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Protein

40S ribosomal protein S26-A

Gene

RPS26A

Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

  • mRNA binding Source: GO_Central
  • structural constituent of ribosome Source: SGD

GO - Biological processi

  • cytoplasmic translation Source: SGD
  • rRNA export from nucleus Source: SGD
Complete GO annotation...

Keywords - Molecular functioni

Ribonucleoprotein, Ribosomal protein

Enzyme and pathway databases

BioCyciYEAST:G3O-30672-MONOMER.
ReactomeiR-SCE-156827. L13a-mediated translational silencing of Ceruloplasmin expression.
R-SCE-1799339. SRP-dependent cotranslational protein targeting to membrane.
R-SCE-72689. Formation of a pool of free 40S subunits.
R-SCE-72695. Formation of the ternary complex, and subsequently, the 43S complex.
R-SCE-72702. Ribosomal scanning and start codon recognition.
R-SCE-72706. GTP hydrolysis and joining of the 60S ribosomal subunit.
R-SCE-975956. Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC).
R-SCE-975957. Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC).

Names & Taxonomyi

Protein namesi
Recommended name:
40S ribosomal protein S26-A
Gene namesi
Name:RPS26A
Synonyms:RPS26
Ordered Locus Names:YGL189C
ORF Names:G1355
OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Taxonomic identifieri559292 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
Proteomesi
  • UP000002311 Componenti: Chromosome VII

Organism-specific databases

EuPathDBiFungiDB:YGL189C.
SGDiS000003157. RPS26A.

Subcellular locationi

GO - Cellular componenti

  • cytosolic small ribosomal subunit Source: SGD
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 11911940S ribosomal protein S26-APRO_0000204528Add
BLAST

Proteomic databases

MaxQBiP39938.
PRIDEiP39938.

PTM databases

iPTMnetiP39938.

Interactioni

Subunit structurei

Component of the small ribosomal subunit. Mature ribosomes consist of a small (40S) and a large (60S) subunit. The 40S subunit contains 32 different proteins (encoded by 56 genes) and 1 molecule of RNA (18S). The 60S subunit contains 46 different proteins (encoded by 81 genes) and 3 molecules of RNA (25S, 5.8S and 5S). Interacts with TSR2.3 Publications

Protein-protein interaction databases

BioGridi33067. 36 interactions.
DIPiDIP-1396N.
IntActiP39938. 8 interactions.
MINTiMINT-383624.

Structurei

Secondary structure

1
119
Legend: HelixTurnBeta strand
Show more details
Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Beta strandi8 – 114Combined sources
Beta strandi20 – 223Combined sources
Turni24 – 263Combined sources
Beta strandi29 – 313Combined sources
Helixi32 – 343Combined sources
Beta strandi37 – 426Combined sources
Turni47 – 493Combined sources
Helixi50 – 556Combined sources
Beta strandi59 – 613Combined sources
Beta strandi67 – 726Combined sources
Helixi76 – 805Combined sources
Turni89 – 924Combined sources

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
3J6Xelectron microscopy6.10261-119[»]
3J6Yelectron microscopy6.10261-119[»]
3J77electron microscopy6.20261-119[»]
3J78electron microscopy6.30261-119[»]
3V88X-ray3.00a1-119[»]
4V88X-ray3.00Aa/Ca1-119[»]
4V8Yelectron microscopy4.30A01-119[»]
4V8Zelectron microscopy6.60A01-119[»]
4V92electron microscopy3.70a2-98[»]
5FCIX-ray3.40D6/d62-98[»]
ProteinModelPortaliP39938.
SMRiP39938. Positions 2-98.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the ribosomal protein S26e family.Curated

Phylogenomic databases

GeneTreeiENSGT00390000002517.
HOGENOMiHOG000108824.
InParanoidiP39938.
KOiK02976.
OMAiVRCLNCA.
OrthoDBiEOG092C5TXE.

Family and domain databases

InterProiIPR000892. Ribosomal_S26e.
[Graphical view]
PANTHERiPTHR12538. PTHR12538. 1 hit.
PfamiPF01283. Ribosomal_S26e. 1 hit.
[Graphical view]
PROSITEiPS00733. RIBOSOMAL_S26E. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P39938-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MPKKRASNGR NKKGRGHVKP VRCVNCSKSI PKDKAIKRMA IRNIVEAAAV
60 70 80 90 100
RDLSEASVYP EYALPKTYNK LHYCVSCAIH ARIVRVRSRE DRKNRAPPQR
110
PRFNRENKVS PADAAKKAL
Length:119
Mass (Da):13,505
Last modified:February 1, 1995 - v1
Checksum:i2BB61CF9B233E3FE
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U10563 Genomic DNA. Translation: AAA66066.1.
X91489 Genomic DNA. Translation: CAA62786.1.
Z72711 Genomic DNA. Translation: CAA96901.1.
EF123138 mRNA. Translation: ABM97482.1.
BK006941 Genomic DNA. Translation: DAA07926.1.
PIRiS47942.
RefSeqiNP_011326.1. NM_001181054.1.

Genome annotation databases

EnsemblFungiiYGL189C; YGL189C; YGL189C.
GeneIDi852686.
KEGGisce:YGL189C.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U10563 Genomic DNA. Translation: AAA66066.1.
X91489 Genomic DNA. Translation: CAA62786.1.
Z72711 Genomic DNA. Translation: CAA96901.1.
EF123138 mRNA. Translation: ABM97482.1.
BK006941 Genomic DNA. Translation: DAA07926.1.
PIRiS47942.
RefSeqiNP_011326.1. NM_001181054.1.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
3J6Xelectron microscopy6.10261-119[»]
3J6Yelectron microscopy6.10261-119[»]
3J77electron microscopy6.20261-119[»]
3J78electron microscopy6.30261-119[»]
3V88X-ray3.00a1-119[»]
4V88X-ray3.00Aa/Ca1-119[»]
4V8Yelectron microscopy4.30A01-119[»]
4V8Zelectron microscopy6.60A01-119[»]
4V92electron microscopy3.70a2-98[»]
5FCIX-ray3.40D6/d62-98[»]
ProteinModelPortaliP39938.
SMRiP39938. Positions 2-98.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi33067. 36 interactions.
DIPiDIP-1396N.
IntActiP39938. 8 interactions.
MINTiMINT-383624.

PTM databases

iPTMnetiP39938.

Proteomic databases

MaxQBiP39938.
PRIDEiP39938.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblFungiiYGL189C; YGL189C; YGL189C.
GeneIDi852686.
KEGGisce:YGL189C.

Organism-specific databases

EuPathDBiFungiDB:YGL189C.
SGDiS000003157. RPS26A.

Phylogenomic databases

GeneTreeiENSGT00390000002517.
HOGENOMiHOG000108824.
InParanoidiP39938.
KOiK02976.
OMAiVRCLNCA.
OrthoDBiEOG092C5TXE.

Enzyme and pathway databases

BioCyciYEAST:G3O-30672-MONOMER.
ReactomeiR-SCE-156827. L13a-mediated translational silencing of Ceruloplasmin expression.
R-SCE-1799339. SRP-dependent cotranslational protein targeting to membrane.
R-SCE-72689. Formation of a pool of free 40S subunits.
R-SCE-72695. Formation of the ternary complex, and subsequently, the 43S complex.
R-SCE-72702. Ribosomal scanning and start codon recognition.
R-SCE-72706. GTP hydrolysis and joining of the 60S ribosomal subunit.
R-SCE-975956. Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC).
R-SCE-975957. Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC).

Miscellaneous databases

PROiP39938.

Family and domain databases

InterProiIPR000892. Ribosomal_S26e.
[Graphical view]
PANTHERiPTHR12538. PTHR12538. 1 hit.
PfamiPF01283. Ribosomal_S26e. 1 hit.
[Graphical view]
PROSITEiPS00733. RIBOSOMAL_S26E. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiRS26A_YEAST
AccessioniPrimary (citable) accession number: P39938
Secondary accession number(s): A2TBN5, D6VTW5
Entry historyi
Integrated into UniProtKB/Swiss-Prot: February 1, 1995
Last sequence update: February 1, 1995
Last modified: September 7, 2016
This is version 125 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Miscellaneous

Present with 16300 molecules/cell in log phase SD medium.1 Publication
There are 2 genes for S26 in yeast.

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome

Documents

  1. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  2. Ribosomal proteins
    Ribosomal proteins families and list of entries
  3. SIMILARITY comments
    Index of protein domains and families
  4. Yeast
    Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD
  5. Yeast chromosome VII
    Yeast (Saccharomyces cerevisiae) chromosome VII: entries and gene names

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.