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Protein

Sugar transporter STL1

Gene

STL1

Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

  • glucose import Source: GO_Central
  • glycerol transport Source: SGD
  • transmembrane transport Source: SGD

Keywordsi

Biological processSugar transport, Transport

Enzyme and pathway databases

BioCyciYEAST:G3O-30046-MONOMER

Protein family/group databases

TCDBi2.A.1.1.38 the major facilitator superfamily (mfs)

Names & Taxonomyi

Protein namesi
Recommended name:
Sugar transporter STL1
Gene namesi
Name:STL1
Ordered Locus Names:YDR536W
ORF Names:D9719.39
OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Taxonomic identifieri559292 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
Proteomesi
  • UP000002311 Componenti: Chromosome IV

Organism-specific databases

EuPathDBiFungiDB:YDR536W
SGDiS000002944 STL1

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Topological domaini1 – 29CytoplasmicSequence analysisAdd BLAST29
Transmembranei30 – 50Helical; Name=1Sequence analysisAdd BLAST21
Topological domaini51 – 79ExtracellularSequence analysisAdd BLAST29
Transmembranei80 – 100Helical; Name=2Sequence analysisAdd BLAST21
Topological domaini101 – 107CytoplasmicSequence analysis7
Transmembranei108 – 128Helical; Name=3Sequence analysisAdd BLAST21
Topological domaini129ExtracellularSequence analysis1
Transmembranei130 – 150Helical; Name=4Sequence analysisAdd BLAST21
Topological domaini151 – 168CytoplasmicSequence analysisAdd BLAST18
Transmembranei169 – 189Helical; Name=5Sequence analysisAdd BLAST21
Topological domaini190 – 203ExtracellularSequence analysisAdd BLAST14
Transmembranei204 – 224Helical; Name=6Sequence analysisAdd BLAST21
Topological domaini225 – 291CytoplasmicSequence analysisAdd BLAST67
Transmembranei292 – 312Helical; Name=7Sequence analysisAdd BLAST21
Topological domaini313 – 330ExtracellularSequence analysisAdd BLAST18
Transmembranei331 – 351Helical; Name=8Sequence analysisAdd BLAST21
Topological domaini352 – 358CytoplasmicSequence analysis7
Transmembranei359 – 379Helical; Name=9Sequence analysisAdd BLAST21
Topological domaini380 – 389ExtracellularSequence analysis10
Transmembranei390 – 410Helical; Name=10Sequence analysisAdd BLAST21
Topological domaini411 – 426CytoplasmicSequence analysisAdd BLAST16
Transmembranei427 – 447Helical; Name=11Sequence analysisAdd BLAST21
Topological domaini448 – 453ExtracellularSequence analysis6
Transmembranei454 – 474Helical; Name=12Sequence analysisAdd BLAST21
Topological domaini475 – 569CytoplasmicSequence analysisAdd BLAST95

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000504611 – 569Sugar transporter STL1Add BLAST569

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Glycosylationi197N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi319N-linked (GlcNAc...) asparagineSequence analysis1

Keywords - PTMi

Glycoprotein

Proteomic databases

PaxDbiP39932

Interactioni

Protein-protein interaction databases

BioGridi32584, 77 interactors
DIPiDIP-5275N
IntActiP39932, 2 interactors
STRINGi4932.YDR536W

Structurei

3D structure databases

ProteinModelPortaliP39932
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Keywords - Domaini

Repeat, Transmembrane, Transmembrane helix

Phylogenomic databases

GeneTreeiENSGT00920000149265
HOGENOMiHOG000167080
InParanoidiP39932
OMAiFMKADVE
OrthoDBiEOG092C1Q5W

Family and domain databases

CDDicd06174 MFS, 1 hit
InterProiView protein in InterPro
IPR020846 MFS_dom
IPR005828 MFS_sugar_transport-like
IPR036259 MFS_trans_sf
IPR003663 Sugar/inositol_transpt
IPR005829 Sugar_transporter_CS
PfamiView protein in Pfam
PF00083 Sugar_tr, 1 hit
PRINTSiPR00171 SUGRTRNSPORT
SUPFAMiSSF103473 SSF103473, 2 hits
TIGRFAMsiTIGR00879 SP, 1 hit
PROSITEiView protein in PROSITE
PS50850 MFS, 1 hit
PS00216 SUGAR_TRANSPORT_1, 1 hit

Sequencei

Sequence statusi: Complete.

P39932-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKDLKLSNFK GKFISRTSHW GLTGKKLRYF ITIASMTGFS LFGYDQGLMA
60 70 80 90 100
SLITGKQFNY EFPATKENGD HDRHATVVQG ATTSCYELGC FAGSLFVMFC
110 120 130 140 150
GERIGRKPLI LMGSVITIIG AVISTCAFRG YWALGQFIIG RVVTGVGTGL
160 170 180 190 200
NTSTIPVWQS EMSKAENRGL LVNLEGSTIA FGTMIAYWID FGLSYTNSSV
210 220 230 240 250
QWRFPVSMQI VFALFLLAFM IKLPESPRWL ISQSRTEEAR YLVGTLDDAD
260 270 280 290 300
PNDEEVITEV AMLHDAVNRT KHEKHSLSSL FSRGRSQNLQ RALIAASTQF
310 320 330 340 350
FQQFTGCNAA IYYSTVLFNK TIKLDYRLSM IIGGVFATIY ALSTIGSFFL
360 370 380 390 400
IEKLGRRKLF LLGATGQAVS FTITFACLVK ENKENARGAA VGLFLFITFF
410 420 430 440 450
GLSLLSLPWI YPPEIASMKV RASTNAFSTC TNWLCNFAVV MFTPIFIGQS
460 470 480 490 500
GWGCYLFFAV MNYLYIPVIF FFYPETAGRS LEEIDIIFAK AYEDGTQPWR
510 520 530 540 550
VANHLPKLSL QEVEDHANAL GSYDDEMEKE DFGEDRVEDT YNQINGDNSS
560
SSSNIKNEDT VNDKANFEG
Length:569
Mass (Da):63,532
Last modified:October 1, 1996 - v2
Checksum:i053F3C546F84F056
GO

Sequence cautioni

The sequence AAA57229 differs from that shown. Reason: Frameshift at position 537.Curated

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti237E → G in AAU09713 (PubMed:17322287).Curated1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
L07492 Genomic DNA Translation: AAA57229.1 Frameshift.
U33057 Genomic DNA Translation: AAB64975.1
AY723796 Genomic DNA Translation: AAU09713.1
BK006938 Genomic DNA Translation: DAA12366.1
PIRiS69591
RefSeqiNP_010825.3, NM_001180844.3

Genome annotation databases

EnsemblFungiiYDR536W; YDR536W; YDR536W
GeneIDi852149
KEGGisce:YDR536W

Similar proteinsi

Entry informationi

Entry nameiSTL1_YEAST
AccessioniPrimary (citable) accession number: P39932
Secondary accession number(s): D6VTF6, E9P950
Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 1, 1995
Last sequence update: October 1, 1996
Last modified: June 20, 2018
This is version 153 of the entry and version 2 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

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