P39902 (SPRT_ECOLI) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Protein SprT

Gene names

Name:	sprT
Synonyms:	yggI
Ordered Locus Names:	b2944, JW2911

Organism

Escherichia coli (strain K12) [Reference proteome] [HAMAP]

Taxonomic identifier

83333 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Escherichia › Escherichia coli

Protein attributes

Sequence length	165 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Involved in bolA gene expression at the stationary phase. HAMAP-Rule MF_00746
Cofactor	Binds 1 zinc ion Potential.
Subcellular location	Cytoplasm Potential HAMAP-Rule MF_00746.
Sequence similarities	Belongs to the SprT family. Contains 1 SprT-like domain.

Ontologies

Keywords
Cellular component	Cytoplasm
Ligand	Metal-binding Zinc
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Cellular_component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular_function	zinc ion binding Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 165	165	Protein SprT HAMAP-Rule MF_00746		PRO_0000213266
Regions
	Domain	20 – 163	144	SprT-like
Sites
	Active site	79	1	Potential
	Metal binding	78	1	Zinc Potential
	Metal binding	82	1	Zinc Potential

Sequences

	Sequence		Length	Mass (Da)
	P39902 [UniParc]. Last modified February 1, 1995. Version 1. Checksum: F5E4A3992DD091B4	FASTA	165	19,348
	10 20 30 40 50 60 MKTSRLPIAI QQAVMRRLRE KLAQANLKLG RNYPEPKLSY TQRGTSAGTA WLESYEIRLN 70 80 90 100 110 120 PVLLLENSEA FIEEVVPHEL AHLLVWKHFG RVAPHGKEWK WMMENVLGVP ARRTHQFELQ 130 140 150 160 SVRRNTFPYR CKCQEHQLTV RRHNRVVRGE AVYRCVHCGE QLVAK

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"A newly identified gene sprT which is involved in bolA gene expression." Utsumi R., Suzuki T. Submitted (FEB-1996) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
[2]	Roberts P.E. Thesis (1992), University of Cambridge, United Kingdom Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
[3]	"The complete genome sequence of Escherichia coli K-12." Blattner F.R., Plunkett G. III, Bloch C.A., Perna N.T., Burland V., Riley M., Collado-Vides J., Glasner J.D., Rode C.K., Mayhew G.F., Gregor J., Davis N.W., Kirkpatrick H.A., Goeden M.A., Rose D.J., Mau B., Shao Y. Science 277:1453-1474(1997) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: K12 / MG1655 / ATCC 47076.
[4]	"Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110." Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S., Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T. Mol. Syst. Biol. 2:E1-E5(2006) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: K12 / W3110 / ATCC 27325 / DSM 5911.
[5]	"Location of the endA gene coding for endonuclease I on the physical map of the Escherichia coli K-12 chromosome." Jekel M., Wackernagel W. J. Bacteriol. 176:1550-1551(1994) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 70-165. Strain: K12 / W3110 / ATCC 27325 / DSM 5911.
[6]	"Intrinsic and extrinsic approaches for detecting genes in a bacterial genome." Borodovsky M., Rudd K.E., Koonin E.V. Nucleic Acids Res. 22:4756-4767(1994) [PubMed] [Europe PMC] [Abstract] Cited for: IDENTIFICATION.

Cross-references

Sequence databases
EMBL GenBank DDBJ	D83644 Genomic DNA. Translation: BAA12021.1. U28377 Genomic DNA. Translation: AAA69111.1. U00096 Genomic DNA. Translation: AAC75981.1. AP009048 Genomic DNA. Translation: BAE77007.1. X65169 Genomic DNA. No translation available.
PIR	G65079.
RefSeq	NP_417419.1. NC_000913.2. YP_491143.1. NC_007779.1.
3D structure databases
ProteinModelPortal	P39902.
ModBase	Search...
Protein-protein interaction databases
IntAct	P39902. 7 interactions.
STRING	511145.b2944.
Proteomic databases
PaxDb	P39902.
PRIDE	P39902.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	AAC75981; AAC75981; b2944. BAE77007; BAE77007; BAE77007.
GeneID	12930537. 947443.
KEGG	ecj:Y75_p2874. eco:b2944.
PATRIC	32121298. VBIEscCol129921_3037.
Organism-specific databases
EchoBASE	EB2043.
EcoGene	EG12122. sprT.
Phylogenomic databases
eggNOG	COG3091.
HOGENOM	HOG000281171.
KO	K02742.
OMA	QLIMRGV.
ProtClustDB	PRK04860.
Enzyme and pathway databases
BioCyc	EcoCyc:EG12122-MONOMER. ECOL316407:JW2911-MONOMER.
Gene expression databases
Genevestigator	P39902.
Family and domain databases
HAMAP	MF_00746. SprT.
InterPro	IPR006640. SprT-like_domain. IPR023483. Uncharacterised_SprT. [Graphical view]
Pfam	PF10263. SprT-like. 1 hit. [Graphical view]
SMART	SM00731. SprT. 1 hit. [Graphical view]
PROSITE	PS00142. ZINC_PROTEASE. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

SPRT_ECOLI

Accession

Primary (citable) accession number: P39902
Secondary accession number(s): Q2M9P9

Entry history

Integrated into UniProtKB/Swiss-Prot:	February 1, 1995
Last sequence update:	February 1, 1995
Last modified:	May 1, 2013
This is version 93 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program