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P39851

- CAPB_STAAU

UniProt

P39851 - CAPB_STAAU

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Protein

Putative tyrosine-protein kinase CapB

Gene
capB
Organism
Staphylococcus aureus
Status
Reviewed - Annotation score: 3 out of 5 - Protein inferred from homologyi

Functioni

Required for the biosynthesis of type 1 capsular polysaccharide.

Catalytic activityi

ATP + a [protein]-L-tyrosine = ADP + a [protein]-L-tyrosine phosphate.

Pathwayi

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-KW
  2. enzyme regulator activity Source: InterPro
  3. non-membrane spanning protein tyrosine kinase activity Source: UniProtKB-EC

GO - Biological processi

  1. capsule polysaccharide biosynthetic process Source: UniProtKB-UniPathway
Complete GO annotation...

Keywords - Molecular functioni

Kinase, Transferase, Tyrosine-protein kinase

Keywords - Biological processi

Capsule biogenesis/degradation, Exopolysaccharide synthesis

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Enzyme and pathway databases

UniPathwayiUPA00934.

Protein family/group databases

TCDBi8.A.3.2.1. the cytoplasmic membrane-periplasmic auxiliary-1 (mpa1) protein with cytoplasmic (c) domain (mpa1-c or mpa1+c) family.

Names & Taxonomyi

Protein namesi
Recommended name:
Putative tyrosine-protein kinase CapB (EC:2.7.10.2)
Gene namesi
Name:capB
OrganismiStaphylococcus aureus
Taxonomic identifieri1280 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesStaphylococcus

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 228228Putative tyrosine-protein kinase CapBPRO_0000217234Add
BLAST

Structurei

3D structure databases

ProteinModelPortaliP39851.
SMRiP39851. Positions 1-228.

Family & Domainsi

Sequence similaritiesi

Belongs to the CpsD/CapB family.

Family and domain databases

Gene3Di3.40.50.300. 1 hit.
InterProiIPR025669. AAA_dom.
IPR005702. EPS_synthesis.
IPR027417. P-loop_NTPase.
[Graphical view]
PfamiPF13614. AAA_31. 1 hit.
[Graphical view]
SUPFAMiSSF52540. SSF52540. 1 hit.
TIGRFAMsiTIGR01007. eps_fam. 1 hit.

Sequencei

Sequence statusi: Complete.

P39851-1 [UniParc]FASTAAdd to Basket

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MAKKKSTISP LYVHDKPKST ISEKFRGIRS NIMFSNAENE IKSLLITSEK    50
SASGKSILSA NIAVTYAQAG YKTLIIDGDM RKPTQHYIFD LPNNSGLSNL 100
IINKTTYSDS IKETRVENLN VLTAGPTPPN PSELIASSKF ATIFNELLNH 150
YDFIVIDTPP INTVTDAQVY ARIVKNCVLV IDAEKNNKSE VKKAKGLLTK 200
AGGKVLGAVL NKMPIDKNSS YYYYYGED 228
Length:228
Mass (Da):25,176
Last modified:February 1, 1995 - v1
Checksum:i777A4395AA8D7F67
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
U10927 Genomic DNA. Translation: AAA64641.1.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
U10927 Genomic DNA. Translation: AAA64641.1 .

3D structure databases

ProteinModelPortali P39851.
SMRi P39851. Positions 1-228.
ModBasei Search...
MobiDBi Search...

Protein family/group databases

TCDBi 8.A.3.2.1. the cytoplasmic membrane-periplasmic auxiliary-1 (mpa1) protein with cytoplasmic (c) domain (mpa1-c or mpa1+c) family.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Enzyme and pathway databases

UniPathwayi UPA00934 .

Family and domain databases

Gene3Di 3.40.50.300. 1 hit.
InterProi IPR025669. AAA_dom.
IPR005702. EPS_synthesis.
IPR027417. P-loop_NTPase.
[Graphical view ]
Pfami PF13614. AAA_31. 1 hit.
[Graphical view ]
SUPFAMi SSF52540. SSF52540. 1 hit.
TIGRFAMsi TIGR01007. eps_fam. 1 hit.
ProtoNeti Search...

Publicationsi

  1. "Sequence analysis and molecular characterization of genes required for the biosynthesis of type 1 capsular polysaccharide in Staphylococcus aureus."
    Lin W.S., Cunneen T., Lee C.Y.
    J. Bacteriol. 176:7005-7016(1994) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
    Strain: ATCC 49951 / M / NCTC 10649.

Entry informationi

Entry nameiCAPB_STAAU
AccessioniPrimary (citable) accession number: P39851
Entry historyi
Integrated into UniProtKB/Swiss-Prot: February 1, 1995
Last sequence update: February 1, 1995
Last modified: April 16, 2014
This is version 62 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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