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Protein

40S ribosomal protein S26-A

Gene

RPS26A

Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

  • mRNA binding Source: GO_Central
  • structural constituent of ribosome Source: SGD

GO - Biological processi

  • cytoplasmic translation Source: SGD
  • rRNA export from nucleus Source: SGD
Complete GO annotation...

Keywords - Molecular functioni

Ribonucleoprotein, Ribosomal protein

Enzyme and pathway databases

BioCyciYEAST:G3O-30672-MONOMER.
ReactomeiR-SCE-156827. L13a-mediated translational silencing of Ceruloplasmin expression.
R-SCE-1799339. SRP-dependent cotranslational protein targeting to membrane.
R-SCE-72689. Formation of a pool of free 40S subunits.
R-SCE-72695. Formation of the ternary complex, and subsequently, the 43S complex.
R-SCE-72702. Ribosomal scanning and start codon recognition.
R-SCE-72706. GTP hydrolysis and joining of the 60S ribosomal subunit.
R-SCE-975956. Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC).
R-SCE-975957. Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC).

Names & Taxonomyi

Protein namesi
Recommended name:
40S ribosomal protein S26-A
Gene namesi
Name:RPS26A
Synonyms:RPS26
Ordered Locus Names:YGL189C
ORF Names:G1355
OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Taxonomic identifieri559292 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
Proteomesi
  • UP000002311 Componenti: Chromosome VII

Organism-specific databases

EuPathDBiFungiDB:YGL189C.
SGDiS000003157. RPS26A.

Subcellular locationi

GO - Cellular componenti

  • cytosolic small ribosomal subunit Source: SGD
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 11911940S ribosomal protein S26-APRO_0000204528Add
BLAST

Proteomic databases

MaxQBiP39938.
PRIDEiP39938.

PTM databases

iPTMnetiP39938.

Interactioni

Subunit structurei

Component of the small ribosomal subunit. Mature ribosomes consist of a small (40S) and a large (60S) subunit. The 40S subunit contains 32 different proteins (encoded by 56 genes) and 1 molecule of RNA (18S). The 60S subunit contains 46 different proteins (encoded by 81 genes) and 3 molecules of RNA (25S, 5.8S and 5S). Interacts with TSR2.3 Publications

Protein-protein interaction databases

BioGridi33067. 36 interactions.
DIPiDIP-1396N.
IntActiP39938. 8 interactions.
MINTiMINT-383624.

Structurei

Secondary structure

1
119
Legend: HelixTurnBeta strand
Show more details
Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Beta strandi8 – 114Combined sources
Beta strandi20 – 223Combined sources
Turni24 – 263Combined sources
Beta strandi29 – 313Combined sources
Helixi32 – 343Combined sources
Beta strandi37 – 426Combined sources
Turni47 – 493Combined sources
Helixi50 – 556Combined sources
Beta strandi59 – 613Combined sources
Beta strandi67 – 726Combined sources
Helixi76 – 805Combined sources
Turni89 – 924Combined sources

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
3J6Xelectron microscopy6.10261-119[»]
3J6Yelectron microscopy6.10261-119[»]
3J77electron microscopy6.20261-119[»]
3J78electron microscopy6.30261-119[»]
3V88X-ray3.00a1-119[»]
4V88X-ray3.00Aa/Ca1-119[»]
4V8Yelectron microscopy4.30A01-119[»]
4V8Zelectron microscopy6.60A01-119[»]
4V92electron microscopy3.70a2-98[»]
5FCIX-ray3.40D6/d62-98[»]
ProteinModelPortaliP39938.
SMRiP39938. Positions 2-98.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the ribosomal protein S26e family.Curated

Phylogenomic databases

GeneTreeiENSGT00390000002517.
HOGENOMiHOG000108824.
InParanoidiP39938.
KOiK02976.
OMAiYIRLAYC.
OrthoDBiEOG72RNB6.

Family and domain databases

InterProiIPR000892. Ribosomal_S26e.
[Graphical view]
PANTHERiPTHR12538. PTHR12538. 1 hit.
PfamiPF01283. Ribosomal_S26e. 1 hit.
[Graphical view]
PROSITEiPS00733. RIBOSOMAL_S26E. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P39938-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MPKKRASNGR NKKGRGHVKP VRCVNCSKSI PKDKAIKRMA IRNIVEAAAV
60 70 80 90 100
RDLSEASVYP EYALPKTYNK LHYCVSCAIH ARIVRVRSRE DRKNRAPPQR
110
PRFNRENKVS PADAAKKAL
Length:119
Mass (Da):13,505
Last modified:February 1, 1995 - v1
Checksum:i2BB61CF9B233E3FE
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U10563 Genomic DNA. Translation: AAA66066.1.
X91489 Genomic DNA. Translation: CAA62786.1.
Z72711 Genomic DNA. Translation: CAA96901.1.
EF123138 mRNA. Translation: ABM97482.1.
BK006941 Genomic DNA. Translation: DAA07926.1.
PIRiS47942.
RefSeqiNP_011326.1. NM_001181054.1.

Genome annotation databases

EnsemblFungiiYGL189C; YGL189C; YGL189C.
GeneIDi852686.
KEGGisce:YGL189C.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U10563 Genomic DNA. Translation: AAA66066.1.
X91489 Genomic DNA. Translation: CAA62786.1.
Z72711 Genomic DNA. Translation: CAA96901.1.
EF123138 mRNA. Translation: ABM97482.1.
BK006941 Genomic DNA. Translation: DAA07926.1.
PIRiS47942.
RefSeqiNP_011326.1. NM_001181054.1.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
3J6Xelectron microscopy6.10261-119[»]
3J6Yelectron microscopy6.10261-119[»]
3J77electron microscopy6.20261-119[»]
3J78electron microscopy6.30261-119[»]
3V88X-ray3.00a1-119[»]
4V88X-ray3.00Aa/Ca1-119[»]
4V8Yelectron microscopy4.30A01-119[»]
4V8Zelectron microscopy6.60A01-119[»]
4V92electron microscopy3.70a2-98[»]
5FCIX-ray3.40D6/d62-98[»]
ProteinModelPortaliP39938.
SMRiP39938. Positions 2-98.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi33067. 36 interactions.
DIPiDIP-1396N.
IntActiP39938. 8 interactions.
MINTiMINT-383624.

PTM databases

iPTMnetiP39938.

Proteomic databases

MaxQBiP39938.
PRIDEiP39938.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblFungiiYGL189C; YGL189C; YGL189C.
GeneIDi852686.
KEGGisce:YGL189C.

Organism-specific databases

EuPathDBiFungiDB:YGL189C.
SGDiS000003157. RPS26A.

Phylogenomic databases

GeneTreeiENSGT00390000002517.
HOGENOMiHOG000108824.
InParanoidiP39938.
KOiK02976.
OMAiYIRLAYC.
OrthoDBiEOG72RNB6.

Enzyme and pathway databases

BioCyciYEAST:G3O-30672-MONOMER.
ReactomeiR-SCE-156827. L13a-mediated translational silencing of Ceruloplasmin expression.
R-SCE-1799339. SRP-dependent cotranslational protein targeting to membrane.
R-SCE-72689. Formation of a pool of free 40S subunits.
R-SCE-72695. Formation of the ternary complex, and subsequently, the 43S complex.
R-SCE-72702. Ribosomal scanning and start codon recognition.
R-SCE-72706. GTP hydrolysis and joining of the 60S ribosomal subunit.
R-SCE-975956. Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC).
R-SCE-975957. Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC).

Miscellaneous databases

PROiP39938.

Family and domain databases

InterProiIPR000892. Ribosomal_S26e.
[Graphical view]
PANTHERiPTHR12538. PTHR12538. 1 hit.
PfamiPF01283. Ribosomal_S26e. 1 hit.
[Graphical view]
PROSITEiPS00733. RIBOSOMAL_S26E. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "The Saccharomyces cerevisiae homologue of ribosomal protein S26."
    Wu M., Tan H.
    Gene 150:401-402(1994) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
  2. "Sequencing of a 40.5 kb fragment located on the left arm of chromosome VII from Saccharomyces cerevisiae."
    Coglievina M., Klima R., Bertani I., Delneri D., Zaccaria P., Bruschi C.V.
    Yeast 13:55-64(1997) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
    Strain: ATCC 96604 / S288c / FY1679.
  3. "The nucleotide sequence of Saccharomyces cerevisiae chromosome VII."
    Tettelin H., Agostoni-Carbone M.L., Albermann K., Albers M., Arroyo J., Backes U., Barreiros T., Bertani I., Bjourson A.J., Brueckner M., Bruschi C.V., Carignani G., Castagnoli L., Cerdan E., Clemente M.L., Coblenz A., Coglievina M., Coissac E.
    , Defoor E., Del Bino S., Delius H., Delneri D., de Wergifosse P., Dujon B., Durand P., Entian K.-D., Eraso P., Escribano V., Fabiani L., Fartmann B., Feroli F., Feuermann M., Frontali L., Garcia-Gonzalez M., Garcia-Saez M.I., Goffeau A., Guerreiro P., Hani J., Hansen M., Hebling U., Hernandez K., Heumann K., Hilger F., Hofmann B., Indge K.J., James C.M., Klima R., Koetter P., Kramer B., Kramer W., Lauquin G., Leuther H., Louis E.J., Maillier E., Marconi A., Martegani E., Mazon M.J., Mazzoni C., McReynolds A.D.K., Melchioretto P., Mewes H.-W., Minenkova O., Mueller-Auer S., Nawrocki A., Netter P., Neu R., Nombela C., Oliver S.G., Panzeri L., Paoluzi S., Plevani P., Portetelle D., Portillo F., Potier S., Purnelle B., Rieger M., Riles L., Rinaldi T., Robben J., Rodrigues-Pousada C., Rodriguez-Belmonte E., Rodriguez-Torres A.M., Rose M., Ruzzi M., Saliola M., Sanchez-Perez M., Schaefer B., Schaefer M., Scharfe M., Schmidheini T., Schreer A., Skala J., Souciet J.-L., Steensma H.Y., Talla E., Thierry A., Vandenbol M., van der Aart Q.J.M., Van Dyck L., Vanoni M., Verhasselt P., Voet M., Volckaert G., Wambutt R., Watson M.D., Weber N., Wedler E., Wedler H., Wipfli P., Wolf K., Wright L.F., Zaccaria P., Zimmermann M., Zollner A., Kleine K.
    Nature 387:81-84(1997) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 204508 / S288c.
  4. Cited for: GENOME REANNOTATION.
    Strain: ATCC 204508 / S288c.
  5. "High-density yeast-tiling array reveals previously undiscovered introns and extensive regulation of meiotic splicing."
    Juneau K., Palm C., Miranda M., Davis R.W.
    Proc. Natl. Acad. Sci. U.S.A. 104:1522-1527(2007) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 1-88.
    Strain: ATCC 201390 / BY4743.
  6. "The list of cytoplasmic ribosomal proteins of Saccharomyces cerevisiae."
    Planta R.J., Mager W.H.
    Yeast 14:471-477(1998) [PubMed] [Europe PMC] [Abstract]
    Cited for: NOMENCLATURE, SUBUNIT.
  7. Cited for: INTERACTION WITH TSR2.
  8. Cited for: INTERACTION WITH TSR2.
  9. Cited for: SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS].
  10. Cited for: LEVEL OF PROTEIN EXPRESSION [LARGE SCALE ANALYSIS].

Entry informationi

Entry nameiRS26A_YEAST
AccessioniPrimary (citable) accession number: P39938
Secondary accession number(s): A2TBN5, D6VTW5
Entry historyi
Integrated into UniProtKB/Swiss-Prot: February 1, 1995
Last sequence update: February 1, 1995
Last modified: July 6, 2016
This is version 124 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Miscellaneous

Present with 16300 molecules/cell in log phase SD medium.1 Publication
There are 2 genes for S26 in yeast.

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome

Documents

  1. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  2. Ribosomal proteins
    Ribosomal proteins families and list of entries
  3. SIMILARITY comments
    Index of protein domains and families
  4. Yeast
    Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD
  5. Yeast chromosome VII
    Yeast (Saccharomyces cerevisiae) chromosome VII: entries and gene names

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.