Reviewed, UniProtKB/Swiss-Prot P39852 (CAPC_STAAU)

Names and origin

Protein names

Recommended name:
    Putative tyrosine-protein phosphatase capC
    EC=3.1.3.48

Gene names

Name:

capC

Organism

Staphylococcus aureus

Taxonomic identifier

1280 [NCBI]

Taxonomic lineage

Bacteria › Firmicutes › Bacillales › Staphylococcus

Protein attributes

Sequence length	255 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Function	Required for the biosynthesis of type 1 capsular polysaccharide.
Catalytic activity	Protein tyrosine phosphate + H2O = protein tyrosine + phosphate.
Pathway	Capsule biogenesis; capsule polysaccharide biosynthesis.
Sequence similarities	Belongs to the cpsB/capC family.

Ontologies

Keywords
Biological process	Capsule biogenesis/degradation Exopolysaccharide synthesis
Molecular function	Hydrolase Protein phosphatase
Gene Ontology (GO)
Biological process	polysaccharide biosynthetic process Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	manganese ion binding Inferred from electronic annotation. Source: InterPro protein tyrosine phosphatase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 255	255	Putative tyrosine-protein phosphatase capC		PRO_0000057886

Sequences

	Sequence		Length	Mass (Da)
	P39852-1 [UniParc]. Last modified February 1, 1995. Version 1. Checksum: C9DFC47BE8AD599F	FASTA	255	29,377
	10 20 30 40 50 60 MVDIHNHILV DVDDGPKSIN EAIELLKQAQ SENVTDIVAT PHHLHKRYSN DIEKVKIKLN 70 80 90 100 110 120 ELKNNSEIKK LGLNLYVGQE IRITDQIIEG IKNKEIEGIN ESRYLLIEFP SNEIPYYTNQ 130 140 150 160 170 180 LFYELQTMGY IPIIAHPERN KAIVQNLDLL FELINGGALS QITASSLLGD FGNNIRKLSL 190 200 210 220 230 240 KMIDSNLAHF IASDAHSITN RPFMLKQLFN DRKLKAYYEE LESYLKNGKL VLTNERISKQ 250 IPTQDYKQKK WFGLL

References

[1]

"Sequence analysis and molecular characterization of genes required for the biosynthesis of type 1 capsular polysaccharide in Staphylococcus aureus." Lin W.S., Cunneen T., Lee C.Y. J. Bacteriol. 176:7005-7016(1994) [PubMed: 7961465] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]. Strain: ATCC 49951 / M / NCTC 10649.

Cross-references

Sequence databases
EMBLGenBankDDBJ	U10927 Genomic DNA. Translation: AAA64642.1.
3D structure databases
ModBase	Search...
Enzyme and pathway databases
BRENDA	3.1.3.48. 95.
Family and domain databases
InterPro	IPR016667. Caps_polysacc_synth_CpsB/CapC. IPR004013. PHP_C. [Graphical view]
Pfam	PF02811. PHP. 1 hit. [Graphical view]
PIRSF	PIRSF016557. Caps_synth_CpsB. 1 hit.
ProtoNet	Search...

Entry information

Entry name

CAPC_STAAU

Accession

Primary (citable) accession number: P39852

Entry history

Integrated into UniProtKB/Swiss-Prot:	February 1, 1995
Last sequence update:	February 1, 1995
Last modified:	June 16, 2009
This is version 34 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)