Hexose transporter HXT13 - Saccharomyces cerevisiae (Baker's yeast)

Contribute

Send feedback

Read comments (0) or add your own

Reviewed, UniProtKB/Swiss-Prot P39924 (HXT13_YEAST)

Last modified November 24, 2009. Version 72. History...

Clusters with 100%, 90%, 50% identity |

Documents (3) |

Third-party data |

Customize display

text xml rdf/xml gff fasta

Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents

Hide | Top

Names and origin

Protein names

Recommended name:
Hexose transporter HXT13

Gene names

Name:	HXT13
Synonyms:	HXT8
Ordered Locus Names:	YEL069C

Organism

Saccharomyces cerevisiae (Baker's yeast) [Complete proteome]

Taxonomic identifier

4932 [NCBI]

Taxonomic lineage

Eukaryota › Fungi › Dikarya › Ascomycota › Saccharomycotina › Saccharomycetes › Saccharomycetales › Saccharomycetaceae › Saccharomyces

Hide | Top

Protein attributes

Sequence length	564 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Evidence at protein level.

Hide | Top

General annotation (Comments)

Function	Probable glucose transporter.
Subcellular location	Membrane; Multi-pass membrane protein.
Sequence similarities	Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. [View classification]

Hide | Top

Ontologies

Keywords
Biological process	Sugar transport Transport
Cellular component	Membrane
Domain	Repeat Transmembrane
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	hexose transport Inferred from genetic interaction. Source: SGD transmembrane transport Inferred from genetic interaction. Source: SGD
Cellular component	integral to membrane Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	fructose transmembrane transporter activity Inferred from genetic interaction. Source: SGD glucose transmembrane transporter activity Inferred from genetic interaction. Source: SGD mannose transmembrane transporter activity Inferred from genetic interaction. Source: SGD
Complete GO annotation...

Hide | Top

Sequence annotation (Features)

Feature key

Position(s)

Length

Description

Graphical view

Feature identifier

Molecule processing

Chain

1 – 564

564

Hexose transporter HXT13

PRO_0000050402

Regions

Topological domain

1 – 52

Cytoplasmic Potential

Transmembrane

53 – 73

1 Potential

Topological domain

74 – 109

Extracellular Potential

Transmembrane

110 – 130

2 Potential

Topological domain

131 – 136

Cytoplasmic Potential

Transmembrane

137 – 157

3 Potential

Topological domain

158 – 167

Extracellular Potential

Transmembrane

168 – 188

4 Potential

Topological domain

189 – 194

Cytoplasmic Potential

Transmembrane

195 – 215

5 Potential

Topological domain

216 – 229

Extracellular Potential

Transmembrane

230 – 250

6 Potential

Topological domain

251 – 333

Cytoplasmic Potential

Transmembrane

334 – 350

7 Potential

Topological domain

351 – 356

Extracellular Potential

Transmembrane

357 – 374

8 Potential

Topological domain

375 – 381

Cytoplasmic Potential

Transmembrane

382 – 402

9 Potential

Topological domain

403 – 424

Extracellular Potential

Transmembrane

425 – 445

10 Potential

Topological domain

446 – 462

Cytoplasmic Potential

Transmembrane

463 – 483

11 Potential

Topological domain

484

Extracellular Potential

Transmembrane

485 – 505

12 Potential

Topological domain

506 – 564

Cytoplasmic Potential

Hide | Top

Sequences

Sequence

Length

Mass (Da)

Tools

P39924-1 [UniParc].

Last modified February 1, 1995. Version 1.
Checksum: AEFFFF691718AB44
Show »

FASTA

564

62,734

        10         20         30         40         50         60 
MSSAQSSIDS DGDVRDADIH VAPPVEKEWS DGFDDNEVIN GDNVEPPKRG LIGYLVIYLL 

        70         80         90        100        110        120 
CYPISFGGFL PGWDSGITAG FINMDNFKMN FGSYKHSTGE YYLSNVRMGL LVAMFSIGCA 

       130        140        150        160        170        180 
IGGLIFARLA DTLGRRLAIV IVVLVYMVGA IIQISSNHKW YQYFVGKIIY GLGAGGCSVL 

       190        200        210        220        230        240 
CPMLLSEIAP TDLRGGLVSL YQLNMTFGIF LGYCSVYGTR KYDNTAQWRV PLGLCFLWAL 

       250        260        270        280        290        300 
IIIIGMLLVP ESPRYLIECE RHEEARASIA KINKVSPEDP WVLKQADEIN AGVLAQRELG 

       310        320        330        340        350        360 
EASWKELFSV KTKVLQRLIT GILVQTFLQL TGENYFFFYG TTIFKSVGLT DGFETSIVLG 

       370        380        390        400        410        420 
TVNFFSTIIA VMVVDKIGRR KCLLFGAAGM MACMVIFASI GVKCLYPHGQ DGPSSKGAGN 

       430        440        450        460        470        480 
AMIVFTCFYI FCFATTWAPV AYIVVAESFP SKVKSRAMSI STACNWLWQF LIGFFTPFIT 

       490        500        510        520        530        540 
GSIHFYYGYV FVGCLVAMFL YVFFFLPETI GLSLEEIQLL YEEGIKPWKS ASWVPPSRRG 

       550        560 
ISSEESKTEK KDWKKFLKFS KNSD

« Hide

Hide | Top

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"The nucleotide sequence of Saccharomyces cerevisiae chromosome V." Dietrich F.S., Mulligan J.T., Hennessy K.M., Yelton M.A., Allen E., Araujo R., Aviles E., Berno A., Brennan T., Carpenter J., Chen E., Cherry J.M., Chung E., Duncan M., Guzman E., Hartzell G., Hunicke-Smith S., Hyman R.W. Davis R.W. Nature 387:78-81(1997) [PubMed: 9169868] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 204511 / S288c / AB972.
[2]	"Approaching a complete repository of sequence-verified protein-encoding clones for Saccharomyces cerevisiae." Hu Y., Rolfs A., Bhullar B., Murthy T.V.S., Zhu C., Berger M.F., Camargo A.A., Kelley F., McCarron S., Jepson D., Richardson A., Raphael J., Moreira D., Taycher E., Zuo D., Mohr S., Kane M.F., Williamson J. LaBaer J. Genome Res. 17:536-543(2007) [PubMed: 17322287] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]. Strain: ATCC 204508 / S288c.
[3]	"A global topology map of the Saccharomyces cerevisiae membrane proteome." Kim H., Melen K., Oesterberg M., von Heijne G. Proc. Natl. Acad. Sci. U.S.A. 103:11142-11147(2006) [PubMed: 16847258] [Abstract] Cited for: TOPOLOGY [LARGE SCALE ANALYSIS].
+	Additional computationally mapped references.

Hide | Top

Cross-references

Sequence databases
	U18795 Genomic DNA. Translation: AAB65018.1. AY723801 Genomic DNA. Translation: AAU09718.1.
PIR	S50520.
RefSeq	NP_010845.1.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
DIP	DIP:3943N.
IntAct	P39924. 3 interactions.
Genome annotation databases
Ensembl	YEL069C; YEL069C; YEL069C; Saccharomyces cerevisiae. [Genome view]
GeneID	856640.
KEGG	sce:YEL069C.
Organism-specific databases
CYGD	YEL069c.
SGD	S000000795. HXT13.
Phylogenomic databases
HOGENOM	P39924.
OrthoDB	EOG95HTDF
Gene expression databases
ArrayExpress	P39924.
Genevestigator	P39924.
GermOnline	YEL069C. Saccharomyces cerevisiae.
Family and domain databases
InterPro	IPR016196. MFS_general_subst_transpt. IPR005828. Sub_transporter. IPR003663. Sugar/inositol_transpt. IPR005829. Sugar_transporter_CS. [Graphical view]
Pfam	PF00083. Sugar_tr. 1 hit. [Graphical view]
PRINTS	PR00171. SUGRTRNSPORT.
TIGRFAMs	TIGR00879. SP. 1 hit.
PROSITE	PS50850. MFS. 1 hit. PS00216. SUGAR_TRANSPORT_1. 1 hit. PS00217. SUGAR_TRANSPORT_2. 1 hit. [Graphical view]
ProtoNet	Search...
Other Resources
NextBio	982601.

Hide | Top

Entry information

Entry name

HXT13_YEAST

Accession

Primary (citable) accession number: P39924

Entry history

Integrated into UniProtKB/Swiss-Prot:	February 1, 1995
Last sequence update:	February 1, 1995
Last modified:	November 24, 2009
This is version 72 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

FPAP (Fungal Proteome Annotation Project)

Hide | Top

Relevant documents

SIMILARITY comments

Index of protein domains and families

Yeast

Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD

Yeast chromosome V

Yeast (Saccharomyces cerevisiae) chromosome V: entries and gene names

Names and origin

Protein attributes

General annotation (Comments)

Ontologies

Sequence annotation (Features)

Molecule processing

Regions

Sequences

References

Cross-references

Sequence databases

3D structure databases

Protein-protein interaction databases

Genome annotation databases

Organism-specific databases

Phylogenomic databases

Gene expression databases

Family and domain databases

Other Resources

Entry information

Relevant documents