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Protein

Putative hydrolase YbeM

Gene

ybeM

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein uncertaini

Functioni

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei40 – 401Proton acceptorPROSITE-ProRule annotation
Active sitei110 – 1101Proton donorPROSITE-ProRule annotation
Active sitei147 – 1471NucleophilePROSITE-ProRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Hydrolase

Enzyme and pathway databases

BioCyciEcoCyc:G6348-MONOMER.
ECOL316407:JW0620-MONOMER.
ECOL316407:JW0621-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Putative hydrolase YbeM (EC:3.5.-.-)
Gene namesi
Name:ybeM
Ordered Locus Names:b4581, JW0620/JW0621
ORF Names:b0625, b0626
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000318 Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG13162. ybeM.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 262262Putative hydrolase YbeMPRO_0000213258Add
BLAST

Proteomic databases

PRIDEiP39874.

Interactioni

Protein-protein interaction databases

BioGridi4260640. 6 interactions.
IntActiP39874. 2 interactions.
STRINGi316407.4062249.

Structurei

3D structure databases

ProteinModelPortaliP39874.
SMRiP39874. Positions 3-256.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini1 – 260260CN hydrolasePROSITE-ProRule annotationAdd
BLAST

Sequence similaritiesi

Contains 1 CN hydrolase domain.PROSITE-ProRule annotation

Phylogenomic databases

eggNOGiENOG4107QPI. Bacteria.
COG0388. LUCA.
HOGENOMiHOG000222700.
InParanoidiP39874.
OMAiECGTRNI.
PhylomeDBiP39874.

Family and domain databases

Gene3Di3.60.110.10. 1 hit.
InterProiIPR003010. C-N_Hydrolase.
IPR001110. UPF0012_CS.
[Graphical view]
PfamiPF00795. CN_hydrolase. 1 hit.
[Graphical view]
SUPFAMiSSF56317. SSF56317. 1 hit.
PROSITEiPS50263. CN_HYDROLASE. 1 hit.
PS01227. UPF0012. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P39874-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLVAAGQFAV TSVWEKNAEI CASLMAQAAE NDASLFALPE ALLARDDHDA
60 70 80 90 100
DLSVKSAQLL EGEFLGRLRR ESKRNMMTTI LTIHVPSTPG RAWNMLVALQ
110 120 130 140 150
AGNIVARYAK LHLYDAFAIQ ESRRVDAGNE IAPLLEVEGM KVGLMTCYDL
160 170 180 190 200
RFPELALAQA LQGAEILVLP AAWVRGPLKE HHWSTLLAAR ALDTTCYMVA
210 220 230 240 250
AGECGNKNIG QSRIIDPFGV TIAAASEMPA LIMAEVTPER VRQVRAQLPV
260
LNNRRFAPPQ LL
Length:262
Mass (Da):28,625
Last modified:April 27, 2001 - v3
Checksum:i116B11439F83EAD2
GO

Sequence cautioni

The sequence AAA81032.1 differs from that shown. Reason: Frameshift at position 67. Curated
The sequence AAB40825.1 differs from that shown. Reason: Frameshift at position 67. Curated
The sequence AAB40826.1 differs from that shown. Reason: Frameshift at position 67. Curated
The sequence BAA35268.1 differs from that shown. Reason: Frameshift at position 67. Curated
The sequence BAA35269.1 differs from that shown. Reason: Frameshift at position 67. Curated
The sequence U00096 differs from that shown. Reason: Frameshift at position 67. Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U82598 Genomic DNA. Translation: AAB40825.1. Frameshift.
U82598 Genomic DNA. Translation: AAB40826.1. Frameshift.
U00096 Genomic DNA. No translation available.
AP009048 Genomic DNA. Translation: BAA35268.1. Frameshift.
AP009048 Genomic DNA. Translation: BAA35269.1. Frameshift.
D28497 Genomic DNA. No translation available.
U38811 Genomic DNA. Translation: AAA81032.1. Frameshift.
PIRiG64796.
H64796.

Genome annotation databases

EnsemblBacteriaiBAA35268; BAA35268; BAA35268.
BAA35269; BAA35269; BAA35269.
KEGGiecj:JW0620.
ecj:JW0621.
PATRICi48660478. VBIEscCol107702_0629.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U82598 Genomic DNA. Translation: AAB40825.1. Frameshift.
U82598 Genomic DNA. Translation: AAB40826.1. Frameshift.
U00096 Genomic DNA. No translation available.
AP009048 Genomic DNA. Translation: BAA35268.1. Frameshift.
AP009048 Genomic DNA. Translation: BAA35269.1. Frameshift.
D28497 Genomic DNA. No translation available.
U38811 Genomic DNA. Translation: AAA81032.1. Frameshift.
PIRiG64796.
H64796.

3D structure databases

ProteinModelPortaliP39874.
SMRiP39874. Positions 3-256.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi4260640. 6 interactions.
IntActiP39874. 2 interactions.
STRINGi316407.4062249.

Proteomic databases

PRIDEiP39874.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiBAA35268; BAA35268; BAA35268.
BAA35269; BAA35269; BAA35269.
KEGGiecj:JW0620.
ecj:JW0621.
PATRICi48660478. VBIEscCol107702_0629.

Organism-specific databases

EcoGeneiEG13162. ybeM.

Phylogenomic databases

eggNOGiENOG4107QPI. Bacteria.
COG0388. LUCA.
HOGENOMiHOG000222700.
InParanoidiP39874.
OMAiECGTRNI.
PhylomeDBiP39874.

Enzyme and pathway databases

BioCyciEcoCyc:G6348-MONOMER.
ECOL316407:JW0620-MONOMER.
ECOL316407:JW0621-MONOMER.

Family and domain databases

Gene3Di3.60.110.10. 1 hit.
InterProiIPR003010. C-N_Hydrolase.
IPR001110. UPF0012_CS.
[Graphical view]
PfamiPF00795. CN_hydrolase. 1 hit.
[Graphical view]
SUPFAMiSSF56317. SSF56317. 1 hit.
PROSITEiPS50263. CN_HYDROLASE. 1 hit.
PS01227. UPF0012. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: K12 / W3110 / ATCC 27325 / DSM 5911.
  2. "Sequence of minutes 4-25 of Escherichia coli."
    Chung E., Allen E., Araujo R., Aparicio A.M., Davis K., Duncan M., Federspiel N., Hyman R., Kalman S., Komp C., Kurdi O., Lew H., Lin D., Namath A., Oefner P., Roberts D., Schramm S., Davis R.W.
    Submitted (JAN-1997) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: K12 / MG1655 / ATCC 47076.
  3. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: K12 / MG1655 / ATCC 47076.
  4. "Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110."
    Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S., Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T.
    Mol. Syst. Biol. 2:E1-E5(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: K12 / W3110 / ATCC 27325 / DSM 5911.
  5. "Cloning, sequencing, and characterization of multicopy suppressors of a mukB mutation in Escherichia coli."
    Yamanaka K., Mitani T., Ogura T., Niki H., Hiraga S.
    Mol. Microbiol. 13:301-312(1994) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1-51.
    Strain: K12.
  6. Robison K., O'Keeffe T., Church G.M.
    Submitted (OCT-1995) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 31-78.
    Strain: K12 / EMG2.
  7. Rudd K.E.
    Unpublished observations (JAN-2000)
    Cited for: CONCEPTUAL TRANSLATION.

Entry informationi

Entry nameiYBEM_ECOLI
AccessioniPrimary (citable) accession number: P39874
Secondary accession number(s): P77104, P77192
Entry historyi
Integrated into UniProtKB/Swiss-Prot: February 1, 1995
Last sequence update: April 27, 2001
Last modified: January 20, 2016
This is version 119 of the entry and version 3 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Caution

Could be the product of a pseudogene.Curated

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Escherichia coli
    Escherichia coli (strain K12): entries and cross-references to EcoGene
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.