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Reviewed, UniProtKB/Swiss-Prot P39924 (HXT13_YEAST)

Last modified November 24, 2009. Version 72. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (3) | Third-party data | Customize display text xml rdf/xml gff fasta
Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents

Names and origin

Protein namesRecommended name:
    Hexose transporter HXT13
Gene names
Name: HXT13
Synonyms: HXT8
Ordered Locus Names: YEL069C
OrganismSaccharomyces cerevisiae (Baker's yeast) [Complete proteome]
Taxonomic identifier4932 [NCBI]
Taxonomic lineageEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces

Protein attributes

Sequence length564 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is not processed.
Protein existenceEvidence at protein level.

General annotation (Comments)

Function

Probable glucose transporter.

Subcellular location

Membrane; Multi-pass membrane protein.

Sequence similarities

Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. [View classification]

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 564564Hexose transporter HXT13
PRO_0000050402

Regions

Topological domain1 – 5252Cytoplasmic Potential
Transmembrane53 – 73211 Potential
Topological domain74 – 10936Extracellular Potential
Transmembrane110 – 130212 Potential
Topological domain131 – 1366Cytoplasmic Potential
Transmembrane137 – 157213 Potential
Topological domain158 – 16710Extracellular Potential
Transmembrane168 – 188214 Potential
Topological domain189 – 1946Cytoplasmic Potential
Transmembrane195 – 215215 Potential
Topological domain216 – 22914Extracellular Potential
Transmembrane230 – 250216 Potential
Topological domain251 – 33383Cytoplasmic Potential
Transmembrane334 – 350177 Potential
Topological domain351 – 3566Extracellular Potential
Transmembrane357 – 374188 Potential
Topological domain375 – 3817Cytoplasmic Potential
Transmembrane382 – 402219 Potential
Topological domain403 – 42422Extracellular Potential
Transmembrane425 – 4452110 Potential
Topological domain446 – 46217Cytoplasmic Potential
Transmembrane463 – 4832111 Potential
Topological domain4841Extracellular Potential
Transmembrane485 – 5052112 Potential
Topological domain506 – 56459Cytoplasmic Potential

Sequences

Sequence LengthMass (Da)Tools
P39924-1 [UniParc].

Last modified February 1, 1995. Version 1.
Checksum: AEFFFF691718AB44

FASTA56462,734
        10         20         30         40         50         60 
MSSAQSSIDS DGDVRDADIH VAPPVEKEWS DGFDDNEVIN GDNVEPPKRG LIGYLVIYLL 

        70         80         90        100        110        120 
CYPISFGGFL PGWDSGITAG FINMDNFKMN FGSYKHSTGE YYLSNVRMGL LVAMFSIGCA 

       130        140        150        160        170        180 
IGGLIFARLA DTLGRRLAIV IVVLVYMVGA IIQISSNHKW YQYFVGKIIY GLGAGGCSVL 

       190        200        210        220        230        240 
CPMLLSEIAP TDLRGGLVSL YQLNMTFGIF LGYCSVYGTR KYDNTAQWRV PLGLCFLWAL 

       250        260        270        280        290        300 
IIIIGMLLVP ESPRYLIECE RHEEARASIA KINKVSPEDP WVLKQADEIN AGVLAQRELG 

       310        320        330        340        350        360 
EASWKELFSV KTKVLQRLIT GILVQTFLQL TGENYFFFYG TTIFKSVGLT DGFETSIVLG 

       370        380        390        400        410        420 
TVNFFSTIIA VMVVDKIGRR KCLLFGAAGM MACMVIFASI GVKCLYPHGQ DGPSSKGAGN 

       430        440        450        460        470        480 
AMIVFTCFYI FCFATTWAPV AYIVVAESFP SKVKSRAMSI STACNWLWQF LIGFFTPFIT 

       490        500        510        520        530        540 
GSIHFYYGYV FVGCLVAMFL YVFFFLPETI GLSLEEIQLL YEEGIKPWKS ASWVPPSRRG 

       550        560 
ISSEESKTEK KDWKKFLKFS KNSD 

« Hide

References

« Hide 'large scale' references
[1]"The nucleotide sequence of Saccharomyces cerevisiae chromosome V."
Dietrich F.S., Mulligan J.T., Hennessy K.M., Yelton M.A., Allen E., Araujo R., Aviles E., Berno A., Brennan T., Carpenter J., Chen E., Cherry J.M., Chung E., Duncan M., Guzman E., Hartzell G., Hunicke-Smith S., Hyman R.W. expand/collapse author list , Kayser A., Komp C., Lashkari D., Lew H., Lin D., Mosedale D., Nakahara K., Namath A., Norgren R., Oefner P., Oh C., Petel F.X., Roberts D., Sehl P., Schramm S., Shogren T., Smith V., Taylor P., Wei Y., Botstein D., Davis R.W.
Nature 387:78-81(1997) [PubMed: 9169868] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 204511 / S288c / AB972.
[2]"Approaching a complete repository of sequence-verified protein-encoding clones for Saccharomyces cerevisiae."
Hu Y., Rolfs A., Bhullar B., Murthy T.V.S., Zhu C., Berger M.F., Camargo A.A., Kelley F., McCarron S., Jepson D., Richardson A., Raphael J., Moreira D., Taycher E., Zuo D., Mohr S., Kane M.F., Williamson J. expand/collapse author list , Simpson A.J.G., Bulyk M.L., Harlow E., Marsischky G., Kolodner R.D., LaBaer J.
Genome Res. 17:536-543(2007) [PubMed: 17322287] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
Strain: ATCC 204508 / S288c.
[3]"A global topology map of the Saccharomyces cerevisiae membrane proteome."
Kim H., Melen K., Oesterberg M., von Heijne G.
Proc. Natl. Acad. Sci. U.S.A. 103:11142-11147(2006) [PubMed: 16847258] [Abstract]
Cited for: TOPOLOGY [LARGE SCALE ANALYSIS].
+Additional computationally mapped references.

Cross-references

Sequence databases

U18795 Genomic DNA. Translation: AAB65018.1.
AY723801 Genomic DNA. Translation: AAU09718.1.
PIRS50520.
RefSeqNP_010845.1.

3D structure databases

ModBaseSearch...

Protein-protein interaction databases

DIPDIP:3943N.
IntActP39924. 3 interactions.

Genome annotation databases

EnsemblYEL069C; YEL069C; YEL069C; Saccharomyces cerevisiae. [Genome view]
GeneID856640.
KEGGsce:YEL069C.

Organism-specific databases

CYGDYEL069c.
SGDS000000795. HXT13.

Phylogenomic databases

HOGENOMP39924.
OrthoDBEOG95HTDF

Gene expression databases

ArrayExpressP39924.
GenevestigatorP39924.
GermOnlineYEL069C. Saccharomyces cerevisiae.

Family and domain databases

InterProIPR016196. MFS_general_subst_transpt.
IPR005828. Sub_transporter.
IPR003663. Sugar/inositol_transpt.
IPR005829. Sugar_transporter_CS.
[Graphical view]
PfamPF00083. Sugar_tr. 1 hit.
[Graphical view]
PRINTSPR00171. SUGRTRNSPORT.
TIGRFAMsTIGR00879. SP. 1 hit.
PROSITEPS50850. MFS. 1 hit.
PS00216. SUGAR_TRANSPORT_1. 1 hit.
PS00217. SUGAR_TRANSPORT_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Other Resources

NextBio982601.

Entry information

Entry nameHXT13_YEAST
AccessionPrimary (citable) accession number: P39924
Entry history
Integrated into UniProtKB/Swiss-Prot: February 1, 1995
Last sequence update: February 1, 1995
Last modified: November 24, 2009
This is version 72 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation projectFPAP (Fungal Proteome Annotation Project)

Relevant documents

SIMILARITY comments

Index of protein domains and families

Yeast

Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD

Yeast chromosome V

Yeast (Saccharomyces cerevisiae) chromosome V: entries and gene names

Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents