL ESAKYSLKEA VVYPFLRPDL FRGLREPVRG MLLFGPPGTG KTMLARAVAT 

       670        680        690        700        710        720 
ESHSTFFSIS ASSLTSKYLG ESEKLVRALF AIAKKLSPSI IFVDEIDSIM GSRNNENENE 

       730        740        750        760        770        780 
SSRRIKNEFL VQWSSLSSAA AGSNKSNTNN SDTNGDEDDT RVLVLAATNL PWSIDEAARR 

       790        800        810        820        830        840 
RFVRRQYIPL PEDQTRHVQF KKLLSHQKHT LTESDFDELV KITEGYSGSD ITSLAKDAAM 

       850        860        870        880        890 
GPLRDLGDKL LETEREMIRP IGLVDFKNSL VYIKPSVSQD GLVKYEKWAS QFGSSGS 

« Hide

References

« Hide 'large scale' references
[1]"The nucleotide sequence of Saccharomyces cerevisiae chromosome V."
Dietrich F.S., Mulligan J.T., Hennessy K.M., Yelton M.A., Allen E., Araujo R., Aviles E., Berno A., Brennan T., Carpenter J., Chen E., Cherry J.M., Chung E., Duncan M., Guzman E., Hartzell G., Hunicke-Smith S., Hyman R.W. expand/collapse author list , Kayser A., Komp C., Lashkari D., Lew H., Lin D., Mosedale D., Nakahara K., Namath A., Norgren R., Oefner P., Oh C., Petel F.X., Roberts D., Sehl P., Schramm S., Shogren T., Smith V., Taylor P., Wei Y., Botstein D., Davis R.W.
Nature 387:78-81(1997) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 204508 / S288c.
[2]Saccharomyces Genome Database
Submitted (DEC-2009) to the EMBL/GenBank/DDBJ databases
Cited for: GENOME REANNOTATION.
Strain: ATCC 204508 / S288c.
[3]"Association of yeast SAP1, a novel member of the 'AAA' ATPase family of proteins, with the chromatin protein SIN1."
Liberzon A., Shpungin S., Bangio H., Yona E., Katcoff D.J.
FEBS Lett. 388:5-10(1996) [PubMed] [Europe PMC] [Abstract]
Cited for: CHARACTERIZATION.
[4]"Global analysis of protein expression in yeast."
Ghaemmaghami S., Huh W.-K., Bower K., Howson R.W., Belle A., Dephoure N., O'Shea E.K., Weissman J.S.
Nature 425:737-741(2003) [PubMed] [Europe PMC] [Abstract]
Cited for: LEVEL OF PROTEIN EXPRESSION [LARGE SCALE ANALYSIS].
[5]"Large-scale phosphorylation analysis of alpha-factor-arrested Saccharomyces cerevisiae."
Li X., Gerber S.A., Rudner A.D., Beausoleil S.A., Haas W., Villen J., Elias J.E., Gygi S.P.
J. Proteome Res. 6:1190-1197(2007) [PubMed] [Europe PMC] [Abstract]
Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
Strain: ADR376.
[6]"A multidimensional chromatography technology for in-depth phosphoproteome analysis."
Albuquerque C.P., Smolka M.B., Payne S.H., Bafna V., Eng J., Zhou H.
Mol. Cell. Proteomics 7:1389-1396(2008) [PubMed] [Europe PMC] [Abstract]
Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
[7]"Global analysis of Cdk1 substrate phosphorylation sites provides insights into evolution."
Holt L.J., Tuch B.B., Villen J., Johnson A.D., Gygi S.P., Morgan D.O.
Science 325:1682-1686(2009) [PubMed] [Europe PMC] [Abstract]
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-536, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
U18796 Genomic DNA. Translation: AAB64582.1.
BK006939 Genomic DNA. Translation: DAA07702.1.
PIRS50550.
RefSeqNP_010966.1. NM_001178938.1.

3D structure databases

ProteinModelPortalP39955.
SMRP39955. Positions 580-895.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

BioGrid36784. 33 interactions.
DIPDIP-1550N.
IntActP39955. 15 interactions.
MINTMINT-407680.
STRING4932.YER047C.

Proteomic databases

PaxDbP39955.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblFungiYER047C; YER047C; YER047C.
GeneID856771.
KEGGsce:YER047C.

Organism-specific databases

CYGDYER047c.
SGDS000000849. SAP1.

Phylogenomic databases

eggNOGCOG0464.
GeneTreeENSGT00570000078874.
HOGENOMHOG000216613.
OMAHGDEVHW.
OrthoDBEOG72JWRT.

Enzyme and pathway databases

BioCycYEAST:G3O-30226-MONOMER.

Gene expression databases

GenevestigatorP39955.

Family and domain databases

Gene3D3.40.50.300. 1 hit.
InterProIPR003593. AAA+_ATPase.
IPR003959. ATPase_AAA_core.
IPR003960. ATPase_AAA_CS.
IPR027417. P-loop_NTPase.
[Graphical view]
PfamPF00004. AAA. 1 hit.
[Graphical view]
SMARTSM00382. AAA. 1 hit.
[Graphical view]
SUPFAMSSF52540. SSF52540. 1 hit.
PROSITEPS00674. AAA. 1 hit.
[Graphical view]
ProtoNetSearch...

Other

NextBio982962.

Entry information

Entry nameSAP1_YEAST
AccessionPrimary (citable) accession number: P39955
Secondary accession number(s): D3DLU8
Entry history
Integrated into UniProtKB/Swiss-Prot: February 1, 1995
Last sequence update: February 1, 1995
Last modified: April 16, 2014
This is version 101 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Relevant documents

Yeast chromosome V

Yeast (Saccharomyces cerevisiae) chromosome V: entries and gene names

Yeast

Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD

SIMILARITY comments

Index of protein domains and families