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Protein

Putative mannose-6-phosphate isomerase YvyI

Gene

yvyI

Organism
Bacillus subtilis (strain 168)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Functioni

Catalytic activityi

D-mannose 6-phosphate = D-fructose 6-phosphate.

Cofactori

Zn2+Note: Binds 1 zinc ion per subunit.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Metal bindingi98Zinc1 Publication1
Metal bindingi116Zinc1 Publication1
Metal bindingi173Zinc1 Publication1
Active sitei193By similarity1

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Isomerase

Keywords - Biological processi

Carbohydrate metabolism

Keywords - Ligandi

Metal-binding, Zinc

Enzyme and pathway databases

BioCyciBSUB:BSU35790-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Putative mannose-6-phosphate isomerase YvyI (EC:5.3.1.8)
Alternative name(s):
Phosphohexomutase
Phosphomannose isomerase
Short name:
PMI
Gene namesi
Name:yvyI
Synonyms:pmi
Ordered Locus Names:BSU35790
OrganismiBacillus subtilis (strain 168)
Taxonomic identifieri224308 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesBacillaceaeBacillus
Proteomesi
  • UP000001570 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001942281 – 316Putative mannose-6-phosphate isomerase YvyIAdd BLAST316

Proteomic databases

PaxDbiP39841.
PRIDEiP39841.

Interactioni

Protein-protein interaction databases

IntActiP39841. 1 interactor.
STRINGi224308.Bsubs1_010100019361.

Structurei

Secondary structure

1316
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details
Feature keyPosition(s)DescriptionActionsGraphical viewLength
Beta strandi6 – 9Combined sources4
Beta strandi11 – 14Combined sources4
Helixi21 – 26Combined sources6
Beta strandi31 – 41Combined sources11
Turni55 – 58Combined sources4
Helixi61 – 67Combined sources7
Helixi69 – 72Combined sources4
Beta strandi82 – 91Combined sources10
Beta strandi95 – 97Combined sources3
Helixi101 – 107Combined sources7
Turni108 – 110Combined sources3
Beta strandi116 – 123Combined sources8
Beta strandi128 – 133Combined sources6
Helixi138 – 146Combined sources9
Helixi150 – 153Combined sources4
Beta strandi154 – 158Combined sources5
Beta strandi164 – 167Combined sources4
Beta strandi173 – 175Combined sources3
Beta strandi177 – 187Combined sources11
Beta strandi192 – 195Combined sources4
Helixi211 – 217Combined sources7
Beta strandi230 – 234Combined sources5
Beta strandi237 – 244Combined sources8
Beta strandi249 – 261Combined sources13
Beta strandi268 – 281Combined sources14
Beta strandi284 – 289Combined sources6
Beta strandi293 – 296Combined sources4
Beta strandi303 – 315Combined sources13

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
1QWRX-ray1.80A/B1-316[»]
ProteinModelPortaliP39841.
SMRiP39841.
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiP39841.

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiENOG4105DG6. Bacteria.
COG1482. LUCA.
HOGENOMiHOG000054245.
InParanoidiP39841.
KOiK01809.
OMAiTMINSGD.
PhylomeDBiP39841.

Family and domain databases

Gene3Di2.60.120.10. 2 hits.
InterProiIPR001250. Man6P_Isoase-1.
IPR014628. Man6P_isomerase_Firm_short.
IPR014710. RmlC-like_jellyroll.
IPR011051. RmlC_Cupin.
[Graphical view]
PfamiPF01238. PMI_typeI. 1 hit.
[Graphical view]
PIRSFiPIRSF036894. PMI_Firm_short. 1 hit.
SUPFAMiSSF51182. SSF51182. 1 hit.
TIGRFAMsiTIGR00218. manA. 2 hits.

Sequencei

Sequence statusi: Complete.

P39841-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTQSPIFLTP VFKEKIWGGT ALRDRFGYSI PSESTGECWA ISAHPKGPST
60 70 80 90 100
VANGPYKGKT LIELWEEHRE VFGGVEGDRF PLLTKLLDVK EDTSIKVHPD
110 120 130 140 150
DYYAGENEEG ELGKTECWYI IDCKENAEII YGHTARSKTE LVTMINSGDW
160 170 180 190 200
EGLLRRIKIK PGDFYYVPSG TLHALCKGAL VLETQQNSDA TYRVYDYDRL
210 220 230 240 250
DSNGSPRELH FAKAVNAATV PHVDGYIDES TESRKGITIK TFVQGEYFSV
260 270 280 290 300
YKWDINGEAE MAQDESFLIC SVIEGSGLLK YEDKTCPLKK GDHFILPAQM
310
PDFTIKGTCT LIVSHI
Length:316
Mass (Da):35,428
Last modified:February 1, 1995 - v1
Checksum:i21E6FF26E7CF922F
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U02562 Genomic DNA. Translation: AAA67856.1.
D45048 Genomic DNA. Translation: BAA08088.1.
AL009126 Genomic DNA. Translation: CAB15596.1.
PIRiA69680.
RefSeqiNP_391460.1. NC_000964.3.
WP_003244253.1. NZ_JNCM01000034.1.

Genome annotation databases

EnsemblBacteriaiCAB15596; CAB15596; BSU35790.
GeneIDi936815.
KEGGibsu:BSU35790.
PATRICi18979174. VBIBacSub10457_3749.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U02562 Genomic DNA. Translation: AAA67856.1.
D45048 Genomic DNA. Translation: BAA08088.1.
AL009126 Genomic DNA. Translation: CAB15596.1.
PIRiA69680.
RefSeqiNP_391460.1. NC_000964.3.
WP_003244253.1. NZ_JNCM01000034.1.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
1QWRX-ray1.80A/B1-316[»]
ProteinModelPortaliP39841.
SMRiP39841.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

IntActiP39841. 1 interactor.
STRINGi224308.Bsubs1_010100019361.

Proteomic databases

PaxDbiP39841.
PRIDEiP39841.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiCAB15596; CAB15596; BSU35790.
GeneIDi936815.
KEGGibsu:BSU35790.
PATRICi18979174. VBIBacSub10457_3749.

Phylogenomic databases

eggNOGiENOG4105DG6. Bacteria.
COG1482. LUCA.
HOGENOMiHOG000054245.
InParanoidiP39841.
KOiK01809.
OMAiTMINSGD.
PhylomeDBiP39841.

Enzyme and pathway databases

BioCyciBSUB:BSU35790-MONOMER.

Miscellaneous databases

EvolutionaryTraceiP39841.

Family and domain databases

Gene3Di2.60.120.10. 2 hits.
InterProiIPR001250. Man6P_Isoase-1.
IPR014628. Man6P_isomerase_Firm_short.
IPR014710. RmlC-like_jellyroll.
IPR011051. RmlC_Cupin.
[Graphical view]
PfamiPF01238. PMI_typeI. 1 hit.
[Graphical view]
PIRSFiPIRSF036894. PMI_Firm_short. 1 hit.
SUPFAMiSSF51182. SSF51182. 1 hit.
TIGRFAMsiTIGR00218. manA. 2 hits.
ProtoNetiSearch...

Entry informationi

Entry nameiMANA3_BACSU
AccessioniPrimary (citable) accession number: P39841
Entry historyi
Integrated into UniProtKB/Swiss-Prot: February 1, 1995
Last sequence update: February 1, 1995
Last modified: November 2, 2016
This is version 122 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome

Documents

  1. Bacillus subtilis
    Bacillus subtilis (strain 168): entries, gene names and cross-references to SubtiList
  2. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  3. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.