P39880 (CUX1_HUMAN) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Homeobox protein cut-like 1

Alternative name(s):
CCAAT displacement protein
Short name=CDP
Homeobox protein cux-1

Gene names

Name:	CUX1
Synonyms:	CUTL1

Organism

Homo sapiens (Human) [Reference proteome]

Taxonomic identifier

9606 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Euarchontoglires › Primates › Haplorrhini › Simiiformes › Catarrhini › Hominoidea › Hominidae › Homininae › Homo

Protein attributes

Sequence length	1505 AA.
Sequence status	Complete.
Protein existence	Evidence at protein level

General annotation (Comments)

Function	Probably has a broad role in mammalian development as a repressor of developmentally regulated gene expression. May act by preventing binding of positively-activing CCAAT factors to promoters. Component of nf-munr repressor; binds to the matrix attachment regions (MARs) (5' and 3') of the immunoglobulin heavy chain enhancer. Represses T-cell receptor (TCR) beta enhancer function by binding to MARbeta, an ATC-rich DNA sequence located upstream of the TCR beta enhancer By similarity.
Subunit structure	Interacts with BANP By similarity.
Subcellular location	Nucleus.
Miscellaneous	Asn-1290 may participate in regulating DNA-binding activity by promoting homo- and heterodimerization.
Sequence similarities	Belongs to the CUT homeobox family. Contains 3 CUT DNA-binding domains. Contains 1 homeobox DNA-binding domain.

Ontologies

Keywords
Biological process	Transcription Transcription regulation
Cellular component	Nucleus
Coding sequence diversity	Alternative splicing
Domain	Coiled coil Homeobox Repeat
Ligand	DNA-binding
Molecular function	Developmental protein Repressor
PTM	Phosphoprotein
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	auditory receptor cell differentiation Inferred from electronic annotation. Source: Compara lung development Inferred from electronic annotation. Source: Compara multicellular organismal development Traceable author statement Ref.1. Source: ProtInc negative regulation of transcription from RNA polymerase II promoter Traceable author statement Ref.1. Source: ProtInc retrograde transport, vesicle recycling within Golgi Inferred from electronic annotation. Source: Compara transcription, DNA-dependent Inferred from electronic annotation. Source: UniProtKB-KW
Cellular_component	Golgi membrane Inferred from electronic annotation. Source: Compara cytosol Traceable author statement. Source: Reactome nucleus Inferred from direct assay. Source: HPA
Molecular_function	chromatin binding Inferred from electronic annotation. Source: Compara sequence-specific DNA binding Inferred from electronic annotation. Source: InterPro sequence-specific DNA binding transcription factor activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Alternative products

This entry describes 11 isoforms produced by alternative splicing. [Align] [Select]

Note: Additional isoforms seem to exist.

Isoform 1 (identifier: P39880-1)

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

Isoform 2 (identifier: P39880-2)

The sequence of this isoform differs from the canonical sequence as follows:
     632-653: Missing.

Isoform 3 (identifier: P39880-3)

The sequence of this isoform differs from the canonical sequence as follows:
     1-10: MLCVAGARLK → MAANVGSMFQYWKRFDLQQLQ

Note: No experimental confirmation available.

Isoform 5 (identifier: P39880-4)

The sequence of this isoform differs from the canonical sequence as follows:
     408-509: Missing.

Isoform 6 (identifier: P39880-5)

The sequence of this isoform differs from the canonical sequence as follows:
     632-687: Missing.

Isoform 7 (identifier: P39880-6)

The sequence of this isoform differs from the canonical sequence as follows:
     408-509: Missing.
     632-687: Missing.

Isoform 11 (identifier: P39880-9)

The sequence of this isoform differs from the canonical sequence as follows:
     1-10: MLCVAGARLK → MAANVGSMFQYWKRFDLQQLQ
     90-135: Missing.
     409-667: SARRKGKDQP...TRIRASETGS → RCAELQVRIT...NGAAAGDLWQ
     668-1505: Missing.

Note: No experimental confirmation available.

Isoform 4 (identifier: Q13948-1)

Also known as: CASP;

The sequence of this isoform can be found in the external entry Q13948.
Isoforms of the same protein are often annotated in two different entries if their sequences differ significantly.

Isoform 8 (identifier: Q13948-2)

The sequence of this isoform can be found in the external entry Q13948.
Isoforms of the same protein are often annotated in two different entries if their sequences differ significantly.

Note: No experimental confirmation available.

Isoform 9 (identifier: Q13948-9)

The sequence of this isoform can be found in the external entry Q13948.
Isoforms of the same protein are often annotated in two different entries if their sequences differ significantly.

Note: No experimental confirmation available.

Isoform 10 (identifier: Q13948-10)

The sequence of this isoform can be found in the external entry Q13948.
Isoforms of the same protein are often annotated in two different entries if their sequences differ significantly.

Note: No experimental confirmation available.

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 1505	1505	Homeobox protein cut-like 1		PRO_0000202393
Regions
	DNA binding	542 – 629	88	CUT 1
	DNA binding	934 – 1021	88	CUT 2
	DNA binding	1117 – 1204	88	CUT 3
	DNA binding	1244 – 1303	60	Homeobox
	Coiled coil	7 – 363	357	Potential
	Coiled coil	669 – 725	57	Potential
Amino acid modifications
	Modified residue	763	1	Phosphoserine Ref.10
Natural variations
	Alternative sequence	1 – 10	10	MLCVAGARLK → MAANVGSMFQYWKRFDLQQL Q in isoform 3 and isoform 11.		VSP_015747
	Alternative sequence	90 – 135	46	Missing in isoform 11.		VSP_045924
	Alternative sequence	408 – 509	102	Missing in isoform 5 and isoform 7.		VSP_017358
	Alternative sequence	409 – 667	259	SARRK…SETGS → RCAELQVRITEAVATATEQR ELIARLEQDLSIIQSIQRPD AEGAAEHRLEKIPEPIKEAT ALFYGPAAPASGALPEGQVD SLLSIISSQRERFRARNQEL EAENRLAQHTLQALQSELDS LRADNIKLFEKIKFLQSYPG RGSGSDDTELRYSSQYEERL DPFSSFSKRERQRKYLSLSP WDKATLSMGRLVLSNKMART IGFFYTLFLHCLVFLVLYKL AWSESMERDCATFCAKKFAD HLHKFHENDNGAAAGDLWQ in isoform 11.		VSP_045925
	Alternative sequence	632 – 687	56	Missing in isoform 6 and isoform 7.		VSP_017359
	Alternative sequence	632 – 653	22	Missing in isoform 2.		VSP_002310
	Alternative sequence	668 – 1505	838	Missing in isoform 11.		VSP_045926
Experimental info
	Sequence conflict	5	1	A → R in M74099. Ref.1
	Sequence conflict	145	1	K → I in BAG53691. Ref.2
	Sequence conflict	260	1	A → V in BAG53691. Ref.2
	Sequence conflict	704 – 705	2	DA → EP in M74099. Ref.1
	Sequence conflict	844	1	E → R in M74099. Ref.1
	Sequence conflict	1436	1	S → T in M74099. Ref.1

Sequences

	Sequence		Length	Mass (Da)
	Isoform 1 [UniParc]. Last modified May 18, 2010. Version 3. Checksum: 0F9027E5B8F08D95	FASTA	1,505	164,187
	10 20 30 40 50 60 MLCVAGARLK RELDATATVL ANRQDESEQS RKRLIEQSRE FKKNTPEDLR KQVAPLLKSF 70 80 90 100 110 120 QGEIDALSKR SKEAEAAFLN VYKRLIDVPD PVPALDLGQQ LQLKVQRLHD IETENQKLRE 130 140 150 160 170 180 TLEEYNKEFA EVKNQEVTIK ALKEKIREYE QTLKNQAETI ALEKEQKLQN DFAEKERKLQ 190 200 210 220 230 240 ETQMSTTSKL EEAEHKVQSL QTALEKTRTE LFDLKTKYDE ETTAKADEIE MIMTDLERAN 250 260 270 280 290 300 QRAEVAQREA ETLREQLSSA NHSLQLASQI QKAPDVEQAI EVLTRSSLEV ELAAKEREIA 310 320 330 340 350 360 QLVEDVQRLQ ASLTKLRENS ASQISQLEQQ LSAKNSTLKQ LEEKLKGQAD YEEVKKELNI 370 380 390 400 410 420 LKSMEFAPSE GAGTQDAAKP LEVLLLEKNR SLQSENAALR ISNSDLSGSA RRKGKDQPES 430 440 450 460 470 480 RRPGSLPAPP PSQLPRNPGE QASNTNGTHQ FSPAGLSQDF FSSSLASPSL PLASTGKFAL 490 500 510 520 530 540 NSLLQRQLMQ SFYSKAMQEA GSTSMIFSTG PYSTNSISSQ SPLQQSPDVN GMAPSPSQSE 550 560 570 580 590 600 SAGSVSEGEE MDTAEIARQV KEQLIKHNIG QRIFGHYVLG LSQGSVSEIL ARPKPWNKLT 610 620 630 640 650 660 VRGKEPFHKM KQFLSDEQNI LALRSIQGRQ RENPGQSLNR LFQEVPKRRN GSEGNITTRI 670 680 690 700 710 720 RASETGSDEA IKSILEQAKR ELQVQKTAEP AQPSSASGSG NSDDAIRSIL QQARREMEAQ 730 740 750 760 770 780 QAALDPALKQ APLSQSDITI LTPKLLSTSP MPTVSSYPPL AISLKKPSAA PEAGASALPN 790 800 810 820 830 840 PPALKKEAQD APGLDPQGAA DCAQGVLRQV KNEVGRSGAW KDHWWSAVQP ERRNAASSEE 850 860 870 880 890 900 AKAEETGGGK EKGSGGSGGG SQPRAERSQL QGPSSSEYWK EWPSAESPYS QSSELSLTGA 910 920 930 940 950 960 SRSETPQNSP LPSSPIVPMS KPTKPSVPPL TPEQYEVYMY QEVDTIELTR QVKEKLAKNG 970 980 990 1000 1010 1020 ICQRIFGEKV LGLSQGSVSD MLSRPKPWSK LTQKGREPFI RMQLWLNGEL GQGVLPVQGQ 1030 1040 1050 1060 1070 1080 QQGPVLHSVT SLQDPLQQGC VSSESTPKTS ASCSPAPESP MSSSESVKSL TELVQQPCPP 1090 1100 1110 1120 1130 1140 IEASKDSKPP EPSDPPASDS QPTTPLPLSG HSALSIQELV AMSPELDTYG ITKRVKEVLT 1150 1160 1170 1180 1190 1200 DNNLGQRLFG ETILGLTQGS VSDLLARPKP WHKLSLKGRE PFVRMQLWLN DPNNVEKLMD 1210 1220 1230 1240 1250 1260 MKRMEKKAYM KRRHSSVSDS QPCEPPSVGT EYSQGASPQP QHQLKKPRVV LAPEEKEALK 1270 1280 1290 1300 1310 1320 RAYQQKPYPS PKTIEDLATQ LNLKTSTVIN WFHNYRSRIR RELFIEEIQA GSQGQAGASD 1330 1340 1350 1360 1370 1380 SPSARSGRAA PSSEGDSCDG VEATEGPGSA DTEEPKSQGE AEREEVPRPA EQTEPPPSGT 1390 1400 1410 1420 1430 1440 PGPDDARDDD HEGGPVEGPG PLPSPASATA TAAPAAPEDA ATSAAAAPGE GPAAPSSAPP 1450 1460 1470 1480 1490 1500 PSNSSSSSAP RRPSSLQSLF GLPEAAGARD SRDNPLRKKK AANLNSIIHR LEKAASREEP IEWEF
	Isoform 2 [UniParc]. Checksum: 369D44022E3FF3D7	FASTA	1,483	161,650
	10 20 30 40 50 60 MLCVAGARLK RELDATATVL ANRQDESEQS RKRLIEQSRE FKKNTPEDLR KQVAPLLKSF 70 80 90 100 110 120 QGEIDALSKR SKEAEAAFLN VYKRLIDVPD PVPALDLGQQ LQLKVQRLHD IETENQKLRE 130 140 150 160 170 180 TLEEYNKEFA EVKNQEVTIK ALKEKIREYE QTLKNQAETI ALEKEQKLQN DFAEKERKLQ 190 200 210 220 230 240 ETQMSTTSKL EEAEHKVQSL QTALEKTRTE LFDLKTKYDE ETTAKADEIE MIMTDLERAN 250 260 270 280 290 300 QRAEVAQREA ETLREQLSSA NHSLQLASQI QKAPDVEQAI EVLTRSSLEV ELAAKEREIA 310 320 330 340 350 360 QLVEDVQRLQ ASLTKLRENS ASQISQLEQQ LSAKNSTLKQ LEEKLKGQAD YEEVKKELNI 370 380 390 400 410 420 LKSMEFAPSE GAGTQDAAKP LEVLLLEKNR SLQSENAALR ISNSDLSGSA RRKGKDQPES 430 440 450 460 470 480 RRPGSLPAPP PSQLPRNPGE QASNTNGTHQ FSPAGLSQDF FSSSLASPSL PLASTGKFAL 490 500 510 520 530 540 NSLLQRQLMQ SFYSKAMQEA GSTSMIFSTG PYSTNSISSQ SPLQQSPDVN GMAPSPSQSE 550 560 570 580 590 600 SAGSVSEGEE MDTAEIARQV KEQLIKHNIG QRIFGHYVLG LSQGSVSEIL ARPKPWNKLT 610 620 630 640 650 660 VRGKEPFHKM KQFLSDEQNI LALRSIQGRQ RGNITTRIRA SETGSDEAIK SILEQAKREL 670 680 690 700 710 720 QVQKTAEPAQ PSSASGSGNS DDAIRSILQQ ARREMEAQQA ALDPALKQAP LSQSDITILT 730 740 750 760 770 780 PKLLSTSPMP TVSSYPPLAI SLKKPSAAPE AGASALPNPP ALKKEAQDAP GLDPQGAADC 790 800 810 820 830 840 AQGVLRQVKN EVGRSGAWKD HWWSAVQPER RNAASSEEAK AEETGGGKEK GSGGSGGGSQ 850 860 870 880 890 900 PRAERSQLQG PSSSEYWKEW PSAESPYSQS SELSLTGASR SETPQNSPLP SSPIVPMSKP 910 920 930 940 950 960 TKPSVPPLTP EQYEVYMYQE VDTIELTRQV KEKLAKNGIC QRIFGEKVLG LSQGSVSDML 970 980 990 1000 1010 1020 SRPKPWSKLT QKGREPFIRM QLWLNGELGQ GVLPVQGQQQ GPVLHSVTSL QDPLQQGCVS 1030 1040 1050 1060 1070 1080 SESTPKTSAS CSPAPESPMS SSESVKSLTE LVQQPCPPIE ASKDSKPPEP SDPPASDSQP 1090 1100 1110 1120 1130 1140 TTPLPLSGHS ALSIQELVAM SPELDTYGIT KRVKEVLTDN NLGQRLFGET ILGLTQGSVS 1150 1160 1170 1180 1190 1200 DLLARPKPWH KLSLKGREPF VRMQLWLNDP NNVEKLMDMK RMEKKAYMKR RHSSVSDSQP 1210 1220 1230 1240 1250 1260 CEPPSVGTEY SQGASPQPQH QLKKPRVVLA PEEKEALKRA YQQKPYPSPK TIEDLATQLN 1270 1280 1290 1300 1310 1320 LKTSTVINWF HNYRSRIRRE LFIEEIQAGS QGQAGASDSP SARSGRAAPS SEGDSCDGVE 1330 1340 1350 1360 1370 1380 ATEGPGSADT EEPKSQGEAE REEVPRPAEQ TEPPPSGTPG PDDARDDDHE GGPVEGPGPL 1390 1400 1410 1420 1430 1440 PSPASATATA APAAPEDAAT SAAAAPGEGP AAPSSAPPPS NSSSSSAPRR PSSLQSLFGL 1450 1460 1470 1480 PEAAGARDSR DNPLRKKKAA NLNSIIHRLE KAASREEPIE WEF
	Isoform 3 [UniParc]. Checksum: 13E5E97E8569C5AA	FASTA	1,516	165,688
	10 20 30 40 50 60 MAANVGSMFQ YWKRFDLQQL QRELDATATV LANRQDESEQ SRKRLIEQSR EFKKNTPEDL 70 80 90 100 110 120 RKQVAPLLKS FQGEIDALSK RSKEAEAAFL NVYKRLIDVP DPVPALDLGQ QLQLKVQRLH 130 140 150 160 170 180 DIETENQKLR ETLEEYNKEF AEVKNQEVTI KALKEKIREY EQTLKNQAET IALEKEQKLQ 190 200 210 220 230 240 NDFAEKERKL QETQMSTTSK LEEAEHKVQS LQTALEKTRT ELFDLKTKYD EETTAKADEI 250 260 270 280 290 300 EMIMTDLERA NQRAEVAQRE AETLREQLSS ANHSLQLASQ IQKAPDVEQA IEVLTRSSLE 310 320 330 340 350 360 VELAAKEREI AQLVEDVQRL QASLTKLREN SASQISQLEQ QLSAKNSTLK QLEEKLKGQA 370 380 390 400 410 420 DYEEVKKELN ILKSMEFAPS EGAGTQDAAK PLEVLLLEKN RSLQSENAAL RISNSDLSGS 430 440 450 460 470 480 ARRKGKDQPE SRRPGSLPAP PPSQLPRNPG EQASNTNGTH QFSPAGLSQD FFSSSLASPS 490 500 510 520 530 540 LPLASTGKFA LNSLLQRQLM QSFYSKAMQE AGSTSMIFST GPYSTNSISS QSPLQQSPDV 550 560 570 580 590 600 NGMAPSPSQS ESAGSVSEGE EMDTAEIARQ VKEQLIKHNI GQRIFGHYVL GLSQGSVSEI 610 620 630 640 650 660 LARPKPWNKL TVRGKEPFHK MKQFLSDEQN ILALRSIQGR QRENPGQSLN RLFQEVPKRR 670 680 690 700 710 720 NGSEGNITTR IRASETGSDE AIKSILEQAK RELQVQKTAE PAQPSSASGS GNSDDAIRSI 730 740 750 760 770 780 LQQARREMEA QQAALDPALK QAPLSQSDIT ILTPKLLSTS PMPTVSSYPP LAISLKKPSA 790 800 810 820 830 840 APEAGASALP NPPALKKEAQ DAPGLDPQGA ADCAQGVLRQ VKNEVGRSGA WKDHWWSAVQ 850 860 870 880 890 900 PERRNAASSE EAKAEETGGG KEKGSGGSGG GSQPRAERSQ LQGPSSSEYW KEWPSAESPY 910 920 930 940 950 960 SQSSELSLTG ASRSETPQNS PLPSSPIVPM SKPTKPSVPP LTPEQYEVYM YQEVDTIELT 970 980 990 1000 1010 1020 RQVKEKLAKN GICQRIFGEK VLGLSQGSVS DMLSRPKPWS KLTQKGREPF IRMQLWLNGE 1030 1040 1050 1060 1070 1080 LGQGVLPVQG QQQGPVLHSV TSLQDPLQQG CVSSESTPKT SASCSPAPES PMSSSESVKS 1090 1100 1110 1120 1130 1140 LTELVQQPCP PIEASKDSKP PEPSDPPASD SQPTTPLPLS GHSALSIQEL VAMSPELDTY 1150 1160 1170 1180 1190 1200 GITKRVKEVL TDNNLGQRLF GETILGLTQG SVSDLLARPK PWHKLSLKGR EPFVRMQLWL 1210 1220 1230 1240 1250 1260 NDPNNVEKLM DMKRMEKKAY MKRRHSSVSD SQPCEPPSVG TEYSQGASPQ PQHQLKKPRV 1270 1280 1290 1300 1310 1320 VLAPEEKEAL KRAYQQKPYP SPKTIEDLAT QLNLKTSTVI NWFHNYRSRI RRELFIEEIQ 1330 1340 1350 1360 1370 1380 AGSQGQAGAS DSPSARSGRA APSSEGDSCD GVEATEGPGS ADTEEPKSQG EAEREEVPRP 1390 1400 1410 1420 1430 1440 AEQTEPPPSG TPGPDDARDD DHEGGPVEGP GPLPSPASAT ATAAPAAPED AATSAAAAPG 1450 1460 1470 1480 1490 1500 EGPAAPSSAP PPSNSSSSSA PRRPSSLQSL FGLPEAAGAR DSRDNPLRKK KAANLNSIIH 1510 RLEKAASREE PIEWEF
	Isoform 5 [UniParc]. Checksum: B10F9B5E864C9D8F	FASTA	1,403	153,364
	10 20 30 40 50 60 MLCVAGARLK RELDATATVL ANRQDESEQS RKRLIEQSRE FKKNTPEDLR KQVAPLLKSF 70 80 90 100 110 120 QGEIDALSKR SKEAEAAFLN VYKRLIDVPD PVPALDLGQQ LQLKVQRLHD IETENQKLRE 130 140 150 160 170 180 TLEEYNKEFA EVKNQEVTIK ALKEKIREYE QTLKNQAETI ALEKEQKLQN DFAEKERKLQ 190 200 210 220 230 240 ETQMSTTSKL EEAEHKVQSL QTALEKTRTE LFDLKTKYDE ETTAKADEIE MIMTDLERAN 250 260 270 280 290 300 QRAEVAQREA ETLREQLSSA NHSLQLASQI QKAPDVEQAI EVLTRSSLEV ELAAKEREIA 310 320 330 340 350 360 QLVEDVQRLQ ASLTKLRENS ASQISQLEQQ LSAKNSTLKQ LEEKLKGQAD YEEVKKELNI 370 380 390 400 410 420 LKSMEFAPSE GAGTQDAAKP LEVLLLEKNR SLQSENAALR ISNSDLSGPY STNSISSQSP 430 440 450 460 470 480 LQQSPDVNGM APSPSQSESA GSVSEGEEMD TAEIARQVKE QLIKHNIGQR IFGHYVLGLS 490 500 510 520 530 540 QGSVSEILAR PKPWNKLTVR GKEPFHKMKQ FLSDEQNILA LRSIQGRQRE NPGQSLNRLF 550 560 570 580 590 600 QEVPKRRNGS EGNITTRIRA SETGSDEAIK SILEQAKREL QVQKTAEPAQ PSSASGSGNS 610 620 630 640 650 660 DDAIRSILQQ ARREMEAQQA ALDPALKQAP LSQSDITILT PKLLSTSPMP TVSSYPPLAI 670 680 690 700 710 720 SLKKPSAAPE AGASALPNPP ALKKEAQDAP GLDPQGAADC AQGVLRQVKN EVGRSGAWKD 730 740 750 760 770 780 HWWSAVQPER RNAASSEEAK AEETGGGKEK GSGGSGGGSQ PRAERSQLQG PSSSEYWKEW 790 800 810 820 830 840 PSAESPYSQS SELSLTGASR SETPQNSPLP SSPIVPMSKP TKPSVPPLTP EQYEVYMYQE 850 860 870 880 890 900 VDTIELTRQV KEKLAKNGIC QRIFGEKVLG LSQGSVSDML SRPKPWSKLT QKGREPFIRM 910 920 930 940 950 960 QLWLNGELGQ GVLPVQGQQQ GPVLHSVTSL QDPLQQGCVS SESTPKTSAS CSPAPESPMS 970 980 990 1000 1010 1020 SSESVKSLTE LVQQPCPPIE ASKDSKPPEP SDPPASDSQP TTPLPLSGHS ALSIQELVAM 1030 1040 1050 1060 1070 1080 SPELDTYGIT KRVKEVLTDN NLGQRLFGET ILGLTQGSVS DLLARPKPWH KLSLKGREPF 1090 1100 1110 1120 1130 1140 VRMQLWLNDP NNVEKLMDMK RMEKKAYMKR RHSSVSDSQP CEPPSVGTEY SQGASPQPQH 1150 1160 1170 1180 1190 1200 QLKKPRVVLA PEEKEALKRA YQQKPYPSPK TIEDLATQLN LKTSTVINWF HNYRSRIRRE 1210 1220 1230 1240 1250 1260 LFIEEIQAGS QGQAGASDSP SARSGRAAPS SEGDSCDGVE ATEGPGSADT EEPKSQGEAE 1270 1280 1290 1300 1310 1320 REEVPRPAEQ TEPPPSGTPG PDDARDDDHE GGPVEGPGPL PSPASATATA APAAPEDAAT 1330 1340 1350 1360 1370 1380 SAAAAPGEGP AAPSSAPPPS NSSSSSAPRR PSSLQSLFGL PEAAGARDSR DNPLRKKKAA 1390 1400 NLNSIIHRLE KAASREEPIE WEF
	Isoform 6 [UniParc]. Checksum: EC08BD990BA5321C	FASTA	1,449	157,895
	10 20 30 40 50 60 MLCVAGARLK RELDATATVL ANRQDESEQS RKRLIEQSRE FKKNTPEDLR KQVAPLLKSF 70 80 90 100 110 120 QGEIDALSKR SKEAEAAFLN VYKRLIDVPD PVPALDLGQQ LQLKVQRLHD IETENQKLRE 130 140 150 160 170 180 TLEEYNKEFA EVKNQEVTIK ALKEKIREYE QTLKNQAETI ALEKEQKLQN DFAEKERKLQ 190 200 210 220 230 240 ETQMSTTSKL EEAEHKVQSL QTALEKTRTE LFDLKTKYDE ETTAKADEIE MIMTDLERAN 250 260 270 280 290 300 QRAEVAQREA ETLREQLSSA NHSLQLASQI QKAPDVEQAI EVLTRSSLEV ELAAKEREIA 310 320 330 340 350 360 QLVEDVQRLQ ASLTKLRENS ASQISQLEQQ LSAKNSTLKQ LEEKLKGQAD YEEVKKELNI 370 380 390 400 410 420 LKSMEFAPSE GAGTQDAAKP LEVLLLEKNR SLQSENAALR ISNSDLSGSA RRKGKDQPES 430 440 450 460 470 480 RRPGSLPAPP PSQLPRNPGE QASNTNGTHQ FSPAGLSQDF FSSSLASPSL PLASTGKFAL 490 500 510 520 530 540 NSLLQRQLMQ SFYSKAMQEA GSTSMIFSTG PYSTNSISSQ SPLQQSPDVN GMAPSPSQSE 550 560 570 580 590 600 SAGSVSEGEE MDTAEIARQV KEQLIKHNIG QRIFGHYVLG LSQGSVSEIL ARPKPWNKLT 610 620 630 640 650 660 VRGKEPFHKM KQFLSDEQNI LALRSIQGRQ RAEPAQPSSA SGSGNSDDAI RSILQQARRE 670 680 690 700 710 720 MEAQQAALDP ALKQAPLSQS DITILTPKLL STSPMPTVSS YPPLAISLKK PSAAPEAGAS 730 740 750 760 770 780 ALPNPPALKK EAQDAPGLDP QGAADCAQGV LRQVKNEVGR SGAWKDHWWS AVQPERRNAA 790 800 810 820 830 840 SSEEAKAEET GGGKEKGSGG SGGGSQPRAE RSQLQGPSSS EYWKEWPSAE SPYSQSSELS 850 860 870 880 890 900 LTGASRSETP QNSPLPSSPI VPMSKPTKPS VPPLTPEQYE VYMYQEVDTI ELTRQVKEKL 910 920 930 940 950 960 AKNGICQRIF GEKVLGLSQG SVSDMLSRPK PWSKLTQKGR EPFIRMQLWL NGELGQGVLP 970 980 990 1000 1010 1020 VQGQQQGPVL HSVTSLQDPL QQGCVSSEST PKTSASCSPA PESPMSSSES VKSLTELVQQ 1030 1040 1050 1060 1070 1080 PCPPIEASKD SKPPEPSDPP ASDSQPTTPL PLSGHSALSI QELVAMSPEL DTYGITKRVK 1090 1100 1110 1120 1130 1140 EVLTDNNLGQ RLFGETILGL TQGSVSDLLA RPKPWHKLSL KGREPFVRMQ LWLNDPNNVE 1150 1160 1170 1180 1190 1200 KLMDMKRMEK KAYMKRRHSS VSDSQPCEPP SVGTEYSQGA SPQPQHQLKK PRVVLAPEEK 1210 1220 1230 1240 1250 1260 EALKRAYQQK PYPSPKTIED LATQLNLKTS TVINWFHNYR SRIRRELFIE EIQAGSQGQA 1270 1280 1290 1300 1310 1320 GASDSPSARS GRAAPSSEGD SCDGVEATEG PGSADTEEPK SQGEAEREEV PRPAEQTEPP 1330 1340 1350 1360 1370 1380 PSGTPGPDDA RDDDHEGGPV EGPGPLPSPA SATATAAPAA PEDAATSAAA APGEGPAAPS 1390 1400 1410 1420 1430 1440 SAPPPSNSSS SSAPRRPSSL QSLFGLPEAA GARDSRDNPL RKKKAANLNS IIHRLEKAAS REEPIEWEF
	Isoform 7 [UniParc]. Checksum: D50586280B4D0B81	FASTA	1,347	147,072
	10 20 30 40 50 60 MLCVAGARLK RELDATATVL ANRQDESEQS RKRLIEQSRE FKKNTPEDLR KQVAPLLKSF 70 80 90 100 110 120 QGEIDALSKR SKEAEAAFLN VYKRLIDVPD PVPALDLGQQ LQLKVQRLHD IETENQKLRE 130 140 150 160 170 180 TLEEYNKEFA EVKNQEVTIK ALKEKIREYE QTLKNQAETI ALEKEQKLQN DFAEKERKLQ 190 200 210 220 230 240 ETQMSTTSKL EEAEHKVQSL QTALEKTRTE LFDLKTKYDE ETTAKADEIE MIMTDLERAN 250 260 270 280 290 300 QRAEVAQREA ETLREQLSSA NHSLQLASQI QKAPDVEQAI EVLTRSSLEV ELAAKEREIA 310 320 330 340 350 360 QLVEDVQRLQ ASLTKLRENS ASQISQLEQQ LSAKNSTLKQ LEEKLKGQAD YEEVKKELNI 370 380 390 400 410 420 LKSMEFAPSE GAGTQDAAKP LEVLLLEKNR SLQSENAALR ISNSDLSGPY STNSISSQSP 430 440 450 460 470 480 LQQSPDVNGM APSPSQSESA GSVSEGEEMD TAEIARQVKE QLIKHNIGQR IFGHYVLGLS 490 500 510 520 530 540 QGSVSEILAR PKPWNKLTVR GKEPFHKMKQ FLSDEQNILA LRSIQGRQRA EPAQPSSASG 550 560 570 580 590 600 SGNSDDAIRS ILQQARREME AQQAALDPAL KQAPLSQSDI TILTPKLLST SPMPTVSSYP 610 620 630 640 650 660 PLAISLKKPS AAPEAGASAL PNPPALKKEA QDAPGLDPQG AADCAQGVLR QVKNEVGRSG 670 680 690 700 710 720 AWKDHWWSAV QPERRNAASS EEAKAEETGG GKEKGSGGSG GGSQPRAERS QLQGPSSSEY 730 740 750 760 770 780 WKEWPSAESP YSQSSELSLT GASRSETPQN SPLPSSPIVP MSKPTKPSVP PLTPEQYEVY 790 800 810 820 830 840 MYQEVDTIEL TRQVKEKLAK NGICQRIFGE KVLGLSQGSV SDMLSRPKPW SKLTQKGREP 850 860 870 880 890 900 FIRMQLWLNG ELGQGVLPVQ GQQQGPVLHS VTSLQDPLQQ GCVSSESTPK TSASCSPAPE 910 920 930 940 950 960 SPMSSSESVK SLTELVQQPC PPIEASKDSK PPEPSDPPAS DSQPTTPLPL SGHSALSIQE 970 980 990 1000 1010 1020 LVAMSPELDT YGITKRVKEV LTDNNLGQRL FGETILGLTQ GSVSDLLARP KPWHKLSLKG 1030 1040 1050 1060 1070 1080 REPFVRMQLW LNDPNNVEKL MDMKRMEKKA YMKRRHSSVS DSQPCEPPSV GTEYSQGASP 1090 1100 1110 1120 1130 1140 QPQHQLKKPR VVLAPEEKEA LKRAYQQKPY PSPKTIEDLA TQLNLKTSTV INWFHNYRSR 1150 1160 1170 1180 1190 1200 IRRELFIEEI QAGSQGQAGA SDSPSARSGR AAPSSEGDSC DGVEATEGPG SADTEEPKSQ 1210 1220 1230 1240 1250 1260 GEAEREEVPR PAEQTEPPPS GTPGPDDARD DDHEGGPVEG PGPLPSPASA TATAAPAAPE 1270 1280 1290 1300 1310 1320 DAATSAAAAP GEGPAAPSSA PPPSNSSSSS APRRPSSLQS LFGLPEAAGA RDSRDNPLRK 1330 1340 KKAANLNSII HRLEKAASRE EPIEWEF
	Isoform 11 [UniParc]. Checksum: A399B4B63B891AA6	FASTA	632	72,024
	10 20 30 40 50 60 MAANVGSMFQ YWKRFDLQQL QRELDATATV LANRQDESEQ SRKRLIEQSR EFKKNTPEDL 70 80 90 100 110 120 RKQVAPLLKS FQGEIDALSK RSKEAEAAFL NVYKRLIDVP EVTIKALKEK IREYEQTLKN 130 140 150 160 170 180 QAETIALEKE QKLQNDFAEK ERKLQETQMS TTSKLEEAEH KVQSLQTALE KTRTELFDLK 190 200 210 220 230 240 TKYDEETTAK ADEIEMIMTD LERANQRAEV AQREAETLRE QLSSANHSLQ LASQIQKAPD 250 260 270 280 290 300 VEQAIEVLTR SSLEVELAAK EREIAQLVED VQRLQASLTK LRENSASQIS QLEQQLSAKN 310 320 330 340 350 360 STLKQLEEKL KGQADYEEVK KELNILKSME FAPSEGAGTQ DAAKPLEVLL LEKNRSLQSE 370 380 390 400 410 420 NAALRISNSD LSGRCAELQV RITEAVATAT EQRELIARLE QDLSIIQSIQ RPDAEGAAEH 430 440 450 460 470 480 RLEKIPEPIK EATALFYGPA APASGALPEG QVDSLLSIIS SQRERFRARN QELEAENRLA 490 500 510 520 530 540 QHTLQALQSE LDSLRADNIK LFEKIKFLQS YPGRGSGSDD TELRYSSQYE ERLDPFSSFS 550 560 570 580 590 600 KRERQRKYLS LSPWDKATLS MGRLVLSNKM ARTIGFFYTL FLHCLVFLVL YKLAWSESME 610 620 630 RDCATFCAKK FADHLHKFHE NDNGAAAGDL WQ
	Isoform 4 (CASP) [UniParc]. See Q13948.		–	–
	Isoform 8 [UniParc]. See Q13948.		–	–
	Isoform 9 [UniParc]. See Q13948.		–	–
	Isoform 10 [UniParc]. See Q13948.		–	–

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Human CCAAT displacement protein is homologous to the Drosophila homeoprotein, cut." Neufeld E.J., Skalnik D.G., Lievens P.M.-J., Orkin S.H. Nat. Genet. 1:50-55(1992) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORMS 1 AND 2). Tissue: Umbilical vein.
[2]	"Complete sequencing and characterization of 21,243 full-length human cDNAs." Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H., Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S. , Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K., Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A., Sudo H., Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M., Takahashi M., Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y., Abe K., Kamihara K., Katsuta N., Sato K., Tanikawa M., Yamazaki M., Ninomiya K., Ishibashi T., Yamashita H., Murakawa K., Fujimori K., Tanai H., Kimata M., Watanabe M., Hiraoka S., Chiba Y., Ishida S., Ono Y., Takiguchi S., Watanabe S., Yosida M., Hotuta T., Kusano J., Kanehori K., Takahashi-Fujii A., Hara H., Tanase T.-O., Nomura Y., Togiya S., Komai F., Hara R., Takeuchi K., Arita M., Imose N., Musashino K., Yuuki H., Oshima A., Sasaki N., Aotsuka S., Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S., Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O., Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H., Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B., Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y., Fujimori Y., Komiyama M., Tashiro H., Tanigami A., Fujiwara T., Ono T., Yamada K., Fujii Y., Ozaki K., Hirao M., Ohmori Y., Kawabata A., Hikiji T., Kobatake N., Inagaki H., Ikema Y., Okamoto S., Okitani R., Kawakami T., Noguchi S., Itoh T., Shigeta K., Senba T., Matsumura K., Nakajima Y., Mizuno T., Morinaga M., Sasaki M., Togashi T., Oyama M., Hata H., Watanabe M., Komatsu T., Mizushima-Sugano J., Satoh T., Shirai Y., Takahashi Y., Nakagawa K., Okumura K., Nagase T., Nomura N., Kikuchi H., Masuho Y., Yamashita R., Nakai K., Yada T., Nakamura Y., Ohara O., Isogai T., Sugano S. Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 11). Tissue: Brain.
[3]	"The DNA sequence of human chromosome 7." Hillier L.W., Fulton R.S., Fulton L.A., Graves T.A., Pepin K.H., Wagner-McPherson C., Layman D., Maas J., Jaeger S., Walker R., Wylie K., Sekhon M., Becker M.C., O'Laughlin M.D., Schaller M.E., Fewell G.A., Delehaunty K.D., Miner T.L. , Nash W.E., Cordes M., Du H., Sun H., Edwards J., Bradshaw-Cordum H., Ali J., Andrews S., Isak A., Vanbrunt A., Nguyen C., Du F., Lamar B., Courtney L., Kalicki J., Ozersky P., Bielicki L., Scott K., Holmes A., Harkins R., Harris A., Strong C.M., Hou S., Tomlinson C., Dauphin-Kohlberg S., Kozlowicz-Reilly A., Leonard S., Rohlfing T., Rock S.M., Tin-Wollam A.-M., Abbott A., Minx P., Maupin R., Strowmatt C., Latreille P., Miller N., Johnson D., Murray J., Woessner J.P., Wendl M.C., Yang S.-P., Schultz B.R., Wallis J.W., Spieth J., Bieri T.A., Nelson J.O., Berkowicz N., Wohldmann P.E., Cook L.L., Hickenbotham M.T., Eldred J., Williams D., Bedell J.A., Mardis E.R., Clifton S.W., Chissoe S.L., Marra M.A., Raymond C., Haugen E., Gillett W., Zhou Y., James R., Phelps K., Iadanoto S., Bubb K., Simms E., Levy R., Clendenning J., Kaul R., Kent W.J., Furey T.S., Baertsch R.A., Brent M.R., Keibler E., Flicek P., Bork P., Suyama M., Bailey J.A., Portnoy M.E., Torrents D., Chinwalla A.T., Gish W.R., Eddy S.R., McPherson J.D., Olson M.V., Eichler E.E., Green E.D., Waterston R.H., Wilson R.K. Nature 424:157-164(2003) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
[4]	"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)." The MGC Project Team Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 3). Tissue: Duodenum.
[5]	"Large-scale sequencing of two regions in human chromosome 7q22: analysis of 650 kb of genomic sequence around the EPO and CUTL1 loci reveals 17 genes." Gloeckner G., Scherer S., Schattevoy R., Boright A.P., Weber J., Tsui L.-C., Rosenthal A. Genome Res. 8:1060-1073(1998) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 48-224 (ISOFORMS 1/2/3).
[6]	"Exon/intron structure and alternative transcripts of the CUTL1 gene." Rong Zeng W., Soucie E., Sung Moon N., Martin-Soudant N., Berube G., Leduy L., Nepveu A. Gene 241:75-85(2000) [PubMed] [Europe PMC] [Abstract] Cited for: ALTERNATIVE SPLICING (ISOFORMS 5; 6 AND 7).
[7]	"ATM and ATR substrate analysis reveals extensive protein networks responsive to DNA damage." Matsuoka S., Ballif B.A., Smogorzewska A., McDonald E.R. III, Hurov K.E., Luo J., Bakalarski C.E., Zhao Z., Solimini N., Lerenthal Y., Shiloh Y., Gygi S.P., Elledge S.J. Science 316:1160-1166(2007) [PubMed] [Europe PMC] [Abstract] Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]. Tissue: Embryonic kidney.
[8]	"A quantitative atlas of mitotic phosphorylation." Dephoure N., Zhou C., Villen J., Beausoleil S.A., Bakalarski C.E., Elledge S.J., Gygi S.P. Proc. Natl. Acad. Sci. U.S.A. 105:10762-10767(2008) [PubMed] [Europe PMC] [Abstract] Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]. Tissue: Cervix carcinoma.
[9]	"Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions." Mayya V., Lundgren D.H., Hwang S.-I., Rezaul K., Wu L., Eng J.K., Rodionov V., Han D.K. Sci. Signal. 2:RA46-RA46(2009) [PubMed] [Europe PMC] [Abstract] Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]. Tissue: Leukemic T-cell.
[10]	"Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis." Olsen J.V., Vermeulen M., Santamaria A., Kumar C., Miller M.L., Jensen L.J., Gnad F., Cox J., Jensen T.S., Nigg E.A., Brunak S., Mann M. Sci. Signal. 3:RA3-RA3(2010) [PubMed] [Europe PMC] [Abstract] Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-763, MASS SPECTROMETRY. Tissue: Cervix carcinoma.
[11]	"Initial characterization of the human central proteome." Burkard T.R., Planyavsky M., Kaupe I., Breitwieser F.P., Buerckstuemmer T., Bennett K.L., Superti-Furga G., Colinge J. BMC Syst. Biol. 5:17-17(2011) [PubMed] [Europe PMC] [Abstract] Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	M74099 mRNA. No translation available. AK122726 mRNA. Translation: BAG53691.1. AC005072 Genomic DNA. No translation available. AC005086 Genomic DNA. Translation: AAP22331.1. AC005088 Genomic DNA. No translation available. AC005096 Genomic DNA. Translation: AAS07410.1. AC005103 Genomic DNA. Translation: AAS07388.1. AC092788 Genomic DNA. Translation: AAS07523.1. BC066592 mRNA. Translation: AAH66592.1. AF047825 Genomic DNA. Translation: AAC78778.1.
IPI	IPI00026673. IPI00419894. IPI00472247. IPI00736943. IPI00741668. IPI00742111. IPI00982754.
RefSeq	NP_001189472.1. NM_001202543.1. NP_001189473.1. NM_001202544.1. NP_001189474.1. NM_001202545.1. NP_852477.1. NM_181500.2. NP_853530.2. NM_181552.3.
UniGene	Hs.191482.
3D structure databases
ProteinModelPortal	P39880.
SMR	P39880. Positions 547-635, 934-1024, 1116-1301.
ModBase	Search...
Protein-protein interaction databases
IntAct	P39880. 7 interactions.
MINT	MINT-271237.
STRING	9606.ENSP00000292535.
PTM databases
PhosphoSite	P39880.
Polymorphism databases
DMDM	296439379.
Proteomic databases
PRIDE	P39880.
Protocols and materials databases
DNASU	1523.
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
Ensembl	ENST00000292535; ENSP00000292535; ENSG00000257923. ENST00000360264; ENSP00000353401; ENSG00000257923. ENST00000425244; ENSP00000409745; ENSG00000257923. ENST00000546411; ENSP00000450125; ENSG00000257923. ENST00000549414; ENSP00000446630; ENSG00000257923. ENST00000550008; ENSP00000447373; ENSG00000257923. ENST00000556210; ENSP00000451558; ENSG00000257923. ENST00000562419; ENSP00000456964; ENSG00000259938. ENST00000562858; ENSP00000456303; ENSG00000259938. ENST00000565244; ENSP00000456251; ENSG00000259938. ENST00000566988; ENSP00000455160; ENSG00000259938. ENST00000568052; ENSP00000458017; ENSG00000259938. ENST00000568166; ENSP00000456980; ENSG00000259938. ENST00000569498; ENSP00000455398; ENSG00000259938.
GeneID	1523.
KEGG	hsa:1523.
UCSC	uc003uys.4. human. uc003uyx.4. human.
Organism-specific databases
CTD	1523.
GeneCards	GC07P101459.
HGNC	HGNC:2557. CUX1.
HPA	HPA003277. HPA003317.
MIM	116896. gene.
neXtProt	NX_P39880.
PharmGKB	PA162382924.
GenAtlas	Search...
Phylogenomic databases
HOVERGEN	HBG051268.
KO	K09313.
OMA	PPIETSK.
Enzyme and pathway databases
Reactome	REACT_116125. Disease.
Gene expression databases
ArrayExpress	P39880.
Bgee	P39880.
CleanEx	HS_CUX1.
Genevestigator	P39880.
Family and domain databases
Gene3D	1.10.10.60. 1 hit. 1.10.260.40. 3 hits.
InterPro	IPR003350. Hmoeo_CUT. IPR017970. Homeobox_CS. IPR001356. Homeodomain. IPR009057. Homeodomain-like. IPR010982. Lambda_DNA-bd_dom. [Graphical view]
Pfam	PF02376. CUT. 3 hits. PF00046. Homeobox. 1 hit. [Graphical view]
SMART	SM00389. HOX. 1 hit. [Graphical view]
SUPFAM	SSF46689. Homeodomain_like. 1 hit. SSF47413. Lambda_like_DNA. 3 hits.
PROSITE	PS51042. CUT. 3 hits. PS00027. HOMEOBOX_1. 1 hit. PS50071. HOMEOBOX_2. 1 hit. [Graphical view]
ProtoNet	Search...
Other
ChiTaRS	CUX1. human.
GenomeRNAi	1523.
NextBio	35535424.
PMAP-CutDB	P39880.
SOURCE	Search...

Entry information

Entry name

CUX1_HUMAN

Accession

Primary (citable) accession number: P39880
Secondary accession number(s): B3KV79 , J3KQV9, Q6NYH4, Q75LE5, Q75MT2, Q75MT3, Q86UJ7, Q9UEV5

Entry history

Integrated into UniProtKB/Swiss-Prot:	February 1, 1995
Last sequence update:	May 18, 2010
Last modified:	May 1, 2013
This is version 130 of the entry and version 3 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Chordata Protein Annotation Program

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.