Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Basket 0
(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

P39924

- HXT13_YEAST

UniProt

P39924 - HXT13_YEAST

Protein

Hexose transporter HXT13

Gene

HXT13

Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed - Annotation score: 4 out of 5- Experimental evidence at protein leveli
    • BLAST
    • Align
    • Format
    • Add to basket
    • History
      Entry version 110 (01 Oct 2014)
      Sequence version 1 (01 Feb 1995)
      Previous versions | rss
    • Help video
    • Feedback
    • Comment

    Functioni

    Probable glucose transporter.

    GO - Molecular functioni

    1. fructose transmembrane transporter activity Source: SGD
    2. glucose transmembrane transporter activity Source: SGD
    3. mannose transmembrane transporter activity Source: SGD

    GO - Biological processi

    1. fructose transport Source: GOC
    2. glucose transport Source: GOC
    3. hexose transport Source: SGD
    4. mannose transport Source: GOC
    5. transmembrane transport Source: SGD

    Keywords - Biological processi

    Sugar transport, Transport

    Enzyme and pathway databases

    BioCyciYEAST:G3O-30184-MONOMER.

    Protein family/group databases

    TCDBi2.A.1.1.110. the major facilitator superfamily (mfs).

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Hexose transporter HXT13
    Gene namesi
    Name:HXT13
    Synonyms:HXT8
    Ordered Locus Names:YEL069C
    OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
    Taxonomic identifieri559292 [NCBI]
    Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
    ProteomesiUP000002311: Chromosome V

    Organism-specific databases

    CYGDiYEL069c.
    SGDiS000000795. HXT13.

    Subcellular locationi

    GO - Cellular componenti

    1. integral component of membrane Source: UniProtKB-KW
    2. plasma membrane Source: SGD

    Keywords - Cellular componenti

    Membrane

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 564564Hexose transporter HXT13PRO_0000050402Add
    BLAST

    Expressioni

    Gene expression databases

    GenevestigatoriP39924.

    Interactioni

    Protein-protein interaction databases

    DIPiDIP-3943N.
    MINTiMINT-530973.
    STRINGi4932.YEL069C.

    Structurei

    3D structure databases

    ProteinModelPortaliP39924.
    SMRiP39924. Positions 57-522.
    ModBaseiSearch...
    MobiDBiSearch...

    Topological domain

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Topological domaini1 – 5252CytoplasmicSequence AnalysisAdd
    BLAST
    Topological domaini74 – 10936ExtracellularSequence AnalysisAdd
    BLAST
    Topological domaini131 – 1366CytoplasmicSequence Analysis
    Topological domaini158 – 16710ExtracellularSequence Analysis
    Topological domaini189 – 1946CytoplasmicSequence Analysis
    Topological domaini216 – 22914ExtracellularSequence AnalysisAdd
    BLAST
    Topological domaini251 – 33383CytoplasmicSequence AnalysisAdd
    BLAST
    Topological domaini351 – 3566ExtracellularSequence Analysis
    Topological domaini375 – 3817CytoplasmicSequence Analysis
    Topological domaini403 – 42422ExtracellularSequence AnalysisAdd
    BLAST
    Topological domaini446 – 46217CytoplasmicSequence AnalysisAdd
    BLAST
    Topological domaini484 – 4841ExtracellularSequence Analysis
    Topological domaini506 – 56459CytoplasmicSequence AnalysisAdd
    BLAST

    Transmembrane

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Transmembranei53 – 7321Helical; Name=1Sequence AnalysisAdd
    BLAST
    Transmembranei110 – 13021Helical; Name=2Sequence AnalysisAdd
    BLAST
    Transmembranei137 – 15721Helical; Name=3Sequence AnalysisAdd
    BLAST
    Transmembranei168 – 18821Helical; Name=4Sequence AnalysisAdd
    BLAST
    Transmembranei195 – 21521Helical; Name=5Sequence AnalysisAdd
    BLAST
    Transmembranei230 – 25021Helical; Name=6Sequence AnalysisAdd
    BLAST
    Transmembranei334 – 35017Helical; Name=7Sequence AnalysisAdd
    BLAST
    Transmembranei357 – 37418Helical; Name=8Sequence AnalysisAdd
    BLAST
    Transmembranei382 – 40221Helical; Name=9Sequence AnalysisAdd
    BLAST
    Transmembranei425 – 44521Helical; Name=10Sequence AnalysisAdd
    BLAST
    Transmembranei463 – 48321Helical; Name=11Sequence AnalysisAdd
    BLAST
    Transmembranei485 – 50521Helical; Name=12Sequence AnalysisAdd
    BLAST

    Family & Domainsi

    Sequence similaritiesi

    Keywords - Domaini

    Repeat, Transmembrane, Transmembrane helix

    Phylogenomic databases

    GeneTreeiENSGT00720000108754.
    HOGENOMiHOG000202870.
    KOiK08139.
    OrthoDBiEOG73JM4H.

    Family and domain databases

    InterProiIPR020846. MFS_dom.
    IPR016196. MFS_dom_general_subst_transpt.
    IPR005828. Sub_transporter.
    IPR003663. Sugar/inositol_transpt.
    IPR005829. Sugar_transporter_CS.
    [Graphical view]
    PfamiPF00083. Sugar_tr. 1 hit.
    [Graphical view]
    PRINTSiPR00171. SUGRTRNSPORT.
    SUPFAMiSSF103473. SSF103473. 1 hit.
    TIGRFAMsiTIGR00879. SP. 1 hit.
    PROSITEiPS50850. MFS. 1 hit.
    PS00216. SUGAR_TRANSPORT_1. 1 hit.
    PS00217. SUGAR_TRANSPORT_2. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    P39924-1 [UniParc]FASTAAdd to Basket

    « Hide

    MSSAQSSIDS DGDVRDADIH VAPPVEKEWS DGFDDNEVIN GDNVEPPKRG    50
    LIGYLVIYLL CYPISFGGFL PGWDSGITAG FINMDNFKMN FGSYKHSTGE 100
    YYLSNVRMGL LVAMFSIGCA IGGLIFARLA DTLGRRLAIV IVVLVYMVGA 150
    IIQISSNHKW YQYFVGKIIY GLGAGGCSVL CPMLLSEIAP TDLRGGLVSL 200
    YQLNMTFGIF LGYCSVYGTR KYDNTAQWRV PLGLCFLWAL IIIIGMLLVP 250
    ESPRYLIECE RHEEARASIA KINKVSPEDP WVLKQADEIN AGVLAQRELG 300
    EASWKELFSV KTKVLQRLIT GILVQTFLQL TGENYFFFYG TTIFKSVGLT 350
    DGFETSIVLG TVNFFSTIIA VMVVDKIGRR KCLLFGAAGM MACMVIFASI 400
    GVKCLYPHGQ DGPSSKGAGN AMIVFTCFYI FCFATTWAPV AYIVVAESFP 450
    SKVKSRAMSI STACNWLWQF LIGFFTPFIT GSIHFYYGYV FVGCLVAMFL 500
    YVFFFLPETI GLSLEEIQLL YEEGIKPWKS ASWVPPSRRG ISSEESKTEK 550
    KDWKKFLKFS KNSD 564
    Length:564
    Mass (Da):62,734
    Last modified:February 1, 1995 - v1
    Checksum:iAEFFFF691718AB44
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    U18795 Genomic DNA. Translation: AAB65018.1.
    AY723801 Genomic DNA. Translation: AAU09718.1.
    BK006939 Genomic DNA. Translation: DAA07586.1.
    PIRiS50520.
    RefSeqiNP_010845.1. NM_001178884.1.

    Genome annotation databases

    EnsemblFungiiYEL069C; YEL069C; YEL069C.
    GeneIDi856640.
    KEGGisce:YEL069C.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    U18795 Genomic DNA. Translation: AAB65018.1 .
    AY723801 Genomic DNA. Translation: AAU09718.1 .
    BK006939 Genomic DNA. Translation: DAA07586.1 .
    PIRi S50520.
    RefSeqi NP_010845.1. NM_001178884.1.

    3D structure databases

    ProteinModelPortali P39924.
    SMRi P39924. Positions 57-522.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    DIPi DIP-3943N.
    MINTi MINT-530973.
    STRINGi 4932.YEL069C.

    Protein family/group databases

    TCDBi 2.A.1.1.110. the major facilitator superfamily (mfs).

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblFungii YEL069C ; YEL069C ; YEL069C .
    GeneIDi 856640.
    KEGGi sce:YEL069C.

    Organism-specific databases

    CYGDi YEL069c.
    SGDi S000000795. HXT13.

    Phylogenomic databases

    GeneTreei ENSGT00720000108754.
    HOGENOMi HOG000202870.
    KOi K08139.
    OrthoDBi EOG73JM4H.

    Enzyme and pathway databases

    BioCyci YEAST:G3O-30184-MONOMER.

    Miscellaneous databases

    NextBioi 982601.

    Gene expression databases

    Genevestigatori P39924.

    Family and domain databases

    InterProi IPR020846. MFS_dom.
    IPR016196. MFS_dom_general_subst_transpt.
    IPR005828. Sub_transporter.
    IPR003663. Sugar/inositol_transpt.
    IPR005829. Sugar_transporter_CS.
    [Graphical view ]
    Pfami PF00083. Sugar_tr. 1 hit.
    [Graphical view ]
    PRINTSi PR00171. SUGRTRNSPORT.
    SUPFAMi SSF103473. SSF103473. 1 hit.
    TIGRFAMsi TIGR00879. SP. 1 hit.
    PROSITEi PS50850. MFS. 1 hit.
    PS00216. SUGAR_TRANSPORT_1. 1 hit.
    PS00217. SUGAR_TRANSPORT_2. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC 204508 / S288c.
    2. Cited for: GENOME REANNOTATION.
      Strain: ATCC 204508 / S288c.
    3. Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
      Strain: ATCC 204508 / S288c.
    4. "A global topology map of the Saccharomyces cerevisiae membrane proteome."
      Kim H., Melen K., Oesterberg M., von Heijne G.
      Proc. Natl. Acad. Sci. U.S.A. 103:11142-11147(2006) [PubMed] [Europe PMC] [Abstract]
      Cited for: TOPOLOGY [LARGE SCALE ANALYSIS].
      Strain: ATCC 208353 / W303-1A.

    Entry informationi

    Entry nameiHXT13_YEAST
    AccessioniPrimary (citable) accession number: P39924
    Secondary accession number(s): D3DLI2
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: February 1, 1995
    Last sequence update: February 1, 1995
    Last modified: October 1, 2014
    This is version 110 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programFungal Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. SIMILARITY comments
      Index of protein domains and families
    2. Yeast
      Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD
    3. Yeast chromosome V
      Yeast (Saccharomyces cerevisiae) chromosome V: entries and gene names

    External Data

    Dasty 3