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P39932

- STL1_YEAST

UniProt

P39932 - STL1_YEAST

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Protein

Sugar transporter STL1

Gene
STL1, YDR536W, D9719.39
Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed - Annotation score: 3 out of 5 - Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

  1. solute:proton symporter activity Source: SGD

GO - Biological processi

  1. glycerol transport Source: SGD
  2. proton transport Source: GOC
  3. transmembrane transport Source: SGD
Complete GO annotation...

Keywords - Biological processi

Sugar transport, Transport

Enzyme and pathway databases

BioCyciYEAST:G3O-30046-MONOMER.

Protein family/group databases

TCDBi2.A.1.1.38. the major facilitator superfamily (mfs).

Names & Taxonomyi

Protein namesi
Recommended name:
Sugar transporter STL1
Gene namesi
Name:STL1
Ordered Locus Names:YDR536W
ORF Names:D9719.39
OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Taxonomic identifieri559292 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
ProteomesiUP000002311: Chromosome IV

Organism-specific databases

CYGDiYDR536w.
SGDiS000002944. STL1.

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Topological domaini1 – 2929Cytoplasmic Reviewed predictionAdd
BLAST
Transmembranei30 – 5021Helical; Name=1; Reviewed predictionAdd
BLAST
Topological domaini51 – 7929Extracellular Reviewed predictionAdd
BLAST
Transmembranei80 – 10021Helical; Name=2; Reviewed predictionAdd
BLAST
Topological domaini101 – 1077Cytoplasmic Reviewed prediction
Transmembranei108 – 12821Helical; Name=3; Reviewed predictionAdd
BLAST
Topological domaini129 – 1291Extracellular Reviewed prediction
Transmembranei130 – 15021Helical; Name=4; Reviewed predictionAdd
BLAST
Topological domaini151 – 16818Cytoplasmic Reviewed predictionAdd
BLAST
Transmembranei169 – 18921Helical; Name=5; Reviewed predictionAdd
BLAST
Topological domaini190 – 20314Extracellular Reviewed predictionAdd
BLAST
Transmembranei204 – 22421Helical; Name=6; Reviewed predictionAdd
BLAST
Topological domaini225 – 29167Cytoplasmic Reviewed predictionAdd
BLAST
Transmembranei292 – 31221Helical; Name=7; Reviewed predictionAdd
BLAST
Topological domaini313 – 33018Extracellular Reviewed predictionAdd
BLAST
Transmembranei331 – 35121Helical; Name=8; Reviewed predictionAdd
BLAST
Topological domaini352 – 3587Cytoplasmic Reviewed prediction
Transmembranei359 – 37921Helical; Name=9; Reviewed predictionAdd
BLAST
Topological domaini380 – 38910Extracellular Reviewed prediction
Transmembranei390 – 41021Helical; Name=10; Reviewed predictionAdd
BLAST
Topological domaini411 – 42616Cytoplasmic Reviewed predictionAdd
BLAST
Transmembranei427 – 44721Helical; Name=11; Reviewed predictionAdd
BLAST
Topological domaini448 – 4536Extracellular Reviewed prediction
Transmembranei454 – 47421Helical; Name=12; Reviewed predictionAdd
BLAST
Topological domaini475 – 56995Cytoplasmic Reviewed predictionAdd
BLAST

GO - Cellular componenti

  1. integral component of membrane Source: UniProtKB-KW
  2. plasma membrane Source: SGD
Complete GO annotation...

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 569569Sugar transporter STL1PRO_0000050461Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Glycosylationi197 – 1971N-linked (GlcNAc...) Reviewed prediction
Glycosylationi319 – 3191N-linked (GlcNAc...) Reviewed prediction

Keywords - PTMi

Glycoprotein

Expressioni

Gene expression databases

GenevestigatoriP39932.

Interactioni

Protein-protein interaction databases

BioGridi32584. 28 interactions.
DIPiDIP-5275N.
IntActiP39932. 1 interaction.
MINTiMINT-551224.
STRINGi4932.YDR536W.

Structurei

3D structure databases

ProteinModelPortaliP39932.
SMRiP39932. Positions 29-488.

Family & Domainsi

Sequence similaritiesi

Keywords - Domaini

Repeat, Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiCOG0477.
GeneTreeiENSGT00720000108754.
HOGENOMiHOG000167080.
OMAiVITEVAM.
OrthoDBiEOG73JM4H.

Family and domain databases

InterProiIPR020846. MFS_dom.
IPR016196. MFS_dom_general_subst_transpt.
IPR005828. Sub_transporter.
IPR003663. Sugar/inositol_transpt.
IPR005829. Sugar_transporter_CS.
[Graphical view]
PfamiPF00083. Sugar_tr. 1 hit.
[Graphical view]
PRINTSiPR00171. SUGRTRNSPORT.
SUPFAMiSSF103473. SSF103473. 2 hits.
TIGRFAMsiTIGR00879. SP. 1 hit.
PROSITEiPS50850. MFS. 1 hit.
PS00216. SUGAR_TRANSPORT_1. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P39932-1 [UniParc]FASTAAdd to Basket

« Hide

MKDLKLSNFK GKFISRTSHW GLTGKKLRYF ITIASMTGFS LFGYDQGLMA    50
SLITGKQFNY EFPATKENGD HDRHATVVQG ATTSCYELGC FAGSLFVMFC 100
GERIGRKPLI LMGSVITIIG AVISTCAFRG YWALGQFIIG RVVTGVGTGL 150
NTSTIPVWQS EMSKAENRGL LVNLEGSTIA FGTMIAYWID FGLSYTNSSV 200
QWRFPVSMQI VFALFLLAFM IKLPESPRWL ISQSRTEEAR YLVGTLDDAD 250
PNDEEVITEV AMLHDAVNRT KHEKHSLSSL FSRGRSQNLQ RALIAASTQF 300
FQQFTGCNAA IYYSTVLFNK TIKLDYRLSM IIGGVFATIY ALSTIGSFFL 350
IEKLGRRKLF LLGATGQAVS FTITFACLVK ENKENARGAA VGLFLFITFF 400
GLSLLSLPWI YPPEIASMKV RASTNAFSTC TNWLCNFAVV MFTPIFIGQS 450
GWGCYLFFAV MNYLYIPVIF FFYPETAGRS LEEIDIIFAK AYEDGTQPWR 500
VANHLPKLSL QEVEDHANAL GSYDDEMEKE DFGEDRVEDT YNQINGDNSS 550
SSSNIKNEDT VNDKANFEG 569
Length:569
Mass (Da):63,532
Last modified:October 1, 1996 - v2
Checksum:i053F3C546F84F056
GO

Sequence cautioni

The sequence AAA57229.1 differs from that shown. Reason: Frameshift at position 537.

Sequence conflict

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti237 – 2371E → G in AAU09713. 1 Publication

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
L07492 Genomic DNA. Translation: AAA57229.1. Frameshift.
U33057 Genomic DNA. Translation: AAB64975.1.
AY723796 Genomic DNA. Translation: AAU09713.1.
BK006938 Genomic DNA. Translation: DAA12366.1.
PIRiS69591.
RefSeqiNP_010825.3. NM_001180844.3.

Genome annotation databases

EnsemblFungiiYDR536W; YDR536W; YDR536W.
GeneIDi852149.
KEGGisce:YDR536W.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
L07492 Genomic DNA. Translation: AAA57229.1 . Frameshift.
U33057 Genomic DNA. Translation: AAB64975.1 .
AY723796 Genomic DNA. Translation: AAU09713.1 .
BK006938 Genomic DNA. Translation: DAA12366.1 .
PIRi S69591.
RefSeqi NP_010825.3. NM_001180844.3.

3D structure databases

ProteinModelPortali P39932.
SMRi P39932. Positions 29-488.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

BioGridi 32584. 28 interactions.
DIPi DIP-5275N.
IntActi P39932. 1 interaction.
MINTi MINT-551224.
STRINGi 4932.YDR536W.

Protein family/group databases

TCDBi 2.A.1.1.38. the major facilitator superfamily (mfs).

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblFungii YDR536W ; YDR536W ; YDR536W .
GeneIDi 852149.
KEGGi sce:YDR536W.

Organism-specific databases

CYGDi YDR536w.
SGDi S000002944. STL1.

Phylogenomic databases

eggNOGi COG0477.
GeneTreei ENSGT00720000108754.
HOGENOMi HOG000167080.
OMAi VITEVAM.
OrthoDBi EOG73JM4H.

Enzyme and pathway databases

BioCyci YEAST:G3O-30046-MONOMER.

Miscellaneous databases

NextBioi 970573.

Gene expression databases

Genevestigatori P39932.

Family and domain databases

InterProi IPR020846. MFS_dom.
IPR016196. MFS_dom_general_subst_transpt.
IPR005828. Sub_transporter.
IPR003663. Sugar/inositol_transpt.
IPR005829. Sugar_transporter_CS.
[Graphical view ]
Pfami PF00083. Sugar_tr. 1 hit.
[Graphical view ]
PRINTSi PR00171. SUGRTRNSPORT.
SUPFAMi SSF103473. SSF103473. 2 hits.
TIGRFAMsi TIGR00879. SP. 1 hit.
PROSITEi PS50850. MFS. 1 hit.
PS00216. SUGAR_TRANSPORT_1. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "The STL1 gene of Saccharomyces cerevisiae is predicted to encode a sugar transporter-like protein."
    Zhao S., Douglas N.W., Heine M.J., Williams G.M., Winther-Larsen H.C., Meaden P.G.
    Gene 146:215-219(1994) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
  2. "The nucleotide sequence of Saccharomyces cerevisiae chromosome IV."
    Jacq C., Alt-Moerbe J., Andre B., Arnold W., Bahr A., Ballesta J.P.G., Bargues M., Baron L., Becker A., Biteau N., Bloecker H., Blugeon C., Boskovic J., Brandt P., Brueckner M., Buitrago M.J., Coster F., Delaveau T.
    , del Rey F., Dujon B., Eide L.G., Garcia-Cantalejo J.M., Goffeau A., Gomez-Peris A., Granotier C., Hanemann V., Hankeln T., Hoheisel J.D., Jaeger W., Jimenez A., Jonniaux J.-L., Kraemer C., Kuester H., Laamanen P., Legros Y., Louis E.J., Moeller-Rieker S., Monnet A., Moro M., Mueller-Auer S., Nussbaumer B., Paricio N., Paulin L., Perea J., Perez-Alonso M., Perez-Ortin J.E., Pohl T.M., Prydz H., Purnelle B., Rasmussen S.W., Remacha M.A., Revuelta J.L., Rieger M., Salom D., Saluz H.P., Saiz J.E., Saren A.-M., Schaefer M., Scharfe M., Schmidt E.R., Schneider C., Scholler P., Schwarz S., Soler-Mira A., Urrestarazu L.A., Verhasselt P., Vissers S., Voet M., Volckaert G., Wagner G., Wambutt R., Wedler E., Wedler H., Woelfl S., Harris D.E., Bowman S., Brown D., Churcher C.M., Connor R., Dedman K., Gentles S., Hamlin N., Hunt S., Jones L., McDonald S., Murphy L.D., Niblett D., Odell C., Oliver K., Rajandream M.A., Richards C., Shore L., Walsh S.V., Barrell B.G., Dietrich F.S., Mulligan J.T., Allen E., Araujo R., Aviles E., Berno A., Carpenter J., Chen E., Cherry J.M., Chung E., Duncan M., Hunicke-Smith S., Hyman R.W., Komp C., Lashkari D., Lew H., Lin D., Mosedale D., Nakahara K., Namath A., Oefner P., Oh C., Petel F.X., Roberts D., Schramm S., Schroeder M., Shogren T., Shroff N., Winant A., Yelton M.A., Botstein D., Davis R.W., Johnston M., Andrews S., Brinkman R., Cooper J., Ding H., Du Z., Favello A., Fulton L., Gattung S., Greco T., Hallsworth K., Hawkins J., Hillier L.W., Jier M., Johnson D., Johnston L., Kirsten J., Kucaba T., Langston Y., Latreille P., Le T., Mardis E., Menezes S., Miller N., Nhan M., Pauley A., Peluso D., Rifkin L., Riles L., Taich A., Trevaskis E., Vignati D., Wilcox L., Wohldman P., Vaudin M., Wilson R., Waterston R., Albermann K., Hani J., Heumann K., Kleine K., Mewes H.-W., Zollner A., Zaccaria P.
    Nature 387:75-78(1997) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 204508 / S288c.
  3. Cited for: GENOME REANNOTATION.
    Strain: ATCC 204508 / S288c.
  4. Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
    Strain: ATCC 204508 / S288c.
  5. "A global topology map of the Saccharomyces cerevisiae membrane proteome."
    Kim H., Melen K., Oesterberg M., von Heijne G.
    Proc. Natl. Acad. Sci. U.S.A. 103:11142-11147(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: TOPOLOGY [LARGE SCALE ANALYSIS].
    Strain: ATCC 208353 / W303-1A.

Entry informationi

Entry nameiSTL1_YEAST
AccessioniPrimary (citable) accession number: P39932
Secondary accession number(s): D6VTF6, E9P950
Entry historyi
Integrated into UniProtKB/Swiss-Prot: February 1, 1995
Last sequence update: October 1, 1996
Last modified: July 9, 2014
This is version 119 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Yeast
    Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD
  3. Yeast chromosome IV
    Yeast (Saccharomyces cerevisiae) chromosome IV: entries and gene names

External Data

Dasty 3

Similar proteinsi