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P39890 (TCMI_STRGA) Reviewed, UniProtKB/Swiss-Prot

Last modified October 16, 2013. Version 54. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Tetracenomycin polyketide synthesis protein TcmI
Gene names
Name:tcmI
OrganismStreptomyces glaucescens
Taxonomic identifier1907 [NCBI]
Taxonomic lineageBacteriaActinobacteriaActinobacteridaeActinomycetalesStreptomycineaeStreptomycetaceaeStreptomyces

Protein attributes

Sequence length109 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

General annotation (Comments)

Function

Required for conversion of tetracenomycin F2 to tetracenomycin D3.

Pathway

Antibiotic biosynthesis; tetracenomycin C biosynthesis.

Ontologies

Keywords
   Biological processAntibiotic biosynthesis
   Technical term3D-structure
Gene Ontology (GO)
   Biological_processantibiotic biosynthetic process

Inferred from electronic annotation. Source: UniProtKB-KW

polyketide biosynthetic process

Inferred from electronic annotation. Source: InterPro

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 109109Tetracenomycin polyketide synthesis protein TcmI
PRO_0000072454

Secondary structure

..................... 109
Helix Strand Turn

Details...

Sequences

Sequence LengthMass (Da)Tools
P39890 [UniParc].

Last modified February 1, 1995. Version 1.
Checksum: 1F9E3EC9E1B90593

FASTA10912,861
        10         20         30         40         50         60 
MAYRALMVLR MDPADAEHVA AAFAEHDTTE LPLEIGVRRR VLFRFHDLYM HLIEADDDIM 

        70         80         90        100 
ERLYQARSHP LFQEVNERVG QYLTPYAQDW EELKDSKAEV FYSWTAPDS 

« Hide

References

[1]"Sequence and transcriptional analysis of the Streptomyces glaucescens tcmAR tetracenomycin C resistance and repressor gene loci."
Guilfoile P.G., Hutchinson C.R.
J. Bacteriol. 174:3651-3658(1992) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
Strain: DSM 40716 / ETH 22794 / GLA.0.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
M80674 Genomic DNA. Translation: AAA67513.1.
PIRB53291.

3D structure databases

PDBe
RCSB PDB
PDBj
EntryMethodResolution (Å)ChainPositionsPDBsum
1TUWX-ray1.90A1-109[»]
ProteinModelPortalP39890.
SMRP39890. Positions 2-107.
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Enzyme and pathway databases

UniPathwayUPA00174.

Family and domain databases

Gene3D3.30.70.1090. 1 hit.
InterProIPR011008. Dimeric_a/b-barrel.
IPR006765. Polyketide_synth_cyclase.
[Graphical view]
PfamPF04673. Cyclase_polyket. 1 hit.
[Graphical view]
ProDomPD012644. Polyketide_synth_cyclase. 1 hit.
[Graphical view] [Entries sharing at least one domain]
SUPFAMSSF54909. SSF54909. 1 hit.
ProtoNetSearch...

Other

EvolutionaryTraceP39890.

Entry information

Entry nameTCMI_STRGA
AccessionPrimary (citable) accession number: P39890
Entry history
Integrated into UniProtKB/Swiss-Prot: February 1, 1995
Last sequence update: February 1, 1995
Last modified: October 16, 2013
This is version 54 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

PDB cross-references

Index of Protein Data Bank (PDB) cross-references

PATHWAY comments

Index of metabolic and biosynthesis pathways