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P39924

- HXT13_YEAST

UniProt

P39924 - HXT13_YEAST

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Protein
Hexose transporter HXT13
Gene
HXT13, HXT8, YEL069C
Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed - Annotation score: 4 out of 5 - Experimental evidence at protein leveli

Functioni

Probable glucose transporter.

GO - Molecular functioni

  1. fructose transmembrane transporter activity Source: SGD
  2. glucose transmembrane transporter activity Source: SGD
  3. mannose transmembrane transporter activity Source: SGD

GO - Biological processi

  1. fructose transport Source: GOC
  2. glucose transport Source: GOC
  3. hexose transport Source: SGD
  4. mannose transport Source: GOC
  5. transmembrane transport Source: SGD
Complete GO annotation...

Keywords - Biological processi

Sugar transport, Transport

Enzyme and pathway databases

BioCyciYEAST:G3O-30184-MONOMER.

Protein family/group databases

TCDBi2.A.1.1.110. the major facilitator superfamily (mfs).

Names & Taxonomyi

Protein namesi
Recommended name:
Hexose transporter HXT13
Gene namesi
Name:HXT13
Synonyms:HXT8
Ordered Locus Names:YEL069C
OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Taxonomic identifieri559292 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
ProteomesiUP000002311: Chromosome V

Organism-specific databases

CYGDiYEL069c.
SGDiS000000795. HXT13.

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Topological domaini1 – 5252Cytoplasmic Reviewed prediction
Add
BLAST
Transmembranei53 – 7321Helical; Name=1; Reviewed prediction
Add
BLAST
Topological domaini74 – 10936Extracellular Reviewed prediction
Add
BLAST
Transmembranei110 – 13021Helical; Name=2; Reviewed prediction
Add
BLAST
Topological domaini131 – 1366Cytoplasmic Reviewed prediction
Transmembranei137 – 15721Helical; Name=3; Reviewed prediction
Add
BLAST
Topological domaini158 – 16710Extracellular Reviewed prediction
Transmembranei168 – 18821Helical; Name=4; Reviewed prediction
Add
BLAST
Topological domaini189 – 1946Cytoplasmic Reviewed prediction
Transmembranei195 – 21521Helical; Name=5; Reviewed prediction
Add
BLAST
Topological domaini216 – 22914Extracellular Reviewed prediction
Add
BLAST
Transmembranei230 – 25021Helical; Name=6; Reviewed prediction
Add
BLAST
Topological domaini251 – 33383Cytoplasmic Reviewed prediction
Add
BLAST
Transmembranei334 – 35017Helical; Name=7; Reviewed prediction
Add
BLAST
Topological domaini351 – 3566Extracellular Reviewed prediction
Transmembranei357 – 37418Helical; Name=8; Reviewed prediction
Add
BLAST
Topological domaini375 – 3817Cytoplasmic Reviewed prediction
Transmembranei382 – 40221Helical; Name=9; Reviewed prediction
Add
BLAST
Topological domaini403 – 42422Extracellular Reviewed prediction
Add
BLAST
Transmembranei425 – 44521Helical; Name=10; Reviewed prediction
Add
BLAST
Topological domaini446 – 46217Cytoplasmic Reviewed prediction
Add
BLAST
Transmembranei463 – 48321Helical; Name=11; Reviewed prediction
Add
BLAST
Topological domaini484 – 4841Extracellular Reviewed prediction
Transmembranei485 – 50521Helical; Name=12; Reviewed prediction
Add
BLAST
Topological domaini506 – 56459Cytoplasmic Reviewed prediction
Add
BLAST

GO - Cellular componenti

  1. integral component of membrane Source: UniProtKB-KW
  2. plasma membrane Source: SGD
Complete GO annotation...

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 564564Hexose transporter HXT13
PRO_0000050402Add
BLAST

Expressioni

Gene expression databases

GenevestigatoriP39924.

Interactioni

Protein-protein interaction databases

DIPiDIP-3943N.
MINTiMINT-530973.
STRINGi4932.YEL069C.

Structurei

3D structure databases

ProteinModelPortaliP39924.
SMRiP39924. Positions 57-522.

Family & Domainsi

Sequence similaritiesi

Keywords - Domaini

Repeat, Transmembrane, Transmembrane helix

Phylogenomic databases

GeneTreeiENSGT00720000108754.
HOGENOMiHOG000202870.
KOiK08139.
OrthoDBiEOG73JM4H.

Family and domain databases

InterProiIPR020846. MFS_dom.
IPR016196. MFS_dom_general_subst_transpt.
IPR005828. Sub_transporter.
IPR003663. Sugar/inositol_transpt.
IPR005829. Sugar_transporter_CS.
[Graphical view]
PfamiPF00083. Sugar_tr. 1 hit.
[Graphical view]
PRINTSiPR00171. SUGRTRNSPORT.
SUPFAMiSSF103473. SSF103473. 1 hit.
TIGRFAMsiTIGR00879. SP. 1 hit.
PROSITEiPS50850. MFS. 1 hit.
PS00216. SUGAR_TRANSPORT_1. 1 hit.
PS00217. SUGAR_TRANSPORT_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P39924-1 [UniParc]FASTAAdd to Basket

« Hide

MSSAQSSIDS DGDVRDADIH VAPPVEKEWS DGFDDNEVIN GDNVEPPKRG    50
LIGYLVIYLL CYPISFGGFL PGWDSGITAG FINMDNFKMN FGSYKHSTGE 100
YYLSNVRMGL LVAMFSIGCA IGGLIFARLA DTLGRRLAIV IVVLVYMVGA 150
IIQISSNHKW YQYFVGKIIY GLGAGGCSVL CPMLLSEIAP TDLRGGLVSL 200
YQLNMTFGIF LGYCSVYGTR KYDNTAQWRV PLGLCFLWAL IIIIGMLLVP 250
ESPRYLIECE RHEEARASIA KINKVSPEDP WVLKQADEIN AGVLAQRELG 300
EASWKELFSV KTKVLQRLIT GILVQTFLQL TGENYFFFYG TTIFKSVGLT 350
DGFETSIVLG TVNFFSTIIA VMVVDKIGRR KCLLFGAAGM MACMVIFASI 400
GVKCLYPHGQ DGPSSKGAGN AMIVFTCFYI FCFATTWAPV AYIVVAESFP 450
SKVKSRAMSI STACNWLWQF LIGFFTPFIT GSIHFYYGYV FVGCLVAMFL 500
YVFFFLPETI GLSLEEIQLL YEEGIKPWKS ASWVPPSRRG ISSEESKTEK 550
KDWKKFLKFS KNSD 564
Length:564
Mass (Da):62,734
Last modified:February 1, 1995 - v1
Checksum:iAEFFFF691718AB44
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
U18795 Genomic DNA. Translation: AAB65018.1.
AY723801 Genomic DNA. Translation: AAU09718.1.
BK006939 Genomic DNA. Translation: DAA07586.1.
PIRiS50520.
RefSeqiNP_010845.1. NM_001178884.1.

Genome annotation databases

EnsemblFungiiYEL069C; YEL069C; YEL069C.
GeneIDi856640.
KEGGisce:YEL069C.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
U18795 Genomic DNA. Translation: AAB65018.1 .
AY723801 Genomic DNA. Translation: AAU09718.1 .
BK006939 Genomic DNA. Translation: DAA07586.1 .
PIRi S50520.
RefSeqi NP_010845.1. NM_001178884.1.

3D structure databases

ProteinModelPortali P39924.
SMRi P39924. Positions 57-522.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

DIPi DIP-3943N.
MINTi MINT-530973.
STRINGi 4932.YEL069C.

Protein family/group databases

TCDBi 2.A.1.1.110. the major facilitator superfamily (mfs).

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblFungii YEL069C ; YEL069C ; YEL069C .
GeneIDi 856640.
KEGGi sce:YEL069C.

Organism-specific databases

CYGDi YEL069c.
SGDi S000000795. HXT13.

Phylogenomic databases

GeneTreei ENSGT00720000108754.
HOGENOMi HOG000202870.
KOi K08139.
OrthoDBi EOG73JM4H.

Enzyme and pathway databases

BioCyci YEAST:G3O-30184-MONOMER.

Miscellaneous databases

NextBioi 982601.

Gene expression databases

Genevestigatori P39924.

Family and domain databases

InterProi IPR020846. MFS_dom.
IPR016196. MFS_dom_general_subst_transpt.
IPR005828. Sub_transporter.
IPR003663. Sugar/inositol_transpt.
IPR005829. Sugar_transporter_CS.
[Graphical view ]
Pfami PF00083. Sugar_tr. 1 hit.
[Graphical view ]
PRINTSi PR00171. SUGRTRNSPORT.
SUPFAMi SSF103473. SSF103473. 1 hit.
TIGRFAMsi TIGR00879. SP. 1 hit.
PROSITEi PS50850. MFS. 1 hit.
PS00216. SUGAR_TRANSPORT_1. 1 hit.
PS00217. SUGAR_TRANSPORT_2. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 204508 / S288c.
  2. Cited for: GENOME REANNOTATION.
    Strain: ATCC 204508 / S288c.
  3. Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
    Strain: ATCC 204508 / S288c.
  4. "A global topology map of the Saccharomyces cerevisiae membrane proteome."
    Kim H., Melen K., Oesterberg M., von Heijne G.
    Proc. Natl. Acad. Sci. U.S.A. 103:11142-11147(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: TOPOLOGY [LARGE SCALE ANALYSIS].
    Strain: ATCC 208353 / W303-1A.

Entry informationi

Entry nameiHXT13_YEAST
AccessioniPrimary (citable) accession number: P39924
Secondary accession number(s): D3DLI2
Entry historyi
Integrated into UniProtKB/Swiss-Prot: February 1, 1995
Last sequence update: February 1, 1995
Last modified: May 14, 2014
This is version 109 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Yeast
    Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD
  3. Yeast chromosome V
    Yeast (Saccharomyces cerevisiae) chromosome V: entries and gene names

External Data

Dasty 3

Similar proteinsi